Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : SAHH_HUMAN

For an explanation of this page, click here

SAHH_HUMAN
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SAHH_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).

SAHH_MOUSE
θ value	0 (rank : 2)	NC score	0.999683 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	P50247, Q91WF1	Gene names	Ahcy
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) (Liver copper-binding protein) (CUBP).

SAHH3_HUMAN
θ value	5.8157e-124 (rank : 3)	NC score	0.973240 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q96HN2, O94917	Gene names	KIAA0828
Domain Architecture
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SAHH3_MOUSE
θ value	5.8157e-124 (rank : 4)	NC score	0.971638 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q68FL4, Q8BIH1	Gene names
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SAHH2_HUMAN
θ value	3.52827e-121 (rank : 5)	NC score	0.975461 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O43865, Q2TAJ6, Q502W8, Q6P171, Q96PK4	Gene names	AHCYL1, DCAL, XPVKONA
Domain Architecture
Description	Putative adenosylhomocysteinase 2 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (DC-expressed AHCY-like molecule).

SAHH2_MOUSE
θ value	3.52827e-121 (rank : 6)	NC score	0.975461 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q80SW1	Gene names	Ahcyl1, Irbit
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 2 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (IP3R-binding protein released with inositol 1,4,5- trisphosphate).

DHR10_HUMAN
θ value	0.0961366 (rank : 7)	NC score	0.042031 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BPX1, Q9UKU3	Gene names	DHRS10, SDR3
Domain Architecture	No domain graphic available
Description	Dehydrogenase/reductase SDR family member 10 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase retSDR3).

RDH12_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.024150 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NR8, Q8TAW6	Gene names	RDH12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis retinol dehydrogenase).

GRHPR_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.023757 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

RDH12_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.022791 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYK4, Q91WA5, Q9D1Y4	Gene names	Rdh12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-).

FBW12_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.023338 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

DCXR_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.018701 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z4W1, Q9BTZ3, Q9UHY9	Gene names	DCXR
Domain Architecture	No domain graphic available
Description	L-xylulose reductase (EC 1.1.1.10) (XR) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Carbonyl reductase II) (Sperm surface protein P34H).

SH2D3_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.007596 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

Hits sorted by NC score

SAHH_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).

SAHH_MOUSE
NC score	0.999683 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	P50247, Q91WF1	Gene names	Ahcy
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) (Liver copper-binding protein) (CUBP).

SAHH2_HUMAN
NC score	0.975461 (rank : 3)	θ value	3.52827e-121 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O43865, Q2TAJ6, Q502W8, Q6P171, Q96PK4	Gene names	AHCYL1, DCAL, XPVKONA
Domain Architecture
Description	Putative adenosylhomocysteinase 2 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (DC-expressed AHCY-like molecule).

SAHH2_MOUSE
NC score	0.975461 (rank : 4)	θ value	3.52827e-121 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q80SW1	Gene names	Ahcyl1, Irbit
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 2 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (IP3R-binding protein released with inositol 1,4,5- trisphosphate).

SAHH3_HUMAN
NC score	0.973240 (rank : 5)	θ value	5.8157e-124 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q96HN2, O94917	Gene names	KIAA0828
Domain Architecture
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SAHH3_MOUSE
NC score	0.971638 (rank : 6)	θ value	5.8157e-124 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q68FL4, Q8BIH1	Gene names
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

DHR10_HUMAN
NC score	0.042031 (rank : 7)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BPX1, Q9UKU3	Gene names	DHRS10, SDR3
Domain Architecture	No domain graphic available
Description	Dehydrogenase/reductase SDR family member 10 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase retSDR3).

RDH12_HUMAN
NC score	0.024150 (rank : 8)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NR8, Q8TAW6	Gene names	RDH12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis retinol dehydrogenase).

GRHPR_HUMAN
NC score	0.023757 (rank : 9)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

FBW12_HUMAN
NC score	0.023338 (rank : 10)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

RDH12_MOUSE
NC score	0.022791 (rank : 11)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYK4, Q91WA5, Q9D1Y4	Gene names	Rdh12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-).

DCXR_HUMAN
NC score	0.018701 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z4W1, Q9BTZ3, Q9UHY9	Gene names	DCXR
Domain Architecture	No domain graphic available
Description	L-xylulose reductase (EC 1.1.1.10) (XR) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Carbonyl reductase II) (Sperm surface protein P34H).

SH2D3_MOUSE
NC score	0.007596 (rank : 13)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).