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Network neighborhood for query Sequence : AKA10_HUMAN

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AKA10_HUMAN
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AKA10_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
θ value	0 (rank : 2)	NC score	0.989098 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SNX13_MOUSE
θ value	1.87187e-05 (rank : 3)	NC score	0.292199 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	86	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

RGS14_HUMAN
θ value	7.1131e-05 (rank : 4)	NC score	0.340573 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS1_HUMAN
θ value	7.1131e-05 (rank : 5)	NC score	0.353834 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS1_MOUSE
θ value	0.00020696 (rank : 6)	NC score	0.349794 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS14_MOUSE
θ value	0.000270298 (rank : 7)	NC score	0.332121 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

SNX13_HUMAN
θ value	0.000270298 (rank : 8)	NC score	0.278625 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

RGS3_HUMAN
θ value	0.00035302 (rank : 9)	NC score	0.243992 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	1375	Shared Neighborhood Hits	41
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS17_HUMAN
θ value	0.000461057 (rank : 10)	NC score	0.340208 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS3_MOUSE
θ value	0.000602161 (rank : 11)	NC score	0.214783 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	1621	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RGS4_HUMAN
θ value	0.000602161 (rank : 12)	NC score	0.333105 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS17_MOUSE
θ value	0.00102713 (rank : 13)	NC score	0.336365 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS2_HUMAN
θ value	0.00228821 (rank : 14)	NC score	0.324833 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS2_MOUSE
θ value	0.00298849 (rank : 15)	NC score	0.323012 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	52	Shared Neighborhood Hits	34
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS13_HUMAN
θ value	0.00390308 (rank : 16)	NC score	0.333710 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS13_MOUSE
θ value	0.00390308 (rank : 17)	NC score	0.329662 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS20_MOUSE
θ value	0.00665767 (rank : 18)	NC score	0.327348 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS12_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.283339 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	333	Shared Neighborhood Hits	35
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS20_HUMAN
θ value	0.0148317 (rank : 20)	NC score	0.321678 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

SMC1A_MOUSE
θ value	0.0193708 (rank : 21)	NC score	0.041267 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	1384	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SNX14_HUMAN
θ value	0.0252991 (rank : 22)	NC score	0.164697 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
θ value	0.0252991 (rank : 23)	NC score	0.169050 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

RGS16_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.307672 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

SMC1A_HUMAN
θ value	0.0330416 (rank : 25)	NC score	0.041726 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	1346	Shared Neighborhood Hits	10
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

RGS8_HUMAN
θ value	0.0431538 (rank : 26)	NC score	0.311557 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS5_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.310048 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS19_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.311466 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS8_MOUSE
θ value	0.0736092 (rank : 29)	NC score	0.308825 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS10_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.308160 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS19_HUMAN
θ value	0.279714 (rank : 31)	NC score	0.301931 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

EP15_HUMAN
θ value	0.365318 (rank : 32)	NC score	0.048937 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	1021	Shared Neighborhood Hits	12
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

RGS10_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.301740 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

AXN1_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.227760 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

EP15_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.048131 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	820	Shared Neighborhood Hits	12
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

RGS16_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.286713 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	32
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

AXN2_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.193397 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

NFRKB_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.033016 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

RGS5_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.289020 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	52	Shared Neighborhood Hits	36
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

WNK2_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.011058 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	1407	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AXN2_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.195746 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

CHD9_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.009436 (rank : 63)
Query Neighborhood Hits	58	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

EP15R_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.031534 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	1083	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.030367 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EST1A_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.029447 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

TAXB1_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.014427 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	829	Shared Neighborhood Hits	10
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

PDE3B_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.009657 (rank : 62)
Query Neighborhood Hits	58	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q13370, O00639, Q14408	Gene names	PDE3B
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

RGS4_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.286402 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

WDR61_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.005448 (rank : 67)
Query Neighborhood Hits	58	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

CASC5_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.029259 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

RFWD2_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.007002 (rank : 66)
Query Neighborhood Hits	58	Target Neighborhood Hits	535	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

CASR_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.004825 (rank : 68)
Query Neighborhood Hits	58	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

K2C4_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.002807 (rank : 69)
Query Neighborhood Hits	58	Target Neighborhood Hits	521	Shared Neighborhood Hits	8
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

NFRKB_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.024822 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	393	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

POGK_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.008899 (rank : 65)
Query Neighborhood Hits	58	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P215, Q8TE07	Gene names	POGK, KIAA1513
Domain Architecture
Description	Pogo transposable element with KRAB domain (LST003/SLTP003).

POGK_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.008957 (rank : 64)
Query Neighborhood Hits	58	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TC5, Q8BPJ3, Q8C887	Gene names	Pogk, Kiaa1513
Domain Architecture
Description	Pogo transposable element with KRAB domain.

SRRM2_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.025807 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	1470	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TITIN_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.001532 (rank : 70)
Query Neighborhood Hits	58	Target Neighborhood Hits	2923	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AXN1_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.197124 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

RGS11_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.206760 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS18_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.260045 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS18_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.260845 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS6_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.181476 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

RGS6_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.192411 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS7_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.198055 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.197709 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS9_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.191485 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	64	Shared Neighborhood Hits	30
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.191187 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

SNX25_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.093042 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

ZCH10_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.057092 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	133	Shared Neighborhood Hits	1
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

Hits sorted by NC score

AKA10_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
NC score	0.989098 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

RGS1_HUMAN
NC score	0.353834 (rank : 3)	θ value	7.1131e-05 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS1_MOUSE
NC score	0.349794 (rank : 4)	θ value	0.00020696 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS14_HUMAN
NC score	0.340573 (rank : 5)	θ value	7.1131e-05 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS17_HUMAN
NC score	0.340208 (rank : 6)	θ value	0.000461057 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS17_MOUSE
NC score	0.336365 (rank : 7)	θ value	0.00102713 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS13_HUMAN
NC score	0.333710 (rank : 8)	θ value	0.00390308 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS4_HUMAN
NC score	0.333105 (rank : 9)	θ value	0.000602161 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS14_MOUSE
NC score	0.332121 (rank : 10)	θ value	0.000270298 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS13_MOUSE
NC score	0.329662 (rank : 11)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS20_MOUSE
NC score	0.327348 (rank : 12)	θ value	0.00665767 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS2_HUMAN
NC score	0.324833 (rank : 13)	θ value	0.00228821 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS2_MOUSE
NC score	0.323012 (rank : 14)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	52	Shared Neighborhood Hits	34
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS20_HUMAN
NC score	0.321678 (rank : 15)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS8_HUMAN
NC score	0.311557 (rank : 16)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS19_MOUSE
NC score	0.311466 (rank : 17)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS5_MOUSE
NC score	0.310048 (rank : 18)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS8_MOUSE
NC score	0.308825 (rank : 19)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS10_MOUSE
NC score	0.308160 (rank : 20)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS16_MOUSE
NC score	0.307672 (rank : 21)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS19_HUMAN
NC score	0.301931 (rank : 22)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS10_HUMAN
NC score	0.301740 (rank : 23)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

SNX13_MOUSE
NC score	0.292199 (rank : 24)	θ value	1.87187e-05 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	86	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

RGS5_HUMAN
NC score	0.289020 (rank : 25)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	52	Shared Neighborhood Hits	36
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS16_HUMAN
NC score	0.286713 (rank : 26)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	32
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS4_MOUSE
NC score	0.286402 (rank : 27)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS12_HUMAN
NC score	0.283339 (rank : 28)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	333	Shared Neighborhood Hits	35
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SNX13_HUMAN
NC score	0.278625 (rank : 29)	θ value	0.000270298 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

RGS18_MOUSE
NC score	0.260845 (rank : 30)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	58	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS18_HUMAN
NC score	0.260045 (rank : 31)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS3_HUMAN
NC score	0.243992 (rank : 32)	θ value	0.00035302 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	1375	Shared Neighborhood Hits	41
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

AXN1_MOUSE
NC score	0.227760 (rank : 33)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

RGS3_MOUSE
NC score	0.214783 (rank : 34)	θ value	0.000602161 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	1621	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RGS11_HUMAN
NC score	0.206760 (rank : 35)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS7_HUMAN
NC score	0.198055 (rank : 36)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	58	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_MOUSE
NC score	0.197709 (rank : 37)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	58	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

AXN1_HUMAN
NC score	0.197124 (rank : 38)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

AXN2_HUMAN
NC score	0.195746 (rank : 39)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN2_MOUSE
NC score	0.193397 (rank : 40)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

RGS6_MOUSE
NC score	0.192411 (rank : 41)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	58	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS9_HUMAN
NC score	0.191485 (rank : 42)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	58	Target Neighborhood Hits	64	Shared Neighborhood Hits	30
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_MOUSE
NC score	0.191187 (rank : 43)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS6_HUMAN
NC score	0.181476 (rank : 44)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	58	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

SNX14_MOUSE
NC score	0.169050 (rank : 45)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX14_HUMAN
NC score	0.164697 (rank : 46)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX25_HUMAN
NC score	0.093042 (rank : 47)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

ZCH10_MOUSE
NC score	0.057092 (rank : 48)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	58	Target Neighborhood Hits	133	Shared Neighborhood Hits	1
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

EP15_HUMAN
NC score	0.048937 (rank : 49)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	1021	Shared Neighborhood Hits	12
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
NC score	0.048131 (rank : 50)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	820	Shared Neighborhood Hits	12
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

SMC1A_HUMAN
NC score	0.041726 (rank : 51)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	1346	Shared Neighborhood Hits	10
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
NC score	0.041267 (rank : 52)	θ value	0.0193708 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	1384	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

NFRKB_HUMAN
NC score	0.033016 (rank : 53)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

EP15R_HUMAN
NC score	0.031534 (rank : 54)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	1083	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
NC score	0.030367 (rank : 55)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EST1A_HUMAN
NC score	0.029447 (rank : 56)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

CASC5_MOUSE
NC score	0.029259 (rank : 57)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

SRRM2_MOUSE
NC score	0.025807 (rank : 58)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	1470	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NFRKB_MOUSE
NC score	0.024822 (rank : 59)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	393	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

TAXB1_HUMAN
NC score	0.014427 (rank : 60)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	829	Shared Neighborhood Hits	10
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

WNK2_HUMAN
NC score	0.011058 (rank : 61)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	1407	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

PDE3B_HUMAN
NC score	0.009657 (rank : 62)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q13370, O00639, Q14408	Gene names	PDE3B
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

CHD9_HUMAN
NC score	0.009436 (rank : 63)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

POGK_MOUSE
NC score	0.008957 (rank : 64)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TC5, Q8BPJ3, Q8C887	Gene names	Pogk, Kiaa1513
Domain Architecture
Description	Pogo transposable element with KRAB domain.

POGK_HUMAN
NC score	0.008899 (rank : 65)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P215, Q8TE07	Gene names	POGK, KIAA1513
Domain Architecture
Description	Pogo transposable element with KRAB domain (LST003/SLTP003).

RFWD2_MOUSE
NC score	0.007002 (rank : 66)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	535	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

WDR61_MOUSE
NC score	0.005448 (rank : 67)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

CASR_HUMAN
NC score	0.004825 (rank : 68)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

K2C4_MOUSE
NC score	0.002807 (rank : 69)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	521	Shared Neighborhood Hits	8
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

TITIN_HUMAN
NC score	0.001532 (rank : 70)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	2923	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).