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Network neighborhood for query Sequence : AXN2_MOUSE

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AXN2_MOUSE
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AXN2_HUMAN
θ value	0 (rank : 1)	NC score	0.989516 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	102	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN1_MOUSE
θ value	3.7435e-147 (rank : 3)	NC score	0.948949 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	89	Shared Neighborhood Hits	49
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AXN1_HUMAN
θ value	2.77624e-142 (rank : 4)	NC score	0.948670 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

RGS18_HUMAN
θ value	1.68911e-14 (rank : 5)	NC score	0.677020 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS18_MOUSE
θ value	1.09485e-13 (rank : 6)	NC score	0.675483 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS3_HUMAN
θ value	4.16044e-13 (rank : 7)	NC score	0.489779 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	1375	Shared Neighborhood Hits	76
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	1.02475e-11 (rank : 8)	NC score	0.432395 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	1621	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RGS2_HUMAN
θ value	2.98157e-11 (rank : 9)	NC score	0.660500 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS10_HUMAN
θ value	5.08577e-11 (rank : 10)	NC score	0.679279 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS1_HUMAN
θ value	1.133e-10 (rank : 11)	NC score	0.660094 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS2_MOUSE
θ value	1.133e-10 (rank : 12)	NC score	0.656380 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	52	Shared Neighborhood Hits	42
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS1_MOUSE
θ value	1.47974e-10 (rank : 13)	NC score	0.656473 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS8_MOUSE
θ value	1.47974e-10 (rank : 14)	NC score	0.657859 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS8_HUMAN
θ value	1.9326e-10 (rank : 15)	NC score	0.657068 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS10_MOUSE
θ value	4.30538e-10 (rank : 16)	NC score	0.671350 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS5_HUMAN
θ value	4.30538e-10 (rank : 17)	NC score	0.659034 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	52	Shared Neighborhood Hits	42
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS4_HUMAN
θ value	5.62301e-10 (rank : 18)	NC score	0.652517 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS4_MOUSE
θ value	2.79066e-09 (rank : 19)	NC score	0.651500 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS5_MOUSE
θ value	2.79066e-09 (rank : 20)	NC score	0.652500 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS13_HUMAN
θ value	1.06045e-08 (rank : 21)	NC score	0.645154 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS14_MOUSE
θ value	1.80886e-08 (rank : 22)	NC score	0.606304 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS16_HUMAN
θ value	2.36244e-08 (rank : 23)	NC score	0.640992 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS19_MOUSE
θ value	4.0297e-08 (rank : 24)	NC score	0.622748 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS16_MOUSE
θ value	6.87365e-08 (rank : 25)	NC score	0.643552 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS13_MOUSE
θ value	8.97725e-08 (rank : 26)	NC score	0.645921 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS14_HUMAN
θ value	1.53129e-07 (rank : 27)	NC score	0.596286 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS19_HUMAN
θ value	1.99992e-07 (rank : 28)	NC score	0.620785 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS20_MOUSE
θ value	4.45536e-07 (rank : 29)	NC score	0.620762 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS17_MOUSE
θ value	1.29631e-06 (rank : 30)	NC score	0.623291 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS11_HUMAN
θ value	2.88788e-06 (rank : 31)	NC score	0.551682 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS17_HUMAN
θ value	2.88788e-06 (rank : 32)	NC score	0.614581 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS20_HUMAN
θ value	4.92598e-06 (rank : 33)	NC score	0.608154 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

DVL2_HUMAN
θ value	6.43352e-06 (rank : 34)	NC score	0.246146 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	6.43352e-06 (rank : 35)	NC score	0.246155 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	233	Shared Neighborhood Hits	22
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	6.43352e-06 (rank : 36)	NC score	0.253483 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	6.43352e-06 (rank : 37)	NC score	0.253796 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

RGS9_HUMAN
θ value	2.44474e-05 (rank : 38)	NC score	0.530641 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_MOUSE
θ value	2.44474e-05 (rank : 39)	NC score	0.531204 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	65	Shared Neighborhood Hits	47
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS12_HUMAN
θ value	5.44631e-05 (rank : 40)	NC score	0.502127 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	333	Shared Neighborhood Hits	59
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

DVL1L_HUMAN
θ value	0.00020696 (rank : 41)	NC score	0.229242 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	146	Shared Neighborhood Hits	15
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_MOUSE
θ value	0.00020696 (rank : 42)	NC score	0.226719 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	146	Shared Neighborhood Hits	15
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_HUMAN
θ value	0.000270298 (rank : 43)	NC score	0.226299 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	158	Shared Neighborhood Hits	16
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

RGS6_MOUSE
θ value	0.000270298 (rank : 44)	NC score	0.487156 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS7_HUMAN
θ value	0.00035302 (rank : 45)	NC score	0.500667 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	82	Shared Neighborhood Hits	44
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

PO6F2_MOUSE
θ value	0.000786445 (rank : 46)	NC score	0.048084 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	639	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RGS7_MOUSE
θ value	0.000786445 (rank : 47)	NC score	0.493758 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS6_HUMAN
θ value	0.00509761 (rank : 48)	NC score	0.459423 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	80	Shared Neighborhood Hits	40
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

MSH3_HUMAN
θ value	0.0961366 (rank : 49)	NC score	0.029051 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

AHTF1_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.049266 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

K0310_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.063321 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	420	Shared Neighborhood Hits	19
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

JIP3_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.025811 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	1039	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CT112_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.041901 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

NDF2_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.015440 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

SCG2_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.039717 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

VAPB_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.025194 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

IWS1_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.020684 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	1258	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

COBA2_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.022522 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CV106_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.040360 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

CXA1_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.011485 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P17302, Q9Y5I8	Gene names	GJA1, GJAL
Domain Architecture
Description	Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein).

GP156_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.022397 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

PCLO_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.019387 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	2046	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ABLM1_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.006009 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	356	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

AKA10_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.193397 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.192497 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

CO8A2_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.023555 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	299	Shared Neighborhood Hits	21
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CT112_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.030996 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

FURIN_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.010176 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

K0562_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.020337 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	146	Shared Neighborhood Hits	2
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

K1949_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.035385 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

NFH_MOUSE
θ value	1.81305 (rank : 71)	NC score	0.012634 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	2247	Shared Neighborhood Hits	34
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TNC6B_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.026081 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	256	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

IASPP_MOUSE
θ value	2.36792 (rank : 73)	NC score	0.015847 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	1024	Shared Neighborhood Hits	26
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ULK2_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.000849 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	979	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

ARHGG_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.009874 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CO1A2_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.020688 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	329	Shared Neighborhood Hits	20
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A5_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.028189 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	383	Shared Neighborhood Hits	23
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

OBSCN_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.000399 (rank : 117)
Query Neighborhood Hits	116	Target Neighborhood Hits	1931	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PUNC_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.006032 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	449	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

CO4A3_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.022105 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	421	Shared Neighborhood Hits	24
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO9A2_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.023476 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	279	Shared Neighborhood Hits	21
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

ERBB3_MOUSE
θ value	4.03905 (rank : 82)	NC score	-0.000263 (rank : 118)
Query Neighborhood Hits	116	Target Neighborhood Hits	898	Shared Neighborhood Hits	6
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

SET1A_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.026742 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	690	Shared Neighborhood Hits	12
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TCEA2_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.010498 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q15560, Q8TD37, Q8TD38	Gene names	TCEA2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Transcription elongation factor TFIIS.l).

ANGL3_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.004330 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

CO4A4_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.021775 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	440	Shared Neighborhood Hits	21
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CXA1_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.009038 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P23242	Gene names	Gja1, Cxn-43
Domain Architecture
Description	Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein).

HS90A_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.011809 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.011328 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

IQEC3_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.012419 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

RNF39_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.005204 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

ZN692_HUMAN
θ value	5.27518 (rank : 92)	NC score	-0.001519 (rank : 121)
Query Neighborhood Hits	116	Target Neighborhood Hits	808	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

CCD16_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.010453 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

CO4A1_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.020366 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO9A1_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.018583 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	477	Shared Neighborhood Hits	23
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ERBB3_HUMAN
θ value	6.88961 (rank : 96)	NC score	-0.000707 (rank : 119)
Query Neighborhood Hits	116	Target Neighborhood Hits	918	Shared Neighborhood Hits	6
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

HXB3_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.005406 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	493	Shared Neighborhood Hits	15
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

HXD3_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.006893 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	433	Shared Neighborhood Hits	10
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

IASPP_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.013663 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	688	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ITPR3_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.008385 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

SAM68_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.011022 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SCG2_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.024599 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

ZN516_MOUSE
θ value	6.88961 (rank : 103)	NC score	-0.001197 (rank : 120)
Query Neighborhood Hits	116	Target Neighborhood Hits	1197	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CO4A1_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.021198 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	450	Shared Neighborhood Hits	23
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO9A1_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.017831 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	420	Shared Neighborhood Hits	22
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

HXB3_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.005413 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	559	Shared Neighborhood Hits	13
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

HXD3_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.004418 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	435	Shared Neighborhood Hits	7
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

IQEC3_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.015300 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

KIF1A_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.004908 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	239	Shared Neighborhood Hits	3
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

NFH_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.013467 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	1242	Shared Neighborhood Hits	15
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SHAN1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.009207 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	1041	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

T22D2_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.024743 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TRRAP_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.016281 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

TRRAP_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.014914 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

UBP42_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.012896 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	445	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

US6NL_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.006516 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

SNX13_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.157868 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX13_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.160708 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNX14_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.073765 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.072766 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX25_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.071898 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

Hits sorted by NC score

AXN2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN2_HUMAN
NC score	0.989516 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	102	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN1_MOUSE
NC score	0.948949 (rank : 3)	θ value	3.7435e-147 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	89	Shared Neighborhood Hits	49
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AXN1_HUMAN
NC score	0.948670 (rank : 4)	θ value	2.77624e-142 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

RGS10_HUMAN
NC score	0.679279 (rank : 5)	θ value	5.08577e-11 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS18_HUMAN
NC score	0.677020 (rank : 6)	θ value	1.68911e-14 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS18_MOUSE
NC score	0.675483 (rank : 7)	θ value	1.09485e-13 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS10_MOUSE
NC score	0.671350 (rank : 8)	θ value	4.30538e-10 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS2_HUMAN
NC score	0.660500 (rank : 9)	θ value	2.98157e-11 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS1_HUMAN
NC score	0.660094 (rank : 10)	θ value	1.133e-10 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS5_HUMAN
NC score	0.659034 (rank : 11)	θ value	4.30538e-10 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	52	Shared Neighborhood Hits	42
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS8_MOUSE
NC score	0.657859 (rank : 12)	θ value	1.47974e-10 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS8_HUMAN
NC score	0.657068 (rank : 13)	θ value	1.9326e-10 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS1_MOUSE
NC score	0.656473 (rank : 14)	θ value	1.47974e-10 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS2_MOUSE
NC score	0.656380 (rank : 15)	θ value	1.133e-10 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	52	Shared Neighborhood Hits	42
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS4_HUMAN
NC score	0.652517 (rank : 16)	θ value	5.62301e-10 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS5_MOUSE
NC score	0.652500 (rank : 17)	θ value	2.79066e-09 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS4_MOUSE
NC score	0.651500 (rank : 18)	θ value	2.79066e-09 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS13_MOUSE
NC score	0.645921 (rank : 19)	θ value	8.97725e-08 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS13_HUMAN
NC score	0.645154 (rank : 20)	θ value	1.06045e-08 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS16_MOUSE
NC score	0.643552 (rank : 21)	θ value	6.87365e-08 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS16_HUMAN
NC score	0.640992 (rank : 22)	θ value	2.36244e-08 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS17_MOUSE
NC score	0.623291 (rank : 23)	θ value	1.29631e-06 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS19_MOUSE
NC score	0.622748 (rank : 24)	θ value	4.0297e-08 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS19_HUMAN
NC score	0.620785 (rank : 25)	θ value	1.99992e-07 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS20_MOUSE
NC score	0.620762 (rank : 26)	θ value	4.45536e-07 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS17_HUMAN
NC score	0.614581 (rank : 27)	θ value	2.88788e-06 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS20_HUMAN
NC score	0.608154 (rank : 28)	θ value	4.92598e-06 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS14_MOUSE
NC score	0.606304 (rank : 29)	θ value	1.80886e-08 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS14_HUMAN
NC score	0.596286 (rank : 30)	θ value	1.53129e-07 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS11_HUMAN
NC score	0.551682 (rank : 31)	θ value	2.88788e-06 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS9_MOUSE
NC score	0.531204 (rank : 32)	θ value	2.44474e-05 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	65	Shared Neighborhood Hits	47
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_HUMAN
NC score	0.530641 (rank : 33)	θ value	2.44474e-05 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS12_HUMAN
NC score	0.502127 (rank : 34)	θ value	5.44631e-05 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	333	Shared Neighborhood Hits	59
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS7_HUMAN
NC score	0.500667 (rank : 35)	θ value	0.00035302 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	82	Shared Neighborhood Hits	44
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_MOUSE
NC score	0.493758 (rank : 36)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS3_HUMAN
NC score	0.489779 (rank : 37)	θ value	4.16044e-13 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	1375	Shared Neighborhood Hits	76
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS6_MOUSE
NC score	0.487156 (rank : 38)	θ value	0.000270298 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS6_HUMAN
NC score	0.459423 (rank : 39)	θ value	0.00509761 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	80	Shared Neighborhood Hits	40
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

RGS3_MOUSE
NC score	0.432395 (rank : 40)	θ value	1.02475e-11 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	1621	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DVL3_MOUSE
NC score	0.253796 (rank : 41)	θ value	6.43352e-06 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_HUMAN
NC score	0.253483 (rank : 42)	θ value	6.43352e-06 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL2_MOUSE
NC score	0.246155 (rank : 43)	θ value	6.43352e-06 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	233	Shared Neighborhood Hits	22
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_HUMAN
NC score	0.246146 (rank : 44)	θ value	6.43352e-06 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL1L_HUMAN
NC score	0.229242 (rank : 45)	θ value	0.00020696 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	146	Shared Neighborhood Hits	15
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_MOUSE
NC score	0.226719 (rank : 46)	θ value	0.00020696 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	146	Shared Neighborhood Hits	15
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_HUMAN
NC score	0.226299 (rank : 47)	θ value	0.000270298 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	158	Shared Neighborhood Hits	16
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

AKA10_HUMAN
NC score	0.193397 (rank : 48)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
NC score	0.192497 (rank : 49)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SNX13_MOUSE
NC score	0.160708 (rank : 50)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	116	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNX13_HUMAN
NC score	0.157868 (rank : 51)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX14_HUMAN
NC score	0.073765 (rank : 52)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
NC score	0.072766 (rank : 53)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	116	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX25_HUMAN
NC score	0.071898 (rank : 54)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

K0310_HUMAN
NC score	0.063321 (rank : 55)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	420	Shared Neighborhood Hits	19
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

AHTF1_HUMAN
NC score	0.049266 (rank : 56)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

PO6F2_MOUSE
NC score	0.048084 (rank : 57)	θ value	0.000786445 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	639	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

CT112_HUMAN
NC score	0.041901 (rank : 58)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

CV106_HUMAN
NC score	0.040360 (rank : 59)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

SCG2_HUMAN
NC score	0.039717 (rank : 60)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

K1949_HUMAN
NC score	0.035385 (rank : 61)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

CT112_MOUSE
NC score	0.030996 (rank : 62)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

MSH3_HUMAN
NC score	0.029051 (rank : 63)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

CO4A5_HUMAN
NC score	0.028189 (rank : 64)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	383	Shared Neighborhood Hits	23
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

SET1A_HUMAN
NC score	0.026742 (rank : 65)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	690	Shared Neighborhood Hits	12
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TNC6B_HUMAN
NC score	0.026081 (rank : 66)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	256	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

JIP3_HUMAN
NC score	0.025811 (rank : 67)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	1039	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

VAPB_MOUSE
NC score	0.025194 (rank : 68)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

T22D2_HUMAN
NC score	0.024743 (rank : 69)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

SCG2_MOUSE
NC score	0.024599 (rank : 70)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

CO8A2_HUMAN
NC score	0.023555 (rank : 71)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	299	Shared Neighborhood Hits	21
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CO9A2_MOUSE
NC score	0.023476 (rank : 72)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	279	Shared Neighborhood Hits	21
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COBA2_HUMAN
NC score	0.022522 (rank : 73)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

GP156_HUMAN
NC score	0.022397 (rank : 74)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

CO4A3_HUMAN
NC score	0.022105 (rank : 75)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	421	Shared Neighborhood Hits	24
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO4A4_HUMAN
NC score	0.021775 (rank : 76)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	440	Shared Neighborhood Hits	21
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO4A1_MOUSE
NC score	0.021198 (rank : 77)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	450	Shared Neighborhood Hits	23
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO1A2_HUMAN
NC score	0.020688 (rank : 78)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	329	Shared Neighborhood Hits	20
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

IWS1_MOUSE
NC score	0.020684 (rank : 79)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	1258	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CO4A1_HUMAN
NC score	0.020366 (rank : 80)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

K0562_HUMAN
NC score	0.020337 (rank : 81)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	146	Shared Neighborhood Hits	2
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

PCLO_HUMAN
NC score	0.019387 (rank : 82)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	2046	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CO9A1_MOUSE
NC score	0.018583 (rank : 83)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	477	Shared Neighborhood Hits	23
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A1_HUMAN
NC score	0.017831 (rank : 84)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	420	Shared Neighborhood Hits	22
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

TRRAP_HUMAN
NC score	0.016281 (rank : 85)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

IASPP_MOUSE
NC score	0.015847 (rank : 86)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	1024	Shared Neighborhood Hits	26
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NDF2_HUMAN
NC score	0.015440 (rank : 87)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

IQEC3_MOUSE
NC score	0.015300 (rank : 88)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

TRRAP_MOUSE
NC score	0.014914 (rank : 89)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

IASPP_HUMAN
NC score	0.013663 (rank : 90)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	688	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NFH_HUMAN
NC score	0.013467 (rank : 91)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	1242	Shared Neighborhood Hits	15
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

UBP42_HUMAN
NC score	0.012896 (rank : 92)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	445	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

NFH_MOUSE
NC score	0.012634 (rank : 93)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	2247	Shared Neighborhood Hits	34
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

IQEC3_HUMAN
NC score	0.012419 (rank : 94)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

HS90A_HUMAN
NC score	0.011809 (rank : 95)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

CXA1_HUMAN
NC score	0.011485 (rank : 96)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P17302, Q9Y5I8	Gene names	GJA1, GJAL
Domain Architecture
Description	Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein).

HS90A_MOUSE
NC score	0.011328 (rank : 97)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

SAM68_HUMAN
NC score	0.011022 (rank : 98)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

TCEA2_HUMAN
NC score	0.010498 (rank : 99)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q15560, Q8TD37, Q8TD38	Gene names	TCEA2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Transcription elongation factor TFIIS.l).

CCD16_MOUSE
NC score	0.010453 (rank : 100)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

FURIN_MOUSE
NC score	0.010176 (rank : 101)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

ARHGG_HUMAN
NC score	0.009874 (rank : 102)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

SHAN1_HUMAN
NC score	0.009207 (rank : 103)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	1041	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

CXA1_MOUSE
NC score	0.009038 (rank : 104)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P23242	Gene names	Gja1, Cxn-43
Domain Architecture
Description	Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein).

ITPR3_MOUSE
NC score	0.008385 (rank : 105)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

HXD3_HUMAN
NC score	0.006893 (rank : 106)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	433	Shared Neighborhood Hits	10
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

US6NL_MOUSE
NC score	0.006516 (rank : 107)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

PUNC_HUMAN
NC score	0.006032 (rank : 108)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	449	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ABLM1_MOUSE
NC score	0.006009 (rank : 109)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	356	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

HXB3_HUMAN
NC score	0.005413 (rank : 110)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	559	Shared Neighborhood Hits	13
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

HXB3_MOUSE
NC score	0.005406 (rank : 111)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	493	Shared Neighborhood Hits	15
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

RNF39_HUMAN
NC score	0.005204 (rank : 112)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

KIF1A_MOUSE
NC score	0.004908 (rank : 113)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	239	Shared Neighborhood Hits	3
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

HXD3_MOUSE
NC score	0.004418 (rank : 114)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	435	Shared Neighborhood Hits	7
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

ANGL3_MOUSE
NC score	0.004330 (rank : 115)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ULK2_HUMAN
NC score	0.000849 (rank : 116)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	979	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

OBSCN_HUMAN
NC score	0.000399 (rank : 117)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	1931	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ERBB3_MOUSE
NC score	-0.000263 (rank : 118)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	898	Shared Neighborhood Hits	6
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB3_HUMAN
NC score	-0.000707 (rank : 119)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	918	Shared Neighborhood Hits	6
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ZN516_MOUSE
NC score	-0.001197 (rank : 120)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	1197	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN692_HUMAN
NC score	-0.001519 (rank : 121)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	808	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.