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Network neighborhood for query Sequence : TBX4_HUMAN

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TBX4_HUMAN
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBX4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	70	Target Neighborhood Hits	70	Shared Neighborhood Hits	70
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_MOUSE
θ value	0 (rank : 2)	NC score	0.998421 (rank : 2)
Query Neighborhood Hits	70	Target Neighborhood Hits	68	Shared Neighborhood Hits	49
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX5_HUMAN
θ value	5.05951e-144 (rank : 3)	NC score	0.991344 (rank : 3)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
θ value	6.60789e-144 (rank : 4)	NC score	0.990714 (rank : 4)
Query Neighborhood Hits	70	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX2_HUMAN
θ value	1.90147e-66 (rank : 5)	NC score	0.956078 (rank : 18)
Query Neighborhood Hits	70	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX2_MOUSE
θ value	1.90147e-66 (rank : 6)	NC score	0.961410 (rank : 13)
Query Neighborhood Hits	70	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX1_HUMAN
θ value	4.38363e-63 (rank : 7)	NC score	0.974029 (rank : 7)
Query Neighborhood Hits	70	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX20_MOUSE
θ value	4.38363e-63 (rank : 8)	NC score	0.978831 (rank : 5)
Query Neighborhood Hits	70	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX6_HUMAN
θ value	7.47731e-63 (rank : 9)	NC score	0.972438 (rank : 8)
Query Neighborhood Hits	70	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX3_HUMAN
θ value	9.76566e-63 (rank : 10)	NC score	0.953761 (rank : 20)
Query Neighborhood Hits	70	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX3_MOUSE
θ value	1.27544e-62 (rank : 11)	NC score	0.959439 (rank : 15)
Query Neighborhood Hits	70	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX1_MOUSE
θ value	2.84138e-62 (rank : 12)	NC score	0.974309 (rank : 6)
Query Neighborhood Hits	70	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX10_MOUSE
θ value	1.07972e-61 (rank : 13)	NC score	0.971289 (rank : 10)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX10_HUMAN
θ value	1.41016e-61 (rank : 14)	NC score	0.971751 (rank : 9)
Query Neighborhood Hits	70	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX6_MOUSE
θ value	1.84173e-61 (rank : 15)	NC score	0.969245 (rank : 11)
Query Neighborhood Hits	70	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX15_HUMAN
θ value	2.65945e-60 (rank : 16)	NC score	0.955922 (rank : 19)
Query Neighborhood Hits	70	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX18_HUMAN
θ value	5.92465e-60 (rank : 17)	NC score	0.953748 (rank : 21)
Query Neighborhood Hits	70	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX15_MOUSE
θ value	1.31987e-59 (rank : 18)	NC score	0.956081 (rank : 17)
Query Neighborhood Hits	70	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

TBX18_MOUSE
θ value	8.55514e-59 (rank : 19)	NC score	0.957480 (rank : 16)
Query Neighborhood Hits	70	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX21_HUMAN
θ value	6.34462e-54 (rank : 20)	NC score	0.944018 (rank : 27)
Query Neighborhood Hits	70	Target Neighborhood Hits	146	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX22_MOUSE
θ value	6.34462e-54 (rank : 21)	NC score	0.961311 (rank : 14)
Query Neighborhood Hits	70	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX22_HUMAN
θ value	7.01481e-53 (rank : 22)	NC score	0.961507 (rank : 12)
Query Neighborhood Hits	70	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX21_MOUSE
θ value	1.56274e-52 (rank : 23)	NC score	0.946670 (rank : 25)
Query Neighborhood Hits	70	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

BRAC_HUMAN
θ value	3.48141e-52 (rank : 24)	NC score	0.951258 (rank : 23)
Query Neighborhood Hits	70	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

BRAC_MOUSE
θ value	3.48141e-52 (rank : 25)	NC score	0.952726 (rank : 22)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBR1_HUMAN
θ value	1.788e-48 (rank : 26)	NC score	0.937535 (rank : 30)
Query Neighborhood Hits	70	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
θ value	1.788e-48 (rank : 27)	NC score	0.937567 (rank : 29)
Query Neighborhood Hits	70	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBX19_HUMAN
θ value	3.04986e-48 (rank : 28)	NC score	0.950360 (rank : 24)
Query Neighborhood Hits	70	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

EOMES_HUMAN
θ value	1.51363e-47 (rank : 29)	NC score	0.938954 (rank : 28)
Query Neighborhood Hits	70	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

EOMES_MOUSE
θ value	1.51363e-47 (rank : 30)	NC score	0.937459 (rank : 31)
Query Neighborhood Hits	70	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

TBX19_MOUSE
θ value	7.51208e-47 (rank : 31)	NC score	0.946115 (rank : 26)
Query Neighborhood Hits	70	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

AATK_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.004807 (rank : 57)
Query Neighborhood Hits	70	Target Neighborhood Hits	1243	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ENAH_MOUSE
θ value	0.21417 (rank : 33)	NC score	0.014360 (rank : 36)
Query Neighborhood Hits	70	Target Neighborhood Hits	919	Shared Neighborhood Hits	13
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

NOTC1_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.005031 (rank : 56)
Query Neighborhood Hits	70	Target Neighborhood Hits	916	Shared Neighborhood Hits	11
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.004203 (rank : 58)
Query Neighborhood Hits	70	Target Neighborhood Hits	1113	Shared Neighborhood Hits	15
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RERE_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.016355 (rank : 35)
Query Neighborhood Hits	70	Target Neighborhood Hits	779	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

KLF5_HUMAN
θ value	1.06291 (rank : 37)	NC score	-0.000198 (rank : 65)
Query Neighborhood Hits	70	Target Neighborhood Hits	727	Shared Neighborhood Hits	5
SwissProt Accessions	Q13887, Q9UHP8	Gene names	KLF5, BTEB2, CKLF, IKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 5 (Intestinal-enriched krueppel-like factor) (Colon krueppel-like factor) (Transcription factor BTEB2) (Basic transcription element-binding protein 2) (BTE-binding protein 2) (GC box-binding protein 2).

SOX7_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.013015 (rank : 39)
Query Neighborhood Hits	70	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

EP400_MOUSE
θ value	1.38821 (rank : 39)	NC score	0.006481 (rank : 53)
Query Neighborhood Hits	70	Target Neighborhood Hits	592	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

SLIK5_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.007190 (rank : 50)
Query Neighborhood Hits	70	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	O94991	Gene names	SLITRK5, KIAA0918, LRRC11
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor (Leucine-rich repeat-containing protein 11).

SLIK5_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.007230 (rank : 49)
Query Neighborhood Hits	70	Target Neighborhood Hits	301	Shared Neighborhood Hits	4
SwissProt Accessions	Q810B7, Q9CT21	Gene names	Slitrk5
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor.

WASF3_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.014184 (rank : 38)
Query Neighborhood Hits	70	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ACINU_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.014256 (rank : 37)
Query Neighborhood Hits	70	Target Neighborhood Hits	828	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SOX7_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.007952 (rank : 48)
Query Neighborhood Hits	70	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

PLEC1_HUMAN
θ value	3.0926 (rank : 45)	NC score	-0.002340 (rank : 68)
Query Neighborhood Hits	70	Target Neighborhood Hits	1326	Shared Neighborhood Hits	3
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

THAP4_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.009388 (rank : 44)
Query Neighborhood Hits	70	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

CLC14_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.008879 (rank : 45)
Query Neighborhood Hits	70	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

GGN_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.008459 (rank : 46)
Query Neighborhood Hits	70	Target Neighborhood Hits	311	Shared Neighborhood Hits	7
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

LTBP3_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.006514 (rank : 52)
Query Neighborhood Hits	70	Target Neighborhood Hits	475	Shared Neighborhood Hits	8
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC2_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.003503 (rank : 61)
Query Neighborhood Hits	70	Target Neighborhood Hits	1069	Shared Neighborhood Hits	14
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RERE_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.016571 (rank : 34)
Query Neighborhood Hits	70	Target Neighborhood Hits	785	Shared Neighborhood Hits	16
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ZCH14_MOUSE
θ value	4.03905 (rank : 52)	NC score	0.009638 (rank : 41)
Query Neighborhood Hits	70	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

FBX34_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.011708 (rank : 40)
Query Neighborhood Hits	70	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

INP4B_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.009471 (rank : 43)
Query Neighborhood Hits	70	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1Y8	Gene names	Inpp4b
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

TMPS9_HUMAN
θ value	5.27518 (rank : 55)	NC score	-0.000240 (rank : 66)
Query Neighborhood Hits	70	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TRI66_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.006400 (rank : 54)
Query Neighborhood Hits	70	Target Neighborhood Hits	479	Shared Neighborhood Hits	9
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

EHMT2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.001199 (rank : 63)
Query Neighborhood Hits	70	Target Neighborhood Hits	750	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MK07_HUMAN
θ value	6.88961 (rank : 58)	NC score	-0.003937 (rank : 70)
Query Neighborhood Hits	70	Target Neighborhood Hits	1087	Shared Neighborhood Hits	10
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

PHAR3_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.005083 (rank : 55)
Query Neighborhood Hits	70	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

WNK2_HUMAN
θ value	6.88961 (rank : 60)	NC score	-0.000690 (rank : 67)
Query Neighborhood Hits	70	Target Neighborhood Hits	1407	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK3_HUMAN
θ value	6.88961 (rank : 61)	NC score	-0.003297 (rank : 69)
Query Neighborhood Hits	70	Target Neighborhood Hits	948	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

AAKB2_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.029903 (rank : 32)
Query Neighborhood Hits	70	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	O43741, Q5VXY0	Gene names	PRKAB2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

AAKB2_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.025398 (rank : 33)
Query Neighborhood Hits	70	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PAM0	Gene names	Prkab2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

FGD1_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.000738 (rank : 64)
Query Neighborhood Hits	70	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

G3BP2_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.004012 (rank : 60)
Query Neighborhood Hits	70	Target Neighborhood Hits	260	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

G3BP2_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.004054 (rank : 59)
Query Neighborhood Hits	70	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

GNRP_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.001661 (rank : 62)
Query Neighborhood Hits	70	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

LSR_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.009519 (rank : 42)
Query Neighborhood Hits	70	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KG5, Q3TJE7, Q3UIQ9, Q61148, Q61149, Q6U816	Gene names	Lsr, Lisch7
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor precursor (Liver-specific bHLH-Zip transcription factor) (Lipolysis-stimulated receptor) (Liver- specific gene on mouse chromosome 7 protein).

NPAS4_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.006671 (rank : 51)
Query Neighborhood Hits	70	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NUFP1_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.008366 (rank : 47)
Query Neighborhood Hits	70	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

Hits sorted by NC score

TBX4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	70	Target Neighborhood Hits	70	Shared Neighborhood Hits	70
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_MOUSE
NC score	0.998421 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	70	Target Neighborhood Hits	68	Shared Neighborhood Hits	49
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX5_HUMAN
NC score	0.991344 (rank : 3)	θ value	5.05951e-144 (rank : 3)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
NC score	0.990714 (rank : 4)	θ value	6.60789e-144 (rank : 4)
Query Neighborhood Hits	70	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX20_MOUSE
NC score	0.978831 (rank : 5)	θ value	4.38363e-63 (rank : 8)
Query Neighborhood Hits	70	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX1_MOUSE
NC score	0.974309 (rank : 6)	θ value	2.84138e-62 (rank : 12)
Query Neighborhood Hits	70	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX1_HUMAN
NC score	0.974029 (rank : 7)	θ value	4.38363e-63 (rank : 7)
Query Neighborhood Hits	70	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX6_HUMAN
NC score	0.972438 (rank : 8)	θ value	7.47731e-63 (rank : 9)
Query Neighborhood Hits	70	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX10_HUMAN
NC score	0.971751 (rank : 9)	θ value	1.41016e-61 (rank : 14)
Query Neighborhood Hits	70	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX10_MOUSE
NC score	0.971289 (rank : 10)	θ value	1.07972e-61 (rank : 13)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX6_MOUSE
NC score	0.969245 (rank : 11)	θ value	1.84173e-61 (rank : 15)
Query Neighborhood Hits	70	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX22_HUMAN
NC score	0.961507 (rank : 12)	θ value	7.01481e-53 (rank : 22)
Query Neighborhood Hits	70	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX2_MOUSE
NC score	0.961410 (rank : 13)	θ value	1.90147e-66 (rank : 6)
Query Neighborhood Hits	70	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX22_MOUSE
NC score	0.961311 (rank : 14)	θ value	6.34462e-54 (rank : 21)
Query Neighborhood Hits	70	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX3_MOUSE
NC score	0.959439 (rank : 15)	θ value	1.27544e-62 (rank : 11)
Query Neighborhood Hits	70	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX18_MOUSE
NC score	0.957480 (rank : 16)	θ value	8.55514e-59 (rank : 19)
Query Neighborhood Hits	70	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX15_MOUSE
NC score	0.956081 (rank : 17)	θ value	1.31987e-59 (rank : 18)
Query Neighborhood Hits	70	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

TBX2_HUMAN
NC score	0.956078 (rank : 18)	θ value	1.90147e-66 (rank : 5)
Query Neighborhood Hits	70	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX15_HUMAN
NC score	0.955922 (rank : 19)	θ value	2.65945e-60 (rank : 16)
Query Neighborhood Hits	70	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX3_HUMAN
NC score	0.953761 (rank : 20)	θ value	9.76566e-63 (rank : 10)
Query Neighborhood Hits	70	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX18_HUMAN
NC score	0.953748 (rank : 21)	θ value	5.92465e-60 (rank : 17)
Query Neighborhood Hits	70	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

BRAC_MOUSE
NC score	0.952726 (rank : 22)	θ value	3.48141e-52 (rank : 25)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

BRAC_HUMAN
NC score	0.951258 (rank : 23)	θ value	3.48141e-52 (rank : 24)
Query Neighborhood Hits	70	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX19_HUMAN
NC score	0.950360 (rank : 24)	θ value	3.04986e-48 (rank : 28)
Query Neighborhood Hits	70	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX21_MOUSE
NC score	0.946670 (rank : 25)	θ value	1.56274e-52 (rank : 23)
Query Neighborhood Hits	70	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX19_MOUSE
NC score	0.946115 (rank : 26)	θ value	7.51208e-47 (rank : 31)
Query Neighborhood Hits	70	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX21_HUMAN
NC score	0.944018 (rank : 27)	θ value	6.34462e-54 (rank : 20)
Query Neighborhood Hits	70	Target Neighborhood Hits	146	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

EOMES_HUMAN
NC score	0.938954 (rank : 28)	θ value	1.51363e-47 (rank : 29)
Query Neighborhood Hits	70	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

TBR1_MOUSE
NC score	0.937567 (rank : 29)	θ value	1.788e-48 (rank : 27)
Query Neighborhood Hits	70	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_HUMAN
NC score	0.937535 (rank : 30)	θ value	1.788e-48 (rank : 26)
Query Neighborhood Hits	70	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

EOMES_MOUSE
NC score	0.937459 (rank : 31)	θ value	1.51363e-47 (rank : 30)
Query Neighborhood Hits	70	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

AAKB2_HUMAN
NC score	0.029903 (rank : 32)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	70	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	O43741, Q5VXY0	Gene names	PRKAB2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

AAKB2_MOUSE
NC score	0.025398 (rank : 33)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	70	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PAM0	Gene names	Prkab2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

RERE_MOUSE
NC score	0.016571 (rank : 34)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	70	Target Neighborhood Hits	785	Shared Neighborhood Hits	16
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RERE_HUMAN
NC score	0.016355 (rank : 35)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	70	Target Neighborhood Hits	779	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

ENAH_MOUSE
NC score	0.014360 (rank : 36)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	70	Target Neighborhood Hits	919	Shared Neighborhood Hits	13
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ACINU_HUMAN
NC score	0.014256 (rank : 37)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	70	Target Neighborhood Hits	828	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

WASF3_MOUSE
NC score	0.014184 (rank : 38)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	70	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

SOX7_MOUSE
NC score	0.013015 (rank : 39)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	70	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

FBX34_HUMAN
NC score	0.011708 (rank : 40)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	70	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

ZCH14_MOUSE
NC score	0.009638 (rank : 41)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	70	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

LSR_MOUSE
NC score	0.009519 (rank : 42)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	70	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KG5, Q3TJE7, Q3UIQ9, Q61148, Q61149, Q6U816	Gene names	Lsr, Lisch7
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor precursor (Liver-specific bHLH-Zip transcription factor) (Lipolysis-stimulated receptor) (Liver- specific gene on mouse chromosome 7 protein).

INP4B_MOUSE
NC score	0.009471 (rank : 43)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	70	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1Y8	Gene names	Inpp4b
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

THAP4_MOUSE
NC score	0.009388 (rank : 44)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	70	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

CLC14_HUMAN
NC score	0.008879 (rank : 45)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	70	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

GGN_MOUSE
NC score	0.008459 (rank : 46)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	70	Target Neighborhood Hits	311	Shared Neighborhood Hits	7
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

NUFP1_HUMAN
NC score	0.008366 (rank : 47)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	70	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

SOX7_HUMAN
NC score	0.007952 (rank : 48)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	70	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SLIK5_MOUSE
NC score	0.007230 (rank : 49)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	70	Target Neighborhood Hits	301	Shared Neighborhood Hits	4
SwissProt Accessions	Q810B7, Q9CT21	Gene names	Slitrk5
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor.

SLIK5_HUMAN
NC score	0.007190 (rank : 50)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	70	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	O94991	Gene names	SLITRK5, KIAA0918, LRRC11
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor (Leucine-rich repeat-containing protein 11).

NPAS4_HUMAN
NC score	0.006671 (rank : 51)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	70	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

LTBP3_MOUSE
NC score	0.006514 (rank : 52)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	70	Target Neighborhood Hits	475	Shared Neighborhood Hits	8
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

EP400_MOUSE
NC score	0.006481 (rank : 53)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	70	Target Neighborhood Hits	592	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

TRI66_HUMAN
NC score	0.006400 (rank : 54)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	70	Target Neighborhood Hits	479	Shared Neighborhood Hits	9
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PHAR3_HUMAN
NC score	0.005083 (rank : 55)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	70	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

NOTC1_MOUSE
NC score	0.005031 (rank : 56)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	70	Target Neighborhood Hits	916	Shared Neighborhood Hits	11
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

AATK_HUMAN
NC score	0.004807 (rank : 57)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	70	Target Neighborhood Hits	1243	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

NOTC2_HUMAN
NC score	0.004203 (rank : 58)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	70	Target Neighborhood Hits	1113	Shared Neighborhood Hits	15
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

G3BP2_MOUSE
NC score	0.004054 (rank : 59)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	70	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

G3BP2_HUMAN
NC score	0.004012 (rank : 60)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	70	Target Neighborhood Hits	260	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

NOTC2_MOUSE
NC score	0.003503 (rank : 61)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	70	Target Neighborhood Hits	1069	Shared Neighborhood Hits	14
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

GNRP_HUMAN
NC score	0.001661 (rank : 62)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	70	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

EHMT2_MOUSE
NC score	0.001199 (rank : 63)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	70	Target Neighborhood Hits	750	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FGD1_MOUSE
NC score	0.000738 (rank : 64)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	70	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

KLF5_HUMAN
NC score	-0.000198 (rank : 65)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	70	Target Neighborhood Hits	727	Shared Neighborhood Hits	5
SwissProt Accessions	Q13887, Q9UHP8	Gene names	KLF5, BTEB2, CKLF, IKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 5 (Intestinal-enriched krueppel-like factor) (Colon krueppel-like factor) (Transcription factor BTEB2) (Basic transcription element-binding protein 2) (BTE-binding protein 2) (GC box-binding protein 2).

TMPS9_HUMAN
NC score	-0.000240 (rank : 66)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	70	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

WNK2_HUMAN
NC score	-0.000690 (rank : 67)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	70	Target Neighborhood Hits	1407	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

PLEC1_HUMAN
NC score	-0.002340 (rank : 68)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	70	Target Neighborhood Hits	1326	Shared Neighborhood Hits	3
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

WNK3_HUMAN
NC score	-0.003297 (rank : 69)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	70	Target Neighborhood Hits	948	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

MK07_HUMAN
NC score	-0.003937 (rank : 70)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	70	Target Neighborhood Hits	1087	Shared Neighborhood Hits	10
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).