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Network neighborhood for query Sequence : STS_MOUSE

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STS_MOUSE
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STS_HUMAN
θ value	0 (rank : 1)	NC score	0.989093 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P08842	Gene names	STS
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

STS_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSD_HUMAN
θ value	4.90052e-139 (rank : 3)	NC score	0.983551 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

ARSE_HUMAN
θ value	2.0589e-137 (rank : 4)	NC score	0.984378 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	P51690, Q53FT2, Q53FU8	Gene names	ARSE
Domain Architecture
Description	Arylsulfatase E precursor (EC 3.1.6.-) (ASE).

ARSF_HUMAN
θ value	5.24793e-133 (rank : 5)	NC score	0.985086 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

ARSG_MOUSE
θ value	4.24587e-58 (rank : 6)	NC score	0.907727 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSA_HUMAN
θ value	5.19021e-56 (rank : 7)	NC score	0.901070 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

ARSG_HUMAN
θ value	2.49495e-50 (rank : 8)	NC score	0.891148 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSA_MOUSE
θ value	1.788e-48 (rank : 9)	NC score	0.894491 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

GA6S_HUMAN
θ value	1.32909e-35 (rank : 10)	NC score	0.897291 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

ARSI_HUMAN
θ value	2.43343e-21 (rank : 11)	NC score	0.753443 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

IDS_MOUSE
θ value	4.58923e-20 (rank : 12)	NC score	0.724038 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

ARSB_HUMAN
θ value	3.88503e-19 (rank : 13)	NC score	0.773252 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	24
SwissProt Accessions	P15848	Gene names	ARSB
Domain Architecture
Description	Arylsulfatase B precursor (EC 3.1.6.12) (ASB) (N-acetylgalactosamine- 4-sulfatase) (G4S).

ARSJ_HUMAN
θ value	3.88503e-19 (rank : 14)	NC score	0.742895 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB0, Q5FWE4, Q6UWT9	Gene names	ARSJ
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

IDS_HUMAN
θ value	8.65492e-19 (rank : 15)	NC score	0.720770 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

ARSJ_MOUSE
θ value	1.47631e-18 (rank : 16)	NC score	0.739372 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

SPHM_HUMAN
θ value	6.21693e-09 (rank : 17)	NC score	0.685663 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	P51688	Gene names	SGSH, HSS
Domain Architecture
Description	N-sulphoglucosamine sulphohydrolase precursor (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase).

SULF1_HUMAN
θ value	3.41135e-07 (rank : 18)	NC score	0.434989 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

SULF1_MOUSE
θ value	4.45536e-07 (rank : 19)	NC score	0.438328 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

ARSK_HUMAN
θ value	9.92553e-07 (rank : 20)	NC score	0.576320 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UWY0, Q8N3Q8	Gene names	ARSK, TSULF
Domain Architecture	No domain graphic available
Description	Arylsulfatase K precursor (EC 3.1.6.-) (ASK) (Telethon sulfatase).

SULF2_MOUSE
θ value	2.44474e-05 (rank : 21)	NC score	0.427282 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

SULF2_HUMAN
θ value	5.44631e-05 (rank : 22)	NC score	0.418465 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWU5, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3	Gene names	SULF2, KIAA1247
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (HSulf-2).

GL6S_HUMAN
θ value	0.000786445 (rank : 23)	NC score	0.494342 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15586	Gene names	GNS
Domain Architecture
Description	N-acetylglucosamine-6-sulfatase precursor (EC 3.1.6.14) (G6S) (Glucosamine-6-sulfatase).

FILA_HUMAN
θ value	0.0431538 (rank : 24)	NC score	0.026916 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	685	Shared Neighborhood Hits	2
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

APBB3_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.021465 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

VIPR2_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.009446 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

APBB3_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.019402 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

CLPX_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.012866 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

VIPR2_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.008405 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

ENPP1_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.017278 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.028335 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

RBL1_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.008428 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q64701	Gene names	Rbl1
Domain Architecture
Description	Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (PRB1) (P107).

ENPP7_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.050659 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

GPR35_HUMAN
θ value	6.88961 (rank : 34)	NC score	-0.000057 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	630	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC97, O43495, Q86UH4	Gene names	GPR35
Domain Architecture
Description	Probable G-protein coupled receptor 35.

RNH2C_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.030095 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQ18, Q8R1N2	Gene names	Rnaseh2c, Ayp1
Domain Architecture	No domain graphic available
Description	Ribonuclease H2 subunit C (RNase H2 subunit C) (Ribonuclease HI subunit C).

ENPP2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.027605 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

HNRPM_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.007275 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	210	Shared Neighborhood Hits	3
SwissProt Accessions	P52272, Q15584, Q8WZ44, Q96H56, Q9BWL9, Q9Y492	Gene names	HNRPM
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein M (hnRNP M).

HNRPM_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.007258 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0E1, Q6P1B2, Q99JQ0	Gene names	Hnrpm
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein M (hnRNP M).

Hits sorted by NC score

STS_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

STS_HUMAN
NC score	0.989093 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	P08842	Gene names	STS
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

ARSF_HUMAN
NC score	0.985086 (rank : 3)	θ value	5.24793e-133 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

ARSE_HUMAN
NC score	0.984378 (rank : 4)	θ value	2.0589e-137 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	P51690, Q53FT2, Q53FU8	Gene names	ARSE
Domain Architecture
Description	Arylsulfatase E precursor (EC 3.1.6.-) (ASE).

ARSD_HUMAN
NC score	0.983551 (rank : 5)	θ value	4.90052e-139 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

ARSG_MOUSE
NC score	0.907727 (rank : 6)	θ value	4.24587e-58 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSA_HUMAN
NC score	0.901070 (rank : 7)	θ value	5.19021e-56 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

GA6S_HUMAN
NC score	0.897291 (rank : 8)	θ value	1.32909e-35 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P34059, Q86VK3	Gene names	GALNS
Domain Architecture
Description	N-acetylgalactosamine-6-sulfatase precursor (EC 3.1.6.4) (N- acetylgalactosamine-6-sulfate sulfatase) (Galactose-6-sulfate sulfatase) (GalNAc6S sulfatase) (Chondroitinsulfatase) (Chondroitinase).

ARSA_MOUSE
NC score	0.894491 (rank : 9)	θ value	1.788e-48 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

ARSG_HUMAN
NC score	0.891148 (rank : 10)	θ value	2.49495e-50 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

ARSB_HUMAN
NC score	0.773252 (rank : 11)	θ value	3.88503e-19 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	24
SwissProt Accessions	P15848	Gene names	ARSB
Domain Architecture
Description	Arylsulfatase B precursor (EC 3.1.6.12) (ASB) (N-acetylgalactosamine- 4-sulfatase) (G4S).

ARSI_HUMAN
NC score	0.753443 (rank : 12)	θ value	2.43343e-21 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

ARSJ_HUMAN
NC score	0.742895 (rank : 13)	θ value	3.88503e-19 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FYB0, Q5FWE4, Q6UWT9	Gene names	ARSJ
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

ARSJ_MOUSE
NC score	0.739372 (rank : 14)	θ value	1.47631e-18 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

IDS_MOUSE
NC score	0.724038 (rank : 15)	θ value	4.58923e-20 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q08890, Q3TM30	Gene names	Ids
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase).

IDS_HUMAN
NC score	0.720770 (rank : 16)	θ value	8.65492e-19 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P22304, Q14604	Gene names	IDS
Domain Architecture
Description	Iduronate 2-sulfatase precursor (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain].

SPHM_HUMAN
NC score	0.685663 (rank : 17)	θ value	6.21693e-09 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	P51688	Gene names	SGSH, HSS
Domain Architecture
Description	N-sulphoglucosamine sulphohydrolase precursor (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase).

ARSK_HUMAN
NC score	0.576320 (rank : 18)	θ value	9.92553e-07 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UWY0, Q8N3Q8	Gene names	ARSK, TSULF
Domain Architecture	No domain graphic available
Description	Arylsulfatase K precursor (EC 3.1.6.-) (ASK) (Telethon sulfatase).

GL6S_HUMAN
NC score	0.494342 (rank : 19)	θ value	0.000786445 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P15586	Gene names	GNS
Domain Architecture
Description	N-acetylglucosamine-6-sulfatase precursor (EC 3.1.6.14) (G6S) (Glucosamine-6-sulfatase).

SULF1_MOUSE
NC score	0.438328 (rank : 20)	θ value	4.45536e-07 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

SULF1_HUMAN
NC score	0.434989 (rank : 21)	θ value	3.41135e-07 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

SULF2_MOUSE
NC score	0.427282 (rank : 22)	θ value	2.44474e-05 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

SULF2_HUMAN
NC score	0.418465 (rank : 23)	θ value	5.44631e-05 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWU5, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3	Gene names	SULF2, KIAA1247
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (HSulf-2).

ENPP7_HUMAN
NC score	0.050659 (rank : 24)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

RNH2C_MOUSE
NC score	0.030095 (rank : 25)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQ18, Q8R1N2	Gene names	Rnaseh2c, Ayp1
Domain Architecture	No domain graphic available
Description	Ribonuclease H2 subunit C (RNase H2 subunit C) (Ribonuclease HI subunit C).

ENPP2_MOUSE
NC score	0.028335 (rank : 26)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
NC score	0.027605 (rank : 27)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

FILA_HUMAN
NC score	0.026916 (rank : 28)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	685	Shared Neighborhood Hits	2
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

APBB3_HUMAN
NC score	0.021465 (rank : 29)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
NC score	0.019402 (rank : 30)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

ENPP1_MOUSE
NC score	0.017278 (rank : 31)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

CLPX_MOUSE
NC score	0.012866 (rank : 32)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

VIPR2_MOUSE
NC score	0.009446 (rank : 33)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

RBL1_MOUSE
NC score	0.008428 (rank : 34)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q64701	Gene names	Rbl1
Domain Architecture
Description	Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (PRB1) (P107).

VIPR2_HUMAN
NC score	0.008405 (rank : 35)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

HNRPM_HUMAN
NC score	0.007275 (rank : 36)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	210	Shared Neighborhood Hits	3
SwissProt Accessions	P52272, Q15584, Q8WZ44, Q96H56, Q9BWL9, Q9Y492	Gene names	HNRPM
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein M (hnRNP M).

HNRPM_MOUSE
NC score	0.007258 (rank : 37)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0E1, Q6P1B2, Q99JQ0	Gene names	Hnrpm
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein M (hnRNP M).

GPR35_HUMAN
NC score	-0.000057 (rank : 38)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	630	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC97, O43495, Q86UH4	Gene names	GPR35
Domain Architecture
Description	Probable G-protein coupled receptor 35.