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Network neighborhood for query Sequence : HMGCL_MOUSE

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HMGCL_MOUSE
SwissProt Accessions	P38060	Gene names	Hmgcl
Domain Architecture
Description	Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HMGCL_MOUSE
θ value	5.52945e-183 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	4	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P38060	Gene names	Hmgcl
Domain Architecture
Description	Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).

HMGCL_HUMAN
θ value	2.41524e-162 (rank : 2)	NC score	0.999401 (rank : 2)
Query Neighborhood Hits	4	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P35914, Q96FP8	Gene names	HMGCL
Domain Architecture
Description	Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).

PYC_MOUSE
θ value	0.00020696 (rank : 3)	NC score	0.172750 (rank : 3)
Query Neighborhood Hits	4	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q05920	Gene names	Pc, Pcx
Domain Architecture
Description	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).

PYC_HUMAN
θ value	0.00175202 (rank : 4)	NC score	0.160698 (rank : 4)
Query Neighborhood Hits	4	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P11498, Q16705	Gene names	PC
Domain Architecture
Description	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).

MCCA_HUMAN
θ value	θ > 10 (rank : 5)	NC score	0.062424 (rank : 5)
Query Neighborhood Hits	4	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RQ3, Q59ES4, Q9H959, Q9NS97	Gene names	MCCC1, MCCA
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

MCCA_MOUSE
θ value	θ > 10 (rank : 6)	NC score	0.061628 (rank : 8)
Query Neighborhood Hits	4	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MR8, Q3TGU0, Q9D8R2	Gene names	Mccc1, Mcca
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

PCCA_HUMAN
θ value	θ > 10 (rank : 7)	NC score	0.062165 (rank : 7)
Query Neighborhood Hits	4	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P05165, Q15979	Gene names	PCCA
Domain Architecture
Description	Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).

Hits sorted by NC score

HMGCL_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.52945e-183 (rank : 1)
Query Neighborhood Hits	4	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P38060	Gene names	Hmgcl
Domain Architecture
Description	Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).

HMGCL_HUMAN
NC score	0.999401 (rank : 2)	θ value	2.41524e-162 (rank : 2)
Query Neighborhood Hits	4	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P35914, Q96FP8	Gene names	HMGCL
Domain Architecture
Description	Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).

PYC_MOUSE
NC score	0.172750 (rank : 3)	θ value	0.00020696 (rank : 3)
Query Neighborhood Hits	4	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q05920	Gene names	Pc, Pcx
Domain Architecture
Description	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).

PYC_HUMAN
NC score	0.160698 (rank : 4)	θ value	0.00175202 (rank : 4)
Query Neighborhood Hits	4	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P11498, Q16705	Gene names	PC
Domain Architecture
Description	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).

MCCA_HUMAN
NC score	0.062424 (rank : 5)	θ value	θ > 10 (rank : 5)
Query Neighborhood Hits	4	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RQ3, Q59ES4, Q9H959, Q9NS97	Gene names	MCCC1, MCCA
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

PCCA_HUMAN
NC score	0.062165 (rank : 7)	θ value	θ > 10 (rank : 7)
Query Neighborhood Hits	4	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P05165, Q15979	Gene names	PCCA
Domain Architecture
Description	Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).

MCCA_MOUSE
NC score	0.061628 (rank : 8)	θ value	θ > 10 (rank : 6)
Query Neighborhood Hits	4	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MR8, Q3TGU0, Q9D8R2	Gene names	Mccc1, Mcca
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).