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Network neighborhood for query Sequence : TBX5_HUMAN

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TBX5_HUMAN
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBX5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
θ value	0 (rank : 2)	NC score	0.998874 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	61	Shared Neighborhood Hits	44
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX4_MOUSE
θ value	9.85132e-148 (rank : 3)	NC score	0.991422 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_HUMAN
θ value	5.05951e-144 (rank : 4)	NC score	0.991344 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX2_HUMAN
θ value	2.74572e-65 (rank : 5)	NC score	0.956458 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX2_MOUSE
θ value	2.74572e-65 (rank : 6)	NC score	0.961727 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX6_HUMAN
θ value	2.56992e-63 (rank : 7)	NC score	0.973422 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX20_MOUSE
θ value	1.27544e-62 (rank : 8)	NC score	0.979352 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX1_HUMAN
θ value	1.66577e-62 (rank : 9)	NC score	0.974355 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX3_HUMAN
θ value	8.26713e-62 (rank : 10)	NC score	0.954144 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX6_MOUSE
θ value	1.41016e-61 (rank : 11)	NC score	0.970134 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX3_MOUSE
θ value	2.40537e-61 (rank : 12)	NC score	0.959691 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX1_MOUSE
θ value	3.14151e-61 (rank : 13)	NC score	0.974366 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX10_HUMAN
θ value	2.03627e-60 (rank : 14)	NC score	0.971917 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX10_MOUSE
θ value	4.53632e-60 (rank : 15)	NC score	0.971509 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX18_HUMAN
θ value	2.25136e-59 (rank : 16)	NC score	0.954063 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX18_MOUSE
θ value	1.90589e-58 (rank : 17)	NC score	0.957674 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX15_HUMAN
θ value	3.25095e-58 (rank : 18)	NC score	0.955858 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX15_MOUSE
θ value	3.25095e-58 (rank : 19)	NC score	0.956021 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

BRAC_MOUSE
θ value	1.84601e-53 (rank : 20)	NC score	0.954184 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

BRAC_HUMAN
θ value	4.54686e-52 (rank : 21)	NC score	0.952648 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX22_MOUSE
θ value	5.93839e-52 (rank : 22)	NC score	0.961160 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX21_HUMAN
θ value	2.94719e-51 (rank : 23)	NC score	0.943910 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX21_MOUSE
θ value	1.91031e-50 (rank : 24)	NC score	0.946816 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	116	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX22_HUMAN
θ value	2.49495e-50 (rank : 25)	NC score	0.961179 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBR1_HUMAN
θ value	3.2585e-50 (rank : 26)	NC score	0.939718 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
θ value	3.2585e-50 (rank : 27)	NC score	0.939708 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

EOMES_HUMAN
θ value	2.3352e-48 (rank : 28)	NC score	0.940821 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

EOMES_MOUSE
θ value	2.3352e-48 (rank : 29)	NC score	0.939324 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

TBX19_HUMAN
θ value	3.98324e-48 (rank : 30)	NC score	0.951401 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX19_MOUSE
θ value	1.28137e-46 (rank : 31)	NC score	0.947287 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

CI079_HUMAN
θ value	0.0431538 (rank : 32)	NC score	0.033881 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

AAKB2_HUMAN
θ value	0.163984 (rank : 33)	NC score	0.046314 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	O43741, Q5VXY0	Gene names	PRKAB2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

AAKB2_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.040691 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PAM0	Gene names	Prkab2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

FOXN4_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.012321 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	248	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

FBXL4_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.026128 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

SF3A3_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.030845 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q12874, Q15460	Gene names	SF3A3, SAP61
Domain Architecture	No domain graphic available
Description	Splicing factor 3A subunit 3 (Spliceosome-associated protein 61) (SAP 61) (SF3a60).

SF3A3_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.030934 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D554	Gene names	Sf3a3, Sap61
Domain Architecture	No domain graphic available
Description	Splicing factor 3A subunit 3 (Spliceosome-associated protein 61) (SAP 61) (SF3a60).

FOXP4_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.012563 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

CXA1_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.004948 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P17302, Q9Y5I8	Gene names	GJA1, GJAL
Domain Architecture
Description	Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein).

FOXP4_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.006738 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	211	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

TAB3_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.008741 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

BMP2K_HUMAN
θ value	6.88961 (rank : 43)	NC score	-0.001761 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	867	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

PER2_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.004399 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

U2AFL_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.007312 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	389	Shared Neighborhood Hits	3
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

EMX2_HUMAN
θ value	8.99809 (rank : 46)	NC score	-0.001422 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	341	Shared Neighborhood Hits	2
SwissProt Accessions	Q04743, Q96NN8, Q9BQF4	Gene names	EMX2
Domain Architecture
Description	Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty spiracles- like protein 2).

SYNP2_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.004323 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

Hits sorted by NC score

TBX5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
NC score	0.998874 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	61	Shared Neighborhood Hits	44
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX4_MOUSE
NC score	0.991422 (rank : 3)	θ value	9.85132e-148 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_HUMAN
NC score	0.991344 (rank : 4)	θ value	5.05951e-144 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX20_MOUSE
NC score	0.979352 (rank : 5)	θ value	1.27544e-62 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX1_MOUSE
NC score	0.974366 (rank : 6)	θ value	3.14151e-61 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX1_HUMAN
NC score	0.974355 (rank : 7)	θ value	1.66577e-62 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX6_HUMAN
NC score	0.973422 (rank : 8)	θ value	2.56992e-63 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX10_HUMAN
NC score	0.971917 (rank : 9)	θ value	2.03627e-60 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX10_MOUSE
NC score	0.971509 (rank : 10)	θ value	4.53632e-60 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX6_MOUSE
NC score	0.970134 (rank : 11)	θ value	1.41016e-61 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX2_MOUSE
NC score	0.961727 (rank : 12)	θ value	2.74572e-65 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX22_HUMAN
NC score	0.961179 (rank : 13)	θ value	2.49495e-50 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX22_MOUSE
NC score	0.961160 (rank : 14)	θ value	5.93839e-52 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX3_MOUSE
NC score	0.959691 (rank : 15)	θ value	2.40537e-61 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX18_MOUSE
NC score	0.957674 (rank : 16)	θ value	1.90589e-58 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX2_HUMAN
NC score	0.956458 (rank : 17)	θ value	2.74572e-65 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX15_MOUSE
NC score	0.956021 (rank : 18)	θ value	3.25095e-58 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

TBX15_HUMAN
NC score	0.955858 (rank : 19)	θ value	3.25095e-58 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

BRAC_MOUSE
NC score	0.954184 (rank : 20)	θ value	1.84601e-53 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX3_HUMAN
NC score	0.954144 (rank : 21)	θ value	8.26713e-62 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX18_HUMAN
NC score	0.954063 (rank : 22)	θ value	2.25136e-59 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

BRAC_HUMAN
NC score	0.952648 (rank : 23)	θ value	4.54686e-52 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX19_HUMAN
NC score	0.951401 (rank : 24)	θ value	3.98324e-48 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX19_MOUSE
NC score	0.947287 (rank : 25)	θ value	1.28137e-46 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX21_MOUSE
NC score	0.946816 (rank : 26)	θ value	1.91031e-50 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	116	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX21_HUMAN
NC score	0.943910 (rank : 27)	θ value	2.94719e-51 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

EOMES_HUMAN
NC score	0.940821 (rank : 28)	θ value	2.3352e-48 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

TBR1_HUMAN
NC score	0.939718 (rank : 29)	θ value	3.2585e-50 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
NC score	0.939708 (rank : 30)	θ value	3.2585e-50 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

EOMES_MOUSE
NC score	0.939324 (rank : 31)	θ value	2.3352e-48 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

AAKB2_HUMAN
NC score	0.046314 (rank : 32)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	O43741, Q5VXY0	Gene names	PRKAB2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

AAKB2_MOUSE
NC score	0.040691 (rank : 33)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PAM0	Gene names	Prkab2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit beta-2 (AMPK beta-2 chain).

CI079_HUMAN
NC score	0.033881 (rank : 34)	θ value	0.0431538 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

SF3A3_MOUSE
NC score	0.030934 (rank : 35)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D554	Gene names	Sf3a3, Sap61
Domain Architecture	No domain graphic available
Description	Splicing factor 3A subunit 3 (Spliceosome-associated protein 61) (SAP 61) (SF3a60).

SF3A3_HUMAN
NC score	0.030845 (rank : 36)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q12874, Q15460	Gene names	SF3A3, SAP61
Domain Architecture	No domain graphic available
Description	Splicing factor 3A subunit 3 (Spliceosome-associated protein 61) (SAP 61) (SF3a60).

FBXL4_HUMAN
NC score	0.026128 (rank : 37)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

FOXP4_HUMAN
NC score	0.012563 (rank : 38)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

FOXN4_HUMAN
NC score	0.012321 (rank : 39)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	248	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

TAB3_MOUSE
NC score	0.008741 (rank : 40)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

U2AFL_MOUSE
NC score	0.007312 (rank : 41)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	389	Shared Neighborhood Hits	3
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

FOXP4_MOUSE
NC score	0.006738 (rank : 42)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	211	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

CXA1_HUMAN
NC score	0.004948 (rank : 43)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P17302, Q9Y5I8	Gene names	GJA1, GJAL
Domain Architecture
Description	Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein).

PER2_MOUSE
NC score	0.004399 (rank : 44)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

SYNP2_HUMAN
NC score	0.004323 (rank : 45)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

EMX2_HUMAN
NC score	-0.001422 (rank : 46)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	341	Shared Neighborhood Hits	2
SwissProt Accessions	Q04743, Q96NN8, Q9BQF4	Gene names	EMX2
Domain Architecture
Description	Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty spiracles- like protein 2).

BMP2K_HUMAN
NC score	-0.001761 (rank : 47)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	867	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).