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Network neighborhood for query Sequence : SAHH_MOUSE

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SAHH_MOUSE
SwissProt Accessions	P50247, Q91WF1	Gene names	Ahcy
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) (Liver copper-binding protein) (CUBP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SAHH_HUMAN
θ value	0 (rank : 1)	NC score	0.999683 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).

SAHH_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P50247, Q91WF1	Gene names	Ahcy
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) (Liver copper-binding protein) (CUBP).

SAHH3_HUMAN
θ value	1.38424e-125 (rank : 3)	NC score	0.974040 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q96HN2, O94917	Gene names	KIAA0828
Domain Architecture
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SAHH3_MOUSE
θ value	1.38424e-125 (rank : 4)	NC score	0.972437 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q68FL4, Q8BIH1	Gene names
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SAHH2_HUMAN
θ value	8.39787e-123 (rank : 5)	NC score	0.976266 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O43865, Q2TAJ6, Q502W8, Q6P171, Q96PK4	Gene names	AHCYL1, DCAL, XPVKONA
Domain Architecture
Description	Putative adenosylhomocysteinase 2 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (DC-expressed AHCY-like molecule).

SAHH2_MOUSE
θ value	8.39787e-123 (rank : 6)	NC score	0.976266 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q80SW1	Gene names	Ahcyl1, Irbit
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 2 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (IP3R-binding protein released with inositol 1,4,5- trisphosphate).

DHR10_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.039273 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BPX1, Q9UKU3	Gene names	DHRS10, SDR3
Domain Architecture	No domain graphic available
Description	Dehydrogenase/reductase SDR family member 10 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase retSDR3).

RDH12_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.023623 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NR8, Q8TAW6	Gene names	RDH12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis retinol dehydrogenase).

RDH12_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.022310 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYK4, Q91WA5, Q9D1Y4	Gene names	Rdh12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-).

DCXR_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.017569 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z4W1, Q9BTZ3, Q9UHY9	Gene names	DCXR
Domain Architecture	No domain graphic available
Description	L-xylulose reductase (EC 1.1.1.10) (XR) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Carbonyl reductase II) (Sperm surface protein P34H).

GRHPR_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.024974 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

CF211_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.015034 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H993, Q96FC6, Q9UFY5	Gene names	C6orf211
Domain Architecture	No domain graphic available
Description	UPF0364 protein C6orf211.

GRHPR_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.014407 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Z53	Gene names	Grhpr, Glxr
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

JAK3_HUMAN
θ value	8.99809 (rank : 14)	NC score	-0.000650 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	827	Shared Neighborhood Hits	2
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

Hits sorted by NC score

SAHH_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P50247, Q91WF1	Gene names	Ahcy
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) (Liver copper-binding protein) (CUBP).

SAHH_HUMAN
NC score	0.999683 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).

SAHH2_HUMAN
NC score	0.976266 (rank : 3)	θ value	8.39787e-123 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O43865, Q2TAJ6, Q502W8, Q6P171, Q96PK4	Gene names	AHCYL1, DCAL, XPVKONA
Domain Architecture
Description	Putative adenosylhomocysteinase 2 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (DC-expressed AHCY-like molecule).

SAHH2_MOUSE
NC score	0.976266 (rank : 4)	θ value	8.39787e-123 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q80SW1	Gene names	Ahcyl1, Irbit
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 2 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (IP3R-binding protein released with inositol 1,4,5- trisphosphate).

SAHH3_HUMAN
NC score	0.974040 (rank : 5)	θ value	1.38424e-125 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q96HN2, O94917	Gene names	KIAA0828
Domain Architecture
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SAHH3_MOUSE
NC score	0.972437 (rank : 6)	θ value	1.38424e-125 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q68FL4, Q8BIH1	Gene names
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

DHR10_HUMAN
NC score	0.039273 (rank : 7)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BPX1, Q9UKU3	Gene names	DHRS10, SDR3
Domain Architecture	No domain graphic available
Description	Dehydrogenase/reductase SDR family member 10 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase retSDR3).

GRHPR_HUMAN
NC score	0.024974 (rank : 8)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

RDH12_HUMAN
NC score	0.023623 (rank : 9)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NR8, Q8TAW6	Gene names	RDH12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis retinol dehydrogenase).

RDH12_MOUSE
NC score	0.022310 (rank : 10)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYK4, Q91WA5, Q9D1Y4	Gene names	Rdh12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-).

DCXR_HUMAN
NC score	0.017569 (rank : 11)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z4W1, Q9BTZ3, Q9UHY9	Gene names	DCXR
Domain Architecture	No domain graphic available
Description	L-xylulose reductase (EC 1.1.1.10) (XR) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Carbonyl reductase II) (Sperm surface protein P34H).

CF211_HUMAN
NC score	0.015034 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H993, Q96FC6, Q9UFY5	Gene names	C6orf211
Domain Architecture	No domain graphic available
Description	UPF0364 protein C6orf211.

GRHPR_MOUSE
NC score	0.014407 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Z53	Gene names	Grhpr, Glxr
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

JAK3_HUMAN
NC score	-0.000650 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	827	Shared Neighborhood Hits	2
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).