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Network neighborhood for query Sequence : BPL1_MOUSE

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BPL1_MOUSE
SwissProt Accessions	Q920N2	Gene names	Hlcs
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BPL1_HUMAN
θ value	0 (rank : 1)	NC score	0.991408 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P50747, Q99451	Gene names	HLCS
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].

BPL1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q920N2	Gene names	Hlcs
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].

GFI1_MOUSE
θ value	0.62314 (rank : 3)	NC score	0.005329 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	736	Shared Neighborhood Hits	4
SwissProt Accessions	P70338, O09063	Gene names	Gfi1, Gfi-1
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

GSCR1_HUMAN
θ value	0.62314 (rank : 4)	NC score	0.035763 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	674	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SCAR3_HUMAN
θ value	5.27518 (rank : 5)	NC score	0.012087 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

ZEP2_HUMAN
θ value	5.27518 (rank : 6)	NC score	0.006885 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	937	Shared Neighborhood Hits	5
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

MX2_MOUSE
θ value	6.88961 (rank : 7)	NC score	0.014638 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

ADA17_HUMAN
θ value	8.99809 (rank : 8)	NC score	0.007594 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

CP27A_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.005182 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q02318, Q6LDB4, Q86YQ6	Gene names	CYP27A1, CYP27
Domain Architecture
Description	Cytochrome P450 27, mitochondrial precursor (EC 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27- hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3- alpha,7-alpha,12-alpha-triol 27-hydroxylase).

FBX46_MOUSE
θ value	8.99809 (rank : 10)	NC score	0.013126 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

MX1_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.013669 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

PARM1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.018383 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

SP8_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.002753 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	710	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMJ8, Q8BWA3	Gene names	Sp8
Domain Architecture	No domain graphic available
Description	Transcription factor Sp8.

TP53B_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.010751 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	644	Shared Neighborhood Hits	4
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZIMP7_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.009212 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	566	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

Hits sorted by NC score

BPL1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q920N2	Gene names	Hlcs
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].

BPL1_HUMAN
NC score	0.991408 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P50747, Q99451	Gene names	HLCS
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].

GSCR1_HUMAN
NC score	0.035763 (rank : 3)	θ value	0.62314 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	674	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PARM1_HUMAN
NC score	0.018383 (rank : 4)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

MX2_MOUSE
NC score	0.014638 (rank : 5)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_MOUSE
NC score	0.013669 (rank : 6)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

FBX46_MOUSE
NC score	0.013126 (rank : 7)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

SCAR3_HUMAN
NC score	0.012087 (rank : 8)	θ value	5.27518 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

TP53B_MOUSE
NC score	0.010751 (rank : 9)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	644	Shared Neighborhood Hits	4
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZIMP7_MOUSE
NC score	0.009212 (rank : 10)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	566	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ADA17_HUMAN
NC score	0.007594 (rank : 11)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ZEP2_HUMAN
NC score	0.006885 (rank : 12)	θ value	5.27518 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	937	Shared Neighborhood Hits	5
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

GFI1_MOUSE
NC score	0.005329 (rank : 13)	θ value	0.62314 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	736	Shared Neighborhood Hits	4
SwissProt Accessions	P70338, O09063	Gene names	Gfi1, Gfi-1
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

CP27A_HUMAN
NC score	0.005182 (rank : 14)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q02318, Q6LDB4, Q86YQ6	Gene names	CYP27A1, CYP27
Domain Architecture
Description	Cytochrome P450 27, mitochondrial precursor (EC 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27- hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3- alpha,7-alpha,12-alpha-triol 27-hydroxylase).

SP8_MOUSE
NC score	0.002753 (rank : 15)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	710	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMJ8, Q8BWA3	Gene names	Sp8
Domain Architecture	No domain graphic available
Description	Transcription factor Sp8.