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Network neighborhood for query Sequence : LSR_MOUSE

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LSR_MOUSE
SwissProt Accessions	Q99KG5, Q3TJE7, Q3UIQ9, Q61148, Q61149, Q6U816	Gene names	Lsr, Lisch7
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor precursor (Liver-specific bHLH-Zip transcription factor) (Lipolysis-stimulated receptor) (Liver- specific gene on mouse chromosome 7 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LSR_HUMAN
θ value	0 (rank : 1)	NC score	0.983501 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

LSR_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q99KG5, Q3TJE7, Q3UIQ9, Q61148, Q61149, Q6U816	Gene names	Lsr, Lisch7
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor precursor (Liver-specific bHLH-Zip transcription factor) (Lipolysis-stimulated receptor) (Liver- specific gene on mouse chromosome 7 protein).

ILDR1_MOUSE
θ value	2.20094e-22 (rank : 3)	NC score	0.676245 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CBR1, Q6PFB3, Q8CB39, Q91VS0	Gene names	Ildr1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

ILDR1_HUMAN
θ value	1.42661e-21 (rank : 4)	NC score	0.673558 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

GPA33_HUMAN
θ value	0.00509761 (rank : 5)	NC score	0.126347 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	273	Shared Neighborhood Hits	12
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

RU17_HUMAN
θ value	0.125558 (rank : 6)	NC score	0.055828 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	280	Shared Neighborhood Hits	3
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

RU17_MOUSE
θ value	0.125558 (rank : 7)	NC score	0.056172 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	278	Shared Neighborhood Hits	3
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

SDK2_HUMAN
θ value	0.163984 (rank : 8)	NC score	0.032627 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	495	Shared Neighborhood Hits	10
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

CAC1G_HUMAN
θ value	0.21417 (rank : 9)	NC score	0.034003 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	587	Shared Neighborhood Hits	6
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SPRL1_MOUSE
θ value	0.21417 (rank : 10)	NC score	0.040767 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

LAD1_HUMAN
θ value	0.279714 (rank : 11)	NC score	0.042588 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	441	Shared Neighborhood Hits	3
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

GPA33_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.080547 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

SDK2_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.031919 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	480	Shared Neighborhood Hits	10
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

ES8L1_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.028786 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

GASP2_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.061566 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

LYRIC_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.055679 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

ZO1_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.028258 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	453	Shared Neighborhood Hits	7
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

MCSP_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.114832 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

CI066_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.100685 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T8R8, Q96NB0	Gene names	C9orf66
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf66.

GASP2_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.041130 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q96D09, Q8NAB4	Gene names	GPRASP2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

GRN_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.040301 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	268	Shared Neighborhood Hits	8
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

IP3KC_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.032663 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

TACC3_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.017002 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	779	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

LRCH4_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.010478 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	302	Shared Neighborhood Hits	3
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

MDC1_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.014754 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	1446	Shared Neighborhood Hits	10
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PRRT3_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.021224 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	998	Shared Neighborhood Hits	7
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

VCAM1_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.038920 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	320	Shared Neighborhood Hits	10
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

GRN_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.035163 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	248	Shared Neighborhood Hits	8
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

TIMD2_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.036577 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R183, Q8VBW0	Gene names	Timd2, Tim2
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 2 precursor (TIMD-2) (T cell membrane protein 2) (TIM-2).

VCAM1_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.032724 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	352	Shared Neighborhood Hits	10
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

PGBM_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.013196 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	1113	Shared Neighborhood Hits	12
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

HTRA3_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.012520 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

TBX4_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.010159 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

KRA24_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.016543 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

NRG1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.016613 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

TBX4_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.009519 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

WNK3_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.000615 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	948	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

Hits sorted by NC score

LSR_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q99KG5, Q3TJE7, Q3UIQ9, Q61148, Q61149, Q6U816	Gene names	Lsr, Lisch7
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor precursor (Liver-specific bHLH-Zip transcription factor) (Lipolysis-stimulated receptor) (Liver- specific gene on mouse chromosome 7 protein).

LSR_HUMAN
NC score	0.983501 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

ILDR1_MOUSE
NC score	0.676245 (rank : 3)	θ value	2.20094e-22 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CBR1, Q6PFB3, Q8CB39, Q91VS0	Gene names	Ildr1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

ILDR1_HUMAN
NC score	0.673558 (rank : 4)	θ value	1.42661e-21 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

GPA33_HUMAN
NC score	0.126347 (rank : 5)	θ value	0.00509761 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	273	Shared Neighborhood Hits	12
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

MCSP_HUMAN
NC score	0.114832 (rank : 6)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

CI066_HUMAN
NC score	0.100685 (rank : 7)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T8R8, Q96NB0	Gene names	C9orf66
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf66.

GPA33_MOUSE
NC score	0.080547 (rank : 8)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

GASP2_MOUSE
NC score	0.061566 (rank : 9)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

RU17_MOUSE
NC score	0.056172 (rank : 10)	θ value	0.125558 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	278	Shared Neighborhood Hits	3
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

RU17_HUMAN
NC score	0.055828 (rank : 11)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	280	Shared Neighborhood Hits	3
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

LYRIC_HUMAN
NC score	0.055679 (rank : 12)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

LAD1_HUMAN
NC score	0.042588 (rank : 13)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	441	Shared Neighborhood Hits	3
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

GASP2_HUMAN
NC score	0.041130 (rank : 14)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q96D09, Q8NAB4	Gene names	GPRASP2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

SPRL1_MOUSE
NC score	0.040767 (rank : 15)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

GRN_HUMAN
NC score	0.040301 (rank : 16)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	268	Shared Neighborhood Hits	8
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

VCAM1_MOUSE
NC score	0.038920 (rank : 17)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	320	Shared Neighborhood Hits	10
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

TIMD2_MOUSE
NC score	0.036577 (rank : 18)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R183, Q8VBW0	Gene names	Timd2, Tim2
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 2 precursor (TIMD-2) (T cell membrane protein 2) (TIM-2).

GRN_MOUSE
NC score	0.035163 (rank : 19)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	248	Shared Neighborhood Hits	8
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

CAC1G_HUMAN
NC score	0.034003 (rank : 20)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	587	Shared Neighborhood Hits	6
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

VCAM1_HUMAN
NC score	0.032724 (rank : 21)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	352	Shared Neighborhood Hits	10
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

IP3KC_MOUSE
NC score	0.032663 (rank : 22)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

SDK2_HUMAN
NC score	0.032627 (rank : 23)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	495	Shared Neighborhood Hits	10
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
NC score	0.031919 (rank : 24)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	480	Shared Neighborhood Hits	10
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

ES8L1_HUMAN
NC score	0.028786 (rank : 25)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ZO1_MOUSE
NC score	0.028258 (rank : 26)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	453	Shared Neighborhood Hits	7
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

PRRT3_HUMAN
NC score	0.021224 (rank : 27)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	998	Shared Neighborhood Hits	7
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TACC3_HUMAN
NC score	0.017002 (rank : 28)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	779	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

NRG1_HUMAN
NC score	0.016613 (rank : 29)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

KRA24_HUMAN
NC score	0.016543 (rank : 30)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

MDC1_HUMAN
NC score	0.014754 (rank : 31)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	1446	Shared Neighborhood Hits	10
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PGBM_HUMAN
NC score	0.013196 (rank : 32)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	1113	Shared Neighborhood Hits	12
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

HTRA3_MOUSE
NC score	0.012520 (rank : 33)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

LRCH4_MOUSE
NC score	0.010478 (rank : 34)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	302	Shared Neighborhood Hits	3
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

TBX4_MOUSE
NC score	0.010159 (rank : 35)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_HUMAN
NC score	0.009519 (rank : 36)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

WNK3_HUMAN
NC score	0.000615 (rank : 37)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	948	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).