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Network neighborhood for query Sequence : ENPP3_HUMAN

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ENPP3_HUMAN
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ENPP1_HUMAN
θ value	0 (rank : 1)	NC score	0.989046 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_MOUSE
θ value	0 (rank : 2)	NC score	0.988548 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	65	Shared Neighborhood Hits	22
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
θ value	0 (rank : 3)	NC score	0.978302 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_MOUSE
θ value	0 (rank : 4)	NC score	0.977117 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	66	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP5_MOUSE
θ value	1.04338e-64 (rank : 6)	NC score	0.897369 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EQG7, Q921P7	Gene names	Enpp5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP5_HUMAN
θ value	1.96772e-63 (rank : 7)	NC score	0.897903 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJA9, Q6UX49	Gene names	ENPP5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP6_HUMAN
θ value	3.04986e-48 (rank : 8)	NC score	0.875867 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UWR7, Q96M57	Gene names	ENPP6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP6_MOUSE
θ value	3.04986e-48 (rank : 9)	NC score	0.873390 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGN3, Q4VAH5	Gene names	Enpp6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP7_HUMAN
θ value	3.37202e-47 (rank : 10)	NC score	0.891783 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

PRG4_MOUSE
θ value	1.53129e-07 (rank : 11)	NC score	0.190358 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	624	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
θ value	1.29631e-06 (rank : 12)	NC score	0.169751 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	764	Shared Neighborhood Hits	15
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TINAG_HUMAN
θ value	0.00134147 (rank : 13)	NC score	0.094474 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

PP11_HUMAN
θ value	0.00509761 (rank : 14)	NC score	0.291222 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

SUSD2_MOUSE
θ value	0.0736092 (rank : 15)	NC score	0.088094 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

PIGG_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.138166 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

VTNC_MOUSE
θ value	0.47712 (rank : 17)	NC score	0.134652 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

SUSD2_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.101857 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

LRP1B_MOUSE
θ value	1.06291 (rank : 19)	NC score	0.011498 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	606	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

RPGR1_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.013148 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	578	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

KRA54_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.029770 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	270	Shared Neighborhood Hits	8
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

FBLN2_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.010289 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	392	Shared Neighborhood Hits	10
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

VTNC_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.125055 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

ENDD1_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.016027 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C522, Q4VA96, Q8C5M1, Q8VE35	Gene names	Endod1, Kiaa0830
Domain Architecture	No domain graphic available
Description	Endonuclease domain-containing 1 protein precursor (EC 3.1.30.-).

FBLN2_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.009201 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	505	Shared Neighborhood Hits	10
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

NELL2_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.007831 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	449	Shared Neighborhood Hits	10
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

PCSK5_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.007086 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	613	Shared Neighborhood Hits	10
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ITA9_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.004050 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q13797, Q14638	Gene names	ITGA9
Domain Architecture
Description	Integrin alpha-9 precursor (Integrin alpha-RLC).

PIGN_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.062484 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O95427, Q7L8F8, Q8TC01, Q9NT05	Gene names	PIGN, MCD4
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) (MCD4 homolog).

SLIT1_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.002610 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	715	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ITB6_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.005210 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	341	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

NOTC2_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.005935 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	1069	Shared Neighborhood Hits	13
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PIGN_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.070700 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

ZN639_HUMAN
θ value	8.99809 (rank : 34)	NC score	-0.001353 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	723	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UID6	Gene names	ZNF639, ZASC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 639 (Zinc finger protein ZASC1) (Zinc finger protein ANC_2H01).

PIGO_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.123205 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TEQ8, Q6P154, Q6UX80, Q8TDS8, Q96CS9, Q9BVN9, Q9Y4B0	Gene names	PIGO
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

PIGO_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.116866 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JJI6, Q9CRY2	Gene names	Pigo
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

Hits sorted by NC score

ENPP3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_HUMAN
NC score	0.989046 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP1_MOUSE
NC score	0.988548 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	65	Shared Neighborhood Hits	22
SwissProt Accessions	P06802	Gene names	Enpp1, Npps, Pc1, Pdnp1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Antigen Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
NC score	0.978302 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_MOUSE
NC score	0.977117 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	66	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP5_HUMAN
NC score	0.897903 (rank : 6)	θ value	1.96772e-63 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJA9, Q6UX49	Gene names	ENPP5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP5_MOUSE
NC score	0.897369 (rank : 7)	θ value	1.04338e-64 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EQG7, Q921P7	Gene names	Enpp5
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 5 precursor (EC 3.1.-.-) (E-NPP5) (NPP-5).

ENPP7_HUMAN
NC score	0.891783 (rank : 8)	θ value	3.37202e-47 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UWV6, Q6ZTS5, Q8IUS8	Gene names	ENPP7
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 7 precursor (EC 3.1.4.12) (E-NPP7) (NPP-7) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase).

ENPP6_HUMAN
NC score	0.875867 (rank : 9)	θ value	3.04986e-48 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UWR7, Q96M57	Gene names	ENPP6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

ENPP6_MOUSE
NC score	0.873390 (rank : 10)	θ value	3.04986e-48 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGN3, Q4VAH5	Gene names	Enpp6
Domain Architecture	No domain graphic available
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 6 precursor (EC 3.1.-.-) (E-NPP6) (NPP-6) [Contains: Ectonucleotide pyrophosphatase/phosphodiesterase 6 soluble form].

PP11_HUMAN
NC score	0.291222 (rank : 11)	θ value	0.00509761 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

PRG4_MOUSE
NC score	0.190358 (rank : 12)	θ value	1.53129e-07 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	624	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
NC score	0.169751 (rank : 13)	θ value	1.29631e-06 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	764	Shared Neighborhood Hits	15
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PIGG_HUMAN
NC score	0.138166 (rank : 14)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

VTNC_MOUSE
NC score	0.134652 (rank : 15)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

VTNC_HUMAN
NC score	0.125055 (rank : 16)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

PIGO_HUMAN
NC score	0.123205 (rank : 17)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TEQ8, Q6P154, Q6UX80, Q8TDS8, Q96CS9, Q9BVN9, Q9Y4B0	Gene names	PIGO
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

PIGO_MOUSE
NC score	0.116866 (rank : 18)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JJI6, Q9CRY2	Gene names	Pigo
Domain Architecture
Description	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O).

SUSD2_HUMAN
NC score	0.101857 (rank : 19)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TINAG_HUMAN
NC score	0.094474 (rank : 20)	θ value	0.00134147 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

SUSD2_MOUSE
NC score	0.088094 (rank : 21)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

PIGN_MOUSE
NC score	0.070700 (rank : 22)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

PIGN_HUMAN
NC score	0.062484 (rank : 23)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O95427, Q7L8F8, Q8TC01, Q9NT05	Gene names	PIGN, MCD4
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) (MCD4 homolog).

KRA54_HUMAN
NC score	0.029770 (rank : 24)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	270	Shared Neighborhood Hits	8
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

ENDD1_MOUSE
NC score	0.016027 (rank : 25)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C522, Q4VA96, Q8C5M1, Q8VE35	Gene names	Endod1, Kiaa0830
Domain Architecture	No domain graphic available
Description	Endonuclease domain-containing 1 protein precursor (EC 3.1.30.-).

RPGR1_HUMAN
NC score	0.013148 (rank : 26)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	578	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

LRP1B_MOUSE
NC score	0.011498 (rank : 27)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	606	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN2_HUMAN
NC score	0.010289 (rank : 28)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	392	Shared Neighborhood Hits	10
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
NC score	0.009201 (rank : 29)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	505	Shared Neighborhood Hits	10
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

NELL2_HUMAN
NC score	0.007831 (rank : 30)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	449	Shared Neighborhood Hits	10
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

PCSK5_MOUSE
NC score	0.007086 (rank : 31)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	613	Shared Neighborhood Hits	10
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

NOTC2_MOUSE
NC score	0.005935 (rank : 32)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	1069	Shared Neighborhood Hits	13
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ITB6_MOUSE
NC score	0.005210 (rank : 33)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	341	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITA9_HUMAN
NC score	0.004050 (rank : 34)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q13797, Q14638	Gene names	ITGA9
Domain Architecture
Description	Integrin alpha-9 precursor (Integrin alpha-RLC).

SLIT1_MOUSE
NC score	0.002610 (rank : 35)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	715	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ZN639_HUMAN
NC score	-0.001353 (rank : 36)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	723	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UID6	Gene names	ZNF639, ZASC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 639 (Zinc finger protein ZASC1) (Zinc finger protein ANC_2H01).