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Network neighborhood for query Sequence : MCCC2_HUMAN

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MCCC2_HUMAN
SwissProt Accessions	Q9HCC0, Q96C27, Q9Y4L7	Gene names	MCCC2, MCCB
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.4) (3-Methylcrotonyl-CoA carboxylase 2) (MCCase subunit beta) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) (3- Methylcrotonyl-CoA carboxylase non-biotin-containing subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MCCC2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCC0, Q96C27, Q9Y4L7	Gene names	MCCC2, MCCB
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.4) (3-Methylcrotonyl-CoA carboxylase 2) (MCCase subunit beta) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) (3- Methylcrotonyl-CoA carboxylase non-biotin-containing subunit).

PCCB_HUMAN
θ value	1.11734e-58 (rank : 2)	NC score	0.873050 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P05166, Q16813	Gene names	PCCB
Domain Architecture
Description	Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

PCCB_MOUSE
θ value	5.54529e-58 (rank : 3)	NC score	0.870948 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MN9	Gene names	Pccb
Domain Architecture	No domain graphic available
Description	Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

COA2_HUMAN
θ value	9.29e-05 (rank : 4)	NC score	0.249906 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	184	Shared Neighborhood Hits	5
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

COA1_HUMAN
θ value	0.00102713 (rank : 5)	NC score	0.239731 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

HECD3_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.026119 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.025918 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

TRI45_MOUSE
θ value	6.88961 (rank : 8)	NC score	0.011360 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

Hits sorted by NC score

MCCC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCC0, Q96C27, Q9Y4L7	Gene names	MCCC2, MCCB
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.4) (3-Methylcrotonyl-CoA carboxylase 2) (MCCase subunit beta) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) (3- Methylcrotonyl-CoA carboxylase non-biotin-containing subunit).

PCCB_HUMAN
NC score	0.873050 (rank : 2)	θ value	1.11734e-58 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P05166, Q16813	Gene names	PCCB
Domain Architecture
Description	Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

PCCB_MOUSE
NC score	0.870948 (rank : 3)	θ value	5.54529e-58 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MN9	Gene names	Pccb
Domain Architecture	No domain graphic available
Description	Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

COA2_HUMAN
NC score	0.249906 (rank : 4)	θ value	9.29e-05 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	184	Shared Neighborhood Hits	5
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

COA1_HUMAN
NC score	0.239731 (rank : 5)	θ value	0.00102713 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

HECD3_HUMAN
NC score	0.026119 (rank : 6)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
NC score	0.025918 (rank : 7)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

TRI45_MOUSE
NC score	0.011360 (rank : 8)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.