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Network neighborhood for query Sequence : AXN2_HUMAN

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AXN2_HUMAN
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AXN2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN2_MOUSE
θ value	0 (rank : 2)	NC score	0.989516 (rank : 2)
Query Neighborhood Hits	102	Target Neighborhood Hits	116	Shared Neighborhood Hits	63
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN1_MOUSE
θ value	6.38546e-147 (rank : 3)	NC score	0.954450 (rank : 3)
Query Neighborhood Hits	102	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AXN1_HUMAN
θ value	8.33966e-147 (rank : 4)	NC score	0.953621 (rank : 4)
Query Neighborhood Hits	102	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

RGS18_HUMAN
θ value	1.52774e-15 (rank : 5)	NC score	0.687936 (rank : 6)
Query Neighborhood Hits	102	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS18_MOUSE
θ value	1.68911e-14 (rank : 6)	NC score	0.686424 (rank : 7)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS3_HUMAN
θ value	2.43908e-13 (rank : 7)	NC score	0.491598 (rank : 37)
Query Neighborhood Hits	102	Target Neighborhood Hits	1375	Shared Neighborhood Hits	57
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	6.00763e-12 (rank : 8)	NC score	0.435760 (rank : 40)
Query Neighborhood Hits	102	Target Neighborhood Hits	1621	Shared Neighborhood Hits	60
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RGS10_HUMAN
θ value	1.02475e-11 (rank : 9)	NC score	0.691038 (rank : 5)
Query Neighborhood Hits	102	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS2_HUMAN
θ value	1.02475e-11 (rank : 10)	NC score	0.671314 (rank : 9)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	44
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS1_MOUSE
θ value	3.89403e-11 (rank : 11)	NC score	0.667241 (rank : 14)
Query Neighborhood Hits	102	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS2_MOUSE
θ value	3.89403e-11 (rank : 12)	NC score	0.667182 (rank : 15)
Query Neighborhood Hits	102	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS1_HUMAN
θ value	5.08577e-11 (rank : 13)	NC score	0.670805 (rank : 10)
Query Neighborhood Hits	102	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS10_MOUSE
θ value	6.64225e-11 (rank : 14)	NC score	0.683127 (rank : 8)
Query Neighborhood Hits	102	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS8_MOUSE
θ value	6.64225e-11 (rank : 15)	NC score	0.668310 (rank : 12)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS8_HUMAN
θ value	8.67504e-11 (rank : 16)	NC score	0.667487 (rank : 13)
Query Neighborhood Hits	102	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS4_HUMAN
θ value	2.52405e-10 (rank : 17)	NC score	0.663090 (rank : 16)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS5_HUMAN
θ value	7.34386e-10 (rank : 18)	NC score	0.669426 (rank : 11)
Query Neighborhood Hits	102	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS4_MOUSE
θ value	1.25267e-09 (rank : 19)	NC score	0.662454 (rank : 18)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS14_MOUSE
θ value	2.79066e-09 (rank : 20)	NC score	0.618771 (rank : 29)
Query Neighborhood Hits	102	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS5_MOUSE
θ value	4.76016e-09 (rank : 21)	NC score	0.662722 (rank : 17)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS13_HUMAN
θ value	8.11959e-09 (rank : 22)	NC score	0.655451 (rank : 20)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS14_HUMAN
θ value	1.38499e-08 (rank : 23)	NC score	0.608491 (rank : 30)
Query Neighborhood Hits	102	Target Neighborhood Hits	77	Shared Neighborhood Hits	42
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS16_HUMAN
θ value	1.38499e-08 (rank : 24)	NC score	0.651537 (rank : 22)
Query Neighborhood Hits	102	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS19_MOUSE
θ value	1.38499e-08 (rank : 25)	NC score	0.634855 (rank : 24)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS16_MOUSE
θ value	3.08544e-08 (rank : 26)	NC score	0.654085 (rank : 21)
Query Neighborhood Hits	102	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS20_MOUSE
θ value	3.08544e-08 (rank : 27)	NC score	0.633363 (rank : 25)
Query Neighborhood Hits	102	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS13_MOUSE
θ value	8.97725e-08 (rank : 28)	NC score	0.656305 (rank : 19)
Query Neighborhood Hits	102	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS17_MOUSE
θ value	1.17247e-07 (rank : 29)	NC score	0.636013 (rank : 23)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS19_HUMAN
θ value	1.17247e-07 (rank : 30)	NC score	0.632871 (rank : 26)
Query Neighborhood Hits	102	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS17_HUMAN
θ value	1.99992e-07 (rank : 31)	NC score	0.627288 (rank : 27)
Query Neighborhood Hits	102	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS20_HUMAN
θ value	9.92553e-07 (rank : 32)	NC score	0.620860 (rank : 28)
Query Neighborhood Hits	102	Target Neighborhood Hits	55	Shared Neighborhood Hits	43
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS11_HUMAN
θ value	1.69304e-06 (rank : 33)	NC score	0.557248 (rank : 31)
Query Neighborhood Hits	102	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS12_HUMAN
θ value	1.43324e-05 (rank : 34)	NC score	0.513123 (rank : 34)
Query Neighborhood Hits	102	Target Neighborhood Hits	333	Shared Neighborhood Hits	51
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS9_HUMAN
θ value	1.43324e-05 (rank : 35)	NC score	0.536527 (rank : 33)
Query Neighborhood Hits	102	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_MOUSE
θ value	1.43324e-05 (rank : 36)	NC score	0.537105 (rank : 32)
Query Neighborhood Hits	102	Target Neighborhood Hits	65	Shared Neighborhood Hits	47
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

DVL2_HUMAN
θ value	1.87187e-05 (rank : 37)	NC score	0.238175 (rank : 43)
Query Neighborhood Hits	102	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	1.87187e-05 (rank : 38)	NC score	0.237756 (rank : 44)
Query Neighborhood Hits	102	Target Neighborhood Hits	233	Shared Neighborhood Hits	21
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	1.87187e-05 (rank : 39)	NC score	0.245908 (rank : 42)
Query Neighborhood Hits	102	Target Neighborhood Hits	194	Shared Neighborhood Hits	21
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	1.87187e-05 (rank : 40)	NC score	0.246209 (rank : 41)
Query Neighborhood Hits	102	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1L_HUMAN
θ value	0.000602161 (rank : 41)	NC score	0.220924 (rank : 45)
Query Neighborhood Hits	102	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_MOUSE
θ value	0.000602161 (rank : 42)	NC score	0.218633 (rank : 46)
Query Neighborhood Hits	102	Target Neighborhood Hits	146	Shared Neighborhood Hits	18
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_HUMAN
θ value	0.000786445 (rank : 43)	NC score	0.218090 (rank : 47)
Query Neighborhood Hits	102	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

RGS6_MOUSE
θ value	0.00102713 (rank : 44)	NC score	0.491172 (rank : 38)
Query Neighborhood Hits	102	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS7_HUMAN
θ value	0.00134147 (rank : 45)	NC score	0.504767 (rank : 35)
Query Neighborhood Hits	102	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_MOUSE
θ value	0.00298849 (rank : 46)	NC score	0.497885 (rank : 36)
Query Neighborhood Hits	102	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

LMBTL_HUMAN
θ value	0.0148317 (rank : 47)	NC score	0.038704 (rank : 59)
Query Neighborhood Hits	102	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y468, Q5H8Y8, Q8IUV7, Q9H1E6, Q9H1G5, Q9UG06, Q9UJB9, Q9Y4C9	Gene names	L3MBTL, KIAA0681, L3MBT
Domain Architecture
Description	Lethal(3)malignant brain tumor-like protein (L(3)mbt-like) (L(3)mbt protein homolog) (H-l(3)mbt protein) (H-L(3)MBT) (L3MBTL1).

RGS6_HUMAN
θ value	0.0193708 (rank : 48)	NC score	0.462805 (rank : 39)
Query Neighborhood Hits	102	Target Neighborhood Hits	80	Shared Neighborhood Hits	40
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

TARA_MOUSE
θ value	0.0563607 (rank : 49)	NC score	0.029760 (rank : 63)
Query Neighborhood Hits	102	Target Neighborhood Hits	1133	Shared Neighborhood Hits	18
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

AHTF1_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.048295 (rank : 56)
Query Neighborhood Hits	102	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

AAKG2_MOUSE
θ value	0.21417 (rank : 51)	NC score	0.025753 (rank : 67)
Query Neighborhood Hits	102	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

MKL1_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.048311 (rank : 55)
Query Neighborhood Hits	102	Target Neighborhood Hits	232	Shared Neighborhood Hits	8
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MKL1_MOUSE
θ value	0.279714 (rank : 53)	NC score	0.040401 (rank : 57)
Query Neighborhood Hits	102	Target Neighborhood Hits	667	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NFH_HUMAN
θ value	0.279714 (rank : 54)	NC score	0.014572 (rank : 77)
Query Neighborhood Hits	102	Target Neighborhood Hits	1242	Shared Neighborhood Hits	15
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TEAD2_HUMAN
θ value	0.279714 (rank : 55)	NC score	0.028122 (rank : 65)
Query Neighborhood Hits	102	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q15562, Q96IG3	Gene names	TEAD2, TEF4
Domain Architecture
Description	Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2).

PO6F2_MOUSE
θ value	0.365318 (rank : 56)	NC score	0.039045 (rank : 58)
Query Neighborhood Hits	102	Target Neighborhood Hits	639	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

JIP3_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.024797 (rank : 68)
Query Neighborhood Hits	102	Target Neighborhood Hits	1039	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

ULK2_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.001738 (rank : 104)
Query Neighborhood Hits	102	Target Neighborhood Hits	979	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

WHRN_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.030960 (rank : 62)
Query Neighborhood Hits	102	Target Neighborhood Hits	325	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

KIF1A_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.010556 (rank : 82)
Query Neighborhood Hits	102	Target Neighborhood Hits	240	Shared Neighborhood Hits	3
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1A_MOUSE
θ value	1.38821 (rank : 61)	NC score	0.012004 (rank : 81)
Query Neighborhood Hits	102	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

PMS2_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.020073 (rank : 71)
Query Neighborhood Hits	102	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PARD3_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.038212 (rank : 60)
Query Neighborhood Hits	102	Target Neighborhood Hits	290	Shared Neighborhood Hits	12
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

TEAD2_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.022375 (rank : 69)
Query Neighborhood Hits	102	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P48301, Q62297	Gene names	Tead2, Etdf, Etf, Tef4
Domain Architecture
Description	Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2) (Embryonic TEA domain-containing factor) (ETF) (ETEF-1).

IWS1_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.014419 (rank : 78)
Query Neighborhood Hits	102	Target Neighborhood Hits	1241	Shared Neighborhood Hits	12
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PUNC_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.006431 (rank : 92)
Query Neighborhood Hits	102	Target Neighborhood Hits	449	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

SEN2_MOUSE
θ value	2.36792 (rank : 67)	NC score	0.021801 (rank : 70)
Query Neighborhood Hits	102	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

AKA10_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.195746 (rank : 48)
Query Neighborhood Hits	102	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.195307 (rank : 49)
Query Neighborhood Hits	102	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

CAC1B_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.007557 (rank : 90)
Query Neighborhood Hits	102	Target Neighborhood Hits	257	Shared Neighborhood Hits	8
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CV106_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.036429 (rank : 61)
Query Neighborhood Hits	102	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

MYPC2_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.008654 (rank : 87)
Query Neighborhood Hits	102	Target Neighborhood Hits	316	Shared Neighborhood Hits	5
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

SCG2_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.029678 (rank : 64)
Query Neighborhood Hits	102	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

SNX14_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.089893 (rank : 52)
Query Neighborhood Hits	102	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.088460 (rank : 53)
Query Neighborhood Hits	102	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

5NT1B_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.017998 (rank : 73)
Query Neighborhood Hits	102	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

FBX41_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.012606 (rank : 80)
Query Neighborhood Hits	102	Target Neighborhood Hits	475	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

CT112_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.026017 (rank : 66)
Query Neighborhood Hits	102	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

FILA_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.018262 (rank : 72)
Query Neighborhood Hits	102	Target Neighborhood Hits	685	Shared Neighborhood Hits	13
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GASP1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.009947 (rank : 83)
Query Neighborhood Hits	102	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

GCC1_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.005165 (rank : 99)
Query Neighborhood Hits	102	Target Neighborhood Hits	887	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.006195 (rank : 93)
Query Neighborhood Hits	102	Target Neighborhood Hits	777	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

IASPP_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.008213 (rank : 88)
Query Neighborhood Hits	102	Target Neighborhood Hits	1024	Shared Neighborhood Hits	14
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ITPR3_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.008970 (rank : 86)
Query Neighborhood Hits	102	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

MYPC2_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.007879 (rank : 89)
Query Neighborhood Hits	102	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

SC11A_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.005212 (rank : 98)
Query Neighborhood Hits	102	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

ULK2_MOUSE
θ value	5.27518 (rank : 87)	NC score	-0.000502 (rank : 105)
Query Neighborhood Hits	102	Target Neighborhood Hits	943	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

ACF_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.004923 (rank : 101)
Query Neighborhood Hits	102	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q5YD48, Q5FW55, Q5YD47	Gene names	Acf, Asp
Domain Architecture	No domain graphic available
Description	APOBEC1 complementation factor (APOBEC1-stimulating protein).

BAT3_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.016900 (rank : 75)
Query Neighborhood Hits	102	Target Neighborhood Hits	518	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

ICOSL_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.009664 (rank : 84)
Query Neighborhood Hits	102	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

KBTB3_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.001942 (rank : 103)
Query Neighborhood Hits	102	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHI4, Q8BNJ8	Gene names	Kbtbd3, Bklhd3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

PAX1_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.005405 (rank : 97)
Query Neighborhood Hits	102	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

PHLPP_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.006129 (rank : 95)
Query Neighborhood Hits	102	Target Neighborhood Hits	604	Shared Neighborhood Hits	11
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

ZCHC6_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.009043 (rank : 85)
Query Neighborhood Hits	102	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

AN13D_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.005425 (rank : 96)
Query Neighborhood Hits	102	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

CNTP2_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.002315 (rank : 102)
Query Neighborhood Hits	102	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

GPC2_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.005056 (rank : 100)
Query Neighborhood Hits	102	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BKV1	Gene names	Gpc2
Domain Architecture	No domain graphic available
Description	Glypican-2 precursor.

NACAM_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.012801 (rank : 79)
Query Neighborhood Hits	102	Target Neighborhood Hits	1866	Shared Neighborhood Hits	20
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TIF1G_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.006146 (rank : 94)
Query Neighborhood Hits	102	Target Neighborhood Hits	410	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRRAP_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.016902 (rank : 74)
Query Neighborhood Hits	102	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

TRRAP_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.014825 (rank : 76)
Query Neighborhood Hits	102	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

WDR4_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.007443 (rank : 91)
Query Neighborhood Hits	102	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EP82	Gene names	Wdr4
Domain Architecture
Description	WD repeat protein 4.

SNX13_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.165306 (rank : 51)
Query Neighborhood Hits	102	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX13_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.167430 (rank : 50)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNX25_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.075652 (rank : 54)
Query Neighborhood Hits	102	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

Hits sorted by NC score

AXN2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN2_MOUSE
NC score	0.989516 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	102	Target Neighborhood Hits	116	Shared Neighborhood Hits	63
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN1_MOUSE
NC score	0.954450 (rank : 3)	θ value	6.38546e-147 (rank : 3)
Query Neighborhood Hits	102	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AXN1_HUMAN
NC score	0.953621 (rank : 4)	θ value	8.33966e-147 (rank : 4)
Query Neighborhood Hits	102	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

RGS10_HUMAN
NC score	0.691038 (rank : 5)	θ value	1.02475e-11 (rank : 9)
Query Neighborhood Hits	102	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS18_HUMAN
NC score	0.687936 (rank : 6)	θ value	1.52774e-15 (rank : 5)
Query Neighborhood Hits	102	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS18_MOUSE
NC score	0.686424 (rank : 7)	θ value	1.68911e-14 (rank : 6)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS10_MOUSE
NC score	0.683127 (rank : 8)	θ value	6.64225e-11 (rank : 14)
Query Neighborhood Hits	102	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS2_HUMAN
NC score	0.671314 (rank : 9)	θ value	1.02475e-11 (rank : 10)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	44
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS1_HUMAN
NC score	0.670805 (rank : 10)	θ value	5.08577e-11 (rank : 13)
Query Neighborhood Hits	102	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS5_HUMAN
NC score	0.669426 (rank : 11)	θ value	7.34386e-10 (rank : 18)
Query Neighborhood Hits	102	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS8_MOUSE
NC score	0.668310 (rank : 12)	θ value	6.64225e-11 (rank : 15)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS8_HUMAN
NC score	0.667487 (rank : 13)	θ value	8.67504e-11 (rank : 16)
Query Neighborhood Hits	102	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS1_MOUSE
NC score	0.667241 (rank : 14)	θ value	3.89403e-11 (rank : 11)
Query Neighborhood Hits	102	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS2_MOUSE
NC score	0.667182 (rank : 15)	θ value	3.89403e-11 (rank : 12)
Query Neighborhood Hits	102	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS4_HUMAN
NC score	0.663090 (rank : 16)	θ value	2.52405e-10 (rank : 17)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS5_MOUSE
NC score	0.662722 (rank : 17)	θ value	4.76016e-09 (rank : 21)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS4_MOUSE
NC score	0.662454 (rank : 18)	θ value	1.25267e-09 (rank : 19)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS13_MOUSE
NC score	0.656305 (rank : 19)	θ value	8.97725e-08 (rank : 28)
Query Neighborhood Hits	102	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS13_HUMAN
NC score	0.655451 (rank : 20)	θ value	8.11959e-09 (rank : 22)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS16_MOUSE
NC score	0.654085 (rank : 21)	θ value	3.08544e-08 (rank : 26)
Query Neighborhood Hits	102	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS16_HUMAN
NC score	0.651537 (rank : 22)	θ value	1.38499e-08 (rank : 24)
Query Neighborhood Hits	102	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS17_MOUSE
NC score	0.636013 (rank : 23)	θ value	1.17247e-07 (rank : 29)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS19_MOUSE
NC score	0.634855 (rank : 24)	θ value	1.38499e-08 (rank : 25)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS20_MOUSE
NC score	0.633363 (rank : 25)	θ value	3.08544e-08 (rank : 27)
Query Neighborhood Hits	102	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS19_HUMAN
NC score	0.632871 (rank : 26)	θ value	1.17247e-07 (rank : 30)
Query Neighborhood Hits	102	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS17_HUMAN
NC score	0.627288 (rank : 27)	θ value	1.99992e-07 (rank : 31)
Query Neighborhood Hits	102	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS20_HUMAN
NC score	0.620860 (rank : 28)	θ value	9.92553e-07 (rank : 32)
Query Neighborhood Hits	102	Target Neighborhood Hits	55	Shared Neighborhood Hits	43
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS14_MOUSE
NC score	0.618771 (rank : 29)	θ value	2.79066e-09 (rank : 20)
Query Neighborhood Hits	102	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS14_HUMAN
NC score	0.608491 (rank : 30)	θ value	1.38499e-08 (rank : 23)
Query Neighborhood Hits	102	Target Neighborhood Hits	77	Shared Neighborhood Hits	42
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS11_HUMAN
NC score	0.557248 (rank : 31)	θ value	1.69304e-06 (rank : 33)
Query Neighborhood Hits	102	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS9_MOUSE
NC score	0.537105 (rank : 32)	θ value	1.43324e-05 (rank : 36)
Query Neighborhood Hits	102	Target Neighborhood Hits	65	Shared Neighborhood Hits	47
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_HUMAN
NC score	0.536527 (rank : 33)	θ value	1.43324e-05 (rank : 35)
Query Neighborhood Hits	102	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS12_HUMAN
NC score	0.513123 (rank : 34)	θ value	1.43324e-05 (rank : 34)
Query Neighborhood Hits	102	Target Neighborhood Hits	333	Shared Neighborhood Hits	51
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS7_HUMAN
NC score	0.504767 (rank : 35)	θ value	0.00134147 (rank : 45)
Query Neighborhood Hits	102	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_MOUSE
NC score	0.497885 (rank : 36)	θ value	0.00298849 (rank : 46)
Query Neighborhood Hits	102	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS3_HUMAN
NC score	0.491598 (rank : 37)	θ value	2.43908e-13 (rank : 7)
Query Neighborhood Hits	102	Target Neighborhood Hits	1375	Shared Neighborhood Hits	57
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS6_MOUSE
NC score	0.491172 (rank : 38)	θ value	0.00102713 (rank : 44)
Query Neighborhood Hits	102	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS6_HUMAN
NC score	0.462805 (rank : 39)	θ value	0.0193708 (rank : 48)
Query Neighborhood Hits	102	Target Neighborhood Hits	80	Shared Neighborhood Hits	40
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

RGS3_MOUSE
NC score	0.435760 (rank : 40)	θ value	6.00763e-12 (rank : 8)
Query Neighborhood Hits	102	Target Neighborhood Hits	1621	Shared Neighborhood Hits	60
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DVL3_MOUSE
NC score	0.246209 (rank : 41)	θ value	1.87187e-05 (rank : 40)
Query Neighborhood Hits	102	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_HUMAN
NC score	0.245908 (rank : 42)	θ value	1.87187e-05 (rank : 39)
Query Neighborhood Hits	102	Target Neighborhood Hits	194	Shared Neighborhood Hits	21
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL2_HUMAN
NC score	0.238175 (rank : 43)	θ value	1.87187e-05 (rank : 37)
Query Neighborhood Hits	102	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.237756 (rank : 44)	θ value	1.87187e-05 (rank : 38)
Query Neighborhood Hits	102	Target Neighborhood Hits	233	Shared Neighborhood Hits	21
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL1L_HUMAN
NC score	0.220924 (rank : 45)	θ value	0.000602161 (rank : 41)
Query Neighborhood Hits	102	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_MOUSE
NC score	0.218633 (rank : 46)	θ value	0.000602161 (rank : 42)
Query Neighborhood Hits	102	Target Neighborhood Hits	146	Shared Neighborhood Hits	18
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_HUMAN
NC score	0.218090 (rank : 47)	θ value	0.000786445 (rank : 43)
Query Neighborhood Hits	102	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

AKA10_HUMAN
NC score	0.195746 (rank : 48)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	102	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
NC score	0.195307 (rank : 49)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	102	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SNX13_MOUSE
NC score	0.167430 (rank : 50)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNX13_HUMAN
NC score	0.165306 (rank : 51)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	102	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX14_HUMAN
NC score	0.089893 (rank : 52)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	102	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
NC score	0.088460 (rank : 53)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	102	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX25_HUMAN
NC score	0.075652 (rank : 54)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	102	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

MKL1_HUMAN
NC score	0.048311 (rank : 55)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	102	Target Neighborhood Hits	232	Shared Neighborhood Hits	8
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

AHTF1_HUMAN
NC score	0.048295 (rank : 56)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	102	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

MKL1_MOUSE
NC score	0.040401 (rank : 57)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	102	Target Neighborhood Hits	667	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PO6F2_MOUSE
NC score	0.039045 (rank : 58)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	102	Target Neighborhood Hits	639	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

LMBTL_HUMAN
NC score	0.038704 (rank : 59)	θ value	0.0148317 (rank : 47)
Query Neighborhood Hits	102	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y468, Q5H8Y8, Q8IUV7, Q9H1E6, Q9H1G5, Q9UG06, Q9UJB9, Q9Y4C9	Gene names	L3MBTL, KIAA0681, L3MBT
Domain Architecture
Description	Lethal(3)malignant brain tumor-like protein (L(3)mbt-like) (L(3)mbt protein homolog) (H-l(3)mbt protein) (H-L(3)MBT) (L3MBTL1).

PARD3_MOUSE
NC score	0.038212 (rank : 60)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	102	Target Neighborhood Hits	290	Shared Neighborhood Hits	12
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

CV106_HUMAN
NC score	0.036429 (rank : 61)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	102	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

WHRN_HUMAN
NC score	0.030960 (rank : 62)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	102	Target Neighborhood Hits	325	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

TARA_MOUSE
NC score	0.029760 (rank : 63)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	102	Target Neighborhood Hits	1133	Shared Neighborhood Hits	18
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SCG2_HUMAN
NC score	0.029678 (rank : 64)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	102	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

TEAD2_HUMAN
NC score	0.028122 (rank : 65)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	102	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q15562, Q96IG3	Gene names	TEAD2, TEF4
Domain Architecture
Description	Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2).

CT112_HUMAN
NC score	0.026017 (rank : 66)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	102	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

AAKG2_MOUSE
NC score	0.025753 (rank : 67)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	102	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

JIP3_HUMAN
NC score	0.024797 (rank : 68)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	102	Target Neighborhood Hits	1039	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

TEAD2_MOUSE
NC score	0.022375 (rank : 69)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	102	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P48301, Q62297	Gene names	Tead2, Etdf, Etf, Tef4
Domain Architecture
Description	Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2) (Embryonic TEA domain-containing factor) (ETF) (ETEF-1).

SEN2_MOUSE
NC score	0.021801 (rank : 70)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	102	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

PMS2_HUMAN
NC score	0.020073 (rank : 71)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	102	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

FILA_HUMAN
NC score	0.018262 (rank : 72)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	102	Target Neighborhood Hits	685	Shared Neighborhood Hits	13
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

5NT1B_HUMAN
NC score	0.017998 (rank : 73)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	102	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

TRRAP_HUMAN
NC score	0.016902 (rank : 74)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	102	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

BAT3_MOUSE
NC score	0.016900 (rank : 75)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	102	Target Neighborhood Hits	518	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

TRRAP_MOUSE
NC score	0.014825 (rank : 76)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	102	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

NFH_HUMAN
NC score	0.014572 (rank : 77)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	102	Target Neighborhood Hits	1242	Shared Neighborhood Hits	15
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

IWS1_HUMAN
NC score	0.014419 (rank : 78)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	102	Target Neighborhood Hits	1241	Shared Neighborhood Hits	12
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NACAM_MOUSE
NC score	0.012801 (rank : 79)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	102	Target Neighborhood Hits	1866	Shared Neighborhood Hits	20
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

FBX41_HUMAN
NC score	0.012606 (rank : 80)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	102	Target Neighborhood Hits	475	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

KIF1A_MOUSE
NC score	0.012004 (rank : 81)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	102	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1A_HUMAN
NC score	0.010556 (rank : 82)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	102	Target Neighborhood Hits	240	Shared Neighborhood Hits	3
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

GASP1_MOUSE
NC score	0.009947 (rank : 83)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	102	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

ICOSL_MOUSE
NC score	0.009664 (rank : 84)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	102	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

ZCHC6_HUMAN
NC score	0.009043 (rank : 85)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	102	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

ITPR3_MOUSE
NC score	0.008970 (rank : 86)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	102	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

MYPC2_HUMAN
NC score	0.008654 (rank : 87)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	102	Target Neighborhood Hits	316	Shared Neighborhood Hits	5
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

IASPP_MOUSE
NC score	0.008213 (rank : 88)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	102	Target Neighborhood Hits	1024	Shared Neighborhood Hits	14
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MYPC2_MOUSE
NC score	0.007879 (rank : 89)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	102	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

CAC1B_HUMAN
NC score	0.007557 (rank : 90)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	102	Target Neighborhood Hits	257	Shared Neighborhood Hits	8
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

WDR4_MOUSE
NC score	0.007443 (rank : 91)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	102	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EP82	Gene names	Wdr4
Domain Architecture
Description	WD repeat protein 4.

PUNC_HUMAN
NC score	0.006431 (rank : 92)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	102	Target Neighborhood Hits	449	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

GCC1_MOUSE
NC score	0.006195 (rank : 93)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	102	Target Neighborhood Hits	777	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

TIF1G_HUMAN
NC score	0.006146 (rank : 94)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	102	Target Neighborhood Hits	410	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

PHLPP_HUMAN
NC score	0.006129 (rank : 95)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	102	Target Neighborhood Hits	604	Shared Neighborhood Hits	11
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

AN13D_HUMAN
NC score	0.005425 (rank : 96)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	102	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

PAX1_MOUSE
NC score	0.005405 (rank : 97)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	102	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

SC11A_MOUSE
NC score	0.005212 (rank : 98)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	102	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

GCC1_HUMAN
NC score	0.005165 (rank : 99)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	102	Target Neighborhood Hits	887	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GPC2_MOUSE
NC score	0.005056 (rank : 100)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	102	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BKV1	Gene names	Gpc2
Domain Architecture	No domain graphic available
Description	Glypican-2 precursor.

ACF_MOUSE
NC score	0.004923 (rank : 101)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	102	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q5YD48, Q5FW55, Q5YD47	Gene names	Acf, Asp
Domain Architecture	No domain graphic available
Description	APOBEC1 complementation factor (APOBEC1-stimulating protein).

CNTP2_MOUSE
NC score	0.002315 (rank : 102)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	102	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

KBTB3_MOUSE
NC score	0.001942 (rank : 103)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	102	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHI4, Q8BNJ8	Gene names	Kbtbd3, Bklhd3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

ULK2_HUMAN
NC score	0.001738 (rank : 104)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	102	Target Neighborhood Hits	979	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

ULK2_MOUSE
NC score	-0.000502 (rank : 105)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	102	Target Neighborhood Hits	943	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).