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Network neighborhood for query Sequence : ARSF_HUMAN

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ARSF_HUMAN
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARSD_HUMAN
θ value	0 (rank : 1)	NC score	0.989766 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

ARSF_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

ARSE_HUMAN
θ value	4.84403e-179 (rank : 3)	NC score	0.988060 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	P51690, Q53FT2, Q53FU8	Gene names	ARSE
Domain Architecture
Description	Arylsulfatase E precursor (EC 3.1.6.-) (ASE).

STS_HUMAN
θ value	2.04937e-153 (rank : 4)	NC score	0.984712 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P08842	Gene names	STS
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

STS_MOUSE
θ value	5.24793e-133 (rank : 5)	NC score	0.985086 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSG_MOUSE
θ value	9.76566e-63 (rank : 6)	NC score	0.901530 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSG_HUMAN
θ value	5.73848e-55 (rank : 7)	NC score	0.883807 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSA_HUMAN
θ value	1.79215e-40 (rank : 8)	NC score	0.876283 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

GA6S_HUMAN
θ value	2.42216e-37 (rank : 9)	NC score	0.888837 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

ARSA_MOUSE
θ value	4.28545e-26 (rank : 10)	NC score	0.865975 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

ARSB_HUMAN
θ value	2.06002e-20 (rank : 11)	NC score	0.765696 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	24
SwissProt Accessions	P15848	Gene names	ARSB
Domain Architecture
Description	Arylsulfatase B precursor (EC 3.1.6.12) (ASB) (N-acetylgalactosamine- 4-sulfatase) (G4S).

ARSJ_HUMAN
θ value	3.88503e-19 (rank : 12)	NC score	0.734757 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB0, Q5FWE4, Q6UWT9	Gene names	ARSJ
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSJ_MOUSE
θ value	3.88503e-19 (rank : 13)	NC score	0.731274 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSI_HUMAN
θ value	3.28887e-18 (rank : 14)	NC score	0.743468 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

IDS_HUMAN
θ value	1.09485e-13 (rank : 15)	NC score	0.693335 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

IDS_MOUSE
θ value	3.18553e-13 (rank : 16)	NC score	0.694429 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

SPHM_HUMAN
θ value	4.76016e-09 (rank : 17)	NC score	0.672543 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	P51688	Gene names	SGSH, HSS
Domain Architecture
Description	N-sulphoglucosamine sulphohydrolase precursor (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase).

ARSK_HUMAN
θ value	4.0297e-08 (rank : 18)	NC score	0.569080 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UWY0, Q8N3Q8	Gene names	ARSK, TSULF
Domain Architecture	No domain graphic available
Description	Arylsulfatase K precursor (EC 3.1.6.-) (ASK) (Telethon sulfatase).

SULF2_MOUSE
θ value	1.69304e-06 (rank : 19)	NC score	0.421455 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

SULF1_HUMAN
θ value	6.43352e-06 (rank : 20)	NC score	0.427167 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

SULF1_MOUSE
θ value	6.43352e-06 (rank : 21)	NC score	0.430093 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

SULF2_HUMAN
θ value	1.09739e-05 (rank : 22)	NC score	0.412084 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWU5, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3	Gene names	SULF2, KIAA1247
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (HSulf-2).

GL6S_HUMAN
θ value	7.1131e-05 (rank : 23)	NC score	0.488919 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15586	Gene names	GNS
Domain Architecture
Description	N-acetylglucosamine-6-sulfatase precursor (EC 3.1.6.14) (G6S) (Glucosamine-6-sulfatase).

ENPP2_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.029185 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

SNX14_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.015640 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

ELA3B_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.002233 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ENPP2_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.029261 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

JPH3_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.027636 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXH2, Q8N471, Q9HDC3, Q9HDC4	Gene names	JPH3, JP3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

JPH3_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.027704 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ET77, Q9EQZ2	Gene names	Jph3, Jp3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

DNS2A_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.008119 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P56542, O55053	Gene names	Dnase2, Dnase2a, Dnl2
Domain Architecture
Description	Deoxyribonuclease-2-alpha precursor (EC 3.1.22.1) (Deoxyribonuclease II alpha) (DNase II alpha) (Acid DNase) (Lysosomal DNase II).

ENPP1_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.018391 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP7_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.052134 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

MLL3_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.001272 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	1399	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

Hits sorted by NC score

ARSF_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

ARSD_HUMAN
NC score	0.989766 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

ARSE_HUMAN
NC score	0.988060 (rank : 3)	θ value	4.84403e-179 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	P51690, Q53FT2, Q53FU8	Gene names	ARSE
Domain Architecture
Description	Arylsulfatase E precursor (EC 3.1.6.-) (ASE).

STS_MOUSE
NC score	0.985086 (rank : 4)	θ value	5.24793e-133 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

STS_HUMAN
NC score	0.984712 (rank : 5)	θ value	2.04937e-153 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P08842	Gene names	STS
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSG_MOUSE
NC score	0.901530 (rank : 6)	θ value	9.76566e-63 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

GA6S_HUMAN
NC score	0.888837 (rank : 7)	θ value	2.42216e-37 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

ARSG_HUMAN
NC score	0.883807 (rank : 8)	θ value	5.73848e-55 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSA_HUMAN
NC score	0.876283 (rank : 9)	θ value	1.79215e-40 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

ARSA_MOUSE
NC score	0.865975 (rank : 10)	θ value	4.28545e-26 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

ARSB_HUMAN
NC score	0.765696 (rank : 11)	θ value	2.06002e-20 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	24
SwissProt Accessions	P15848	Gene names	ARSB
Domain Architecture
Description	Arylsulfatase B precursor (EC 3.1.6.12) (ASB) (N-acetylgalactosamine- 4-sulfatase) (G4S).

ARSI_HUMAN
NC score	0.743468 (rank : 12)	θ value	3.28887e-18 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

ARSJ_HUMAN
NC score	0.734757 (rank : 13)	θ value	3.88503e-19 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB0, Q5FWE4, Q6UWT9	Gene names	ARSJ
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSJ_MOUSE
NC score	0.731274 (rank : 14)	θ value	3.88503e-19 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

IDS_MOUSE
NC score	0.694429 (rank : 15)	θ value	3.18553e-13 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

IDS_HUMAN
NC score	0.693335 (rank : 16)	θ value	1.09485e-13 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

SPHM_HUMAN
NC score	0.672543 (rank : 17)	θ value	4.76016e-09 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	P51688	Gene names	SGSH, HSS
Domain Architecture
Description	N-sulphoglucosamine sulphohydrolase precursor (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase).

ARSK_HUMAN
NC score	0.569080 (rank : 18)	θ value	4.0297e-08 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UWY0, Q8N3Q8	Gene names	ARSK, TSULF
Domain Architecture	No domain graphic available
Description	Arylsulfatase K precursor (EC 3.1.6.-) (ASK) (Telethon sulfatase).

GL6S_HUMAN
NC score	0.488919 (rank : 19)	θ value	7.1131e-05 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15586	Gene names	GNS
Domain Architecture
Description	N-acetylglucosamine-6-sulfatase precursor (EC 3.1.6.14) (G6S) (Glucosamine-6-sulfatase).

SULF1_MOUSE
NC score	0.430093 (rank : 20)	θ value	6.43352e-06 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

SULF1_HUMAN
NC score	0.427167 (rank : 21)	θ value	6.43352e-06 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

SULF2_MOUSE
NC score	0.421455 (rank : 22)	θ value	1.69304e-06 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

SULF2_HUMAN
NC score	0.412084 (rank : 23)	θ value	1.09739e-05 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWU5, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3	Gene names	SULF2, KIAA1247
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (HSulf-2).

ENPP7_HUMAN
NC score	0.052134 (rank : 24)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

ENPP2_MOUSE
NC score	0.029261 (rank : 25)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
NC score	0.029185 (rank : 26)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

JPH3_MOUSE
NC score	0.027704 (rank : 27)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ET77, Q9EQZ2	Gene names	Jph3, Jp3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

JPH3_HUMAN
NC score	0.027636 (rank : 28)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXH2, Q8N471, Q9HDC3, Q9HDC4	Gene names	JPH3, JP3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

ENPP1_MOUSE
NC score	0.018391 (rank : 29)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

SNX14_HUMAN
NC score	0.015640 (rank : 30)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

DNS2A_MOUSE
NC score	0.008119 (rank : 31)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P56542, O55053	Gene names	Dnase2, Dnase2a, Dnl2
Domain Architecture
Description	Deoxyribonuclease-2-alpha precursor (EC 3.1.22.1) (Deoxyribonuclease II alpha) (DNase II alpha) (Acid DNase) (Lysosomal DNase II).

ELA3B_HUMAN
NC score	0.002233 (rank : 32)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

MLL3_MOUSE
NC score	0.001272 (rank : 33)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	1399	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).