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Network neighborhood for query Sequence : FBX16_HUMAN

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FBX16_HUMAN
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBX16_HUMAN
θ value	3.37019e-164 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FBX16_MOUSE
θ value	2.59848e-140 (rank : 2)	NC score	0.986554 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	39	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FBXW7_HUMAN
θ value	1.9326e-10 (rank : 3)	NC score	0.221006 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	433	Shared Neighborhood Hits	46
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	1.9326e-10 (rank : 4)	NC score	0.221649 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	365	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXW2_HUMAN
θ value	3.19293e-05 (rank : 5)	NC score	0.217563 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	260	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

FBXL5_HUMAN
θ value	4.1701e-05 (rank : 6)	NC score	0.355999 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	111	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FBXL5_MOUSE
θ value	4.1701e-05 (rank : 7)	NC score	0.359139 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBW1B_HUMAN
θ value	0.000121331 (rank : 8)	NC score	0.165772 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBX2_MOUSE
θ value	0.000461057 (rank : 9)	NC score	0.302673 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q80UW2, Q8R0D2	Gene names	Fbxo2, Fbx2
Domain Architecture	No domain graphic available
Description	F-box only protein 2.

FBXW8_HUMAN
θ value	0.000602161 (rank : 10)	NC score	0.359280 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	192	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBXL7_HUMAN
θ value	0.000786445 (rank : 11)	NC score	0.290255 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	91	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FBX27_HUMAN
θ value	0.00175202 (rank : 12)	NC score	0.310409 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	39	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

FBW1A_HUMAN
θ value	0.00228821 (rank : 13)	NC score	0.159125 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	329	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FXL20_HUMAN
θ value	0.00228821 (rank : 14)	NC score	0.275563 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
θ value	0.00228821 (rank : 15)	NC score	0.275751 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	78	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FBXL2_HUMAN
θ value	0.00298849 (rank : 16)	NC score	0.266905 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBX6_HUMAN
θ value	0.00390308 (rank : 17)	NC score	0.274207 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRD1, Q9UKT3	Gene names	FBXO6, FBG2, FBX6
Domain Architecture
Description	F-box only protein 6 (F-box/G-domain protein 2).

FBXL2_MOUSE
θ value	0.00390308 (rank : 18)	NC score	0.265099 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXW2_MOUSE
θ value	0.00390308 (rank : 19)	NC score	0.195003 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	249	Shared Neighborhood Hits	14
SwissProt Accessions	Q60584	Gene names	Fbxw2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

FBXW8_MOUSE
θ value	0.00390308 (rank : 20)	NC score	0.335308 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	162	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FBW12_HUMAN
θ value	0.00509761 (rank : 21)	NC score	0.247775 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

FBX2_HUMAN
θ value	0.0193708 (rank : 22)	NC score	0.274890 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK22, Q6FGJ7, Q8TB29, Q9UKC6	Gene names	FBXO2, FBX2
Domain Architecture
Description	F-box only protein 2.

FBX17_MOUSE
θ value	0.0252991 (rank : 23)	NC score	0.264628 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZM8	Gene names	Fbxo17, Fbx17, Fbxo26
Domain Architecture
Description	F-box only protein 17 (F-box only protein 26).

FBX4_HUMAN
θ value	0.0252991 (rank : 24)	NC score	0.245540 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKT5, Q68CU8, Q86VT8, Q9UK98	Gene names	FBXO4, FBX4
Domain Architecture
Description	F-box only protein 4.

FBX27_MOUSE
θ value	0.0330416 (rank : 25)	NC score	0.278683 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q6DIA9, Q3TYP0, Q8BKF7	Gene names	Fbxo27
Domain Architecture	No domain graphic available
Description	F-box only protein 27.

FBX4_MOUSE
θ value	0.0563607 (rank : 26)	NC score	0.230750 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CHQ0, Q99JG8	Gene names	Fbxo4, Fbx4
Domain Architecture	No domain graphic available
Description	F-box only protein 4.

FBX17_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.251544 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q96EF6, Q96LQ4	Gene names	FBXO17, FBG4, FBX17, FBX26, FBXO26
Domain Architecture
Description	F-box only protein 17 (F-box only protein 26).

FBX3_HUMAN
θ value	0.0736092 (rank : 28)	NC score	0.196291 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UK99, Q9NUX2	Gene names	FBXO3, FBX3
Domain Architecture
Description	F-box only protein 3.

FBX44_HUMAN
θ value	0.0961366 (rank : 29)	NC score	0.250658 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H4M3, Q5TGX2, Q5TGX4, Q5TGX5, Q68DJ9, Q8WWY2	Gene names	FBXO44, FBG3, FBX30, FBX44, FBX6A, FBXO6A
Domain Architecture
Description	F-box only protein 44 (F-box protein FBX30) (F-box/G-domain protein 3).

FXL19_HUMAN
θ value	0.0961366 (rank : 30)	NC score	0.151293 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	147	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
θ value	0.0961366 (rank : 31)	NC score	0.149867 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FBX44_MOUSE
θ value	0.125558 (rank : 32)	NC score	0.250784 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BK26, Q8K128	Gene names	Fbxo44, Fbxo6a
Domain Architecture	No domain graphic available
Description	F-box only protein 44 (F-box only protein 6a).

FBX6_MOUSE
θ value	0.125558 (rank : 33)	NC score	0.240030 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZN4, Q3TML5	Gene names	Fbxo6, Fbxo6b
Domain Architecture	No domain graphic available
Description	F-box only protein 6 (F-box only protein 6b).

FBX11_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.188197 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FBXW4_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.160502 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

FBXW4_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.169724 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	209	Shared Neighborhood Hits	26
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

FBX3_MOUSE
θ value	0.279714 (rank : 37)	NC score	0.165290 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	35	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DC63, Q3TKB0	Gene names	Fbxo3, Fba, Fbx3
Domain Architecture
Description	F-box only protein 3.

FXL12_MOUSE
θ value	0.365318 (rank : 38)	NC score	0.215749 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL12_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.228471 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	86	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FBSP1_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.051358 (rank : 174)
Query Neighborhood Hits	51	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

FXL14_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.175779 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.176132 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FBX33_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.095366 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

FBX41_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.086501 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	475	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.082793 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	430	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FXL21_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.072451 (rank : 68)
Query Neighborhood Hits	51	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

JHD1B_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.089671 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	214	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

AGAL_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.015277 (rank : 180)
Query Neighborhood Hits	51	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P06280	Gene names	GLA
Domain Architecture
Description	Alpha-galactosidase A precursor (EC 3.2.1.22) (Melibiase) (Alpha-D- galactoside galactohydrolase) (Alpha-D-galactosidase A) (Agalsidase alfa).

FBX15_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.060836 (rank : 106)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBX31_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.086358 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

SAMD4_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.021174 (rank : 179)
Query Neighborhood Hits	51	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

AAMP_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.069174 (rank : 75)
Query Neighborhood Hits	51	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

APAF_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.056534 (rank : 125)
Query Neighborhood Hits	51	Target Neighborhood Hits	334	Shared Neighborhood Hits	9
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

APAF_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.055336 (rank : 133)
Query Neighborhood Hits	51	Target Neighborhood Hits	343	Shared Neighborhood Hits	10
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

BRWD1_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.055368 (rank : 132)
Query Neighborhood Hits	51	Target Neighborhood Hits	448	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRWD1_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.052933 (rank : 159)
Query Neighborhood Hits	51	Target Neighborhood Hits	478	Shared Neighborhood Hits	10
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CDC20_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.053197 (rank : 153)
Query Neighborhood Hits	51	Target Neighborhood Hits	329	Shared Neighborhood Hits	10
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

CDC20_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.051773 (rank : 169)
Query Neighborhood Hits	51	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

COPA_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.060678 (rank : 108)
Query Neighborhood Hits	51	Target Neighborhood Hits	297	Shared Neighborhood Hits	8
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

COPB2_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.064023 (rank : 91)
Query Neighborhood Hits	51	Target Neighborhood Hits	315	Shared Neighborhood Hits	10
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

COPB2_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.064045 (rank : 90)
Query Neighborhood Hits	51	Target Neighborhood Hits	315	Shared Neighborhood Hits	10
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

ERCC8_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.057744 (rank : 122)
Query Neighborhood Hits	51	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	Q13216, Q6FHX5, Q96GB9	Gene names	ERCC8, CKN1, CSA
Domain Architecture
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA).

ERCC8_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.057514 (rank : 123)
Query Neighborhood Hits	51	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFD5, Q3U066, Q8VDC4, Q9CWK7	Gene names	Ercc8, Ckn1, Csa
Domain Architecture	No domain graphic available
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog).

FAN_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.051623 (rank : 171)
Query Neighborhood Hits	51	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FAN_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.054227 (rank : 142)
Query Neighborhood Hits	51	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FBX10_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.050750 (rank : 175)
Query Neighborhood Hits	51	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

FBX36_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.055801 (rank : 127)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEA4, Q8WWD4	Gene names	FBXO36, FBX36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

FBX37_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.111273 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX37_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.116929 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX8_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.054328 (rank : 141)
Query Neighborhood Hits	51	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX8_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.052643 (rank : 162)
Query Neighborhood Hits	51	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBXL4_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.127618 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

FBXL6_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.089277 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	65	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FBXL6_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.080136 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

FBXW9_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.096911 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	184	Shared Neighborhood Hits	13
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

FXL13_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.138064 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	81	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.138091 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL16_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.134441 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL22_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.101873 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	40	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

GBB1_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.055066 (rank : 134)
Query Neighborhood Hits	51	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	P62873, P04697, P04901	Gene names	GNB1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB1_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.055066 (rank : 135)
Query Neighborhood Hits	51	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	P62874, P04697, P04901	Gene names	Gnb1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB3_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.054593 (rank : 137)
Query Neighborhood Hits	51	Target Neighborhood Hits	282	Shared Neighborhood Hits	10
SwissProt Accessions	P16520, Q9BQC0	Gene names	GNB3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

GBB3_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.053005 (rank : 157)
Query Neighborhood Hits	51	Target Neighborhood Hits	283	Shared Neighborhood Hits	9
SwissProt Accessions	Q61011	Gene names	Gnb3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

GBB4_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.053133 (rank : 154)
Query Neighborhood Hits	51	Target Neighborhood Hits	288	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HAV0	Gene names	GNB4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

GBB4_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.052430 (rank : 164)
Query Neighborhood Hits	51	Target Neighborhood Hits	283	Shared Neighborhood Hits	9
SwissProt Accessions	P29387, Q3TJJ1, Q8R475, Q9JHX8	Gene names	Gnb4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

GBB5_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.051620 (rank : 172)
Query Neighborhood Hits	51	Target Neighborhood Hits	299	Shared Neighborhood Hits	10
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBB5_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.051893 (rank : 167)
Query Neighborhood Hits	51	Target Neighborhood Hits	298	Shared Neighborhood Hits	10
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBLP_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.058025 (rank : 119)
Query Neighborhood Hits	51	Target Neighborhood Hits	316	Shared Neighborhood Hits	10
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.058025 (rank : 120)
Query Neighborhood Hits	51	Target Neighborhood Hits	316	Shared Neighborhood Hits	10
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

JHD1A_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.076879 (rank : 66)
Query Neighborhood Hits	51	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.074786 (rank : 67)
Query Neighborhood Hits	51	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

JHD1B_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.082934 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

KTNB1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.059487 (rank : 111)
Query Neighborhood Hits	51	Target Neighborhood Hits	349	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.059462 (rank : 112)
Query Neighborhood Hits	51	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

LIS1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.068243 (rank : 78)
Query Neighborhood Hits	51	Target Neighborhood Hits	333	Shared Neighborhood Hits	11
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.068234 (rank : 79)
Query Neighborhood Hits	51	Target Neighborhood Hits	336	Shared Neighborhood Hits	11
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LRC29_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.123885 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

MORG1_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.062937 (rank : 96)
Query Neighborhood Hits	51	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BRX9, Q53FT6	Gene names	MORG1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

MORG1_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.062894 (rank : 97)
Query Neighborhood Hits	51	Target Neighborhood Hits	281	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAJ4, Q505C2, Q8VEB7, Q99JX9, Q9D235	Gene names	Morg1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

NLE1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.059615 (rank : 110)
Query Neighborhood Hits	51	Target Neighborhood Hits	334	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

NLE1_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.058059 (rank : 118)
Query Neighborhood Hits	51	Target Neighborhood Hits	332	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

PEX7_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.061249 (rank : 105)
Query Neighborhood Hits	51	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	O00628	Gene names	PEX7, PTS2R
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

PEX7_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.061673 (rank : 104)
Query Neighborhood Hits	51	Target Neighborhood Hits	279	Shared Neighborhood Hits	9
SwissProt Accessions	P97865	Gene names	Pex7
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

PK1IP_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.066003 (rank : 88)
Query Neighborhood Hits	51	Target Neighborhood Hits	277	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

PK1IP_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.067745 (rank : 80)
Query Neighborhood Hits	51	Target Neighborhood Hits	313	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

PLAP_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.072064 (rank : 69)
Query Neighborhood Hits	51	Target Neighborhood Hits	266	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

PLAP_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.071886 (rank : 70)
Query Neighborhood Hits	51	Target Neighborhood Hits	261	Shared Neighborhood Hits	8
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

PLRG1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.070635 (rank : 73)
Query Neighborhood Hits	51	Target Neighborhood Hits	318	Shared Neighborhood Hits	10
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

PLRG1_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.071103 (rank : 72)
Query Neighborhood Hits	51	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

PRP17_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.059020 (rank : 114)
Query Neighborhood Hits	51	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

PRP17_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.059293 (rank : 113)
Query Neighborhood Hits	51	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

PRP4_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.062359 (rank : 100)
Query Neighborhood Hits	51	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

PRP4_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.062860 (rank : 98)
Query Neighborhood Hits	51	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

PWP1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.053039 (rank : 156)
Query Neighborhood Hits	51	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

PWP1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.051769 (rank : 170)
Query Neighborhood Hits	51	Target Neighborhood Hits	278	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

SCAP_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.097512 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	368	Shared Neighborhood Hits	10
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SKP2_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.132441 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

SKP2_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.121118 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

SMU1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.058555 (rank : 115)
Query Neighborhood Hits	51	Target Neighborhood Hits	311	Shared Neighborhood Hits	10
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.058555 (rank : 116)
Query Neighborhood Hits	51	Target Neighborhood Hits	311	Shared Neighborhood Hits	10
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SPG16_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.056021 (rank : 126)
Query Neighborhood Hits	51	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

SPG16_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.052843 (rank : 160)
Query Neighborhood Hits	51	Target Neighborhood Hits	377	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

TAF5L_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.051401 (rank : 173)
Query Neighborhood Hits	51	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

TAF5L_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.050686 (rank : 176)
Query Neighborhood Hits	51	Target Neighborhood Hits	337	Shared Neighborhood Hits	9
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

TAF5_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.053724 (rank : 146)
Query Neighborhood Hits	51	Target Neighborhood Hits	352	Shared Neighborhood Hits	9
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.053970 (rank : 143)
Query Neighborhood Hits	51	Target Neighborhood Hits	366	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TBL1R_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.053298 (rank : 150)
Query Neighborhood Hits	51	Target Neighborhood Hits	327	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.053251 (rank : 152)
Query Neighborhood Hits	51	Target Neighborhood Hits	329	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1X_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.053607 (rank : 148)
Query Neighborhood Hits	51	Target Neighborhood Hits	329	Shared Neighborhood Hits	8
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

TBL1Y_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.053091 (rank : 155)
Query Neighborhood Hits	51	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

TBL3_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.061676 (rank : 103)
Query Neighborhood Hits	51	Target Neighborhood Hits	286	Shared Neighborhood Hits	8
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

TBLX_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.053573 (rank : 149)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

TEP1_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.055542 (rank : 129)
Query Neighborhood Hits	51	Target Neighborhood Hits	371	Shared Neighborhood Hits	11
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

TEP1_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.055550 (rank : 128)
Query Neighborhood Hits	51	Target Neighborhood Hits	344	Shared Neighborhood Hits	11
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

TRAF7_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.081606 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	482	Shared Neighborhood Hits	9
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.081888 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	470	Shared Neighborhood Hits	9
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

U3IP2_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.066522 (rank : 86)
Query Neighborhood Hits	51	Target Neighborhood Hits	307	Shared Neighborhood Hits	8
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

U3IP2_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.068938 (rank : 76)
Query Neighborhood Hits	51	Target Neighborhood Hits	312	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

UTP15_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.055459 (rank : 130)
Query Neighborhood Hits	51	Target Neighborhood Hits	296	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

UTP15_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.057141 (rank : 124)
Query Neighborhood Hits	51	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

WD51A_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.054785 (rank : 136)
Query Neighborhood Hits	51	Target Neighborhood Hits	337	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WD51A_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.055428 (rank : 131)
Query Neighborhood Hits	51	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WD51B_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.053272 (rank : 151)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WD51B_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.052832 (rank : 161)
Query Neighborhood Hits	51	Target Neighborhood Hits	321	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WDR12_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.067263 (rank : 84)
Query Neighborhood Hits	51	Target Neighborhood Hits	300	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR12_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.069695 (rank : 74)
Query Neighborhood Hits	51	Target Neighborhood Hits	301	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR13_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.052160 (rank : 165)
Query Neighborhood Hits	51	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H1Z4, Q9BUL7, Q9NWW4	Gene names	WDR13
Domain Architecture
Description	WD repeat protein 13.

WDR13_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.054462 (rank : 139)
Query Neighborhood Hits	51	Target Neighborhood Hits	195	Shared Neighborhood Hits	6
SwissProt Accessions	Q91V09	Gene names	Wdr13
Domain Architecture
Description	WD repeat protein 13.

WDR16_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.057988 (rank : 121)
Query Neighborhood Hits	51	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

WDR16_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.053926 (rank : 145)
Query Neighborhood Hits	51	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

WDR17_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.067521 (rank : 81)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

WDR18_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.063511 (rank : 93)
Query Neighborhood Hits	51	Target Neighborhood Hits	246	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BV38, O60390, Q9BWR2	Gene names	WDR18
Domain Architecture
Description	WD repeat protein 18.

WDR18_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.058461 (rank : 117)
Query Neighborhood Hits	51	Target Neighborhood Hits	239	Shared Neighborhood Hits	8
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

WDR1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.052511 (rank : 163)
Query Neighborhood Hits	51	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	O75083, O75313, Q8N6E5, Q9UG05, Q9UG78, Q9UQE0	Gene names	WDR1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1).

WDR1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.050283 (rank : 178)
Query Neighborhood Hits	51	Target Neighborhood Hits	296	Shared Neighborhood Hits	7
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

WDR31_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.052940 (rank : 158)
Query Neighborhood Hits	51	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

WDR37_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.061973 (rank : 102)
Query Neighborhood Hits	51	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

WDR37_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.063160 (rank : 95)
Query Neighborhood Hits	51	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

WDR3_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.062717 (rank : 99)
Query Neighborhood Hits	51	Target Neighborhood Hits	334	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

WDR41_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.071882 (rank : 71)
Query Neighborhood Hits	51	Target Neighborhood Hits	208	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HAD4, Q7Z792, Q8IWG3, Q8IXA9, Q8NDA7, Q9NV62	Gene names	WDR41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WDR41_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.066321 (rank : 87)
Query Neighborhood Hits	51	Target Neighborhood Hits	209	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UDP0, Q8C4F1, Q8C8K5	Gene names	Wdr41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WDR47_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.053724 (rank : 147)
Query Neighborhood Hits	51	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR47_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.053959 (rank : 144)
Query Neighborhood Hits	51	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR48_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.062034 (rank : 101)
Query Neighborhood Hits	51	Target Neighborhood Hits	291	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAF3, Q63HJ2, Q658Y1, Q8N3Z1, Q9NSK8, Q9P279	Gene names	WDR48, KIAA1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48 (WD repeat endosomal protein) (p80).

WDR48_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.063378 (rank : 94)
Query Neighborhood Hits	51	Target Neighborhood Hits	296	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BH57, Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0	Gene names	Wdr48, Kiaa1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48.

WDR49_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.068366 (rank : 77)
Query Neighborhood Hits	51	Target Neighborhood Hits	214	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

WDR57_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.060721 (rank : 107)
Query Neighborhood Hits	51	Target Neighborhood Hits	322	Shared Neighborhood Hits	10
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

WDR57_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.060283 (rank : 109)
Query Neighborhood Hits	51	Target Neighborhood Hits	323	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

WDR5_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.067446 (rank : 82)
Query Neighborhood Hits	51	Target Neighborhood Hits	341	Shared Neighborhood Hits	11
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.067446 (rank : 83)
Query Neighborhood Hits	51	Target Neighborhood Hits	341	Shared Neighborhood Hits	11
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

WDR61_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.054413 (rank : 140)
Query Neighborhood Hits	51	Target Neighborhood Hits	334	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WDR61_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.054501 (rank : 138)
Query Neighborhood Hits	51	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WDR69_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.066813 (rank : 85)
Query Neighborhood Hits	51	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

WDR6_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.063711 (rank : 92)
Query Neighborhood Hits	51	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NNW5, Q9UF63	Gene names	WDR6
Domain Architecture
Description	WD repeat protein 6.

WDR71_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.065951 (rank : 89)
Query Neighborhood Hits	51	Target Neighborhood Hits	241	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRP4, Q4G165, Q53HS9, Q7Z500, Q8TBU6, Q9HAB6	Gene names	WDR71
Domain Architecture	No domain graphic available
Description	WD repeat protein 71 (Protein G-16).

WSB1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.050415 (rank : 177)
Query Neighborhood Hits	51	Target Neighborhood Hits	337	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

WSB2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.051859 (rank : 168)
Query Neighborhood Hits	51	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

WSB2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.052116 (rank : 166)
Query Neighborhood Hits	51	Target Neighborhood Hits	306	Shared Neighborhood Hits	10
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

ZF106_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.078940 (rank : 65)
Query Neighborhood Hits	51	Target Neighborhood Hits	470	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ZF106_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.081551 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	472	Shared Neighborhood Hits	10
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

Hits sorted by NC score

FBX16_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.37019e-164 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FBX16_MOUSE
NC score	0.986554 (rank : 2)	θ value	2.59848e-140 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	39	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FBXW8_HUMAN
NC score	0.359280 (rank : 3)	θ value	0.000602161 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	192	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBXL5_MOUSE
NC score	0.359139 (rank : 4)	θ value	4.1701e-05 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBXL5_HUMAN
NC score	0.355999 (rank : 5)	θ value	4.1701e-05 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	111	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FBXW8_MOUSE
NC score	0.335308 (rank : 6)	θ value	0.00390308 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	162	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FBX27_HUMAN
NC score	0.310409 (rank : 7)	θ value	0.00175202 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	39	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

FBX2_MOUSE
NC score	0.302673 (rank : 8)	θ value	0.000461057 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q80UW2, Q8R0D2	Gene names	Fbxo2, Fbx2
Domain Architecture	No domain graphic available
Description	F-box only protein 2.

FBXL7_HUMAN
NC score	0.290255 (rank : 9)	θ value	0.000786445 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	91	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FBX27_MOUSE
NC score	0.278683 (rank : 10)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q6DIA9, Q3TYP0, Q8BKF7	Gene names	Fbxo27
Domain Architecture	No domain graphic available
Description	F-box only protein 27.

FXL20_MOUSE
NC score	0.275751 (rank : 11)	θ value	0.00228821 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	78	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_HUMAN
NC score	0.275563 (rank : 12)	θ value	0.00228821 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FBX2_HUMAN
NC score	0.274890 (rank : 13)	θ value	0.0193708 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK22, Q6FGJ7, Q8TB29, Q9UKC6	Gene names	FBXO2, FBX2
Domain Architecture
Description	F-box only protein 2.

FBX6_HUMAN
NC score	0.274207 (rank : 14)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRD1, Q9UKT3	Gene names	FBXO6, FBG2, FBX6
Domain Architecture
Description	F-box only protein 6 (F-box/G-domain protein 2).

FBXL2_HUMAN
NC score	0.266905 (rank : 15)	θ value	0.00298849 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBXL2_MOUSE
NC score	0.265099 (rank : 16)	θ value	0.00390308 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBX17_MOUSE
NC score	0.264628 (rank : 17)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZM8	Gene names	Fbxo17, Fbx17, Fbxo26
Domain Architecture
Description	F-box only protein 17 (F-box only protein 26).

FBX17_HUMAN
NC score	0.251544 (rank : 18)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q96EF6, Q96LQ4	Gene names	FBXO17, FBG4, FBX17, FBX26, FBXO26
Domain Architecture
Description	F-box only protein 17 (F-box only protein 26).

FBX44_MOUSE
NC score	0.250784 (rank : 19)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BK26, Q8K128	Gene names	Fbxo44, Fbxo6a
Domain Architecture	No domain graphic available
Description	F-box only protein 44 (F-box only protein 6a).

FBX44_HUMAN
NC score	0.250658 (rank : 20)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H4M3, Q5TGX2, Q5TGX4, Q5TGX5, Q68DJ9, Q8WWY2	Gene names	FBXO44, FBG3, FBX30, FBX44, FBX6A, FBXO6A
Domain Architecture
Description	F-box only protein 44 (F-box protein FBX30) (F-box/G-domain protein 3).

FBW12_HUMAN
NC score	0.247775 (rank : 21)	θ value	0.00509761 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

FBX4_HUMAN
NC score	0.245540 (rank : 22)	θ value	0.0252991 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKT5, Q68CU8, Q86VT8, Q9UK98	Gene names	FBXO4, FBX4
Domain Architecture
Description	F-box only protein 4.

FBX6_MOUSE
NC score	0.240030 (rank : 23)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZN4, Q3TML5	Gene names	Fbxo6, Fbxo6b
Domain Architecture	No domain graphic available
Description	F-box only protein 6 (F-box only protein 6b).

FBX4_MOUSE
NC score	0.230750 (rank : 24)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CHQ0, Q99JG8	Gene names	Fbxo4, Fbx4
Domain Architecture	No domain graphic available
Description	F-box only protein 4.

FXL12_HUMAN
NC score	0.228471 (rank : 25)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	86	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FBXW7_MOUSE
NC score	0.221649 (rank : 26)	θ value	1.9326e-10 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	365	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXW7_HUMAN
NC score	0.221006 (rank : 27)	θ value	1.9326e-10 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	433	Shared Neighborhood Hits	46
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW2_HUMAN
NC score	0.217563 (rank : 28)	θ value	3.19293e-05 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	260	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

FXL12_MOUSE
NC score	0.215749 (rank : 29)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FBX3_HUMAN
NC score	0.196291 (rank : 30)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UK99, Q9NUX2	Gene names	FBXO3, FBX3
Domain Architecture
Description	F-box only protein 3.

FBXW2_MOUSE
NC score	0.195003 (rank : 31)	θ value	0.00390308 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	249	Shared Neighborhood Hits	14
SwissProt Accessions	Q60584	Gene names	Fbxw2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

FBX11_HUMAN
NC score	0.188197 (rank : 32)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FXL14_MOUSE
NC score	0.176132 (rank : 33)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_HUMAN
NC score	0.175779 (rank : 34)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FBXW4_HUMAN
NC score	0.169724 (rank : 35)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	209	Shared Neighborhood Hits	26
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

FBW1B_HUMAN
NC score	0.165772 (rank : 36)	θ value	0.000121331 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBX3_MOUSE
NC score	0.165290 (rank : 37)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	35	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DC63, Q3TKB0	Gene names	Fbxo3, Fba, Fbx3
Domain Architecture
Description	F-box only protein 3.

FBXW4_MOUSE
NC score	0.160502 (rank : 38)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

FBW1A_HUMAN
NC score	0.159125 (rank : 39)	θ value	0.00228821 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	329	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FXL19_HUMAN
NC score	0.151293 (rank : 40)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	147	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
NC score	0.149867 (rank : 41)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL13_MOUSE
NC score	0.138091 (rank : 42)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	51	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_HUMAN
NC score	0.138064 (rank : 43)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	51	Target Neighborhood Hits	81	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL16_HUMAN
NC score	0.134441 (rank : 44)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	51	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

SKP2_HUMAN
NC score	0.132441 (rank : 45)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	51	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

FBXL4_HUMAN
NC score	0.127618 (rank : 46)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

LRC29_HUMAN
NC score	0.123885 (rank : 47)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

SKP2_MOUSE
NC score	0.121118 (rank : 48)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	51	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

FBX37_MOUSE
NC score	0.116929 (rank : 49)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX37_HUMAN
NC score	0.111273 (rank : 50)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FXL22_MOUSE
NC score	0.101873 (rank : 51)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	51	Target Neighborhood Hits	40	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

SCAP_HUMAN
NC score	0.097512 (rank : 52)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	51	Target Neighborhood Hits	368	Shared Neighborhood Hits	10
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

FBXW9_HUMAN
NC score	0.096911 (rank : 53)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	51	Target Neighborhood Hits	184	Shared Neighborhood Hits	13
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

FBX33_HUMAN
NC score	0.095366 (rank : 54)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

JHD1B_MOUSE
NC score	0.089671 (rank : 55)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	214	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

FBXL6_HUMAN
NC score	0.089277 (rank : 56)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	51	Target Neighborhood Hits	65	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FBX41_HUMAN
NC score	0.086501 (rank : 57)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	475	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX31_HUMAN
NC score	0.086358 (rank : 58)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

JHD1B_HUMAN
NC score	0.082934 (rank : 59)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	51	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

FBX41_MOUSE
NC score	0.082793 (rank : 60)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	430	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

TRAF7_MOUSE
NC score	0.081888 (rank : 61)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	51	Target Neighborhood Hits	470	Shared Neighborhood Hits	9
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.081606 (rank : 62)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	51	Target Neighborhood Hits	482	Shared Neighborhood Hits	9
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

ZF106_MOUSE
NC score	0.081551 (rank : 63)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	51	Target Neighborhood Hits	472	Shared Neighborhood Hits	10
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

FBXL6_MOUSE
NC score	0.080136 (rank : 64)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	51	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

ZF106_HUMAN
NC score	0.078940 (rank : 65)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	51	Target Neighborhood Hits	470	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

JHD1A_HUMAN
NC score	0.076879 (rank : 66)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	51	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
NC score	0.074786 (rank : 67)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	51	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

FXL21_MOUSE
NC score	0.072451 (rank : 68)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

PLAP_HUMAN
NC score	0.072064 (rank : 69)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	51	Target Neighborhood Hits	266	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

PLAP_MOUSE
NC score	0.071886 (rank : 70)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	51	Target Neighborhood Hits	261	Shared Neighborhood Hits	8
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

WDR41_HUMAN
NC score	0.071882 (rank : 71)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	51	Target Neighborhood Hits	208	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HAD4, Q7Z792, Q8IWG3, Q8IXA9, Q8NDA7, Q9NV62	Gene names	WDR41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

PLRG1_MOUSE
NC score	0.071103 (rank : 72)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	51	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

PLRG1_HUMAN
NC score	0.070635 (rank : 73)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	51	Target Neighborhood Hits	318	Shared Neighborhood Hits	10
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

WDR12_MOUSE
NC score	0.069695 (rank : 74)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	51	Target Neighborhood Hits	301	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

AAMP_HUMAN
NC score	0.069174 (rank : 75)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

U3IP2_MOUSE
NC score	0.068938 (rank : 76)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	51	Target Neighborhood Hits	312	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

WDR49_HUMAN
NC score	0.068366 (rank : 77)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	51	Target Neighborhood Hits	214	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

LIS1_HUMAN
NC score	0.068243 (rank : 78)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	51	Target Neighborhood Hits	333	Shared Neighborhood Hits	11
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
NC score	0.068234 (rank : 79)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	51	Target Neighborhood Hits	336	Shared Neighborhood Hits	11
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

PK1IP_MOUSE
NC score	0.067745 (rank : 80)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	51	Target Neighborhood Hits	313	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

WDR17_HUMAN
NC score	0.067521 (rank : 81)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

WDR5_HUMAN
NC score	0.067446 (rank : 82)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	51	Target Neighborhood Hits	341	Shared Neighborhood Hits	11
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
NC score	0.067446 (rank : 83)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	51	Target Neighborhood Hits	341	Shared Neighborhood Hits	11
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

WDR12_HUMAN
NC score	0.067263 (rank : 84)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	51	Target Neighborhood Hits	300	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR69_HUMAN
NC score	0.066813 (rank : 85)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	51	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

U3IP2_HUMAN
NC score	0.066522 (rank : 86)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	51	Target Neighborhood Hits	307	Shared Neighborhood Hits	8
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

WDR41_MOUSE
NC score	0.066321 (rank : 87)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	51	Target Neighborhood Hits	209	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UDP0, Q8C4F1, Q8C8K5	Gene names	Wdr41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

PK1IP_HUMAN
NC score	0.066003 (rank : 88)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	51	Target Neighborhood Hits	277	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

WDR71_HUMAN
NC score	0.065951 (rank : 89)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	51	Target Neighborhood Hits	241	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRP4, Q4G165, Q53HS9, Q7Z500, Q8TBU6, Q9HAB6	Gene names	WDR71
Domain Architecture	No domain graphic available
Description	WD repeat protein 71 (Protein G-16).

COPB2_MOUSE
NC score	0.064045 (rank : 90)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	315	Shared Neighborhood Hits	10
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

COPB2_HUMAN
NC score	0.064023 (rank : 91)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	315	Shared Neighborhood Hits	10
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

WDR6_HUMAN
NC score	0.063711 (rank : 92)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	51	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NNW5, Q9UF63	Gene names	WDR6
Domain Architecture
Description	WD repeat protein 6.

WDR18_HUMAN
NC score	0.063511 (rank : 93)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	51	Target Neighborhood Hits	246	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BV38, O60390, Q9BWR2	Gene names	WDR18
Domain Architecture
Description	WD repeat protein 18.

WDR48_MOUSE
NC score	0.063378 (rank : 94)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	51	Target Neighborhood Hits	296	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BH57, Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0	Gene names	Wdr48, Kiaa1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48.

WDR37_MOUSE
NC score	0.063160 (rank : 95)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	51	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

MORG1_HUMAN
NC score	0.062937 (rank : 96)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	51	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BRX9, Q53FT6	Gene names	MORG1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

MORG1_MOUSE
NC score	0.062894 (rank : 97)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	51	Target Neighborhood Hits	281	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAJ4, Q505C2, Q8VEB7, Q99JX9, Q9D235	Gene names	Morg1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

PRP4_MOUSE
NC score	0.062860 (rank : 98)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	51	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

WDR3_HUMAN
NC score	0.062717 (rank : 99)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	51	Target Neighborhood Hits	334	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

PRP4_HUMAN
NC score	0.062359 (rank : 100)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	51	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

WDR48_HUMAN
NC score	0.062034 (rank : 101)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	51	Target Neighborhood Hits	291	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAF3, Q63HJ2, Q658Y1, Q8N3Z1, Q9NSK8, Q9P279	Gene names	WDR48, KIAA1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48 (WD repeat endosomal protein) (p80).

WDR37_HUMAN
NC score	0.061973 (rank : 102)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	51	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

TBL3_HUMAN
NC score	0.061676 (rank : 103)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	51	Target Neighborhood Hits	286	Shared Neighborhood Hits	8
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

PEX7_MOUSE
NC score	0.061673 (rank : 104)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	51	Target Neighborhood Hits	279	Shared Neighborhood Hits	9
SwissProt Accessions	P97865	Gene names	Pex7
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

PEX7_HUMAN
NC score	0.061249 (rank : 105)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	51	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	O00628	Gene names	PEX7, PTS2R
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

FBX15_HUMAN
NC score	0.060836 (rank : 106)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

WDR57_HUMAN
NC score	0.060721 (rank : 107)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	51	Target Neighborhood Hits	322	Shared Neighborhood Hits	10
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

COPA_HUMAN
NC score	0.060678 (rank : 108)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	297	Shared Neighborhood Hits	8
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

WDR57_MOUSE
NC score	0.060283 (rank : 109)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	51	Target Neighborhood Hits	323	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

NLE1_HUMAN
NC score	0.059615 (rank : 110)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	51	Target Neighborhood Hits	334	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

KTNB1_HUMAN
NC score	0.059487 (rank : 111)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	51	Target Neighborhood Hits	349	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
NC score	0.059462 (rank : 112)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	51	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

PRP17_MOUSE
NC score	0.059293 (rank : 113)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	51	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

PRP17_HUMAN
NC score	0.059020 (rank : 114)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	51	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

SMU1_HUMAN
NC score	0.058555 (rank : 115)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	51	Target Neighborhood Hits	311	Shared Neighborhood Hits	10
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
NC score	0.058555 (rank : 116)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	51	Target Neighborhood Hits	311	Shared Neighborhood Hits	10
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

WDR18_MOUSE
NC score	0.058461 (rank : 117)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	51	Target Neighborhood Hits	239	Shared Neighborhood Hits	8
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

NLE1_MOUSE
NC score	0.058059 (rank : 118)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	51	Target Neighborhood Hits	332	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

GBLP_HUMAN
NC score	0.058025 (rank : 119)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	51	Target Neighborhood Hits	316	Shared Neighborhood Hits	10
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
NC score	0.058025 (rank : 120)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	51	Target Neighborhood Hits	316	Shared Neighborhood Hits	10
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

WDR16_HUMAN
NC score	0.057988 (rank : 121)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	51	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

ERCC8_HUMAN
NC score	0.057744 (rank : 122)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	Q13216, Q6FHX5, Q96GB9	Gene names	ERCC8, CKN1, CSA
Domain Architecture
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA).

ERCC8_MOUSE
NC score	0.057514 (rank : 123)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFD5, Q3U066, Q8VDC4, Q9CWK7	Gene names	Ercc8, Ckn1, Csa
Domain Architecture	No domain graphic available
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog).

UTP15_MOUSE
NC score	0.057141 (rank : 124)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	51	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

APAF_HUMAN
NC score	0.056534 (rank : 125)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	334	Shared Neighborhood Hits	9
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

SPG16_HUMAN
NC score	0.056021 (rank : 126)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	51	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

FBX36_HUMAN
NC score	0.055801 (rank : 127)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEA4, Q8WWD4	Gene names	FBXO36, FBX36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

TEP1_MOUSE
NC score	0.055550 (rank : 128)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	51	Target Neighborhood Hits	344	Shared Neighborhood Hits	11
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

TEP1_HUMAN
NC score	0.055542 (rank : 129)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	51	Target Neighborhood Hits	371	Shared Neighborhood Hits	11
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

UTP15_HUMAN
NC score	0.055459 (rank : 130)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	51	Target Neighborhood Hits	296	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

WD51A_MOUSE
NC score	0.055428 (rank : 131)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	51	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

BRWD1_HUMAN
NC score	0.055368 (rank : 132)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	448	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

APAF_MOUSE
NC score	0.055336 (rank : 133)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	343	Shared Neighborhood Hits	10
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

GBB1_HUMAN
NC score	0.055066 (rank : 134)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	51	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	P62873, P04697, P04901	Gene names	GNB1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB1_MOUSE
NC score	0.055066 (rank : 135)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	51	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	P62874, P04697, P04901	Gene names	Gnb1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

WD51A_HUMAN
NC score	0.054785 (rank : 136)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	51	Target Neighborhood Hits	337	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

GBB3_HUMAN
NC score	0.054593 (rank : 137)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	51	Target Neighborhood Hits	282	Shared Neighborhood Hits	10
SwissProt Accessions	P16520, Q9BQC0	Gene names	GNB3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

WDR61_MOUSE
NC score	0.054501 (rank : 138)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	51	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WDR13_MOUSE
NC score	0.054462 (rank : 139)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	51	Target Neighborhood Hits	195	Shared Neighborhood Hits	6
SwissProt Accessions	Q91V09	Gene names	Wdr13
Domain Architecture
Description	WD repeat protein 13.

WDR61_HUMAN
NC score	0.054413 (rank : 140)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	51	Target Neighborhood Hits	334	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

FBX8_HUMAN
NC score	0.054328 (rank : 141)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	51	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FAN_MOUSE
NC score	0.054227 (rank : 142)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	51	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

TAF5_MOUSE
NC score	0.053970 (rank : 143)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	51	Target Neighborhood Hits	366	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

WDR47_MOUSE
NC score	0.053959 (rank : 144)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	51	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR16_MOUSE
NC score	0.053926 (rank : 145)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	51	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

TAF5_HUMAN
NC score	0.053724 (rank : 146)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	51	Target Neighborhood Hits	352	Shared Neighborhood Hits	9
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

WDR47_HUMAN
NC score	0.053724 (rank : 147)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	51	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

TBL1X_HUMAN
NC score	0.053607 (rank : 148)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	51	Target Neighborhood Hits	329	Shared Neighborhood Hits	8
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

TBLX_MOUSE
NC score	0.053573 (rank : 149)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

TBL1R_HUMAN
NC score	0.053298 (rank : 150)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	51	Target Neighborhood Hits	327	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

WD51B_HUMAN
NC score	0.053272 (rank : 151)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

TBL1R_MOUSE
NC score	0.053251 (rank : 152)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	51	Target Neighborhood Hits	329	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

CDC20_HUMAN
NC score	0.053197 (rank : 153)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	329	Shared Neighborhood Hits	10
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

GBB4_HUMAN
NC score	0.053133 (rank : 154)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	51	Target Neighborhood Hits	288	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HAV0	Gene names	GNB4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

TBL1Y_HUMAN
NC score	0.053091 (rank : 155)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	51	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

PWP1_HUMAN
NC score	0.053039 (rank : 156)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	51	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

GBB3_MOUSE
NC score	0.053005 (rank : 157)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	51	Target Neighborhood Hits	283	Shared Neighborhood Hits	9
SwissProt Accessions	Q61011	Gene names	Gnb3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

WDR31_MOUSE
NC score	0.052940 (rank : 158)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	51	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

BRWD1_MOUSE
NC score	0.052933 (rank : 159)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	478	Shared Neighborhood Hits	10
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

SPG16_MOUSE
NC score	0.052843 (rank : 160)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	51	Target Neighborhood Hits	377	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

WD51B_MOUSE
NC score	0.052832 (rank : 161)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	51	Target Neighborhood Hits	321	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

FBX8_MOUSE
NC score	0.052643 (rank : 162)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	51	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

WDR1_HUMAN
NC score	0.052511 (rank : 163)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	51	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	O75083, O75313, Q8N6E5, Q9UG05, Q9UG78, Q9UQE0	Gene names	WDR1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1).

GBB4_MOUSE
NC score	0.052430 (rank : 164)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	51	Target Neighborhood Hits	283	Shared Neighborhood Hits	9
SwissProt Accessions	P29387, Q3TJJ1, Q8R475, Q9JHX8	Gene names	Gnb4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

WDR13_HUMAN
NC score	0.052160 (rank : 165)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	51	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H1Z4, Q9BUL7, Q9NWW4	Gene names	WDR13
Domain Architecture
Description	WD repeat protein 13.

WSB2_MOUSE
NC score	0.052116 (rank : 166)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	51	Target Neighborhood Hits	306	Shared Neighborhood Hits	10
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

GBB5_MOUSE
NC score	0.051893 (rank : 167)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	51	Target Neighborhood Hits	298	Shared Neighborhood Hits	10
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

WSB2_HUMAN
NC score	0.051859 (rank : 168)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	51	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

CDC20_MOUSE
NC score	0.051773 (rank : 169)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

PWP1_MOUSE
NC score	0.051769 (rank : 170)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	51	Target Neighborhood Hits	278	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

FAN_HUMAN
NC score	0.051623 (rank : 171)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

GBB5_HUMAN
NC score	0.051620 (rank : 172)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	51	Target Neighborhood Hits	299	Shared Neighborhood Hits	10
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

TAF5L_HUMAN
NC score	0.051401 (rank : 173)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	51	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

FBSP1_MOUSE
NC score	0.051358 (rank : 174)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

FBX10_HUMAN
NC score	0.050750 (rank : 175)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	51	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

TAF5L_MOUSE
NC score	0.050686 (rank : 176)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	51	Target Neighborhood Hits	337	Shared Neighborhood Hits	9
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

WSB1_HUMAN
NC score	0.050415 (rank : 177)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	51	Target Neighborhood Hits	337	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

WDR1_MOUSE
NC score	0.050283 (rank : 178)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	51	Target Neighborhood Hits	296	Shared Neighborhood Hits	7
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

SAMD4_MOUSE
NC score	0.021174 (rank : 179)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

AGAL_HUMAN
NC score	0.015277 (rank : 180)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P06280	Gene names	GLA
Domain Architecture
Description	Alpha-galactosidase A precursor (EC 3.2.1.22) (Melibiase) (Alpha-D- galactoside galactohydrolase) (Alpha-D-galactosidase A) (Agalsidase alfa).