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Network neighborhood for query Sequence : IPP4_HUMAN

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IPP4_HUMAN
SwissProt Accessions	O14990, Q5H958	Gene names	PPP1R2P9
Domain Architecture	No domain graphic available
Description	Type-1 protein phosphatase inhibitor 4 (I-4) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IPP4_HUMAN
θ value	3.1125e-93 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	O14990, Q5H958	Gene names	PPP1R2P9
Domain Architecture	No domain graphic available
Description	Type-1 protein phosphatase inhibitor 4 (I-4) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9).

IPP2_HUMAN
θ value	3.3877e-31 (rank : 2)	NC score	0.883199 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P41236	Gene names	PPP1R2, IPP2
Domain Architecture
Description	Protein phosphatase inhibitor 2 (IPP-2).

IPP2_MOUSE
θ value	5.77852e-31 (rank : 3)	NC score	0.869095 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

CSTN1_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.058109 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	O94985	Gene names	CLSTN1, CS1, KIAA0911
Domain Architecture	No domain graphic available
Description	Calsyntenin-1 precursor.

IF31_MOUSE
θ value	0.21417 (rank : 5)	NC score	0.123974 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q66JS6, Q8BUW6	Gene names	Eif3s1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha).

KI21A_MOUSE
θ value	0.21417 (rank : 6)	NC score	0.033974 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	1317	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

IF31_HUMAN
θ value	0.47712 (rank : 7)	NC score	0.122530 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

M4K4_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.018115 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	1589	Shared Neighborhood Hits	14
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.018495 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	1560	Shared Neighborhood Hits	14
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

TRHY_HUMAN
θ value	0.47712 (rank : 10)	NC score	0.030971 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	1385	Shared Neighborhood Hits	15
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

AN32B_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.036818 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

CCD96_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.048833 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	595	Shared Neighborhood Hits	13
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CSTN1_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.051937 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPL2	Gene names	Clstn1, Cs1, Cstn1
Domain Architecture
Description	Calsyntenin-1 precursor.

RN168_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.051224 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	370	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

CALD1_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.026454 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	959	Shared Neighborhood Hits	13
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

WRN_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.029288 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

ROCK1_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.013474 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	2000	Shared Neighborhood Hits	16
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

CROCC_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.024845 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	1460	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GSDM1_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.031519 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EST1	Gene names	Gsdm1, Gsdm
Domain Architecture	No domain graphic available
Description	Gasdermin.

SMCE1_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.037088 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

A4_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.023582 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	275	Shared Neighborhood Hits	8
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CEP35_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.035475 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	811	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

FAM9A_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.037770 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	138	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

MTMR7_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.016542 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MY18A_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.022249 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	1989	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CS007_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.020756 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	401	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

PESC_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.028903 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQ61, Q542F0	Gene names	Pes1
Domain Architecture
Description	Pescadillo homolog 1.

RN168_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.042045 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	440	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

WASF2_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.022370 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	280	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.022085 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	315	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

CCD82_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.020954 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

GP101_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.002481 (rank : 40)
Query Neighborhood Hits	39	Target Neighborhood Hits	913	Shared Neighborhood Hits	3
SwissProt Accessions	Q96P66, Q8NG93	Gene names	GPR101
Domain Architecture
Description	Probable G-protein coupled receptor 101.

LYST_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.012615 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	286	Shared Neighborhood Hits	5
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

MDC1_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.014834 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	998	Shared Neighborhood Hits	12
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MMTA2_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.023410 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BU76, Q6P5Y0, Q6ZTZ6, Q6ZWA6, Q8IZH3	Gene names	MMTAG2, C1orf35
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 (hMMTAG2).

MYH11_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.014743 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	1806	Shared Neighborhood Hits	21
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NEST_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.028664 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	1305	Shared Neighborhood Hits	23
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PAX8_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.009363 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q06710, Q09155, Q16337, Q16338, Q16339, Q96J49	Gene names	PAX8
Domain Architecture
Description	Paired box protein Pax-8.

PCLO_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.009348 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	2275	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NOP14_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.058853 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	573	Shared Neighborhood Hits	13
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

Hits sorted by NC score

IPP4_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.1125e-93 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	O14990, Q5H958	Gene names	PPP1R2P9
Domain Architecture	No domain graphic available
Description	Type-1 protein phosphatase inhibitor 4 (I-4) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9).

IPP2_HUMAN
NC score	0.883199 (rank : 2)	θ value	3.3877e-31 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P41236	Gene names	PPP1R2, IPP2
Domain Architecture
Description	Protein phosphatase inhibitor 2 (IPP-2).

IPP2_MOUSE
NC score	0.869095 (rank : 3)	θ value	5.77852e-31 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

IF31_MOUSE
NC score	0.123974 (rank : 4)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q66JS6, Q8BUW6	Gene names	Eif3s1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha).

IF31_HUMAN
NC score	0.122530 (rank : 5)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

NOP14_HUMAN
NC score	0.058853 (rank : 6)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	39	Target Neighborhood Hits	573	Shared Neighborhood Hits	13
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CSTN1_HUMAN
NC score	0.058109 (rank : 7)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	O94985	Gene names	CLSTN1, CS1, KIAA0911
Domain Architecture	No domain graphic available
Description	Calsyntenin-1 precursor.

CSTN1_MOUSE
NC score	0.051937 (rank : 8)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPL2	Gene names	Clstn1, Cs1, Cstn1
Domain Architecture
Description	Calsyntenin-1 precursor.

RN168_HUMAN
NC score	0.051224 (rank : 9)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	370	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

CCD96_HUMAN
NC score	0.048833 (rank : 10)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	595	Shared Neighborhood Hits	13
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

RN168_MOUSE
NC score	0.042045 (rank : 11)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	440	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

FAM9A_HUMAN
NC score	0.037770 (rank : 12)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	138	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

SMCE1_MOUSE
NC score	0.037088 (rank : 13)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

AN32B_MOUSE
NC score	0.036818 (rank : 14)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

CEP35_HUMAN
NC score	0.035475 (rank : 15)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	811	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

KI21A_MOUSE
NC score	0.033974 (rank : 16)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	1317	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

GSDM1_MOUSE
NC score	0.031519 (rank : 17)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EST1	Gene names	Gsdm1, Gsdm
Domain Architecture	No domain graphic available
Description	Gasdermin.

TRHY_HUMAN
NC score	0.030971 (rank : 18)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	1385	Shared Neighborhood Hits	15
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

WRN_HUMAN
NC score	0.029288 (rank : 19)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

PESC_MOUSE
NC score	0.028903 (rank : 20)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQ61, Q542F0	Gene names	Pes1
Domain Architecture
Description	Pescadillo homolog 1.

NEST_HUMAN
NC score	0.028664 (rank : 21)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	1305	Shared Neighborhood Hits	23
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CALD1_HUMAN
NC score	0.026454 (rank : 22)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	959	Shared Neighborhood Hits	13
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CROCC_MOUSE
NC score	0.024845 (rank : 23)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	1460	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

A4_MOUSE
NC score	0.023582 (rank : 24)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	275	Shared Neighborhood Hits	8
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

MMTA2_HUMAN
NC score	0.023410 (rank : 25)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BU76, Q6P5Y0, Q6ZTZ6, Q6ZWA6, Q8IZH3	Gene names	MMTAG2, C1orf35
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 (hMMTAG2).

WASF2_HUMAN
NC score	0.022370 (rank : 26)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	280	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

MY18A_MOUSE
NC score	0.022249 (rank : 27)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	1989	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

WASF2_MOUSE
NC score	0.022085 (rank : 28)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	315	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

CCD82_HUMAN
NC score	0.020954 (rank : 29)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

CS007_HUMAN
NC score	0.020756 (rank : 30)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	401	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

M4K4_MOUSE
NC score	0.018495 (rank : 31)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	1560	Shared Neighborhood Hits	14
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.018115 (rank : 32)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	1589	Shared Neighborhood Hits	14
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MTMR7_HUMAN
NC score	0.016542 (rank : 33)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MDC1_MOUSE
NC score	0.014834 (rank : 34)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	998	Shared Neighborhood Hits	12
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MYH11_HUMAN
NC score	0.014743 (rank : 35)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	1806	Shared Neighborhood Hits	21
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

ROCK1_HUMAN
NC score	0.013474 (rank : 36)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	2000	Shared Neighborhood Hits	16
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

LYST_MOUSE
NC score	0.012615 (rank : 37)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	286	Shared Neighborhood Hits	5
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

PAX8_HUMAN
NC score	0.009363 (rank : 38)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q06710, Q09155, Q16337, Q16338, Q16339, Q96J49	Gene names	PAX8
Domain Architecture
Description	Paired box protein Pax-8.

PCLO_MOUSE
NC score	0.009348 (rank : 39)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	2275	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GP101_HUMAN
NC score	0.002481 (rank : 40)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	913	Shared Neighborhood Hits	3
SwissProt Accessions	Q96P66, Q8NG93	Gene names	GPR101
Domain Architecture
Description	Probable G-protein coupled receptor 101.