Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : LPIN3_HUMAN

For an explanation of this page, click here

LPIN3_HUMAN
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LPIN1_HUMAN
θ value	0 (rank : 1)	NC score	0.972543 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q14693	Gene names	LPIN1, KIAA0188
Domain Architecture
Description	Lipin-1.

LPIN1_MOUSE
θ value	0 (rank : 2)	NC score	0.960386 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZP3, Q9CQI2, Q9JLG6	Gene names	Lpin1, Fld
Domain Architecture
Description	Lipin-1 (Fatty liver dystrophy protein).

LPIN2_HUMAN
θ value	0 (rank : 3)	NC score	0.965992 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

LPIN2_MOUSE
θ value	0 (rank : 4)	NC score	0.973570 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PI5, Q8C357, Q8C7I8, Q8CC85, Q8CHR7	Gene names	Lpin2
Domain Architecture
Description	Lipin-2.

LPIN3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

LPIN3_MOUSE
θ value	0 (rank : 6)	NC score	0.986927 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

WNK4_MOUSE
θ value	0.00869519 (rank : 7)	NC score	0.012420 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	961	Shared Neighborhood Hits	12
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

PTPR2_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.015189 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	120	Shared Neighborhood Hits	2
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PER3_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.027831 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	479	Shared Neighborhood Hits	17
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CTND2_MOUSE
θ value	0.163984 (rank : 10)	NC score	0.029959 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

DDX51_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.014561 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

PKHA6_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.026914 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	591	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

BNIPL_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.023338 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

CTND2_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.027260 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	333	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PAK4_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.004873 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	1098	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

DREB_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.022885 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	450	Shared Neighborhood Hits	7
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GTSE1_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.032756 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

IWS1_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.044305 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	1241	Shared Neighborhood Hits	27
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TOIP2_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.029341 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

SSH2_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.014981 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

CLCN1_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.012936 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

MAGAA_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.010359 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	P43363	Gene names	MAGEA10, MAGE10
Domain Architecture
Description	Melanoma-associated antigen 10 (MAGE-10 antigen).

NBN_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.023966 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

NFH_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.012509 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	2247	Shared Neighborhood Hits	42
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RGS3_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.018446 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	1621	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SAPS1_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.017971 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	704	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

AATK_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.005383 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	942	Shared Neighborhood Hits	16
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

AUXI_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.017110 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

BCAS1_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.028750 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

IWS1_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.034682 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	1258	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TAF3_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.020021 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	568	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ZBTB5_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.003334 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	801	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).

CCDC9_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.033747 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

NSD1_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.014831 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	472	Shared Neighborhood Hits	13
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

AF1Q_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.073847 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q13015	Gene names	MLLT11, AF1Q
Domain Architecture	No domain graphic available
Description	Protein AF1q.

AF1Q_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.073646 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P97783	Gene names	Mllt11, Af1q
Domain Architecture	No domain graphic available
Description	Protein AF1q.

CUTL2_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.012117 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DEND_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.021199 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

ENL_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.044954 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	305	Shared Neighborhood Hits	15
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

IL3RB_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.019139 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

RP1L1_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.026728 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	1072	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SNRK_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.003766 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	855	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

ZHX3_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.030835 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4I2, O43145	Gene names	ZHX3, KIAA0395, TIX1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

OBSCN_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.003953 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	1931	Shared Neighborhood Hits	21
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OGFR_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.015218 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	584	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SNRK_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.003574 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	849	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDU5, Q91WX6	Gene names	Snrk
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

SYMM_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.016396 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

TAD3L_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.024333 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

TAD3L_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.024421 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

ZBT7B_HUMAN
θ value	3.0926 (rank : 50)	NC score	-0.000034 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	796	Shared Neighborhood Hits	6
SwissProt Accessions	O15156, Q68DR2, Q96EP2	Gene names	ZBTB7B, ZBTB15, ZFP67
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 7B (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein Th-POK) (T-helper-inducing POZ/Krueppel-like factor) (Krueppel-related zinc finger protein cKrox) (hcKrox) (Zinc finger and BTB domain-containing protein 15).

ANR47_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.007095 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

CI040_MOUSE
θ value	4.03905 (rank : 52)	NC score	0.031304 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

GRIN1_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.016601 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	681	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

IRF7_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.011767 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

MOCOS_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.015312 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EN8, Q53GP5, Q8N3A4, Q9NWM7	Gene names	MOCOS
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS) (HMCS).

PK1L1_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.016229 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

RFFL_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.022366 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

SKP2_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.012846 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

TARA_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.019808 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	1626	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

VAPA_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.018915 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV55, Q3TJM1, Q9QY77	Gene names	Vapa, Vap33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

WIPI3_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.019542 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q5MNZ6, O95328, Q6IBN2	Gene names	WDR45L, WIPI3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein) (WIPI49-like protein).

CI040_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.072871 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXQ3, Q9NWD3	Gene names	C9orf40
Domain Architecture	No domain graphic available
Description	Protein C9orf40.

DPOLN_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.012783 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5Q5, Q4TTW4, Q6ZNF4	Gene names	POLN
Domain Architecture	No domain graphic available
Description	DNA polymerase nu (EC 2.7.7.7).

EPAS1_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.007396 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HCN4_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.007906 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

IF4G1_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.012004 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	534	Shared Neighborhood Hits	19
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PGCA_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.005637 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	643	Shared Neighborhood Hits	13
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PITM3_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.019409 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ71, Q59GH9, Q9NPQ4	Gene names	PITPNM3, NIR1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

PITM3_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.018734 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

RIN3_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.015186 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

TMEPA_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.019146 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

VAPA_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.017761 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0L0, O75453, Q5U0E7, Q9UBZ2	Gene names	VAPA, VAP33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

CF146_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.013486 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXS0, Q5JYK1	Gene names	C6orf146
Domain Architecture	No domain graphic available
Description	Protein C6orf146.

IP3KC_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.012693 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

MAST2_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.005949 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	1189	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NOB1_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.065166 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BW10, Q7TPR3, Q9CRD7	Gene names	Nob1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1.

PP4R1_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.024550 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.023826 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

RAI14_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.001296 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	1505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TF3C2_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.011590 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TMEPA_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.017839 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

AHI1_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.002607 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	496	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

CR001_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.014259 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

FOG1_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.002198 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	981	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HCLS1_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.007446 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	358	Shared Neighborhood Hits	9
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

NKX31_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.004115 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	331	Shared Neighborhood Hits	7
SwissProt Accessions	Q99801, O15465, Q9H2P4, Q9H2P5, Q9H2P6, Q9H2P7, Q9HBG0	Gene names	NKX3-1, NKX3.1, NKX3A
Domain Architecture
Description	Homeobox protein Nkx-3.1.

NOB1_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.058612 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULX3, Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0	Gene names	NOB1, ART4, NOB1P, PSMD8BP1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1 (Protein ART-4) (Phosphorylation regulatory protein HP-10).

PCLO_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.008431 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	2275	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PHX2B_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.003488 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	407	Shared Neighborhood Hits	10
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.003488 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	407	Shared Neighborhood Hits	10
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

R3HD2_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.008831 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	397	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

ZHX3_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.027506 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	321	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

Hits sorted by NC score

LPIN3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

LPIN3_MOUSE
NC score	0.986927 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

LPIN2_MOUSE
NC score	0.973570 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PI5, Q8C357, Q8C7I8, Q8CC85, Q8CHR7	Gene names	Lpin2
Domain Architecture
Description	Lipin-2.

LPIN1_HUMAN
NC score	0.972543 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q14693	Gene names	LPIN1, KIAA0188
Domain Architecture
Description	Lipin-1.

LPIN2_HUMAN
NC score	0.965992 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

LPIN1_MOUSE
NC score	0.960386 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZP3, Q9CQI2, Q9JLG6	Gene names	Lpin1, Fld
Domain Architecture
Description	Lipin-1 (Fatty liver dystrophy protein).

AF1Q_HUMAN
NC score	0.073847 (rank : 7)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q13015	Gene names	MLLT11, AF1Q
Domain Architecture	No domain graphic available
Description	Protein AF1q.

AF1Q_MOUSE
NC score	0.073646 (rank : 8)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P97783	Gene names	Mllt11, Af1q
Domain Architecture	No domain graphic available
Description	Protein AF1q.

CI040_HUMAN
NC score	0.072871 (rank : 9)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXQ3, Q9NWD3	Gene names	C9orf40
Domain Architecture	No domain graphic available
Description	Protein C9orf40.

NOB1_MOUSE
NC score	0.065166 (rank : 10)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BW10, Q7TPR3, Q9CRD7	Gene names	Nob1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1.

NOB1_HUMAN
NC score	0.058612 (rank : 11)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULX3, Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0	Gene names	NOB1, ART4, NOB1P, PSMD8BP1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1 (Protein ART-4) (Phosphorylation regulatory protein HP-10).

ENL_HUMAN
NC score	0.044954 (rank : 12)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	305	Shared Neighborhood Hits	15
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

IWS1_HUMAN
NC score	0.044305 (rank : 13)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	1241	Shared Neighborhood Hits	27
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.034682 (rank : 14)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	1258	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CCDC9_HUMAN
NC score	0.033747 (rank : 15)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

GTSE1_HUMAN
NC score	0.032756 (rank : 16)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

CI040_MOUSE
NC score	0.031304 (rank : 17)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

ZHX3_HUMAN
NC score	0.030835 (rank : 18)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4I2, O43145	Gene names	ZHX3, KIAA0395, TIX1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

CTND2_MOUSE
NC score	0.029959 (rank : 19)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

TOIP2_MOUSE
NC score	0.029341 (rank : 20)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

BCAS1_HUMAN
NC score	0.028750 (rank : 21)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

PER3_HUMAN
NC score	0.027831 (rank : 22)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	479	Shared Neighborhood Hits	17
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

ZHX3_MOUSE
NC score	0.027506 (rank : 23)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	321	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

CTND2_HUMAN
NC score	0.027260 (rank : 24)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	333	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PKHA6_MOUSE
NC score	0.026914 (rank : 25)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	591	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RP1L1_HUMAN
NC score	0.026728 (rank : 26)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	1072	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

PP4R1_HUMAN
NC score	0.024550 (rank : 27)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

TAD3L_MOUSE
NC score	0.024421 (rank : 28)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TAD3L_HUMAN
NC score	0.024333 (rank : 29)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

NBN_HUMAN
NC score	0.023966 (rank : 30)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

PP4R1_MOUSE
NC score	0.023826 (rank : 31)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

BNIPL_HUMAN
NC score	0.023338 (rank : 32)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

DREB_HUMAN
NC score	0.022885 (rank : 33)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	450	Shared Neighborhood Hits	7
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

RFFL_HUMAN
NC score	0.022366 (rank : 34)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

DEND_HUMAN
NC score	0.021199 (rank : 35)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

TAF3_HUMAN
NC score	0.020021 (rank : 36)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	568	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TARA_HUMAN
NC score	0.019808 (rank : 37)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	1626	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WIPI3_HUMAN
NC score	0.019542 (rank : 38)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q5MNZ6, O95328, Q6IBN2	Gene names	WDR45L, WIPI3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein) (WIPI49-like protein).

PITM3_HUMAN
NC score	0.019409 (rank : 39)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ71, Q59GH9, Q9NPQ4	Gene names	PITPNM3, NIR1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

TMEPA_MOUSE
NC score	0.019146 (rank : 40)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

IL3RB_HUMAN
NC score	0.019139 (rank : 41)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

VAPA_MOUSE
NC score	0.018915 (rank : 42)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV55, Q3TJM1, Q9QY77	Gene names	Vapa, Vap33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

PITM3_MOUSE
NC score	0.018734 (rank : 43)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

RGS3_MOUSE
NC score	0.018446 (rank : 44)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	1621	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SAPS1_HUMAN
NC score	0.017971 (rank : 45)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	704	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TMEPA_HUMAN
NC score	0.017839 (rank : 46)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

VAPA_HUMAN
NC score	0.017761 (rank : 47)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0L0, O75453, Q5U0E7, Q9UBZ2	Gene names	VAPA, VAP33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

AUXI_HUMAN
NC score	0.017110 (rank : 48)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

GRIN1_HUMAN
NC score	0.016601 (rank : 49)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	681	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SYMM_HUMAN
NC score	0.016396 (rank : 50)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

PK1L1_HUMAN
NC score	0.016229 (rank : 51)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

MOCOS_HUMAN
NC score	0.015312 (rank : 52)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EN8, Q53GP5, Q8N3A4, Q9NWM7	Gene names	MOCOS
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS) (HMCS).

OGFR_MOUSE
NC score	0.015218 (rank : 53)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	584	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PTPR2_MOUSE
NC score	0.015189 (rank : 54)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	120	Shared Neighborhood Hits	2
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

RIN3_HUMAN
NC score	0.015186 (rank : 55)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SSH2_HUMAN
NC score	0.014981 (rank : 56)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

NSD1_MOUSE
NC score	0.014831 (rank : 57)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	472	Shared Neighborhood Hits	13
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

DDX51_MOUSE
NC score	0.014561 (rank : 58)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

CR001_HUMAN
NC score	0.014259 (rank : 59)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CF146_HUMAN
NC score	0.013486 (rank : 60)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXS0, Q5JYK1	Gene names	C6orf146
Domain Architecture	No domain graphic available
Description	Protein C6orf146.

CLCN1_HUMAN
NC score	0.012936 (rank : 61)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

SKP2_MOUSE
NC score	0.012846 (rank : 62)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

DPOLN_HUMAN
NC score	0.012783 (rank : 63)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5Q5, Q4TTW4, Q6ZNF4	Gene names	POLN
Domain Architecture	No domain graphic available
Description	DNA polymerase nu (EC 2.7.7.7).

IP3KC_HUMAN
NC score	0.012693 (rank : 64)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

NFH_MOUSE
NC score	0.012509 (rank : 65)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	2247	Shared Neighborhood Hits	42
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

WNK4_MOUSE
NC score	0.012420 (rank : 66)	θ value	0.00869519 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	961	Shared Neighborhood Hits	12
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CUTL2_HUMAN
NC score	0.012117 (rank : 67)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

IF4G1_MOUSE
NC score	0.012004 (rank : 68)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	534	Shared Neighborhood Hits	19
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IRF7_HUMAN
NC score	0.011767 (rank : 69)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

TF3C2_MOUSE
NC score	0.011590 (rank : 70)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

MAGAA_HUMAN
NC score	0.010359 (rank : 71)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	P43363	Gene names	MAGEA10, MAGE10
Domain Architecture
Description	Melanoma-associated antigen 10 (MAGE-10 antigen).

R3HD2_MOUSE
NC score	0.008831 (rank : 72)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	397	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

PCLO_MOUSE
NC score	0.008431 (rank : 73)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	2275	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

HCN4_HUMAN
NC score	0.007906 (rank : 74)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCLS1_HUMAN
NC score	0.007446 (rank : 75)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	358	Shared Neighborhood Hits	9
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

EPAS1_HUMAN
NC score	0.007396 (rank : 76)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

ANR47_HUMAN
NC score	0.007095 (rank : 77)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

MAST2_HUMAN
NC score	0.005949 (rank : 78)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	1189	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PGCA_MOUSE
NC score	0.005637 (rank : 79)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	643	Shared Neighborhood Hits	13
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

AATK_MOUSE
NC score	0.005383 (rank : 80)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	942	Shared Neighborhood Hits	16
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

PAK4_MOUSE
NC score	0.004873 (rank : 81)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	1098	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

NKX31_HUMAN
NC score	0.004115 (rank : 82)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	331	Shared Neighborhood Hits	7
SwissProt Accessions	Q99801, O15465, Q9H2P4, Q9H2P5, Q9H2P6, Q9H2P7, Q9HBG0	Gene names	NKX3-1, NKX3.1, NKX3A
Domain Architecture
Description	Homeobox protein Nkx-3.1.

OBSCN_HUMAN
NC score	0.003953 (rank : 83)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	1931	Shared Neighborhood Hits	21
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SNRK_HUMAN
NC score	0.003766 (rank : 84)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	855	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

SNRK_MOUSE
NC score	0.003574 (rank : 85)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	849	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDU5, Q91WX6	Gene names	Snrk
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

PHX2B_HUMAN
NC score	0.003488 (rank : 86)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	407	Shared Neighborhood Hits	10
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
NC score	0.003488 (rank : 87)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	407	Shared Neighborhood Hits	10
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

ZBTB5_MOUSE
NC score	0.003334 (rank : 88)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	801	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).

AHI1_MOUSE
NC score	0.002607 (rank : 89)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	496	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

FOG1_HUMAN
NC score	0.002198 (rank : 90)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	981	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

RAI14_MOUSE
NC score	0.001296 (rank : 91)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	1505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ZBT7B_HUMAN
NC score	-0.000034 (rank : 92)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	796	Shared Neighborhood Hits	6
SwissProt Accessions	O15156, Q68DR2, Q96EP2	Gene names	ZBTB7B, ZBTB15, ZFP67
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 7B (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein Th-POK) (T-helper-inducing POZ/Krueppel-like factor) (Krueppel-related zinc finger protein cKrox) (hcKrox) (Zinc finger and BTB domain-containing protein 15).