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Network neighborhood for query Sequence : ENPP1_MOUSE

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ENPP1_MOUSE
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ENPP1_HUMAN
θ value	0 (rank : 1)	NC score	0.993516 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
θ value	0 (rank : 3)	NC score	0.973729 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	61	Shared Neighborhood Hits	25
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_MOUSE
θ value	0 (rank : 4)	NC score	0.974011 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP3_HUMAN
θ value	0 (rank : 5)	NC score	0.988548 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP5_MOUSE
θ value	4.84666e-62 (rank : 6)	NC score	0.889448 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQG7, Q921P7	Gene names	Enpp5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP5_HUMAN
θ value	2.03627e-60 (rank : 7)	NC score	0.889650 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJA9, Q6UX49	Gene names	ENPP5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP6_HUMAN
θ value	1.46268e-50 (rank : 8)	NC score	0.871948 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UWR7, Q96M57	Gene names	ENPP6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP6_MOUSE
θ value	4.70527e-49 (rank : 9)	NC score	0.869544 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGN3, Q4VAH5	Gene names	Enpp6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP7_HUMAN
θ value	2.18568e-46 (rank : 10)	NC score	0.886554 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

PRG4_MOUSE
θ value	8.11959e-09 (rank : 11)	NC score	0.201006 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	624	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
θ value	3.08544e-08 (rank : 12)	NC score	0.179535 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	764	Shared Neighborhood Hits	13
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PP11_HUMAN
θ value	0.000270298 (rank : 13)	NC score	0.310137 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

VTNC_MOUSE
θ value	0.00869519 (rank : 14)	NC score	0.154871 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

SUSD2_HUMAN
θ value	0.0330416 (rank : 15)	NC score	0.107802 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TINAG_HUMAN
θ value	0.0563607 (rank : 16)	NC score	0.086801 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

VTNC_HUMAN
θ value	0.0563607 (rank : 17)	NC score	0.146320 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

KRA54_HUMAN
θ value	0.0736092 (rank : 18)	NC score	0.035641 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	270	Shared Neighborhood Hits	14
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

CECR1_HUMAN
θ value	0.125558 (rank : 19)	NC score	0.053067 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZK5, Q96K41	Gene names	CECR1
Domain Architecture
Description	Cat eye syndrome critical region protein 1 precursor.

PIGG_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.159566 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

PIGO_HUMAN
θ value	0.163984 (rank : 21)	NC score	0.159645 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TEQ8, Q6P154, Q6UX80, Q8TDS8, Q96CS9, Q9BVN9, Q9Y4B0	Gene names	PIGO
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

PIGO_MOUSE
θ value	0.163984 (rank : 22)	NC score	0.152679 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JJI6, Q9CRY2	Gene names	Pigo
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

PIGN_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.091681 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O95427, Q7L8F8, Q8TC01, Q9NT05	Gene names	PIGN, MCD4
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) (MCD4 homolog).

PIGN_MOUSE
θ value	0.21417 (rank : 24)	NC score	0.100305 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

TENR_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.024852 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	526	Shared Neighborhood Hits	25
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

KRA58_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.035212 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	324	Shared Neighborhood Hits	17
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

SUSD2_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.090766 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	104	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SACS_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.020951 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

TENR_MOUSE
θ value	0.813845 (rank : 29)	NC score	0.023532 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	531	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

KRA53_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.024344 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	331	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

NUCGL_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.064605 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2C4	Gene names	ENDOGL1, ENGL
Domain Architecture
Description	Endonuclease G-like 1 (EC 3.1.30.-) (Endo G-like).

KRA47_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.026446 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA94_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.029742 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA57_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.025738 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ERGI1_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.025954 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q969X5, Q9H0L0, Q9H2J2, Q9ULN9	Gene names	ERGIC1, ERGIC32, KIAA1181
Domain Architecture	No domain graphic available
Description	Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER- Golgi intermediate compartment 32 kDa protein) (ERGIC-32).

ERGI1_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.025930 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DC16	Gene names	Ergic1, Ergic32
Domain Architecture	No domain graphic available
Description	Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER- Golgi intermediate compartment 32 kDa protein) (ERGIC-32).

KRA93_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.024569 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KR104_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.015245 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	313	Shared Neighborhood Hits	16
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR107_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.019903 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	330	Shared Neighborhood Hits	22
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR510_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.016331 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

NTNG2_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.007762 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	276	Shared Neighborhood Hits	11
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

JAG1_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.010620 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	518	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KR10A_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.022785 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	232	Shared Neighborhood Hits	20
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

LRP4_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.010732 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	351	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

NUCG_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.025124 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	O08600	Gene names	Endog
Domain Architecture
Description	Endonuclease G, mitochondrial precursor (EC 3.1.30.-) (Endo G).

SSPO_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.011804 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	800	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STS_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.017278 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

TENA_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.021154 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	631	Shared Neighborhood Hits	30
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

ADAM9_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.005216 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	243	Shared Neighborhood Hits	18
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

CUBN_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.006634 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	477	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

EMR2_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.004403 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	345	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FBLN3_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.006828 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	293	Shared Neighborhood Hits	12
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.006612 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

KRA59_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.050219 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LRP4_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.010420 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	355	Shared Neighborhood Hits	17
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

NUCG_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.023741 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q14249, Q9BSP2	Gene names	ENDOG
Domain Architecture
Description	Endonuclease G, mitochondrial precursor (EC 3.1.30.-) (Endo G).

TSP2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.006090 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	352	Shared Neighborhood Hits	20
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADAM9_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.005324 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	325	Shared Neighborhood Hits	21
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ARSA_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.028839 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

ARSF_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.018391 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

DSRAD_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.006042 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

GP153_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.005343 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0Z9, Q80T37, Q8CFK0	Gene names	Gpr153, Pgr1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

KRA98_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.018128 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

ST1C2_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.003241 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D939, Q3UNA9, Q8R210	Gene names	Sult1c2, Sult1c1
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-).

VEGFD_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.006805 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P97946	Gene names	Figf, Vegfd
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

Hits sorted by NC score

ENPP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_HUMAN
NC score	0.993516 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP3_HUMAN
NC score	0.988548 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_MOUSE
NC score	0.974011 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
NC score	0.973729 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	61	Shared Neighborhood Hits	25
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP5_HUMAN
NC score	0.889650 (rank : 6)	θ value	2.03627e-60 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJA9, Q6UX49	Gene names	ENPP5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP5_MOUSE
NC score	0.889448 (rank : 7)	θ value	4.84666e-62 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQG7, Q921P7	Gene names	Enpp5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP7_HUMAN
NC score	0.886554 (rank : 8)	θ value	2.18568e-46 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

ENPP6_HUMAN
NC score	0.871948 (rank : 9)	θ value	1.46268e-50 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UWR7, Q96M57	Gene names	ENPP6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP6_MOUSE
NC score	0.869544 (rank : 10)	θ value	4.70527e-49 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGN3, Q4VAH5	Gene names	Enpp6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

PP11_HUMAN
NC score	0.310137 (rank : 11)	θ value	0.000270298 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

PRG4_MOUSE
NC score	0.201006 (rank : 12)	θ value	8.11959e-09 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	624	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
NC score	0.179535 (rank : 13)	θ value	3.08544e-08 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	764	Shared Neighborhood Hits	13
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PIGO_HUMAN
NC score	0.159645 (rank : 14)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TEQ8, Q6P154, Q6UX80, Q8TDS8, Q96CS9, Q9BVN9, Q9Y4B0	Gene names	PIGO
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

PIGG_HUMAN
NC score	0.159566 (rank : 15)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

VTNC_MOUSE
NC score	0.154871 (rank : 16)	θ value	0.00869519 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

PIGO_MOUSE
NC score	0.152679 (rank : 17)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JJI6, Q9CRY2	Gene names	Pigo
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

VTNC_HUMAN
NC score	0.146320 (rank : 18)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

SUSD2_HUMAN
NC score	0.107802 (rank : 19)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

PIGN_MOUSE
NC score	0.100305 (rank : 20)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

PIGN_HUMAN
NC score	0.091681 (rank : 21)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O95427, Q7L8F8, Q8TC01, Q9NT05	Gene names	PIGN, MCD4
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) (MCD4 homolog).

SUSD2_MOUSE
NC score	0.090766 (rank : 22)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	104	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TINAG_HUMAN
NC score	0.086801 (rank : 23)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

NUCGL_HUMAN
NC score	0.064605 (rank : 24)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2C4	Gene names	ENDOGL1, ENGL
Domain Architecture
Description	Endonuclease G-like 1 (EC 3.1.30.-) (Endo G-like).

CECR1_HUMAN
NC score	0.053067 (rank : 25)	θ value	0.125558 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZK5, Q96K41	Gene names	CECR1
Domain Architecture
Description	Cat eye syndrome critical region protein 1 precursor.

KRA59_HUMAN
NC score	0.050219 (rank : 26)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA54_HUMAN
NC score	0.035641 (rank : 27)	θ value	0.0736092 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	270	Shared Neighborhood Hits	14
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA58_HUMAN
NC score	0.035212 (rank : 28)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	324	Shared Neighborhood Hits	17
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA94_HUMAN
NC score	0.029742 (rank : 29)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

ARSA_HUMAN
NC score	0.028839 (rank : 30)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	P15289, Q6ICI5, Q96CJ0	Gene names	ARSA
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C].

KRA47_HUMAN
NC score	0.026446 (rank : 31)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

ERGI1_HUMAN
NC score	0.025954 (rank : 32)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q969X5, Q9H0L0, Q9H2J2, Q9ULN9	Gene names	ERGIC1, ERGIC32, KIAA1181
Domain Architecture	No domain graphic available
Description	Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER- Golgi intermediate compartment 32 kDa protein) (ERGIC-32).

ERGI1_MOUSE
NC score	0.025930 (rank : 33)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DC16	Gene names	Ergic1, Ergic32
Domain Architecture	No domain graphic available
Description	Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER- Golgi intermediate compartment 32 kDa protein) (ERGIC-32).

KRA57_HUMAN
NC score	0.025738 (rank : 34)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NUCG_MOUSE
NC score	0.025124 (rank : 35)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	O08600	Gene names	Endog
Domain Architecture
Description	Endonuclease G, mitochondrial precursor (EC 3.1.30.-) (Endo G).

TENR_HUMAN
NC score	0.024852 (rank : 36)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	526	Shared Neighborhood Hits	25
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

KRA93_HUMAN
NC score	0.024569 (rank : 37)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA53_HUMAN
NC score	0.024344 (rank : 38)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	331	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

NUCG_HUMAN
NC score	0.023741 (rank : 39)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q14249, Q9BSP2	Gene names	ENDOG
Domain Architecture
Description	Endonuclease G, mitochondrial precursor (EC 3.1.30.-) (Endo G).

TENR_MOUSE
NC score	0.023532 (rank : 40)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	531	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

KR10A_HUMAN
NC score	0.022785 (rank : 41)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	232	Shared Neighborhood Hits	20
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

TENA_HUMAN
NC score	0.021154 (rank : 42)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	631	Shared Neighborhood Hits	30
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

SACS_MOUSE
NC score	0.020951 (rank : 43)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

KR107_HUMAN
NC score	0.019903 (rank : 44)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	330	Shared Neighborhood Hits	22
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

ARSF_HUMAN
NC score	0.018391 (rank : 45)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	P54793, Q8TCC5	Gene names	ARSF
Domain Architecture
Description	Arylsulfatase F precursor (EC 3.1.6.-) (ASF).

KRA98_HUMAN
NC score	0.018128 (rank : 46)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

STS_MOUSE
NC score	0.017278 (rank : 47)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	P50427	Gene names	Sts
Domain Architecture
Description	Steryl-sulfatase precursor (EC 3.1.6.2) (Steroid sulfatase) (Steryl- sulfate sulfohydrolase) (Arylsulfatase C) (ASC).

KR510_HUMAN
NC score	0.016331 (rank : 48)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR104_HUMAN
NC score	0.015245 (rank : 49)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	313	Shared Neighborhood Hits	16
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

SSPO_MOUSE
NC score	0.011804 (rank : 50)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	800	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

LRP4_MOUSE
NC score	0.010732 (rank : 51)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	351	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

JAG1_MOUSE
NC score	0.010620 (rank : 52)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	518	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

LRP4_HUMAN
NC score	0.010420 (rank : 53)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	355	Shared Neighborhood Hits	17
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

NTNG2_HUMAN
NC score	0.007762 (rank : 54)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	276	Shared Neighborhood Hits	11
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

FBLN3_HUMAN
NC score	0.006828 (rank : 55)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	293	Shared Neighborhood Hits	12
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

VEGFD_MOUSE
NC score	0.006805 (rank : 56)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P97946	Gene names	Figf, Vegfd
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

CUBN_MOUSE
NC score	0.006634 (rank : 57)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	477	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBLN3_MOUSE
NC score	0.006612 (rank : 58)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

TSP2_MOUSE
NC score	0.006090 (rank : 59)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	352	Shared Neighborhood Hits	20
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

DSRAD_MOUSE
NC score	0.006042 (rank : 60)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

GP153_MOUSE
NC score	0.005343 (rank : 61)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0Z9, Q80T37, Q8CFK0	Gene names	Gpr153, Pgr1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

ADAM9_MOUSE
NC score	0.005324 (rank : 62)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	325	Shared Neighborhood Hits	21
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADAM9_HUMAN
NC score	0.005216 (rank : 63)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	243	Shared Neighborhood Hits	18
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

EMR2_HUMAN
NC score	0.004403 (rank : 64)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	345	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ST1C2_MOUSE
NC score	0.003241 (rank : 65)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D939, Q3UNA9, Q8R210	Gene names	Sult1c2, Sult1c1
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-).