Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : FBW12_HUMAN

For an explanation of this page, click here

FBW12_HUMAN
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBW12_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

FXL12_MOUSE
θ value	0.00175202 (rank : 2)	NC score	0.284806 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL12_HUMAN
θ value	0.00390308 (rank : 3)	NC score	0.281780 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FBX16_HUMAN
θ value	0.00509761 (rank : 4)	NC score	0.247775 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

SKP2_HUMAN
θ value	0.0113563 (rank : 5)	NC score	0.249302 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

FBXL2_HUMAN
θ value	0.0252991 (rank : 6)	NC score	0.228669 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBXL2_MOUSE
θ value	0.0252991 (rank : 7)	NC score	0.228687 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

NEDD1_HUMAN
θ value	0.0252991 (rank : 8)	NC score	0.093994 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	294	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

SKP2_MOUSE
θ value	0.0330416 (rank : 9)	NC score	0.241313 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

FBX16_MOUSE
θ value	0.0431538 (rank : 10)	NC score	0.224133 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FXL20_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.226296 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
θ value	0.0563607 (rank : 12)	NC score	0.226836 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

RAE1L_HUMAN
θ value	0.0563607 (rank : 13)	NC score	0.109429 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	222	Shared Neighborhood Hits	21
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

RAE1L_MOUSE
θ value	0.0563607 (rank : 14)	NC score	0.110108 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

FBXW8_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.168340 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	192	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBXL7_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.219777 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

TEP1_MOUSE
θ value	0.163984 (rank : 17)	NC score	0.084746 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	344	Shared Neighborhood Hits	26
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

FBSP1_MOUSE
θ value	0.21417 (rank : 18)	NC score	0.087888 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

FBX36_MOUSE
θ value	0.21417 (rank : 19)	NC score	0.133835 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CQ24	Gene names	Fbxo36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

PK1IP_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.073817 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	313	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

FBXL5_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.173913 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	103	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

WDR31_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.071689 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	287	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

FBXL5_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.166044 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

TEP1_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.072345 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	371	Shared Neighborhood Hits	26
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

FBX36_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.127487 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NEA4, Q8WWD4	Gene names	FBXO36, FBX36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

FBXW4_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.091996 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	209	Shared Neighborhood Hits	35
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

FXL13_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.159294 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

WDR31_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.066293 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	282	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NA23, Q96EG8	Gene names	WDR31
Domain Architecture
Description	WD repeat protein 31.

FBXW5_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.072079 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	156	Shared Neighborhood Hits	25
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBXW7_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.083043 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	433	Shared Neighborhood Hits	50
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.082929 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	365	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXW8_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.139532 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	162	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FXL13_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.152867 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

KI21A_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.024683 (rank : 81)
Query Neighborhood Hits	60	Target Neighborhood Hits	1543	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

SAHH_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.023338 (rank : 83)
Query Neighborhood Hits	60	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).

SERC3_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.023302 (rank : 84)
Query Neighborhood Hits	60	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q13530, O43717, Q9BR33	Gene names	SERINC3, DIFF33, TDE1
Domain Architecture
Description	Serine incorporator 3 (Tumor differentially expressed protein 1).

BCL2_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.032451 (rank : 78)
Query Neighborhood Hits	60	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P10415, P10416, Q13842, Q16197	Gene names	BCL2
Domain Architecture
Description	Apoptosis regulator Bcl-2.

BCL2_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.032379 (rank : 79)
Query Neighborhood Hits	60	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P10417, P10418	Gene names	Bcl2, Bcl-2
Domain Architecture
Description	Apoptosis regulator Bcl-2.

CDC20_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.054133 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

CDC20_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.053943 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

FBXW4_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.086332 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	205	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

EMAL4_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.039543 (rank : 77)
Query Neighborhood Hits	60	Target Neighborhood Hits	306	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

FBX15_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.059658 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBX39_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.060162 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

FBX3_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.054491 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UK99, Q9NUX2	Gene names	FBXO3, FBX3
Domain Architecture
Description	F-box only protein 3.

FBXW5_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.065410 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	159	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

I13R2_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.024265 (rank : 82)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

WDFY2_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.042637 (rank : 75)
Query Neighborhood Hits	60	Target Neighborhood Hits	332	Shared Neighborhood Hits	22
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDR5_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.052797 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	341	Shared Neighborhood Hits	28
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.052797 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	341	Shared Neighborhood Hits	28
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

FBX11_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.116817 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FBX4_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.059399 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKT5, Q68CU8, Q86VT8, Q9UK98	Gene names	FBXO4, FBX4
Domain Architecture
Description	F-box only protein 4.

FBXL3_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.062848 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKT7, Q9P122	Gene names	FBXL3, FBL3A, FBXL3A
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FBXL3_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.061395 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C4V4, Q80V32, Q8K1W0, Q9QXW1	Gene names	Fbxl3, Fbl3a, Fbxl3a
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FXL21_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.093739 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

LIS1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.048273 (rank : 73)
Query Neighborhood Hits	60	Target Neighborhood Hits	333	Shared Neighborhood Hits	28
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.048272 (rank : 74)
Query Neighborhood Hits	60	Target Neighborhood Hits	336	Shared Neighborhood Hits	28
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

SIRPG_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.010222 (rank : 85)
Query Neighborhood Hits	60	Target Neighborhood Hits	359	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P1W8, Q8WWA5, Q9NQK8	Gene names	SIRPG, SIRPB2
Domain Architecture
Description	Signal-regulatory protein gamma precursor (Signal-regulatory protein beta-2) (SIRP-beta-2) (SIRP-b2) (CD172g antigen).

TLE2_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.030963 (rank : 80)
Query Neighborhood Hits	60	Target Neighborhood Hits	321	Shared Neighborhood Hits	24
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

WDFY2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.041110 (rank : 76)
Query Neighborhood Hits	60	Target Neighborhood Hits	337	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

BUB3_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.057222 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	200	Shared Neighborhood Hits	18
SwissProt Accessions	O43684, O43685	Gene names	BUB3
Domain Architecture
Description	Mitotic checkpoint protein BUB3.

BUB3_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.057067 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVA3, P97397	Gene names	Bub3
Domain Architecture
Description	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5).

FBW1A_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.057891 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FBW1B_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.059048 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	327	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBX33_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.058922 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

FBX37_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.102709 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX37_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.108553 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBXL4_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.122594 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

FBXL6_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.084123 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FBXL6_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.074520 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

FBXW2_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.054654 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

FXL14_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.134747 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.135128 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL16_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.130412 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL19_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.071770 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	147	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.070911 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL21_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.068005 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

FXL22_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.104693 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

JHD1A_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.052859 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.051683 (rank : 72)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

JHD1B_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.057484 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.057142 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

LRC29_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.107675 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

NEDD1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.056400 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

PK1IP_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.052483 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	277	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

Hits sorted by NC score

FBW12_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

FXL12_MOUSE
NC score	0.284806 (rank : 2)	θ value	0.00175202 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL12_HUMAN
NC score	0.281780 (rank : 3)	θ value	0.00390308 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

SKP2_HUMAN
NC score	0.249302 (rank : 4)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

FBX16_HUMAN
NC score	0.247775 (rank : 5)	θ value	0.00509761 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

SKP2_MOUSE
NC score	0.241313 (rank : 6)	θ value	0.0330416 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

FBXL2_MOUSE
NC score	0.228687 (rank : 7)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXL2_HUMAN
NC score	0.228669 (rank : 8)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FXL20_MOUSE
NC score	0.226836 (rank : 9)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_HUMAN
NC score	0.226296 (rank : 10)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FBX16_MOUSE
NC score	0.224133 (rank : 11)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FBXL7_HUMAN
NC score	0.219777 (rank : 12)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FBXL5_MOUSE
NC score	0.173913 (rank : 13)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	103	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBXW8_HUMAN
NC score	0.168340 (rank : 14)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	192	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBXL5_HUMAN
NC score	0.166044 (rank : 15)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FXL13_HUMAN
NC score	0.159294 (rank : 16)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_MOUSE
NC score	0.152867 (rank : 17)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FBXW8_MOUSE
NC score	0.139532 (rank : 18)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	162	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FXL14_MOUSE
NC score	0.135128 (rank : 19)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	60	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_HUMAN
NC score	0.134747 (rank : 20)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	60	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FBX36_MOUSE
NC score	0.133835 (rank : 21)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CQ24	Gene names	Fbxo36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

FXL16_HUMAN
NC score	0.130412 (rank : 22)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	60	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FBX36_HUMAN
NC score	0.127487 (rank : 23)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NEA4, Q8WWD4	Gene names	FBXO36, FBX36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

FBXL4_HUMAN
NC score	0.122594 (rank : 24)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

FBX11_HUMAN
NC score	0.116817 (rank : 25)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

RAE1L_MOUSE
NC score	0.110108 (rank : 26)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

RAE1L_HUMAN
NC score	0.109429 (rank : 27)	θ value	0.0563607 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	222	Shared Neighborhood Hits	21
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

FBX37_MOUSE
NC score	0.108553 (rank : 28)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

LRC29_HUMAN
NC score	0.107675 (rank : 29)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

FXL22_MOUSE
NC score	0.104693 (rank : 30)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

FBX37_HUMAN
NC score	0.102709 (rank : 31)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

NEDD1_HUMAN
NC score	0.093994 (rank : 32)	θ value	0.0252991 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	294	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

FXL21_MOUSE
NC score	0.093739 (rank : 33)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

FBXW4_HUMAN
NC score	0.091996 (rank : 34)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	209	Shared Neighborhood Hits	35
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

FBSP1_MOUSE
NC score	0.087888 (rank : 35)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

FBXW4_MOUSE
NC score	0.086332 (rank : 36)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	205	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

TEP1_MOUSE
NC score	0.084746 (rank : 37)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	344	Shared Neighborhood Hits	26
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

FBXL6_HUMAN
NC score	0.084123 (rank : 38)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FBXW7_HUMAN
NC score	0.083043 (rank : 39)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	433	Shared Neighborhood Hits	50
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
NC score	0.082929 (rank : 40)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	365	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXL6_MOUSE
NC score	0.074520 (rank : 41)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

PK1IP_MOUSE
NC score	0.073817 (rank : 42)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	313	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

TEP1_HUMAN
NC score	0.072345 (rank : 43)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	371	Shared Neighborhood Hits	26
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

FBXW5_HUMAN
NC score	0.072079 (rank : 44)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	156	Shared Neighborhood Hits	25
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FXL19_HUMAN
NC score	0.071770 (rank : 45)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	60	Target Neighborhood Hits	147	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

WDR31_MOUSE
NC score	0.071689 (rank : 46)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	287	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

FXL19_MOUSE
NC score	0.070911 (rank : 47)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	60	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL21_HUMAN
NC score	0.068005 (rank : 48)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	60	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

WDR31_HUMAN
NC score	0.066293 (rank : 49)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	282	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NA23, Q96EG8	Gene names	WDR31
Domain Architecture
Description	WD repeat protein 31.

FBXW5_MOUSE
NC score	0.065410 (rank : 50)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	159	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBXL3_HUMAN
NC score	0.062848 (rank : 51)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKT7, Q9P122	Gene names	FBXL3, FBL3A, FBXL3A
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FBXL3_MOUSE
NC score	0.061395 (rank : 52)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C4V4, Q80V32, Q8K1W0, Q9QXW1	Gene names	Fbxl3, Fbl3a, Fbxl3a
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FBX39_MOUSE
NC score	0.060162 (rank : 53)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

FBX15_HUMAN
NC score	0.059658 (rank : 54)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBX4_HUMAN
NC score	0.059399 (rank : 55)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKT5, Q68CU8, Q86VT8, Q9UK98	Gene names	FBXO4, FBX4
Domain Architecture
Description	F-box only protein 4.

FBW1B_HUMAN
NC score	0.059048 (rank : 56)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	327	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBX33_HUMAN
NC score	0.058922 (rank : 57)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

FBW1A_HUMAN
NC score	0.057891 (rank : 58)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

JHD1B_HUMAN
NC score	0.057484 (rank : 59)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	60	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

BUB3_HUMAN
NC score	0.057222 (rank : 60)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	200	Shared Neighborhood Hits	18
SwissProt Accessions	O43684, O43685	Gene names	BUB3
Domain Architecture
Description	Mitotic checkpoint protein BUB3.

JHD1B_MOUSE
NC score	0.057142 (rank : 61)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	60	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

BUB3_MOUSE
NC score	0.057067 (rank : 62)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVA3, P97397	Gene names	Bub3
Domain Architecture
Description	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5).

NEDD1_MOUSE
NC score	0.056400 (rank : 63)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	60	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

FBXW2_HUMAN
NC score	0.054654 (rank : 64)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

FBX3_HUMAN
NC score	0.054491 (rank : 65)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UK99, Q9NUX2	Gene names	FBXO3, FBX3
Domain Architecture
Description	F-box only protein 3.

CDC20_HUMAN
NC score	0.054133 (rank : 66)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

CDC20_MOUSE
NC score	0.053943 (rank : 67)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

JHD1A_HUMAN
NC score	0.052859 (rank : 68)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	60	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

WDR5_HUMAN
NC score	0.052797 (rank : 69)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	341	Shared Neighborhood Hits	28
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
NC score	0.052797 (rank : 70)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	341	Shared Neighborhood Hits	28
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

PK1IP_HUMAN
NC score	0.052483 (rank : 71)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	60	Target Neighborhood Hits	277	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

JHD1A_MOUSE
NC score	0.051683 (rank : 72)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

LIS1_HUMAN
NC score	0.048273 (rank : 73)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	333	Shared Neighborhood Hits	28
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
NC score	0.048272 (rank : 74)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	336	Shared Neighborhood Hits	28
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

WDFY2_HUMAN
NC score	0.042637 (rank : 75)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	332	Shared Neighborhood Hits	22
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
NC score	0.041110 (rank : 76)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	337	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

EMAL4_HUMAN
NC score	0.039543 (rank : 77)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	306	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

BCL2_HUMAN
NC score	0.032451 (rank : 78)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P10415, P10416, Q13842, Q16197	Gene names	BCL2
Domain Architecture
Description	Apoptosis regulator Bcl-2.

BCL2_MOUSE
NC score	0.032379 (rank : 79)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P10417, P10418	Gene names	Bcl2, Bcl-2
Domain Architecture
Description	Apoptosis regulator Bcl-2.

TLE2_HUMAN
NC score	0.030963 (rank : 80)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	321	Shared Neighborhood Hits	24
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

KI21A_HUMAN
NC score	0.024683 (rank : 81)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	1543	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

I13R2_HUMAN
NC score	0.024265 (rank : 82)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

SAHH_HUMAN
NC score	0.023338 (rank : 83)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).

SERC3_HUMAN
NC score	0.023302 (rank : 84)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q13530, O43717, Q9BR33	Gene names	SERINC3, DIFF33, TDE1
Domain Architecture
Description	Serine incorporator 3 (Tumor differentially expressed protein 1).

SIRPG_HUMAN
NC score	0.010222 (rank : 85)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	359	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P1W8, Q8WWA5, Q9NQK8	Gene names	SIRPG, SIRPB2
Domain Architecture
Description	Signal-regulatory protein gamma precursor (Signal-regulatory protein beta-2) (SIRP-beta-2) (SIRP-b2) (CD172g antigen).