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Network neighborhood for query Sequence : PCCA_HUMAN

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PCCA_HUMAN
 
SwissProt Accessions P05165, Q15979 Gene names PCCA
Domain
Architecture
Description Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).
Rank Plots


Hits sorted by θ


PCCA_HUMAN
 
θ value 0 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 22 Target Neighborhood Hits 22 Shared Neighborhood Hits 22
SwissProt Accessions P05165, Q15979 Gene names PCCA
Domain
Architecture
Description Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).
PCCA_MOUSE
 
θ value 0 (rank : 2) NC score 0.999289 (rank : 2)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 16
SwissProt Accessions Q91ZA3, Q80VU5, Q922N3 Gene names Pcca
Domain
Architecture

No domain graphic available

Description Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).
MCCA_MOUSE
 
θ value 6.19918e-134 (rank : 3) NC score 0.967448 (rank : 3)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 15
SwissProt Accessions Q99MR8, Q3TGU0, Q9D8R2 Gene names Mccc1, Mcca
Domain
Architecture
Description Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).
MCCA_HUMAN
 
θ value 4.44261e-132 (rank : 4) NC score 0.966541 (rank : 4)
Query Neighborhood Hits 22 Target Neighborhood Hits 26 Shared Neighborhood Hits 15
SwissProt Accessions Q96RQ3, Q59ES4, Q9H959, Q9NS97 Gene names MCCC1, MCCA
Domain
Architecture
Description Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).
PYC_HUMAN
 
θ value 1.34698e-104 (rank : 5) NC score 0.930919 (rank : 5)
Query Neighborhood Hits 22 Target Neighborhood Hits 25 Shared Neighborhood Hits 12
SwissProt Accessions P11498, Q16705 Gene names PC
Domain
Architecture
Description Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).
PYC_MOUSE
 
θ value 1.14028e-103 (rank : 6) NC score 0.930753 (rank : 6)
Query Neighborhood Hits 22 Target Neighborhood Hits 25 Shared Neighborhood Hits 11
SwissProt Accessions Q05920 Gene names Pc, Pcx
Domain
Architecture
Description Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).
COA1_HUMAN
 
θ value 4.84666e-62 (rank : 7) NC score 0.824433 (rank : 7)
Query Neighborhood Hits 22 Target Neighborhood Hits 49 Shared Neighborhood Hits 11
SwissProt Accessions Q13085 Gene names ACACA, ACAC, ACC1, ACCA
Domain
Architecture
Description Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].
COA2_HUMAN
 
θ value 2.10721e-57 (rank : 8) NC score 0.790805 (rank : 8)
Query Neighborhood Hits 22 Target Neighborhood Hits 184 Shared Neighborhood Hits 11
SwissProt Accessions O00763, Q16852 Gene names ACACB, ACC2, ACCB
Domain
Architecture
Description Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].
PYR1_HUMAN
 
θ value 9.59137e-10 (rank : 9) NC score 0.392575 (rank : 11)
Query Neighborhood Hits 22 Target Neighborhood Hits 119 Shared Neighborhood Hits 12
SwissProt Accessions P27708, Q6P0Q0 Gene names CAD
Domain
Architecture

No domain graphic available

Description CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].
CPSM_HUMAN
 
θ value 8.97725e-08 (rank : 10) NC score 0.394704 (rank : 10)
Query Neighborhood Hits 22 Target Neighborhood Hits 27 Shared Neighborhood Hits 13
SwissProt Accessions P31327, O43774, Q7Z5I5 Gene names CPS1
Domain
Architecture
Description Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).
CPSM_MOUSE
 
θ value 1.99992e-07 (rank : 11) NC score 0.399047 (rank : 9)
Query Neighborhood Hits 22 Target Neighborhood Hits 32 Shared Neighborhood Hits 13
SwissProt Accessions Q8C196, Q6NX75 Gene names Cps1
Domain
Architecture

No domain graphic available

Description Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).
APC7_MOUSE
 
θ value 0.0563607 (rank : 12) NC score 0.079460 (rank : 14)
Query Neighborhood Hits 22 Target Neighborhood Hits 56 Shared Neighborhood Hits 4
SwissProt Accessions Q9WVM3, Q3UBM7, Q8BSR2, Q91W13 Gene names Anapc7, Apc7
Domain
Architecture
Description Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).
ODB2_HUMAN
 
θ value 0.813845 (rank : 13) NC score 0.076487 (rank : 15)
Query Neighborhood Hits 22 Target Neighborhood Hits 19 Shared Neighborhood Hits 6
SwissProt Accessions P11182 Gene names DBT, BCATE2
Domain
Architecture
Description Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).
APC7_HUMAN
 
θ value 1.38821 (rank : 14) NC score 0.056465 (rank : 18)
Query Neighborhood Hits 22 Target Neighborhood Hits 57 Shared Neighborhood Hits 4
SwissProt Accessions Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16 Gene names ANAPC7, APC7
Domain
Architecture
Description Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).
ODB2_MOUSE
 
θ value 1.38821 (rank : 15) NC score 0.071206 (rank : 16)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 6
SwissProt Accessions P53395 Gene names Dbt
Domain
Architecture
Description Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).
MP2K3_MOUSE
 
θ value 4.03905 (rank : 16) NC score 0.000878 (rank : 25)
Query Neighborhood Hits 22 Target Neighborhood Hits 826 Shared Neighborhood Hits 3
SwissProt Accessions O09110, P97293, Q91VX1 Gene names Map2k3, Mkk3, Prkmk3
Domain
Architecture
Description Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).
DEPD5_MOUSE
 
θ value 5.27518 (rank : 17) NC score 0.012575 (rank : 22)
Query Neighborhood Hits 22 Target Neighborhood Hits 32 Shared Neighborhood Hits 2
SwissProt Accessions P61460 Gene names Depdc5, Kiaa0645
Domain
Architecture
Description DEP domain-containing protein 5.
MP2K3_HUMAN
 
θ value 5.27518 (rank : 18) NC score 0.000669 (rank : 26)
Query Neighborhood Hits 22 Target Neighborhood Hits 825 Shared Neighborhood Hits 3
SwissProt Accessions P46734, Q99441, Q9UE71, Q9UE72 Gene names MAP2K3, MEK3, MKK3, PRKMK3
Domain
Architecture
Description Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).
PUR2_HUMAN
 
θ value 5.27518 (rank : 19) NC score 0.052629 (rank : 20)
Query Neighborhood Hits 22 Target Neighborhood Hits 21 Shared Neighborhood Hits 10
SwissProt Accessions P22102 Gene names GART, PRGS
Domain
Architecture
Description Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)].
PUR2_MOUSE
 
θ value 6.88961 (rank : 20) NC score 0.034090 (rank : 21)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 7
SwissProt Accessions Q64737, Q6NS48 Gene names Gart
Domain
Architecture
Description Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)].
RPB2_HUMAN
 
θ value 6.88961 (rank : 21) NC score 0.011912 (rank : 23)
Query Neighborhood Hits 22 Target Neighborhood Hits 22 Shared Neighborhood Hits 3
SwissProt Accessions P30876, Q8IZ61 Gene names POLR2B
Domain
Architecture
Description DNA-directed RNA polymerase II 140 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2) (RPB2).
RPB2_MOUSE
 
θ value 6.88961 (rank : 22) NC score 0.011909 (rank : 24)
Query Neighborhood Hits 22 Target Neighborhood Hits 22 Shared Neighborhood Hits 3
SwissProt Accessions Q8CFI7 Gene names Polr2b
Domain
Architecture

No domain graphic available

Description DNA-directed RNA polymerase II 140 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2) (RPB2).
HMGCL_HUMAN
 
θ value θ > 10 (rank : 23) NC score 0.054328 (rank : 19)
Query Neighborhood Hits 22 Target Neighborhood Hits 4 Shared Neighborhood Hits 2
SwissProt Accessions P35914, Q96FP8 Gene names HMGCL
Domain
Architecture
Description Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).
HMGCL_MOUSE
 
θ value θ > 10 (rank : 24) NC score 0.062165 (rank : 17)
Query Neighborhood Hits 22 Target Neighborhood Hits 4 Shared Neighborhood Hits 2
SwissProt Accessions P38060 Gene names Hmgcl
Domain
Architecture
Description Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).
PCCB_HUMAN
 
θ value θ > 10 (rank : 25) NC score 0.088069 (rank : 13)
Query Neighborhood Hits 22 Target Neighborhood Hits 8 Shared Neighborhood Hits 2
SwissProt Accessions P05166, Q16813 Gene names PCCB
Domain
Architecture
Description Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).
PCCB_MOUSE
 
θ value θ > 10 (rank : 26) NC score 0.090686 (rank : 12)
Query Neighborhood Hits 22 Target Neighborhood Hits 8 Shared Neighborhood Hits 2
SwissProt Accessions Q99MN9 Gene names Pccb
Domain
Architecture

No domain graphic available

Description Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

Hits sorted by NC score


PCCA_HUMAN
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 1)
Query Neighborhood Hits 22 Target Neighborhood Hits 22 Shared Neighborhood Hits 22
SwissProt Accessions P05165, Q15979 Gene names PCCA
Domain
Architecture
Description Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).
PCCA_MOUSE
 
NC score 0.999289 (rank : 2) θ value 0 (rank : 2)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 16
SwissProt Accessions Q91ZA3, Q80VU5, Q922N3 Gene names Pcca
Domain
Architecture

No domain graphic available

Description Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).
MCCA_MOUSE
 
NC score 0.967448 (rank : 3) θ value 6.19918e-134 (rank : 3)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 15
SwissProt Accessions Q99MR8, Q3TGU0, Q9D8R2 Gene names Mccc1, Mcca
Domain
Architecture
Description Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).
MCCA_HUMAN
 
NC score 0.966541 (rank : 4) θ value 4.44261e-132 (rank : 4)
Query Neighborhood Hits 22 Target Neighborhood Hits 26 Shared Neighborhood Hits 15
SwissProt Accessions Q96RQ3, Q59ES4, Q9H959, Q9NS97 Gene names MCCC1, MCCA
Domain
Architecture
Description Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).
PYC_HUMAN
 
NC score 0.930919 (rank : 5) θ value 1.34698e-104 (rank : 5)
Query Neighborhood Hits 22 Target Neighborhood Hits 25 Shared Neighborhood Hits 12
SwissProt Accessions P11498, Q16705 Gene names PC
Domain
Architecture
Description Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).
PYC_MOUSE
 
NC score 0.930753 (rank : 6) θ value 1.14028e-103 (rank : 6)
Query Neighborhood Hits 22 Target Neighborhood Hits 25 Shared Neighborhood Hits 11
SwissProt Accessions Q05920 Gene names Pc, Pcx
Domain
Architecture
Description Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).
COA1_HUMAN
 
NC score 0.824433 (rank : 7) θ value 4.84666e-62 (rank : 7)
Query Neighborhood Hits 22 Target Neighborhood Hits 49 Shared Neighborhood Hits 11
SwissProt Accessions Q13085 Gene names ACACA, ACAC, ACC1, ACCA
Domain
Architecture
Description Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].
COA2_HUMAN
 
NC score 0.790805 (rank : 8) θ value 2.10721e-57 (rank : 8)
Query Neighborhood Hits 22 Target Neighborhood Hits 184 Shared Neighborhood Hits 11
SwissProt Accessions O00763, Q16852 Gene names ACACB, ACC2, ACCB
Domain
Architecture
Description Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].
CPSM_MOUSE
 
NC score 0.399047 (rank : 9) θ value 1.99992e-07 (rank : 11)
Query Neighborhood Hits 22 Target Neighborhood Hits 32 Shared Neighborhood Hits 13
SwissProt Accessions Q8C196, Q6NX75 Gene names Cps1
Domain
Architecture

No domain graphic available

Description Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).
CPSM_HUMAN
 
NC score 0.394704 (rank : 10) θ value 8.97725e-08 (rank : 10)
Query Neighborhood Hits 22 Target Neighborhood Hits 27 Shared Neighborhood Hits 13
SwissProt Accessions P31327, O43774, Q7Z5I5 Gene names CPS1
Domain
Architecture
Description Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).
PYR1_HUMAN
 
NC score 0.392575 (rank : 11) θ value 9.59137e-10 (rank : 9)
Query Neighborhood Hits 22 Target Neighborhood Hits 119 Shared Neighborhood Hits 12
SwissProt Accessions P27708, Q6P0Q0 Gene names CAD
Domain
Architecture

No domain graphic available

Description CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].
PCCB_MOUSE
 
NC score 0.090686 (rank : 12) θ value θ > 10 (rank : 26)
Query Neighborhood Hits 22 Target Neighborhood Hits 8 Shared Neighborhood Hits 2
SwissProt Accessions Q99MN9 Gene names Pccb
Domain
Architecture

No domain graphic available

Description Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).
PCCB_HUMAN
 
NC score 0.088069 (rank : 13) θ value θ > 10 (rank : 25)
Query Neighborhood Hits 22 Target Neighborhood Hits 8 Shared Neighborhood Hits 2
SwissProt Accessions P05166, Q16813 Gene names PCCB
Domain
Architecture
Description Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).
APC7_MOUSE
 
NC score 0.079460 (rank : 14) θ value 0.0563607 (rank : 12)
Query Neighborhood Hits 22 Target Neighborhood Hits 56 Shared Neighborhood Hits 4
SwissProt Accessions Q9WVM3, Q3UBM7, Q8BSR2, Q91W13 Gene names Anapc7, Apc7
Domain
Architecture
Description Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).
ODB2_HUMAN
 
NC score 0.076487 (rank : 15) θ value 0.813845 (rank : 13)
Query Neighborhood Hits 22 Target Neighborhood Hits 19 Shared Neighborhood Hits 6
SwissProt Accessions P11182 Gene names DBT, BCATE2
Domain
Architecture
Description Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).
ODB2_MOUSE
 
NC score 0.071206 (rank : 16) θ value 1.38821 (rank : 15)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 6
SwissProt Accessions P53395 Gene names Dbt
Domain
Architecture
Description Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).
HMGCL_MOUSE
 
NC score 0.062165 (rank : 17) θ value θ > 10 (rank : 24)
Query Neighborhood Hits 22 Target Neighborhood Hits 4 Shared Neighborhood Hits 2
SwissProt Accessions P38060 Gene names Hmgcl
Domain
Architecture
Description Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).
APC7_HUMAN
 
NC score 0.056465 (rank : 18) θ value 1.38821 (rank : 14)
Query Neighborhood Hits 22 Target Neighborhood Hits 57 Shared Neighborhood Hits 4
SwissProt Accessions Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16 Gene names ANAPC7, APC7
Domain
Architecture
Description Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).
HMGCL_HUMAN
 
NC score 0.054328 (rank : 19) θ value θ > 10 (rank : 23)
Query Neighborhood Hits 22 Target Neighborhood Hits 4 Shared Neighborhood Hits 2
SwissProt Accessions P35914, Q96FP8 Gene names HMGCL
Domain
Architecture
Description Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).
PUR2_HUMAN
 
NC score 0.052629 (rank : 20) θ value 5.27518 (rank : 19)
Query Neighborhood Hits 22 Target Neighborhood Hits 21 Shared Neighborhood Hits 10
SwissProt Accessions P22102 Gene names GART, PRGS
Domain
Architecture
Description Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)].
PUR2_MOUSE
 
NC score 0.034090 (rank : 21) θ value 6.88961 (rank : 20)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 7
SwissProt Accessions Q64737, Q6NS48 Gene names Gart
Domain
Architecture
Description Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)].
DEPD5_MOUSE
 
NC score 0.012575 (rank : 22) θ value 5.27518 (rank : 17)
Query Neighborhood Hits 22 Target Neighborhood Hits 32 Shared Neighborhood Hits 2
SwissProt Accessions P61460 Gene names Depdc5, Kiaa0645
Domain
Architecture
Description DEP domain-containing protein 5.
RPB2_HUMAN
 
NC score 0.011912 (rank : 23) θ value 6.88961 (rank : 21)
Query Neighborhood Hits 22 Target Neighborhood Hits 22 Shared Neighborhood Hits 3
SwissProt Accessions P30876, Q8IZ61 Gene names POLR2B
Domain
Architecture
Description DNA-directed RNA polymerase II 140 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2) (RPB2).
RPB2_MOUSE
 
NC score 0.011909 (rank : 24) θ value 6.88961 (rank : 22)
Query Neighborhood Hits 22 Target Neighborhood Hits 22 Shared Neighborhood Hits 3
SwissProt Accessions Q8CFI7 Gene names Polr2b
Domain
Architecture

No domain graphic available

Description DNA-directed RNA polymerase II 140 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2) (RPB2).
MP2K3_MOUSE
 
NC score 0.000878 (rank : 25) θ value 4.03905 (rank : 16)
Query Neighborhood Hits 22 Target Neighborhood Hits 826 Shared Neighborhood Hits 3
SwissProt Accessions O09110, P97293, Q91VX1 Gene names Map2k3, Mkk3, Prkmk3
Domain
Architecture
Description Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).
MP2K3_HUMAN
 
NC score 0.000669 (rank : 26) θ value 5.27518 (rank : 18)
Query Neighborhood Hits 22 Target Neighborhood Hits 825 Shared Neighborhood Hits 3
SwissProt Accessions P46734, Q99441, Q9UE71, Q9UE72 Gene names MAP2K3, MEK3, MKK3, PRKMK3
Domain
Architecture
Description Dual specificity mitogen-activated protein kinase kinase 3 (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3).