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Network neighborhood for query Sequence : TMEPA_HUMAN

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TMEPA_HUMAN
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TMEPA_HUMAN
θ value	5.94893e-161 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

TMEPA_MOUSE
θ value	1.29561e-123 (rank : 2)	NC score	0.987021 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

CR001_HUMAN
θ value	3.56943e-81 (rank : 3)	NC score	0.886250 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
θ value	1.14825e-79 (rank : 4)	NC score	0.887366 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

CRTC1_HUMAN
θ value	0.00665767 (rank : 5)	NC score	0.134398 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ATN1_HUMAN
θ value	0.0563607 (rank : 6)	NC score	0.084801 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	676	Shared Neighborhood Hits	17
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CRTC1_MOUSE
θ value	0.0563607 (rank : 7)	NC score	0.112518 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	230	Shared Neighborhood Hits	6
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CPSF7_HUMAN
θ value	0.0961366 (rank : 8)	NC score	0.104507 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

GSCR1_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.074772 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	674	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CPSF7_MOUSE
θ value	0.279714 (rank : 10)	NC score	0.095740 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

CAC1B_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.019655 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	257	Shared Neighborhood Hits	6
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

GAB1_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.076973 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	233	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PDC6I_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.072561 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

TULP4_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.064009 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	426	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

PDC6I_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.068181 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

TULP4_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.057535 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TROAP_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.057833 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

BL1S3_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.056619 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5M8, Q8C6R4, Q8R0Z3	Gene names	Bloc1s3, Blos3, Rp
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (Reduced pigmentation protein) (BLOC subunit 3).

CASC3_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.050839 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	333	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

NFAC4_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.025623 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

CELR2_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.009680 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	657	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

IL3RB_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.026662 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	355	Shared Neighborhood Hits	15
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

MAGE1_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.019368 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	1389	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SMR3B_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.055229 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

CNOT3_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.022889 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	425	Shared Neighborhood Hits	8
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

PDZD8_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.060684 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	185	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

AMOL2_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.010388 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	591	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

ANKZ1_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.020160 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

BSN_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.024344 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	1537	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

FOXN1_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.015194 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

NCOR2_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.016381 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	870	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SFPQ_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.015881 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	986	Shared Neighborhood Hits	16
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SHAN1_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.012314 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	1041	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SYNJ2_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.013102 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

HES1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.029236 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

PHC2_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.023302 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	388	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

FRS2_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.012265 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C180	Gene names	Frs2, Frs2a
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT) (FRS2 alpha).

GNAS3_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.058195 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

IRF5_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.008945 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

LPIN3_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.017839 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

PDZD2_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.015756 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	772	Shared Neighborhood Hits	15
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

ZN516_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.004160 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	1197	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CELR2_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.007117 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	584	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

KRHB2_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.003625 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSB4	Gene names	KRTHB2
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

TCGAP_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.012662 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	872	Shared Neighborhood Hits	20
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TITIN_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.000411 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	2923	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

Hits sorted by NC score

TMEPA_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.94893e-161 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

TMEPA_MOUSE
NC score	0.987021 (rank : 2)	θ value	1.29561e-123 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

CR001_MOUSE
NC score	0.887366 (rank : 3)	θ value	1.14825e-79 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

CR001_HUMAN
NC score	0.886250 (rank : 4)	θ value	3.56943e-81 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CRTC1_HUMAN
NC score	0.134398 (rank : 5)	θ value	0.00665767 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CRTC1_MOUSE
NC score	0.112518 (rank : 6)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	230	Shared Neighborhood Hits	6
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CPSF7_HUMAN
NC score	0.104507 (rank : 7)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

CPSF7_MOUSE
NC score	0.095740 (rank : 8)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

ATN1_HUMAN
NC score	0.084801 (rank : 9)	θ value	0.0563607 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	676	Shared Neighborhood Hits	17
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

GAB1_MOUSE
NC score	0.076973 (rank : 10)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	233	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GSCR1_HUMAN
NC score	0.074772 (rank : 11)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	674	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PDC6I_HUMAN
NC score	0.072561 (rank : 12)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDC6I_MOUSE
NC score	0.068181 (rank : 13)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

TULP4_HUMAN
NC score	0.064009 (rank : 14)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	426	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

PDZD8_HUMAN
NC score	0.060684 (rank : 15)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	185	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

GNAS3_MOUSE
NC score	0.058195 (rank : 16)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

TROAP_HUMAN
NC score	0.057833 (rank : 17)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TULP4_MOUSE
NC score	0.057535 (rank : 18)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

BL1S3_MOUSE
NC score	0.056619 (rank : 19)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5M8, Q8C6R4, Q8R0Z3	Gene names	Bloc1s3, Blos3, Rp
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (Reduced pigmentation protein) (BLOC subunit 3).

SMR3B_HUMAN
NC score	0.055229 (rank : 20)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

CASC3_MOUSE
NC score	0.050839 (rank : 21)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	333	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

HES1_HUMAN
NC score	0.029236 (rank : 22)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

IL3RB_MOUSE
NC score	0.026662 (rank : 23)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	355	Shared Neighborhood Hits	15
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

NFAC4_HUMAN
NC score	0.025623 (rank : 24)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

BSN_HUMAN
NC score	0.024344 (rank : 25)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	1537	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PHC2_HUMAN
NC score	0.023302 (rank : 26)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	388	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

CNOT3_HUMAN
NC score	0.022889 (rank : 27)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	425	Shared Neighborhood Hits	8
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ANKZ1_MOUSE
NC score	0.020160 (rank : 28)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CAC1B_HUMAN
NC score	0.019655 (rank : 29)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	257	Shared Neighborhood Hits	6
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

MAGE1_HUMAN
NC score	0.019368 (rank : 30)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	1389	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

LPIN3_HUMAN
NC score	0.017839 (rank : 31)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

NCOR2_HUMAN
NC score	0.016381 (rank : 32)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	870	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SFPQ_HUMAN
NC score	0.015881 (rank : 33)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	986	Shared Neighborhood Hits	16
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

PDZD2_HUMAN
NC score	0.015756 (rank : 34)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	772	Shared Neighborhood Hits	15
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

FOXN1_HUMAN
NC score	0.015194 (rank : 35)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

SYNJ2_HUMAN
NC score	0.013102 (rank : 36)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

TCGAP_HUMAN
NC score	0.012662 (rank : 37)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	872	Shared Neighborhood Hits	20
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SHAN1_HUMAN
NC score	0.012314 (rank : 38)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	1041	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

FRS2_MOUSE
NC score	0.012265 (rank : 39)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C180	Gene names	Frs2, Frs2a
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT) (FRS2 alpha).

AMOL2_MOUSE
NC score	0.010388 (rank : 40)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	591	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

CELR2_HUMAN
NC score	0.009680 (rank : 41)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	657	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

IRF5_MOUSE
NC score	0.008945 (rank : 42)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

CELR2_MOUSE
NC score	0.007117 (rank : 43)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	584	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

ZN516_MOUSE
NC score	0.004160 (rank : 44)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	1197	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

KRHB2_HUMAN
NC score	0.003625 (rank : 45)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSB4	Gene names	KRTHB2
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

TITIN_HUMAN
NC score	0.000411 (rank : 46)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	2923	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).