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Network neighborhood for query Sequence : ARRD1_MOUSE

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ARRD1_MOUSE
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARRD1_HUMAN
θ value	0 (rank : 1)	NC score	0.973047 (rank : 2)
Query Neighborhood Hits	90	Target Neighborhood Hits	75	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ARRD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	90
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ARRD2_MOUSE
θ value	2.35151e-24 (rank : 3)	NC score	0.752109 (rank : 3)
Query Neighborhood Hits	90	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D668, Q3UVK8, Q3UXC6	Gene names	Arrdc2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ARRD2_HUMAN
θ value	8.93572e-24 (rank : 4)	NC score	0.743817 (rank : 4)
Query Neighborhood Hits	90	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TBH0, O95895, Q6ZRV9, Q8WYG6	Gene names	ARRDC2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ARRD4_HUMAN
θ value	1.2077e-20 (rank : 5)	NC score	0.734026 (rank : 5)
Query Neighborhood Hits	90	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NCT1, Q6NSI9	Gene names	ARRDC4
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 4.

ARRD3_HUMAN
θ value	2.27762e-19 (rank : 6)	NC score	0.719368 (rank : 7)
Query Neighborhood Hits	90	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q96B67, Q9P2H1	Gene names	ARRDC3, KIAA1376
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 3.

ARRD3_MOUSE
θ value	2.27762e-19 (rank : 7)	NC score	0.721970 (rank : 6)
Query Neighborhood Hits	90	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TPQ9, Q4KMN0, Q80TE6, Q8K0L7	Gene names	Arrdc3, Kiaa1376
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 3.

TXNIP_HUMAN
θ value	4.74913e-17 (rank : 8)	NC score	0.698244 (rank : 8)
Query Neighborhood Hits	90	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3M7, Q16226, Q6PML0, Q9BXG9	Gene names	TXNIP, VDUP1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1) (Thioredoxin-binding protein 2).

TXNIP_MOUSE
θ value	1.80466e-16 (rank : 9)	NC score	0.695192 (rank : 9)
Query Neighborhood Hits	90	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BG60, Q8BGQ0, Q8K2B2, Q9DC00, Q9EP90, Q9R115	Gene names	Txnip, Vdup1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1).

ARRD5_MOUSE
θ value	7.59969e-07 (rank : 10)	NC score	0.516707 (rank : 10)
Query Neighborhood Hits	90	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q497K5	Gene names	Arrdc5
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 5.

MLL2_HUMAN
θ value	0.00509761 (rank : 11)	NC score	0.055026 (rank : 18)
Query Neighborhood Hits	90	Target Neighborhood Hits	1788	Shared Neighborhood Hits	40
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

DSCR3_HUMAN
θ value	0.0330416 (rank : 12)	NC score	0.143639 (rank : 12)
Query Neighborhood Hits	90	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O14972	Gene names	DSCR3, DCRA, DSCRA
Domain Architecture
Description	Down syndrome critical region protein 3 (Down syndrome critical region protein A).

ARRB2_HUMAN
θ value	0.0431538 (rank : 13)	NC score	0.104272 (rank : 13)
Query Neighborhood Hits	90	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	P32121, Q0Z8D3, Q2PP19, Q6ICT3, Q8N7Y2, Q9UEQ6	Gene names	ARRB2, ARB2, ARR2
Domain Architecture
Description	Beta-arrestin-2 (Arrestin beta 2).

DSCR3_MOUSE
θ value	0.0431538 (rank : 14)	NC score	0.146164 (rank : 11)
Query Neighborhood Hits	90	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O35075, Q542V5	Gene names	Dscr3, Dcra, Dscra
Domain Architecture
Description	Down syndrome critical region protein 3 homolog (Down syndrome critical region protein A homolog).

K1802_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.035832 (rank : 33)
Query Neighborhood Hits	90	Target Neighborhood Hits	1378	Shared Neighborhood Hits	40
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CSKI1_HUMAN
θ value	0.125558 (rank : 16)	NC score	0.032053 (rank : 41)
Query Neighborhood Hits	90	Target Neighborhood Hits	997	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ATN1_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.054237 (rank : 19)
Query Neighborhood Hits	90	Target Neighborhood Hits	676	Shared Neighborhood Hits	24
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

TBR1_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.034899 (rank : 34)
Query Neighborhood Hits	90	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

ARRB1_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.102933 (rank : 14)
Query Neighborhood Hits	90	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P49407, O75625, O75630, Q2PP20, Q9BTK8	Gene names	ARRB1, ARR1
Domain Architecture
Description	Beta-arrestin-1 (Arrestin beta 1).

ARRB2_MOUSE
θ value	0.21417 (rank : 20)	NC score	0.094586 (rank : 15)
Query Neighborhood Hits	90	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YI4, Q3TCM2, Q5F2D8, Q5F2E0	Gene names	Arrb2
Domain Architecture
Description	Beta-arrestin-2 (Arrestin beta 2).

TBR1_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.033948 (rank : 37)
Query Neighborhood Hits	90	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

CSKI1_MOUSE
θ value	0.365318 (rank : 22)	NC score	0.032291 (rank : 38)
Query Neighborhood Hits	90	Target Neighborhood Hits	1031	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SC24B_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.037000 (rank : 32)
Query Neighborhood Hits	90	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

PO121_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.040024 (rank : 30)
Query Neighborhood Hits	90	Target Neighborhood Hits	344	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RPB1_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.047832 (rank : 25)
Query Neighborhood Hits	90	Target Neighborhood Hits	362	Shared Neighborhood Hits	15
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.047658 (rank : 26)
Query Neighborhood Hits	90	Target Neighborhood Hits	363	Shared Neighborhood Hits	15
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RTP3_MOUSE
θ value	0.62314 (rank : 27)	NC score	0.053084 (rank : 21)
Query Neighborhood Hits	90	Target Neighborhood Hits	374	Shared Neighborhood Hits	28
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

ARRB1_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.088665 (rank : 16)
Query Neighborhood Hits	90	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BWG8, Q3UH95, Q8BTJ5	Gene names	Arrb1
Domain Architecture	No domain graphic available
Description	Beta-arrestin-1 (Arrestin beta 1).

HNF3A_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.012444 (rank : 69)
Query Neighborhood Hits	90	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	P55317, Q9H2A0	Gene names	FOXA1, HNF3A, TCF3A
Domain Architecture
Description	Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1).

LDB3_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.016711 (rank : 62)
Query Neighborhood Hits	90	Target Neighborhood Hits	497	Shared Neighborhood Hits	13
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

AATK_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.005694 (rank : 88)
Query Neighborhood Hits	90	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

CIC_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.048703 (rank : 24)
Query Neighborhood Hits	90	Target Neighborhood Hits	992	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	1.06291 (rank : 33)	NC score	0.045496 (rank : 28)
Query Neighborhood Hits	90	Target Neighborhood Hits	742	Shared Neighborhood Hits	35
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LEUK_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.045837 (rank : 27)
Query Neighborhood Hits	90	Target Neighborhood Hits	147	Shared Neighborhood Hits	9
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

RREB1_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.007961 (rank : 84)
Query Neighborhood Hits	90	Target Neighborhood Hits	879	Shared Neighborhood Hits	11
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SRRM2_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.034683 (rank : 36)
Query Neighborhood Hits	90	Target Neighborhood Hits	1470	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DAB1_MOUSE
θ value	1.38821 (rank : 37)	NC score	0.029079 (rank : 45)
Query Neighborhood Hits	90	Target Neighborhood Hits	145	Shared Neighborhood Hits	8
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

MEF2D_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.034718 (rank : 35)
Query Neighborhood Hits	90	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

ATS19_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.009236 (rank : 76)
Query Neighborhood Hits	90	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

BCAR1_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.026681 (rank : 51)
Query Neighborhood Hits	90	Target Neighborhood Hits	438	Shared Neighborhood Hits	22
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

FZD1_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.009739 (rank : 75)
Query Neighborhood Hits	90	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

MUC2_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.019245 (rank : 56)
Query Neighborhood Hits	90	Target Neighborhood Hits	906	Shared Neighborhood Hits	21
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

YETS2_MOUSE
θ value	1.81305 (rank : 43)	NC score	0.032084 (rank : 40)
Query Neighborhood Hits	90	Target Neighborhood Hits	278	Shared Neighborhood Hits	19
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

BCL6_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.002547 (rank : 93)
Query Neighborhood Hits	90	Target Neighborhood Hits	922	Shared Neighborhood Hits	15
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

BRD8_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.029113 (rank : 44)
Query Neighborhood Hits	90	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

CDX1_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.006530 (rank : 86)
Query Neighborhood Hits	90	Target Neighborhood Hits	379	Shared Neighborhood Hits	8
SwissProt Accessions	P18111, Q8VCF7	Gene names	Cdx1, Cdx-1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

E2F1_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.017969 (rank : 59)
Query Neighborhood Hits	90	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

GGN_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.032119 (rank : 39)
Query Neighborhood Hits	90	Target Neighborhood Hits	311	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MAZ_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.003427 (rank : 91)
Query Neighborhood Hits	90	Target Neighborhood Hits	757	Shared Neighborhood Hits	9
SwissProt Accessions	P56270, Q15703, Q99443	Gene names	MAZ
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1) (ZF87) (ZIF87).

MEF2D_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.031615 (rank : 42)
Query Neighborhood Hits	90	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

NU155_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.025073 (rank : 54)
Query Neighborhood Hits	90	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q99P88	Gene names	Nup155
Domain Architecture
Description	Nuclear pore complex protein Nup155 (Nucleoporin Nup155) (155 kDa nucleoporin).

EPN3_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.028734 (rank : 46)
Query Neighborhood Hits	90	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

LATS2_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.001266 (rank : 94)
Query Neighborhood Hits	90	Target Neighborhood Hits	884	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

MYPC3_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.008354 (rank : 82)
Query Neighborhood Hits	90	Target Neighborhood Hits	310	Shared Neighborhood Hits	2
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

EP300_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.025721 (rank : 52)
Query Neighborhood Hits	90	Target Neighborhood Hits	821	Shared Neighborhood Hits	32
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FBLN2_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.008367 (rank : 81)
Query Neighborhood Hits	90	Target Neighborhood Hits	505	Shared Neighborhood Hits	15
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

PRGC1_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.040800 (rank : 29)
Query Neighborhood Hits	90	Target Neighborhood Hits	238	Shared Neighborhood Hits	14
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

TRPV2_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.016711 (rank : 61)
Query Neighborhood Hits	90	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

ADAM8_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.006395 (rank : 87)
Query Neighborhood Hits	90	Target Neighborhood Hits	327	Shared Neighborhood Hits	7
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

BRD8_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.030954 (rank : 43)
Query Neighborhood Hits	90	Target Neighborhood Hits	422	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CO039_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.027620 (rank : 49)
Query Neighborhood Hits	90	Target Neighborhood Hits	445	Shared Neighborhood Hits	25
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CT174_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.028318 (rank : 47)
Query Neighborhood Hits	90	Target Neighborhood Hits	181	Shared Neighborhood Hits	9
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

HEY2_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.013380 (rank : 66)
Query Neighborhood Hits	90	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

IF35_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.018839 (rank : 57)
Query Neighborhood Hits	90	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

LMO6_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.010339 (rank : 73)
Query Neighborhood Hits	90	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VL3, Q8CAY9	Gene names	Lmo6
Domain Architecture	No domain graphic available
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

MAZ_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.002652 (rank : 92)
Query Neighborhood Hits	90	Target Neighborhood Hits	745	Shared Neighborhood Hits	8
SwissProt Accessions	P56671, Q9R1W0	Gene names	Maz
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1).

MINT_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.018715 (rank : 58)
Query Neighborhood Hits	90	Target Neighborhood Hits	1514	Shared Neighborhood Hits	41
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PRGC1_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.038965 (rank : 31)
Query Neighborhood Hits	90	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

RERE_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.027633 (rank : 48)
Query Neighborhood Hits	90	Target Neighborhood Hits	785	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ATX2L_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.022116 (rank : 55)
Query Neighborhood Hits	90	Target Neighborhood Hits	443	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CBP_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.025552 (rank : 53)
Query Neighborhood Hits	90	Target Neighborhood Hits	941	Shared Neighborhood Hits	32
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PDC6I_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.013282 (rank : 67)
Query Neighborhood Hits	90	Target Neighborhood Hits	278	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PO2F1_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.008375 (rank : 80)
Query Neighborhood Hits	90	Target Neighborhood Hits	426	Shared Neighborhood Hits	8
SwissProt Accessions	P14859, Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1	Gene names	POU2F1, OCT1, OTF1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

PROX1_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.013729 (rank : 64)
Query Neighborhood Hits	90	Target Neighborhood Hits	184	Shared Neighborhood Hits	2
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

RD23B_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.013459 (rank : 65)
Query Neighborhood Hits	90	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

SYP2L_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.014480 (rank : 63)
Query Neighborhood Hits	90	Target Neighborhood Hits	400	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TF7L1_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.013016 (rank : 68)
Query Neighborhood Hits	90	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TTC3_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.007941 (rank : 85)
Query Neighborhood Hits	90	Target Neighborhood Hits	664	Shared Neighborhood Hits	2
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

WASIP_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.027216 (rank : 50)
Query Neighborhood Hits	90	Target Neighborhood Hits	458	Shared Neighborhood Hits	20
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ABI3_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.008112 (rank : 83)
Query Neighborhood Hits	90	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CEL_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.017870 (rank : 60)
Query Neighborhood Hits	90	Target Neighborhood Hits	896	Shared Neighborhood Hits	34
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

MGR5_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.004288 (rank : 89)
Query Neighborhood Hits	90	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

NOTC1_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.003428 (rank : 90)
Query Neighborhood Hits	90	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PHAR2_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.011633 (rank : 71)
Query Neighborhood Hits	90	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

PO2F1_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.008682 (rank : 78)
Query Neighborhood Hits	90	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

PO6F2_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.009935 (rank : 74)
Query Neighborhood Hits	90	Target Neighborhood Hits	618	Shared Neighborhood Hits	18
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PUM2_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.008656 (rank : 79)
Query Neighborhood Hits	90	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

SFPQ_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.010984 (rank : 72)
Query Neighborhood Hits	90	Target Neighborhood Hits	958	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SIAH2_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.008912 (rank : 77)
Query Neighborhood Hits	90	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SP110_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.012350 (rank : 70)
Query Neighborhood Hits	90	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

ARRC_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.051159 (rank : 22)
Query Neighborhood Hits	90	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P36575, Q5JT23, Q5JT24, Q6IBF5, Q96EN2	Gene names	ARR3, ARRX, CAR
Domain Architecture
Description	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3) (X- arrestin) (C-arrestin).

ARRC_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.074899 (rank : 17)
Query Neighborhood Hits	90	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQP6	Gene names	Arr3
Domain Architecture
Description	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3).

ARRS_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.051000 (rank : 23)
Query Neighborhood Hits	90	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	P10523, Q53SV3, Q99858	Gene names	SAG
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

ARRS_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.053764 (rank : 20)
Query Neighborhood Hits	90	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P20443, Q91W62	Gene names	Sag
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

Hits sorted by NC score

ARRD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	90
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ARRD1_HUMAN
NC score	0.973047 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	90	Target Neighborhood Hits	75	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ARRD2_MOUSE
NC score	0.752109 (rank : 3)	θ value	2.35151e-24 (rank : 3)
Query Neighborhood Hits	90	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D668, Q3UVK8, Q3UXC6	Gene names	Arrdc2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ARRD2_HUMAN
NC score	0.743817 (rank : 4)	θ value	8.93572e-24 (rank : 4)
Query Neighborhood Hits	90	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TBH0, O95895, Q6ZRV9, Q8WYG6	Gene names	ARRDC2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ARRD4_HUMAN
NC score	0.734026 (rank : 5)	θ value	1.2077e-20 (rank : 5)
Query Neighborhood Hits	90	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NCT1, Q6NSI9	Gene names	ARRDC4
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 4.

ARRD3_MOUSE
NC score	0.721970 (rank : 6)	θ value	2.27762e-19 (rank : 7)
Query Neighborhood Hits	90	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TPQ9, Q4KMN0, Q80TE6, Q8K0L7	Gene names	Arrdc3, Kiaa1376
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 3.

ARRD3_HUMAN
NC score	0.719368 (rank : 7)	θ value	2.27762e-19 (rank : 6)
Query Neighborhood Hits	90	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q96B67, Q9P2H1	Gene names	ARRDC3, KIAA1376
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 3.

TXNIP_HUMAN
NC score	0.698244 (rank : 8)	θ value	4.74913e-17 (rank : 8)
Query Neighborhood Hits	90	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3M7, Q16226, Q6PML0, Q9BXG9	Gene names	TXNIP, VDUP1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1) (Thioredoxin-binding protein 2).

TXNIP_MOUSE
NC score	0.695192 (rank : 9)	θ value	1.80466e-16 (rank : 9)
Query Neighborhood Hits	90	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BG60, Q8BGQ0, Q8K2B2, Q9DC00, Q9EP90, Q9R115	Gene names	Txnip, Vdup1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1).

ARRD5_MOUSE
NC score	0.516707 (rank : 10)	θ value	7.59969e-07 (rank : 10)
Query Neighborhood Hits	90	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q497K5	Gene names	Arrdc5
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 5.

DSCR3_MOUSE
NC score	0.146164 (rank : 11)	θ value	0.0431538 (rank : 14)
Query Neighborhood Hits	90	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O35075, Q542V5	Gene names	Dscr3, Dcra, Dscra
Domain Architecture
Description	Down syndrome critical region protein 3 homolog (Down syndrome critical region protein A homolog).

DSCR3_HUMAN
NC score	0.143639 (rank : 12)	θ value	0.0330416 (rank : 12)
Query Neighborhood Hits	90	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O14972	Gene names	DSCR3, DCRA, DSCRA
Domain Architecture
Description	Down syndrome critical region protein 3 (Down syndrome critical region protein A).

ARRB2_HUMAN
NC score	0.104272 (rank : 13)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	90	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	P32121, Q0Z8D3, Q2PP19, Q6ICT3, Q8N7Y2, Q9UEQ6	Gene names	ARRB2, ARB2, ARR2
Domain Architecture
Description	Beta-arrestin-2 (Arrestin beta 2).

ARRB1_HUMAN
NC score	0.102933 (rank : 14)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	90	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P49407, O75625, O75630, Q2PP20, Q9BTK8	Gene names	ARRB1, ARR1
Domain Architecture
Description	Beta-arrestin-1 (Arrestin beta 1).

ARRB2_MOUSE
NC score	0.094586 (rank : 15)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	90	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YI4, Q3TCM2, Q5F2D8, Q5F2E0	Gene names	Arrb2
Domain Architecture
Description	Beta-arrestin-2 (Arrestin beta 2).

ARRB1_MOUSE
NC score	0.088665 (rank : 16)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	90	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BWG8, Q3UH95, Q8BTJ5	Gene names	Arrb1
Domain Architecture	No domain graphic available
Description	Beta-arrestin-1 (Arrestin beta 1).

ARRC_MOUSE
NC score	0.074899 (rank : 17)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	90	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQP6	Gene names	Arr3
Domain Architecture
Description	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3).

MLL2_HUMAN
NC score	0.055026 (rank : 18)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	90	Target Neighborhood Hits	1788	Shared Neighborhood Hits	40
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ATN1_HUMAN
NC score	0.054237 (rank : 19)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	90	Target Neighborhood Hits	676	Shared Neighborhood Hits	24
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ARRS_MOUSE
NC score	0.053764 (rank : 20)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	90	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P20443, Q91W62	Gene names	Sag
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

RTP3_MOUSE
NC score	0.053084 (rank : 21)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	90	Target Neighborhood Hits	374	Shared Neighborhood Hits	28
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

ARRC_HUMAN
NC score	0.051159 (rank : 22)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	90	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P36575, Q5JT23, Q5JT24, Q6IBF5, Q96EN2	Gene names	ARR3, ARRX, CAR
Domain Architecture
Description	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3) (X- arrestin) (C-arrestin).

ARRS_HUMAN
NC score	0.051000 (rank : 23)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	90	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	P10523, Q53SV3, Q99858	Gene names	SAG
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

CIC_HUMAN
NC score	0.048703 (rank : 24)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	90	Target Neighborhood Hits	992	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RPB1_HUMAN
NC score	0.047832 (rank : 25)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	90	Target Neighborhood Hits	362	Shared Neighborhood Hits	15
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
NC score	0.047658 (rank : 26)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	90	Target Neighborhood Hits	363	Shared Neighborhood Hits	15
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

LEUK_MOUSE
NC score	0.045837 (rank : 27)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	90	Target Neighborhood Hits	147	Shared Neighborhood Hits	9
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

CIC_MOUSE
NC score	0.045496 (rank : 28)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	90	Target Neighborhood Hits	742	Shared Neighborhood Hits	35
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

PRGC1_MOUSE
NC score	0.040800 (rank : 29)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	90	Target Neighborhood Hits	238	Shared Neighborhood Hits	14
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

PO121_HUMAN
NC score	0.040024 (rank : 30)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	90	Target Neighborhood Hits	344	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PRGC1_HUMAN
NC score	0.038965 (rank : 31)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	90	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

SC24B_HUMAN
NC score	0.037000 (rank : 32)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	90	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

K1802_HUMAN
NC score	0.035832 (rank : 33)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	90	Target Neighborhood Hits	1378	Shared Neighborhood Hits	40
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TBR1_MOUSE
NC score	0.034899 (rank : 34)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	90	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

MEF2D_MOUSE
NC score	0.034718 (rank : 35)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	90	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

SRRM2_MOUSE
NC score	0.034683 (rank : 36)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	90	Target Neighborhood Hits	1470	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TBR1_HUMAN
NC score	0.033948 (rank : 37)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	90	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

CSKI1_MOUSE
NC score	0.032291 (rank : 38)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	90	Target Neighborhood Hits	1031	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GGN_MOUSE
NC score	0.032119 (rank : 39)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	90	Target Neighborhood Hits	311	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

YETS2_MOUSE
NC score	0.032084 (rank : 40)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	90	Target Neighborhood Hits	278	Shared Neighborhood Hits	19
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

CSKI1_HUMAN
NC score	0.032053 (rank : 41)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	90	Target Neighborhood Hits	997	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MEF2D_HUMAN
NC score	0.031615 (rank : 42)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	90	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

BRD8_MOUSE
NC score	0.030954 (rank : 43)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	90	Target Neighborhood Hits	422	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRD8_HUMAN
NC score	0.029113 (rank : 44)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	90	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

DAB1_MOUSE
NC score	0.029079 (rank : 45)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	90	Target Neighborhood Hits	145	Shared Neighborhood Hits	8
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

EPN3_HUMAN
NC score	0.028734 (rank : 46)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	90	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

CT174_HUMAN
NC score	0.028318 (rank : 47)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	90	Target Neighborhood Hits	181	Shared Neighborhood Hits	9
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

RERE_MOUSE
NC score	0.027633 (rank : 48)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	90	Target Neighborhood Hits	785	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CO039_MOUSE
NC score	0.027620 (rank : 49)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	90	Target Neighborhood Hits	445	Shared Neighborhood Hits	25
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

WASIP_HUMAN
NC score	0.027216 (rank : 50)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	90	Target Neighborhood Hits	458	Shared Neighborhood Hits	20
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BCAR1_MOUSE
NC score	0.026681 (rank : 51)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	90	Target Neighborhood Hits	438	Shared Neighborhood Hits	22
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

EP300_HUMAN
NC score	0.025721 (rank : 52)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	90	Target Neighborhood Hits	821	Shared Neighborhood Hits	32
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CBP_HUMAN
NC score	0.025552 (rank : 53)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	90	Target Neighborhood Hits	941	Shared Neighborhood Hits	32
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NU155_MOUSE
NC score	0.025073 (rank : 54)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	90	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q99P88	Gene names	Nup155
Domain Architecture
Description	Nuclear pore complex protein Nup155 (Nucleoporin Nup155) (155 kDa nucleoporin).

ATX2L_HUMAN
NC score	0.022116 (rank : 55)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	90	Target Neighborhood Hits	443	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

MUC2_HUMAN
NC score	0.019245 (rank : 56)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	90	Target Neighborhood Hits	906	Shared Neighborhood Hits	21
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

IF35_MOUSE
NC score	0.018839 (rank : 57)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	90	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

MINT_MOUSE
NC score	0.018715 (rank : 58)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	90	Target Neighborhood Hits	1514	Shared Neighborhood Hits	41
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

E2F1_HUMAN
NC score	0.017969 (rank : 59)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	90	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

CEL_HUMAN
NC score	0.017870 (rank : 60)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	90	Target Neighborhood Hits	896	Shared Neighborhood Hits	34
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

TRPV2_MOUSE
NC score	0.016711 (rank : 61)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	90	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

LDB3_HUMAN
NC score	0.016711 (rank : 62)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	90	Target Neighborhood Hits	497	Shared Neighborhood Hits	13
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

SYP2L_HUMAN
NC score	0.014480 (rank : 63)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	90	Target Neighborhood Hits	400	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PROX1_MOUSE
NC score	0.013729 (rank : 64)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	90	Target Neighborhood Hits	184	Shared Neighborhood Hits	2
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

RD23B_HUMAN
NC score	0.013459 (rank : 65)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	90	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

HEY2_HUMAN
NC score	0.013380 (rank : 66)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	90	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

PDC6I_HUMAN
NC score	0.013282 (rank : 67)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	90	Target Neighborhood Hits	278	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

TF7L1_HUMAN
NC score	0.013016 (rank : 68)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	90	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

HNF3A_HUMAN
NC score	0.012444 (rank : 69)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	90	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	P55317, Q9H2A0	Gene names	FOXA1, HNF3A, TCF3A
Domain Architecture
Description	Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1).

SP110_HUMAN
NC score	0.012350 (rank : 70)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	90	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

PHAR2_HUMAN
NC score	0.011633 (rank : 71)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	90	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

SFPQ_MOUSE
NC score	0.010984 (rank : 72)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	90	Target Neighborhood Hits	958	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

LMO6_MOUSE
NC score	0.010339 (rank : 73)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	90	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VL3, Q8CAY9	Gene names	Lmo6
Domain Architecture	No domain graphic available
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

PO6F2_HUMAN
NC score	0.009935 (rank : 74)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	90	Target Neighborhood Hits	618	Shared Neighborhood Hits	18
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

FZD1_HUMAN
NC score	0.009739 (rank : 75)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	90	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

ATS19_MOUSE
NC score	0.009236 (rank : 76)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	90	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

SIAH2_MOUSE
NC score	0.008912 (rank : 77)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	90	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

PO2F1_MOUSE
NC score	0.008682 (rank : 78)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	90	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

PUM2_MOUSE
NC score	0.008656 (rank : 79)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	90	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

PO2F1_HUMAN
NC score	0.008375 (rank : 80)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	90	Target Neighborhood Hits	426	Shared Neighborhood Hits	8
SwissProt Accessions	P14859, Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1	Gene names	POU2F1, OCT1, OTF1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

FBLN2_MOUSE
NC score	0.008367 (rank : 81)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	90	Target Neighborhood Hits	505	Shared Neighborhood Hits	15
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

MYPC3_MOUSE
NC score	0.008354 (rank : 82)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	90	Target Neighborhood Hits	310	Shared Neighborhood Hits	2
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

ABI3_HUMAN
NC score	0.008112 (rank : 83)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	90	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

RREB1_HUMAN
NC score	0.007961 (rank : 84)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	90	Target Neighborhood Hits	879	Shared Neighborhood Hits	11
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

TTC3_HUMAN
NC score	0.007941 (rank : 85)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	90	Target Neighborhood Hits	664	Shared Neighborhood Hits	2
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

CDX1_MOUSE
NC score	0.006530 (rank : 86)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	90	Target Neighborhood Hits	379	Shared Neighborhood Hits	8
SwissProt Accessions	P18111, Q8VCF7	Gene names	Cdx1, Cdx-1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

ADAM8_HUMAN
NC score	0.006395 (rank : 87)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	90	Target Neighborhood Hits	327	Shared Neighborhood Hits	7
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

AATK_MOUSE
NC score	0.005694 (rank : 88)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	90	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

MGR5_HUMAN
NC score	0.004288 (rank : 89)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	90	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

NOTC1_HUMAN
NC score	0.003428 (rank : 90)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	90	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MAZ_HUMAN
NC score	0.003427 (rank : 91)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	90	Target Neighborhood Hits	757	Shared Neighborhood Hits	9
SwissProt Accessions	P56270, Q15703, Q99443	Gene names	MAZ
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1) (ZF87) (ZIF87).

MAZ_MOUSE
NC score	0.002652 (rank : 92)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	90	Target Neighborhood Hits	745	Shared Neighborhood Hits	8
SwissProt Accessions	P56671, Q9R1W0	Gene names	Maz
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1).

BCL6_HUMAN
NC score	0.002547 (rank : 93)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	90	Target Neighborhood Hits	922	Shared Neighborhood Hits	15
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

LATS2_HUMAN
NC score	0.001266 (rank : 94)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	90	Target Neighborhood Hits	884	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).