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Network neighborhood for query Sequence : RGS11_HUMAN

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RGS11_HUMAN
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RGS11_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS9_MOUSE
θ value	2.97304e-136 (rank : 2)	NC score	0.981415 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_HUMAN
θ value	3.28708e-135 (rank : 3)	NC score	0.981321 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	50
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS7_HUMAN
θ value	1.89267e-82 (rank : 4)	NC score	0.964253 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_MOUSE
θ value	2.47191e-82 (rank : 5)	NC score	0.963996 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS6_MOUSE
θ value	4.67263e-73 (rank : 6)	NC score	0.957923 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS6_HUMAN
θ value	1.27248e-70 (rank : 7)	NC score	0.948344 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

RGS19_HUMAN
θ value	2.20094e-22 (rank : 8)	NC score	0.868230 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS20_HUMAN
θ value	2.87452e-22 (rank : 9)	NC score	0.869944 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS1_HUMAN
θ value	1.86321e-21 (rank : 10)	NC score	0.868811 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	43
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS19_MOUSE
θ value	2.43343e-21 (rank : 11)	NC score	0.867916 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS20_MOUSE
θ value	2.43343e-21 (rank : 12)	NC score	0.869888 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS12_HUMAN
θ value	3.51386e-20 (rank : 13)	NC score	0.737060 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	333	Shared Neighborhood Hits	48
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS14_HUMAN
θ value	5.99374e-20 (rank : 14)	NC score	0.817982 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	77	Shared Neighborhood Hits	42
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS8_MOUSE
θ value	5.99374e-20 (rank : 15)	NC score	0.854671 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS3_HUMAN
θ value	1.02238e-19 (rank : 16)	NC score	0.602781 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	1375	Shared Neighborhood Hits	44
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS8_HUMAN
θ value	1.02238e-19 (rank : 17)	NC score	0.855389 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS18_HUMAN
θ value	1.74391e-19 (rank : 18)	NC score	0.857787 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	44	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS17_MOUSE
θ value	5.07402e-19 (rank : 19)	NC score	0.864513 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS17_HUMAN
θ value	6.62687e-19 (rank : 20)	NC score	0.865608 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS3_MOUSE
θ value	8.65492e-19 (rank : 21)	NC score	0.537198 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	1621	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RGS14_MOUSE
θ value	1.13037e-18 (rank : 22)	NC score	0.817883 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	55	Shared Neighborhood Hits	40
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS1_MOUSE
θ value	2.5182e-18 (rank : 23)	NC score	0.866421 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS18_MOUSE
θ value	3.28887e-18 (rank : 24)	NC score	0.852239 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS5_MOUSE
θ value	7.32683e-18 (rank : 25)	NC score	0.863064 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS5_HUMAN
θ value	3.63628e-17 (rank : 26)	NC score	0.856326 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	52	Shared Neighborhood Hits	42
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS10_HUMAN
θ value	1.058e-16 (rank : 27)	NC score	0.870100 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	57	Shared Neighborhood Hits	43
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS10_MOUSE
θ value	1.38178e-16 (rank : 28)	NC score	0.870717 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	57	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS4_HUMAN
θ value	1.38178e-16 (rank : 29)	NC score	0.847024 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS4_MOUSE
θ value	2.35696e-16 (rank : 30)	NC score	0.849714 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS13_HUMAN
θ value	3.07829e-16 (rank : 31)	NC score	0.851429 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS16_HUMAN
θ value	5.25075e-16 (rank : 32)	NC score	0.844977 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	40
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS13_MOUSE
θ value	1.52774e-15 (rank : 33)	NC score	0.846602 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS16_MOUSE
θ value	4.44505e-15 (rank : 34)	NC score	0.839533 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS2_MOUSE
θ value	1.29331e-14 (rank : 35)	NC score	0.838842 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	52	Shared Neighborhood Hits	41
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS2_HUMAN
θ value	2.88119e-14 (rank : 36)	NC score	0.839864 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	41
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

AXN2_HUMAN
θ value	1.69304e-06 (rank : 37)	NC score	0.557248 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN1_MOUSE
θ value	2.88788e-06 (rank : 38)	NC score	0.569785 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AXN2_MOUSE
θ value	2.88788e-06 (rank : 39)	NC score	0.551682 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

SNX13_HUMAN
θ value	4.92598e-06 (rank : 40)	NC score	0.313304 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	84	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX13_MOUSE
θ value	1.43324e-05 (rank : 41)	NC score	0.314744 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

PLEK_MOUSE
θ value	3.19293e-05 (rank : 42)	NC score	0.114629 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

AXN1_HUMAN
θ value	5.44631e-05 (rank : 43)	NC score	0.553728 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

DVL1L_HUMAN
θ value	0.000602161 (rank : 44)	NC score	0.125051 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

SNX25_HUMAN
θ value	0.000786445 (rank : 45)	NC score	0.236135 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

DVL1_MOUSE
θ value	0.00298849 (rank : 46)	NC score	0.124330 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_HUMAN
θ value	0.00390308 (rank : 47)	NC score	0.124282 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	158	Shared Neighborhood Hits	18
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

PLEK_HUMAN
θ value	0.00869519 (rank : 48)	NC score	0.088106 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

DVL3_HUMAN
θ value	0.0113563 (rank : 49)	NC score	0.144997 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	194	Shared Neighborhood Hits	20
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	0.0113563 (rank : 50)	NC score	0.145032 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL2_HUMAN
θ value	0.0736092 (rank : 51)	NC score	0.122897 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	0.0736092 (rank : 52)	NC score	0.122002 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PREX1_HUMAN
θ value	0.813845 (rank : 53)	NC score	0.042264 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

VRK3_MOUSE
θ value	1.06291 (rank : 54)	NC score	0.011271 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	342	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3G5, Q921W6	Gene names	Vrk3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

AMGO1_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.006615 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	353	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WK6, Q8IW71, Q9ULQ7	Gene names	AMIGO1, ALI2, AMIGO, KIAA1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

GBG5_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.020655 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P63218, P30670, Q5VX54, Q61015	Gene names	GNG5, GNGT5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-5 subunit precursor.

GBG5_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.020528 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q80SZ7, P30670, Q5I0W4, Q61015	Gene names	Gng5, Gngt5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-5 subunit precursor.

AMGO1_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.006167 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

ZN638_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.010352 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	343	Shared Neighborhood Hits	3
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

HIC1_MOUSE
θ value	4.03905 (rank : 60)	NC score	-0.001829 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	863	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

CXXC6_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.014183 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

GBG11_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.013118 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	P61952, P50152	Gene names	GNG11, GNGT11
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit precursor.

GBG11_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.013118 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	P61953, P50152, Q4QRN2	Gene names	Gng11, Gngt11
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit precursor.

TTLL4_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.005773 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

WN10A_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.001946 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZT5, Q96TA7, Q9H7S8	Gene names	WNT10A
Domain Architecture
Description	Protein Wnt-10a precursor.

AKAP1_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.009798 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.012196 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

HES2_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.006318 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y543, Q96EN4, Q9Y542	Gene names	HES2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

AKA10_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.206760 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.206377 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SNX14_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.050603 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.061325 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

Hits sorted by NC score

RGS11_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS9_MOUSE
NC score	0.981415 (rank : 2)	θ value	2.97304e-136 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_HUMAN
NC score	0.981321 (rank : 3)	θ value	3.28708e-135 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	50
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS7_HUMAN
NC score	0.964253 (rank : 4)	θ value	1.89267e-82 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_MOUSE
NC score	0.963996 (rank : 5)	θ value	2.47191e-82 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS6_MOUSE
NC score	0.957923 (rank : 6)	θ value	4.67263e-73 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS6_HUMAN
NC score	0.948344 (rank : 7)	θ value	1.27248e-70 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

RGS10_MOUSE
NC score	0.870717 (rank : 8)	θ value	1.38178e-16 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	57	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS10_HUMAN
NC score	0.870100 (rank : 9)	θ value	1.058e-16 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	57	Shared Neighborhood Hits	43
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS20_HUMAN
NC score	0.869944 (rank : 10)	θ value	2.87452e-22 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS20_MOUSE
NC score	0.869888 (rank : 11)	θ value	2.43343e-21 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS1_HUMAN
NC score	0.868811 (rank : 12)	θ value	1.86321e-21 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	43
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS19_HUMAN
NC score	0.868230 (rank : 13)	θ value	2.20094e-22 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS19_MOUSE
NC score	0.867916 (rank : 14)	θ value	2.43343e-21 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS1_MOUSE
NC score	0.866421 (rank : 15)	θ value	2.5182e-18 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS17_HUMAN
NC score	0.865608 (rank : 16)	θ value	6.62687e-19 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS17_MOUSE
NC score	0.864513 (rank : 17)	θ value	5.07402e-19 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS5_MOUSE
NC score	0.863064 (rank : 18)	θ value	7.32683e-18 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS18_HUMAN
NC score	0.857787 (rank : 19)	θ value	1.74391e-19 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	44	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS5_HUMAN
NC score	0.856326 (rank : 20)	θ value	3.63628e-17 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	52	Shared Neighborhood Hits	42
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS8_HUMAN
NC score	0.855389 (rank : 21)	θ value	1.02238e-19 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS8_MOUSE
NC score	0.854671 (rank : 22)	θ value	5.99374e-20 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS18_MOUSE
NC score	0.852239 (rank : 23)	θ value	3.28887e-18 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS13_HUMAN
NC score	0.851429 (rank : 24)	θ value	3.07829e-16 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS4_MOUSE
NC score	0.849714 (rank : 25)	θ value	2.35696e-16 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS4_HUMAN
NC score	0.847024 (rank : 26)	θ value	1.38178e-16 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS13_MOUSE
NC score	0.846602 (rank : 27)	θ value	1.52774e-15 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS16_HUMAN
NC score	0.844977 (rank : 28)	θ value	5.25075e-16 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	40
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS2_HUMAN
NC score	0.839864 (rank : 29)	θ value	2.88119e-14 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	41
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS16_MOUSE
NC score	0.839533 (rank : 30)	θ value	4.44505e-15 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS2_MOUSE
NC score	0.838842 (rank : 31)	θ value	1.29331e-14 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	52	Shared Neighborhood Hits	41
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS14_HUMAN
NC score	0.817982 (rank : 32)	θ value	5.99374e-20 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	77	Shared Neighborhood Hits	42
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS14_MOUSE
NC score	0.817883 (rank : 33)	θ value	1.13037e-18 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	55	Shared Neighborhood Hits	40
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS12_HUMAN
NC score	0.737060 (rank : 34)	θ value	3.51386e-20 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	333	Shared Neighborhood Hits	48
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS3_HUMAN
NC score	0.602781 (rank : 35)	θ value	1.02238e-19 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	1375	Shared Neighborhood Hits	44
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

AXN1_MOUSE
NC score	0.569785 (rank : 36)	θ value	2.88788e-06 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AXN2_HUMAN
NC score	0.557248 (rank : 37)	θ value	1.69304e-06 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN1_HUMAN
NC score	0.553728 (rank : 38)	θ value	5.44631e-05 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

AXN2_MOUSE
NC score	0.551682 (rank : 39)	θ value	2.88788e-06 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

RGS3_MOUSE
NC score	0.537198 (rank : 40)	θ value	8.65492e-19 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	1621	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SNX13_MOUSE
NC score	0.314744 (rank : 41)	θ value	1.43324e-05 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNX13_HUMAN
NC score	0.313304 (rank : 42)	θ value	4.92598e-06 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	84	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX25_HUMAN
NC score	0.236135 (rank : 43)	θ value	0.000786445 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

AKA10_HUMAN
NC score	0.206760 (rank : 44)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
NC score	0.206377 (rank : 45)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

DVL3_MOUSE
NC score	0.145032 (rank : 46)	θ value	0.0113563 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_HUMAN
NC score	0.144997 (rank : 47)	θ value	0.0113563 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	194	Shared Neighborhood Hits	20
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1L_HUMAN
NC score	0.125051 (rank : 48)	θ value	0.000602161 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_MOUSE
NC score	0.124330 (rank : 49)	θ value	0.00298849 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_HUMAN
NC score	0.124282 (rank : 50)	θ value	0.00390308 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	158	Shared Neighborhood Hits	18
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL2_HUMAN
NC score	0.122897 (rank : 51)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.122002 (rank : 52)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PLEK_MOUSE
NC score	0.114629 (rank : 53)	θ value	3.19293e-05 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK_HUMAN
NC score	0.088106 (rank : 54)	θ value	0.00869519 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

SNX14_MOUSE
NC score	0.061325 (rank : 55)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX14_HUMAN
NC score	0.050603 (rank : 56)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

PREX1_HUMAN
NC score	0.042264 (rank : 57)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

GBG5_HUMAN
NC score	0.020655 (rank : 58)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P63218, P30670, Q5VX54, Q61015	Gene names	GNG5, GNGT5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-5 subunit precursor.

GBG5_MOUSE
NC score	0.020528 (rank : 59)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q80SZ7, P30670, Q5I0W4, Q61015	Gene names	Gng5, Gngt5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-5 subunit precursor.

CXXC6_HUMAN
NC score	0.014183 (rank : 60)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

GBG11_HUMAN
NC score	0.013118 (rank : 61)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	P61952, P50152	Gene names	GNG11, GNGT11
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit precursor.

GBG11_MOUSE
NC score	0.013118 (rank : 62)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	P61953, P50152, Q4QRN2	Gene names	Gng11, Gngt11
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit precursor.

AKAP1_MOUSE
NC score	0.012196 (rank : 63)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

VRK3_MOUSE
NC score	0.011271 (rank : 64)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	342	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3G5, Q921W6	Gene names	Vrk3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

ZN638_HUMAN
NC score	0.010352 (rank : 65)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	343	Shared Neighborhood Hits	3
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

AKAP1_HUMAN
NC score	0.009798 (rank : 66)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AMGO1_HUMAN
NC score	0.006615 (rank : 67)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	353	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WK6, Q8IW71, Q9ULQ7	Gene names	AMIGO1, ALI2, AMIGO, KIAA1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

HES2_HUMAN
NC score	0.006318 (rank : 68)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y543, Q96EN4, Q9Y542	Gene names	HES2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

AMGO1_MOUSE
NC score	0.006167 (rank : 69)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

TTLL4_HUMAN
NC score	0.005773 (rank : 70)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

WN10A_HUMAN
NC score	0.001946 (rank : 71)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZT5, Q96TA7, Q9H7S8	Gene names	WNT10A
Domain Architecture
Description	Protein Wnt-10a precursor.

HIC1_MOUSE
NC score	-0.001829 (rank : 72)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	863	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).