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Network neighborhood for query Sequence : SULF1_MOUSE

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SULF1_MOUSE
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SULF1_HUMAN
θ value	0 (rank : 1)	NC score	0.995784 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

SULF1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

SULF2_HUMAN
θ value	0 (rank : 3)	NC score	0.992538 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWU5, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3	Gene names	SULF2, KIAA1247
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (HSulf-2).

SULF2_MOUSE
θ value	0 (rank : 4)	NC score	0.992310 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

GL6S_HUMAN
θ value	8.20983e-86 (rank : 5)	NC score	0.940430 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15586	Gene names	GNS
Domain Architecture
Description	N-acetylglucosamine-6-sulfatase precursor (EC 3.1.6.14) (G6S) (Glucosamine-6-sulfatase).

ARSK_HUMAN
θ value	1.63225e-17 (rank : 6)	NC score	0.708321 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UWY0, Q8N3Q8	Gene names	ARSK, TSULF
Domain Architecture	No domain graphic available
Description	Arylsulfatase K precursor (EC 3.1.6.-) (ASK) (Telethon sulfatase).

ARSA_MOUSE
θ value	2.43908e-13 (rank : 7)	NC score	0.543593 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

IDS_HUMAN
θ value	3.18553e-13 (rank : 8)	NC score	0.572773 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

IDS_MOUSE
θ value	1.2105e-12 (rank : 9)	NC score	0.576594 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

GA6S_HUMAN
θ value	1.58096e-12 (rank : 10)	NC score	0.550384 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

ARSJ_HUMAN
θ value	5.08577e-11 (rank : 11)	NC score	0.503731 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB0, Q5FWE4, Q6UWT9	Gene names	ARSJ
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSJ_MOUSE
θ value	1.9326e-10 (rank : 12)	NC score	0.500429 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSI_HUMAN
θ value	4.30538e-10 (rank : 13)	NC score	0.498255 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

SPHM_HUMAN
θ value	6.21693e-09 (rank : 14)	NC score	0.570549 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	P51688	Gene names	SGSH, HSS
Domain Architecture
Description	N-sulphoglucosamine sulphohydrolase precursor (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase).

ARSG_MOUSE
θ value	1.80886e-08 (rank : 15)	NC score	0.497857 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSB_HUMAN
θ value	2.36244e-08 (rank : 16)	NC score	0.485250 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	25	Shared Neighborhood Hits	24
SwissProt Accessions	P15848	Gene names	ARSB
Domain Architecture
Description	Arylsulfatase B precursor (EC 3.1.6.12) (ASB) (N-acetylgalactosamine- 4-sulfatase) (G4S).

STS_HUMAN
θ value	1.99992e-07 (rank : 17)	NC score	0.458657 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P08842	Gene names	STS
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

STS_MOUSE
θ value	4.45536e-07 (rank : 18)	NC score	0.438328 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSF_HUMAN
θ value	6.43352e-06 (rank : 19)	NC score	0.430093 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

ARSA_HUMAN
θ value	8.40245e-06 (rank : 20)	NC score	0.495712 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

ARSD_HUMAN
θ value	3.19293e-05 (rank : 21)	NC score	0.413782 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

ARSG_HUMAN
θ value	5.44631e-05 (rank : 22)	NC score	0.446981 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSE_HUMAN
θ value	7.1131e-05 (rank : 23)	NC score	0.408854 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P51690, Q53FT2, Q53FU8	Gene names	ARSE
Domain Architecture
Description	Arylsulfatase E precursor (EC 3.1.6.-) (ASE).

PHLB2_MOUSE
θ value	0.365318 (rank : 24)	NC score	0.019105 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	1016	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

ZFP46_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.006202 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	744	Shared Neighborhood Hits	11
SwissProt Accessions	Q03309	Gene names	Zfp46, Mlz-4
Domain Architecture	No domain graphic available
Description	Zinc finger protein 46 (Zfp-46) (Zinc finger protein MLZ-4).

ZN436_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.006194 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	756	Shared Neighborhood Hits	11
SwissProt Accessions	Q9C0F3, Q658I9	Gene names	ZNF436, KIAA1710
Domain Architecture
Description	Zinc finger protein 436.

ZN436_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.006239 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	756	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BPP0, Q69ZC6, Q8BQC2	Gene names	Znf436, Kiaa1710, Zfp46
Domain Architecture	No domain graphic available
Description	Zinc finger protein 436 (Zinc finger protein 46).

ZN565_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.005453 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	743	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N9K5, Q6NUS2	Gene names	ZNF565
Domain Architecture	No domain graphic available
Description	Zinc finger protein 565.

ENPP7_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.039212 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

ZN347_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.005538 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	756	Shared Neighborhood Hits	12
SwissProt Accessions	Q96SE7, Q8TCN1	Gene names	ZNF347, ZNF1111
Domain Architecture
Description	Zinc finger protein 347 (Zinc finger protein 1111).

CF170_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.027863 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NH3, Q6ZMY4, Q6ZUR7, Q8NB47	Gene names	C6orf170
Domain Architecture	No domain graphic available
Description	Protein C6orf170.

CP135_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.007652 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	1278	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TRAK2_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.020412 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	476	Shared Neighborhood Hits	8
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

CE152_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.011078 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	976	Shared Neighborhood Hits	11
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

TCF17_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.004826 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	797	Shared Neighborhood Hits	11
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

BAZ1B_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.007502 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	701	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

MTSS1_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.024065 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	504	Shared Neighborhood Hits	4
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.020426 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	592	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

SMC2_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.010855 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	1131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

ITSN1_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.007847 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	1669	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

TNR11_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.014645 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

ZN479_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.004522 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	746	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JC4	Gene names	ZNF479
Domain Architecture
Description	Zinc finger protein 479 (Zinc finger protein Kr19) (HKr19).

ATF4_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.011679 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P18848, Q9UH31	Gene names	ATF4
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-4 (Activating transcription factor 4) (DNA-binding protein TAXREB67) (Cyclic AMP response element-binding protein 2) (CREB2).

ZFP30_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.004612 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	737	Shared Neighborhood Hits	11
SwissProt Accessions	Q60585, Q9CRV9	Gene names	Zfp30
Domain Architecture	No domain graphic available
Description	Zinc finger protein 30 (Zfp-30).

ZN655_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.004901 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	784	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N720, Q8IV00, Q8TA89, Q96EZ3	Gene names	ZNF655, VIK
Domain Architecture	No domain graphic available
Description	Zinc finger protein 655 (Vav-interacting Krueppel-like protein).

CCD46_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.001709 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	1405	Shared Neighborhood Hits	11
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

FLIP1_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.006950 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	1405	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

PCBP2_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.004435 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

RO52_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.000928 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

SLIT3_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.000088 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	682	Shared Neighborhood Hits	3
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TEP1_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.012878 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	371	Shared Neighborhood Hits	5
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

ZFP14_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.004467 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	743	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCL3	Gene names	ZFP14, KIAA1559
Domain Architecture
Description	Zinc finger protein 14 homolog (Zfp-14).

Hits sorted by NC score

SULF1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

SULF1_HUMAN
NC score	0.995784 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

SULF2_HUMAN
NC score	0.992538 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWU5, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3	Gene names	SULF2, KIAA1247
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (HSulf-2).

SULF2_MOUSE
NC score	0.992310 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

GL6S_HUMAN
NC score	0.940430 (rank : 5)	θ value	8.20983e-86 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15586	Gene names	GNS
Domain Architecture
Description	N-acetylglucosamine-6-sulfatase precursor (EC 3.1.6.14) (G6S) (Glucosamine-6-sulfatase).

ARSK_HUMAN
NC score	0.708321 (rank : 6)	θ value	1.63225e-17 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UWY0, Q8N3Q8	Gene names	ARSK, TSULF
Domain Architecture	No domain graphic available
Description	Arylsulfatase K precursor (EC 3.1.6.-) (ASK) (Telethon sulfatase).

IDS_MOUSE
NC score	0.576594 (rank : 7)	θ value	1.2105e-12 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

IDS_HUMAN
NC score	0.572773 (rank : 8)	θ value	3.18553e-13 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

SPHM_HUMAN
NC score	0.570549 (rank : 9)	θ value	6.21693e-09 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	P51688	Gene names	SGSH, HSS
Domain Architecture
Description	N-sulphoglucosamine sulphohydrolase precursor (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase).

GA6S_HUMAN
NC score	0.550384 (rank : 10)	θ value	1.58096e-12 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

ARSA_MOUSE
NC score	0.543593 (rank : 11)	θ value	2.43908e-13 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

ARSJ_HUMAN
NC score	0.503731 (rank : 12)	θ value	5.08577e-11 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB0, Q5FWE4, Q6UWT9	Gene names	ARSJ
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSJ_MOUSE
NC score	0.500429 (rank : 13)	θ value	1.9326e-10 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSI_HUMAN
NC score	0.498255 (rank : 14)	θ value	4.30538e-10 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

ARSG_MOUSE
NC score	0.497857 (rank : 15)	θ value	1.80886e-08 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSA_HUMAN
NC score	0.495712 (rank : 16)	θ value	8.40245e-06 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

ARSB_HUMAN
NC score	0.485250 (rank : 17)	θ value	2.36244e-08 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	25	Shared Neighborhood Hits	24
SwissProt Accessions	P15848	Gene names	ARSB
Domain Architecture
Description	Arylsulfatase B precursor (EC 3.1.6.12) (ASB) (N-acetylgalactosamine- 4-sulfatase) (G4S).

STS_HUMAN
NC score	0.458657 (rank : 18)	θ value	1.99992e-07 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P08842	Gene names	STS
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSG_HUMAN
NC score	0.446981 (rank : 19)	θ value	5.44631e-05 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

STS_MOUSE
NC score	0.438328 (rank : 20)	θ value	4.45536e-07 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSF_HUMAN
NC score	0.430093 (rank : 21)	θ value	6.43352e-06 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

ARSD_HUMAN
NC score	0.413782 (rank : 22)	θ value	3.19293e-05 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

ARSE_HUMAN
NC score	0.408854 (rank : 23)	θ value	7.1131e-05 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P51690, Q53FT2, Q53FU8	Gene names	ARSE
Domain Architecture
Description	Arylsulfatase E precursor (EC 3.1.6.-) (ASE).

ENPP7_HUMAN
NC score	0.039212 (rank : 24)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

CF170_HUMAN
NC score	0.027863 (rank : 25)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NH3, Q6ZMY4, Q6ZUR7, Q8NB47	Gene names	C6orf170
Domain Architecture	No domain graphic available
Description	Protein C6orf170.

MTSS1_HUMAN
NC score	0.024065 (rank : 26)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	504	Shared Neighborhood Hits	4
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
NC score	0.020426 (rank : 27)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	592	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

TRAK2_HUMAN
NC score	0.020412 (rank : 28)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	476	Shared Neighborhood Hits	8
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

PHLB2_MOUSE
NC score	0.019105 (rank : 29)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	1016	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

TNR11_HUMAN
NC score	0.014645 (rank : 30)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TEP1_HUMAN
NC score	0.012878 (rank : 31)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	371	Shared Neighborhood Hits	5
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

ATF4_HUMAN
NC score	0.011679 (rank : 32)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P18848, Q9UH31	Gene names	ATF4
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-4 (Activating transcription factor 4) (DNA-binding protein TAXREB67) (Cyclic AMP response element-binding protein 2) (CREB2).

CE152_HUMAN
NC score	0.011078 (rank : 33)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	976	Shared Neighborhood Hits	11
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

SMC2_MOUSE
NC score	0.010855 (rank : 34)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	1131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

ITSN1_MOUSE
NC score	0.007847 (rank : 35)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	1669	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CP135_MOUSE
NC score	0.007652 (rank : 36)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	1278	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

BAZ1B_HUMAN
NC score	0.007502 (rank : 37)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	701	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

FLIP1_HUMAN
NC score	0.006950 (rank : 38)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	1405	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

ZN436_MOUSE
NC score	0.006239 (rank : 39)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	756	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BPP0, Q69ZC6, Q8BQC2	Gene names	Znf436, Kiaa1710, Zfp46
Domain Architecture	No domain graphic available
Description	Zinc finger protein 436 (Zinc finger protein 46).

ZFP46_MOUSE
NC score	0.006202 (rank : 40)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	744	Shared Neighborhood Hits	11
SwissProt Accessions	Q03309	Gene names	Zfp46, Mlz-4
Domain Architecture	No domain graphic available
Description	Zinc finger protein 46 (Zfp-46) (Zinc finger protein MLZ-4).

ZN436_HUMAN
NC score	0.006194 (rank : 41)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	756	Shared Neighborhood Hits	11
SwissProt Accessions	Q9C0F3, Q658I9	Gene names	ZNF436, KIAA1710
Domain Architecture
Description	Zinc finger protein 436.

ZN347_HUMAN
NC score	0.005538 (rank : 42)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	756	Shared Neighborhood Hits	12
SwissProt Accessions	Q96SE7, Q8TCN1	Gene names	ZNF347, ZNF1111
Domain Architecture
Description	Zinc finger protein 347 (Zinc finger protein 1111).

ZN565_HUMAN
NC score	0.005453 (rank : 43)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	743	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N9K5, Q6NUS2	Gene names	ZNF565
Domain Architecture	No domain graphic available
Description	Zinc finger protein 565.

ZN655_HUMAN
NC score	0.004901 (rank : 44)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	784	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N720, Q8IV00, Q8TA89, Q96EZ3	Gene names	ZNF655, VIK
Domain Architecture	No domain graphic available
Description	Zinc finger protein 655 (Vav-interacting Krueppel-like protein).

TCF17_HUMAN
NC score	0.004826 (rank : 45)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	797	Shared Neighborhood Hits	11
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

ZFP30_MOUSE
NC score	0.004612 (rank : 46)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	737	Shared Neighborhood Hits	11
SwissProt Accessions	Q60585, Q9CRV9	Gene names	Zfp30
Domain Architecture	No domain graphic available
Description	Zinc finger protein 30 (Zfp-30).

ZN479_HUMAN
NC score	0.004522 (rank : 47)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	746	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JC4	Gene names	ZNF479
Domain Architecture
Description	Zinc finger protein 479 (Zinc finger protein Kr19) (HKr19).

ZFP14_HUMAN
NC score	0.004467 (rank : 48)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	743	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCL3	Gene names	ZFP14, KIAA1559
Domain Architecture
Description	Zinc finger protein 14 homolog (Zfp-14).

PCBP2_MOUSE
NC score	0.004435 (rank : 49)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

CCD46_MOUSE
NC score	0.001709 (rank : 50)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	1405	Shared Neighborhood Hits	11
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

RO52_HUMAN
NC score	0.000928 (rank : 51)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

SLIT3_HUMAN
NC score	0.000088 (rank : 52)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	682	Shared Neighborhood Hits	3
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).