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Network neighborhood for query Sequence : SNX14_HUMAN

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SNX14_HUMAN
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SNX14_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
θ value	0 (rank : 2)	NC score	0.994687 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX13_HUMAN
θ value	7.84624e-12 (rank : 3)	NC score	0.465029 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX25_HUMAN
θ value	4.0297e-08 (rank : 4)	NC score	0.471005 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

SNX19_HUMAN
θ value	1.99992e-07 (rank : 5)	NC score	0.422744 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	123	Shared Neighborhood Hits	28
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

SNX13_MOUSE
θ value	2.61198e-07 (rank : 6)	NC score	0.430484 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SGK3_HUMAN
θ value	3.41135e-07 (rank : 7)	NC score	0.066178 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	877	Shared Neighborhood Hits	37
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

SGK3_MOUSE
θ value	3.41135e-07 (rank : 8)	NC score	0.066736 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	882	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

PXK_MOUSE
θ value	4.45536e-07 (rank : 9)	NC score	0.361827 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	320	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

PXK_HUMAN
θ value	2.21117e-06 (rank : 10)	NC score	0.362189 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	216	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SNX9_HUMAN
θ value	4.92598e-06 (rank : 11)	NC score	0.301017 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	148	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SNX9_MOUSE
θ value	6.43352e-06 (rank : 12)	NC score	0.301328 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	141	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

SNX16_MOUSE
θ value	2.44474e-05 (rank : 13)	NC score	0.397007 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C080	Gene names	Snx16
Domain Architecture	No domain graphic available
Description	Sorting nexin-16.

SNX16_HUMAN
θ value	3.19293e-05 (rank : 14)	NC score	0.395912 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	P57768, Q8N4U3	Gene names	SNX16
Domain Architecture
Description	Sorting nexin-16.

SNX8_MOUSE
θ value	9.29e-05 (rank : 15)	NC score	0.360985 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CFD4, Q8BLI6, Q8BUQ7	Gene names	Snx8
Domain Architecture	No domain graphic available
Description	Sorting nexin-8.

AXN1_MOUSE
θ value	0.000158464 (rank : 16)	NC score	0.167967 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

SNX2_MOUSE
θ value	0.00020696 (rank : 17)	NC score	0.291221 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	156	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CWK8, Q3UKW3, Q9CQV0	Gene names	Snx2
Domain Architecture
Description	Sorting nexin-2.

SNX7_MOUSE
θ value	0.00020696 (rank : 18)	NC score	0.309673 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CY18	Gene names	Snx7
Domain Architecture
Description	Sorting nexin-7.

SNX8_HUMAN
θ value	0.000270298 (rank : 19)	NC score	0.348611 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5X2, Q96I67	Gene names	SNX8
Domain Architecture
Description	Sorting nexin-8.

SNX7_HUMAN
θ value	0.00035302 (rank : 20)	NC score	0.306681 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UNH6, Q86U82, Q8WVD4, Q96FW9, Q9Y3Z7	Gene names	SNX7
Domain Architecture
Description	Sorting nexin-7.

SNX2_HUMAN
θ value	0.000786445 (rank : 21)	NC score	0.284777 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	151	Shared Neighborhood Hits	35
SwissProt Accessions	O60749, O43650, P82862, Q53XK8, Q597H6, Q9BTS8	Gene names	SNX2, TRG9
Domain Architecture
Description	Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9).

AXN1_HUMAN
θ value	0.00175202 (rank : 22)	NC score	0.152386 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

SNX11_HUMAN
θ value	0.00175202 (rank : 23)	NC score	0.272648 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5W9, Q9H885	Gene names	SNX11
Domain Architecture
Description	Sorting nexin-11.

SNX11_MOUSE
θ value	0.00228821 (rank : 24)	NC score	0.268090 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q91WL6, Q3V3A6	Gene names	Snx11
Domain Architecture	No domain graphic available
Description	Sorting nexin-11.

SNX1_HUMAN
θ value	0.0113563 (rank : 25)	NC score	0.273794 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	Q13596, O60750, O60751	Gene names	SNX1
Domain Architecture
Description	Sorting nexin-1.

SNX1_MOUSE
θ value	0.0113563 (rank : 26)	NC score	0.270444 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WV80, Q9EQZ9	Gene names	Snx1
Domain Architecture
Description	Sorting nexin-1.

AKA10_HUMAN
θ value	0.0252991 (rank : 27)	NC score	0.164697 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
θ value	0.0252991 (rank : 28)	NC score	0.163551 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SNX20_MOUSE
θ value	0.0563607 (rank : 29)	NC score	0.260833 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D2Y5, Q544B6	Gene names	Snx20
Domain Architecture	No domain graphic available
Description	Sorting nexin-20.

SNX4_MOUSE
θ value	0.0563607 (rank : 30)	NC score	0.259100 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YJ2	Gene names	Snx4
Domain Architecture	No domain graphic available
Description	Sorting nexin-4.

SNX23_HUMAN
θ value	0.125558 (rank : 31)	NC score	0.042979 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	944	Shared Neighborhood Hits	29
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

RGS2_HUMAN
θ value	0.163984 (rank : 32)	NC score	0.089119 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS2_MOUSE
θ value	0.21417 (rank : 33)	NC score	0.087469 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	15
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

SNX17_MOUSE
θ value	0.21417 (rank : 34)	NC score	0.155176 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BVL3, Q8R0N8	Gene names	Snx17
Domain Architecture	No domain graphic available
Description	Sorting nexin-17.

SNX18_HUMAN
θ value	0.21417 (rank : 35)	NC score	0.236492 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	207	Shared Neighborhood Hits	37
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	0.21417 (rank : 36)	NC score	0.237150 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	198	Shared Neighborhood Hits	36
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

NCF4_MOUSE
θ value	0.279714 (rank : 37)	NC score	0.102292 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

RGS1_MOUSE
θ value	0.279714 (rank : 38)	NC score	0.099521 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

SNX17_HUMAN
θ value	0.279714 (rank : 39)	NC score	0.149257 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	Q15036, Q53HN7, Q6IAS3	Gene names	SNX17, KIAA0064
Domain Architecture
Description	Sorting nexin-17.

SNX27_HUMAN
θ value	0.365318 (rank : 40)	NC score	0.200791 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	Q96L92	Gene names	SNX27
Domain Architecture
Description	Sorting nexin-27.

SNX4_HUMAN
θ value	0.365318 (rank : 41)	NC score	0.242529 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	O95219	Gene names	SNX4
Domain Architecture
Description	Sorting nexin-4.

NCF4_HUMAN
θ value	0.47712 (rank : 42)	NC score	0.101985 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

RGS1_HUMAN
θ value	0.47712 (rank : 43)	NC score	0.098595 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

K1C23_MOUSE
θ value	0.62314 (rank : 44)	NC score	0.011666 (rank : 101)
Query Neighborhood Hits	77	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PS0	Gene names	Krt23, Haik1, Krt1-23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

ADCY9_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.038827 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	O60503, O60273, Q4ZHT9, Q4ZIR5, Q9BWT4, Q9UGP2	Gene names	ADCY9, KIAA0520
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9).

AMNLS_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.053324 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q99JB7, Q5I0U1, Q99MP9	Gene names	Amn
Domain Architecture	No domain graphic available
Description	Amnionless protein precursor.

CAB45_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.040552 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q61112, Q61113	Gene names	Sdf4, Cab45
Domain Architecture	No domain graphic available
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

GUC2D_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.018643 (rank : 97)
Query Neighborhood Hits	77	Target Neighborhood Hits	715	Shared Neighborhood Hits	6
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

P3C2A_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.035074 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

RGS3_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.050250 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	1375	Shared Neighborhood Hits	22
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS5_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.076130 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RPGF1_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.031173 (rank : 90)
Query Neighborhood Hits	77	Target Neighborhood Hits	262	Shared Neighborhood Hits	3
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

ARSF_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.015640 (rank : 98)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

COMDA_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.052732 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6G5, Q9P077	Gene names	COMMD10
Domain Architecture	No domain graphic available
Description	COMM domain-containing protein 10.

SNX21_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.173519 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q969T3, Q5JZH6, Q9BR16	Gene names	SNX21, C20orf161, SNXL
Domain Architecture
Description	Sorting nexin-21 (Sorting nexin L) (SNX-L).

ADCY9_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.032054 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P51830, Q61279	Gene names	Adcy9
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9) (Adenylyl cyclase type 10) (ACTP10).

AXN2_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.089893 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

GUC2F_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.011537 (rank : 102)
Query Neighborhood Hits	77	Target Neighborhood Hits	740	Shared Neighborhood Hits	6
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

SNX12_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.185494 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UMY4, Q8WUG9	Gene names	SNX12
Domain Architecture
Description	Sorting nexin-12.

TMPS3_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.007612 (rank : 106)
Query Neighborhood Hits	77	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.007592 (rank : 107)
Query Neighborhood Hits	77	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

JIP3_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.009470 (rank : 104)
Query Neighborhood Hits	77	Target Neighborhood Hits	759	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

K1C23_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.008288 (rank : 105)
Query Neighborhood Hits	77	Target Neighborhood Hits	312	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C075, Q9NUR6	Gene names	KRT23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

KS6C1_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.027890 (rank : 92)
Query Neighborhood Hits	77	Target Neighborhood Hits	700	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

PLD1_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.020518 (rank : 95)
Query Neighborhood Hits	77	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

RGS7_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.053786 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

NUFP1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.024272 (rank : 94)
Query Neighborhood Hits	77	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

P3C2A_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.029594 (rank : 91)
Query Neighborhood Hits	77	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

PLD1_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.020506 (rank : 96)
Query Neighborhood Hits	77	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

RABE1_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.007192 (rank : 109)
Query Neighborhood Hits	77	Target Neighborhood Hits	1105	Shared Neighborhood Hits	9
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

AMNLS_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.036566 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXJ7, Q6UX83	Gene names	AMN
Domain Architecture	No domain graphic available
Description	Amnionless protein precursor.

CEP63_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.007262 (rank : 108)
Query Neighborhood Hits	77	Target Neighborhood Hits	1005	Shared Neighborhood Hits	10
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

DYH5_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.012262 (rank : 100)
Query Neighborhood Hits	77	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

GBP2_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.010027 (rank : 103)
Query Neighborhood Hits	77	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

MYO9B_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.001867 (rank : 110)
Query Neighborhood Hits	77	Target Neighborhood Hits	641	Shared Neighborhood Hits	4
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P3C2B_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.027665 (rank : 93)
Query Neighborhood Hits	77	Target Neighborhood Hits	148	Shared Neighborhood Hits	14
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

TLE6_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.012270 (rank : 99)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

AXN2_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.073765 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

RGS10_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.062647 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS10_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.063571 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS11_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.050603 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS13_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.055971 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS17_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.056328 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS17_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.057166 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS18_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.053502 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS18_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.054530 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS19_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.051194 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS19_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.053205 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS20_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.058064 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS20_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.058759 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS4_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.058818 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS4_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.056844 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS5_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.060567 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	14
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS7_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.051947 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS8_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.057739 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS8_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.057577 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

SNX10_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.130474 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5X0	Gene names	SNX10
Domain Architecture
Description	Sorting nexin-10.

SNX10_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.131615 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CWT3, Q8C1E0	Gene names	Snx10
Domain Architecture	No domain graphic available
Description	Sorting nexin-10.

SNX12_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.169203 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	O70493, Q9D0N3	Gene names	Snx12
Domain Architecture
Description	Sorting nexin-12 (SDP8 protein).

SNX15_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.072575 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRS6, Q9NRS5	Gene names	SNX15
Domain Architecture
Description	Sorting nexin-15.

SNX15_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.074565 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	Q91WE1	Gene names	Snx15
Domain Architecture	No domain graphic available
Description	Sorting nexin-15.

SNX22_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.063101 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q96L94, Q9H844	Gene names	SNX22
Domain Architecture
Description	Sorting nexin-22.

SNX24_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.089963 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y343, Q6UY33	Gene names	SNX24
Domain Architecture
Description	Sorting nexin-24.

SNX24_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.090512 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CRB0	Gene names	Snx24
Domain Architecture	No domain graphic available
Description	Sorting nexin-24.

SNX3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.169235 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	O60493, O60718, Q5JXJ7, Q5JXJ8, Q96AP9, Q9C0J5, Q9NU45	Gene names	SNX3
Domain Architecture
Description	Sorting nexin-3 (Protein SDP3).

SNX3_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.169108 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	O70492	Gene names	Snx3
Domain Architecture
Description	Sorting nexin-3 (SDP3 protein).

SNX5_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.063528 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5X3, Q52LC4, Q9BWP0	Gene names	SNX5
Domain Architecture
Description	Sorting nexin-5.

SNX5_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.064190 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D8U8, Q543N9	Gene names	Snx5
Domain Architecture
Description	Sorting nexin-5.

SNX6_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.054672 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNH7, Q9Y449	Gene names	SNX6
Domain Architecture
Description	Sorting nexin-6 (TRAF4-associated factor 2).

SNX6_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.054680 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8X1	Gene names	Snx6
Domain Architecture	No domain graphic available
Description	Sorting nexin-6.

Hits sorted by NC score

SNX14_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
NC score	0.994687 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX25_HUMAN
NC score	0.471005 (rank : 3)	θ value	4.0297e-08 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

SNX13_HUMAN
NC score	0.465029 (rank : 4)	θ value	7.84624e-12 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX13_MOUSE
NC score	0.430484 (rank : 5)	θ value	2.61198e-07 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNX19_HUMAN
NC score	0.422744 (rank : 6)	θ value	1.99992e-07 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	123	Shared Neighborhood Hits	28
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

SNX16_MOUSE
NC score	0.397007 (rank : 7)	θ value	2.44474e-05 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C080	Gene names	Snx16
Domain Architecture	No domain graphic available
Description	Sorting nexin-16.

SNX16_HUMAN
NC score	0.395912 (rank : 8)	θ value	3.19293e-05 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	P57768, Q8N4U3	Gene names	SNX16
Domain Architecture
Description	Sorting nexin-16.

PXK_HUMAN
NC score	0.362189 (rank : 9)	θ value	2.21117e-06 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	216	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

PXK_MOUSE
NC score	0.361827 (rank : 10)	θ value	4.45536e-07 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	320	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SNX8_MOUSE
NC score	0.360985 (rank : 11)	θ value	9.29e-05 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CFD4, Q8BLI6, Q8BUQ7	Gene names	Snx8
Domain Architecture	No domain graphic available
Description	Sorting nexin-8.

SNX8_HUMAN
NC score	0.348611 (rank : 12)	θ value	0.000270298 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5X2, Q96I67	Gene names	SNX8
Domain Architecture
Description	Sorting nexin-8.

SNX7_MOUSE
NC score	0.309673 (rank : 13)	θ value	0.00020696 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CY18	Gene names	Snx7
Domain Architecture
Description	Sorting nexin-7.

SNX7_HUMAN
NC score	0.306681 (rank : 14)	θ value	0.00035302 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UNH6, Q86U82, Q8WVD4, Q96FW9, Q9Y3Z7	Gene names	SNX7
Domain Architecture
Description	Sorting nexin-7.

SNX9_MOUSE
NC score	0.301328 (rank : 15)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	141	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

SNX9_HUMAN
NC score	0.301017 (rank : 16)	θ value	4.92598e-06 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	148	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SNX2_MOUSE
NC score	0.291221 (rank : 17)	θ value	0.00020696 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	156	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CWK8, Q3UKW3, Q9CQV0	Gene names	Snx2
Domain Architecture
Description	Sorting nexin-2.

SNX2_HUMAN
NC score	0.284777 (rank : 18)	θ value	0.000786445 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	151	Shared Neighborhood Hits	35
SwissProt Accessions	O60749, O43650, P82862, Q53XK8, Q597H6, Q9BTS8	Gene names	SNX2, TRG9
Domain Architecture
Description	Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9).

SNX1_HUMAN
NC score	0.273794 (rank : 19)	θ value	0.0113563 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	Q13596, O60750, O60751	Gene names	SNX1
Domain Architecture
Description	Sorting nexin-1.

SNX11_HUMAN
NC score	0.272648 (rank : 20)	θ value	0.00175202 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5W9, Q9H885	Gene names	SNX11
Domain Architecture
Description	Sorting nexin-11.

SNX1_MOUSE
NC score	0.270444 (rank : 21)	θ value	0.0113563 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WV80, Q9EQZ9	Gene names	Snx1
Domain Architecture
Description	Sorting nexin-1.

SNX11_MOUSE
NC score	0.268090 (rank : 22)	θ value	0.00228821 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q91WL6, Q3V3A6	Gene names	Snx11
Domain Architecture	No domain graphic available
Description	Sorting nexin-11.

SNX20_MOUSE
NC score	0.260833 (rank : 23)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D2Y5, Q544B6	Gene names	Snx20
Domain Architecture	No domain graphic available
Description	Sorting nexin-20.

SNX4_MOUSE
NC score	0.259100 (rank : 24)	θ value	0.0563607 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YJ2	Gene names	Snx4
Domain Architecture	No domain graphic available
Description	Sorting nexin-4.

SNX4_HUMAN
NC score	0.242529 (rank : 25)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	O95219	Gene names	SNX4
Domain Architecture
Description	Sorting nexin-4.

SNX18_MOUSE
NC score	0.237150 (rank : 26)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	198	Shared Neighborhood Hits	36
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_HUMAN
NC score	0.236492 (rank : 27)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	207	Shared Neighborhood Hits	37
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX27_HUMAN
NC score	0.200791 (rank : 28)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	Q96L92	Gene names	SNX27
Domain Architecture
Description	Sorting nexin-27.

SNX12_HUMAN
NC score	0.185494 (rank : 29)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UMY4, Q8WUG9	Gene names	SNX12
Domain Architecture
Description	Sorting nexin-12.

SNX21_HUMAN
NC score	0.173519 (rank : 30)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q969T3, Q5JZH6, Q9BR16	Gene names	SNX21, C20orf161, SNXL
Domain Architecture
Description	Sorting nexin-21 (Sorting nexin L) (SNX-L).

SNX3_HUMAN
NC score	0.169235 (rank : 31)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	77	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	O60493, O60718, Q5JXJ7, Q5JXJ8, Q96AP9, Q9C0J5, Q9NU45	Gene names	SNX3
Domain Architecture
Description	Sorting nexin-3 (Protein SDP3).

SNX12_MOUSE
NC score	0.169203 (rank : 32)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	O70493, Q9D0N3	Gene names	Snx12
Domain Architecture
Description	Sorting nexin-12 (SDP8 protein).

SNX3_MOUSE
NC score	0.169108 (rank : 33)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	O70492	Gene names	Snx3
Domain Architecture
Description	Sorting nexin-3 (SDP3 protein).

AXN1_MOUSE
NC score	0.167967 (rank : 34)	θ value	0.000158464 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AKA10_HUMAN
NC score	0.164697 (rank : 35)	θ value	0.0252991 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
NC score	0.163551 (rank : 36)	θ value	0.0252991 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SNX17_MOUSE
NC score	0.155176 (rank : 37)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BVL3, Q8R0N8	Gene names	Snx17
Domain Architecture	No domain graphic available
Description	Sorting nexin-17.

AXN1_HUMAN
NC score	0.152386 (rank : 38)	θ value	0.00175202 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

SNX17_HUMAN
NC score	0.149257 (rank : 39)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	Q15036, Q53HN7, Q6IAS3	Gene names	SNX17, KIAA0064
Domain Architecture
Description	Sorting nexin-17.

SNX10_MOUSE
NC score	0.131615 (rank : 40)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CWT3, Q8C1E0	Gene names	Snx10
Domain Architecture	No domain graphic available
Description	Sorting nexin-10.

SNX10_HUMAN
NC score	0.130474 (rank : 41)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5X0	Gene names	SNX10
Domain Architecture
Description	Sorting nexin-10.

NCF4_MOUSE
NC score	0.102292 (rank : 42)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_HUMAN
NC score	0.101985 (rank : 43)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

RGS1_MOUSE
NC score	0.099521 (rank : 44)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS1_HUMAN
NC score	0.098595 (rank : 45)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

SNX24_MOUSE
NC score	0.090512 (rank : 46)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	77	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CRB0	Gene names	Snx24
Domain Architecture	No domain graphic available
Description	Sorting nexin-24.

SNX24_HUMAN
NC score	0.089963 (rank : 47)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y343, Q6UY33	Gene names	SNX24
Domain Architecture
Description	Sorting nexin-24.

AXN2_HUMAN
NC score	0.089893 (rank : 48)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

RGS2_HUMAN
NC score	0.089119 (rank : 49)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS2_MOUSE
NC score	0.087469 (rank : 50)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	15
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS5_HUMAN
NC score	0.076130 (rank : 51)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

SNX15_MOUSE
NC score	0.074565 (rank : 52)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	77	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	Q91WE1	Gene names	Snx15
Domain Architecture	No domain graphic available
Description	Sorting nexin-15.

AXN2_MOUSE
NC score	0.073765 (rank : 53)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

SNX15_HUMAN
NC score	0.072575 (rank : 54)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	77	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRS6, Q9NRS5	Gene names	SNX15
Domain Architecture
Description	Sorting nexin-15.

SGK3_MOUSE
NC score	0.066736 (rank : 55)	θ value	3.41135e-07 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	882	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

SGK3_HUMAN
NC score	0.066178 (rank : 56)	θ value	3.41135e-07 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	877	Shared Neighborhood Hits	37
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

SNX5_MOUSE
NC score	0.064190 (rank : 57)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	77	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D8U8, Q543N9	Gene names	Snx5
Domain Architecture
Description	Sorting nexin-5.

RGS10_MOUSE
NC score	0.063571 (rank : 58)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

SNX5_HUMAN
NC score	0.063528 (rank : 59)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5X3, Q52LC4, Q9BWP0	Gene names	SNX5
Domain Architecture
Description	Sorting nexin-5.

SNX22_HUMAN
NC score	0.063101 (rank : 60)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q96L94, Q9H844	Gene names	SNX22
Domain Architecture
Description	Sorting nexin-22.

RGS10_HUMAN
NC score	0.062647 (rank : 61)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS5_MOUSE
NC score	0.060567 (rank : 62)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	14
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS4_HUMAN
NC score	0.058818 (rank : 63)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	77	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS20_MOUSE
NC score	0.058759 (rank : 64)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS20_HUMAN
NC score	0.058064 (rank : 65)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS8_HUMAN
NC score	0.057739 (rank : 66)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS8_MOUSE
NC score	0.057577 (rank : 67)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS17_MOUSE
NC score	0.057166 (rank : 68)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS4_MOUSE
NC score	0.056844 (rank : 69)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS17_HUMAN
NC score	0.056328 (rank : 70)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS13_HUMAN
NC score	0.055971 (rank : 71)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

SNX6_MOUSE
NC score	0.054680 (rank : 72)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8X1	Gene names	Snx6
Domain Architecture	No domain graphic available
Description	Sorting nexin-6.

SNX6_HUMAN
NC score	0.054672 (rank : 73)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNH7, Q9Y449	Gene names	SNX6
Domain Architecture
Description	Sorting nexin-6 (TRAF4-associated factor 2).

RGS18_MOUSE
NC score	0.054530 (rank : 74)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS7_MOUSE
NC score	0.053786 (rank : 75)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS18_HUMAN
NC score	0.053502 (rank : 76)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

AMNLS_MOUSE
NC score	0.053324 (rank : 77)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q99JB7, Q5I0U1, Q99MP9	Gene names	Amn
Domain Architecture	No domain graphic available
Description	Amnionless protein precursor.

RGS19_MOUSE
NC score	0.053205 (rank : 78)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

COMDA_HUMAN
NC score	0.052732 (rank : 79)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6G5, Q9P077	Gene names	COMMD10
Domain Architecture	No domain graphic available
Description	COMM domain-containing protein 10.

RGS7_HUMAN
NC score	0.051947 (rank : 80)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS19_HUMAN
NC score	0.051194 (rank : 81)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS11_HUMAN
NC score	0.050603 (rank : 82)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS3_HUMAN
NC score	0.050250 (rank : 83)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	1375	Shared Neighborhood Hits	22
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SNX23_HUMAN
NC score	0.042979 (rank : 84)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	944	Shared Neighborhood Hits	29
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

CAB45_MOUSE
NC score	0.040552 (rank : 85)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q61112, Q61113	Gene names	Sdf4, Cab45
Domain Architecture	No domain graphic available
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

ADCY9_HUMAN
NC score	0.038827 (rank : 86)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	O60503, O60273, Q4ZHT9, Q4ZIR5, Q9BWT4, Q9UGP2	Gene names	ADCY9, KIAA0520
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9).

AMNLS_HUMAN
NC score	0.036566 (rank : 87)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXJ7, Q6UX83	Gene names	AMN
Domain Architecture	No domain graphic available
Description	Amnionless protein precursor.

P3C2A_HUMAN
NC score	0.035074 (rank : 88)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

ADCY9_MOUSE
NC score	0.032054 (rank : 89)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P51830, Q61279	Gene names	Adcy9
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9) (Adenylyl cyclase type 10) (ACTP10).

RPGF1_HUMAN
NC score	0.031173 (rank : 90)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	262	Shared Neighborhood Hits	3
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

P3C2A_MOUSE
NC score	0.029594 (rank : 91)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

KS6C1_MOUSE
NC score	0.027890 (rank : 92)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	700	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

P3C2B_HUMAN
NC score	0.027665 (rank : 93)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	148	Shared Neighborhood Hits	14
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

NUFP1_HUMAN
NC score	0.024272 (rank : 94)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PLD1_HUMAN
NC score	0.020518 (rank : 95)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

PLD1_MOUSE
NC score	0.020506 (rank : 96)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

GUC2D_HUMAN
NC score	0.018643 (rank : 97)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	715	Shared Neighborhood Hits	6
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

ARSF_HUMAN
NC score	0.015640 (rank : 98)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

TLE6_HUMAN
NC score	0.012270 (rank : 99)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

DYH5_HUMAN
NC score	0.012262 (rank : 100)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

K1C23_MOUSE
NC score	0.011666 (rank : 101)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PS0	Gene names	Krt23, Haik1, Krt1-23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

GUC2F_HUMAN
NC score	0.011537 (rank : 102)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	740	Shared Neighborhood Hits	6
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GBP2_HUMAN
NC score	0.010027 (rank : 103)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

JIP3_MOUSE
NC score	0.009470 (rank : 104)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	759	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

K1C23_HUMAN
NC score	0.008288 (rank : 105)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	312	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C075, Q9NUR6	Gene names	KRT23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

TMPS3_HUMAN
NC score	0.007612 (rank : 106)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
NC score	0.007592 (rank : 107)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

CEP63_HUMAN
NC score	0.007262 (rank : 108)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	1005	Shared Neighborhood Hits	10
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

RABE1_MOUSE
NC score	0.007192 (rank : 109)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	1105	Shared Neighborhood Hits	9
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

MYO9B_HUMAN
NC score	0.001867 (rank : 110)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	641	Shared Neighborhood Hits	4
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).