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Network neighborhood for query Sequence : GRHPR_HUMAN

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GRHPR_HUMAN
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRHPR_HUMAN
θ value	1.96665e-180 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

GRHPR_MOUSE
θ value	6.80647e-157 (rank : 2)	NC score	0.998285 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q91Z53	Gene names	Grhpr, Glxr
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

SERA_MOUSE
θ value	3.3877e-31 (rank : 3)	NC score	0.818257 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q61753, Q75SV9	Gene names	Phgdh
Domain Architecture	No domain graphic available
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH) (A10).

SERA_HUMAN
θ value	5.77852e-31 (rank : 4)	NC score	0.818895 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O43175, Q5SZU3, Q9BQ01	Gene names	PHGDH, PGDH3
Domain Architecture
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH).

CTBP1_HUMAN
θ value	1.38178e-16 (rank : 5)	NC score	0.693983 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q13363	Gene names	CTBP1, CTBP
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP1_MOUSE
θ value	1.80466e-16 (rank : 6)	NC score	0.692874 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	O88712, Q9QYG2	Gene names	Ctbp1
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP2_MOUSE
θ value	5.25075e-16 (rank : 7)	NC score	0.682192 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	P56546, O54855, O88462	Gene names	Ctbp2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

CTBP2_HUMAN
θ value	6.85773e-16 (rank : 8)	NC score	0.682468 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	P56545, O43449	Gene names	CTBP2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

3HIDH_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.031414 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q99L13, Q8BJY2	Gene names	Hibadh
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

SAHH_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.023757 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).

JIP4_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.013740 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	593	Shared Neighborhood Hits	3
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

SAHH_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.024974 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P50247, Q91WF1	Gene names	Ahcy
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) (Liver copper-binding protein) (CUBP).

JIP4_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.012791 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	585	Shared Neighborhood Hits	3
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

Hits sorted by NC score

GRHPR_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.96665e-180 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBQ7, Q9H3E9, Q9UKX1	Gene names	GRHPR, GLXR
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

GRHPR_MOUSE
NC score	0.998285 (rank : 2)	θ value	6.80647e-157 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q91Z53	Gene names	Grhpr, Glxr
Domain Architecture
Description	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79).

SERA_HUMAN
NC score	0.818895 (rank : 3)	θ value	5.77852e-31 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O43175, Q5SZU3, Q9BQ01	Gene names	PHGDH, PGDH3
Domain Architecture
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH).

SERA_MOUSE
NC score	0.818257 (rank : 4)	θ value	3.3877e-31 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q61753, Q75SV9	Gene names	Phgdh
Domain Architecture	No domain graphic available
Description	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH) (A10).

CTBP1_HUMAN
NC score	0.693983 (rank : 5)	θ value	1.38178e-16 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q13363	Gene names	CTBP1, CTBP
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP1_MOUSE
NC score	0.692874 (rank : 6)	θ value	1.80466e-16 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	O88712, Q9QYG2	Gene names	Ctbp1
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP2_HUMAN
NC score	0.682468 (rank : 7)	θ value	6.85773e-16 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	P56545, O43449	Gene names	CTBP2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

CTBP2_MOUSE
NC score	0.682192 (rank : 8)	θ value	5.25075e-16 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	P56546, O54855, O88462	Gene names	Ctbp2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

3HIDH_MOUSE
NC score	0.031414 (rank : 9)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q99L13, Q8BJY2	Gene names	Hibadh
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

SAHH_MOUSE
NC score	0.024974 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P50247, Q91WF1	Gene names	Ahcy
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) (Liver copper-binding protein) (CUBP).

SAHH_HUMAN
NC score	0.023757 (rank : 11)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P23526, Q96A36	Gene names	AHCY, SAHH
Domain Architecture
Description	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase).

JIP4_MOUSE
NC score	0.013740 (rank : 12)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	593	Shared Neighborhood Hits	3
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

JIP4_HUMAN
NC score	0.012791 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	585	Shared Neighborhood Hits	3
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).