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Network neighborhood for query Sequence : RGS14_HUMAN

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RGS14_HUMAN
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RGS14_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS14_MOUSE
θ value	0 (rank : 2)	NC score	0.994594 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS12_HUMAN
θ value	6.27148e-94 (rank : 3)	NC score	0.859969 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	333	Shared Neighborhood Hits	47
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS10_HUMAN
θ value	4.42448e-31 (rank : 4)	NC score	0.923426 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	44
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS10_MOUSE
θ value	5.77852e-31 (rank : 5)	NC score	0.921864 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS11_HUMAN
θ value	5.99374e-20 (rank : 6)	NC score	0.817982 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	68	Shared Neighborhood Hits	42
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS5_MOUSE
θ value	5.99374e-20 (rank : 7)	NC score	0.872379 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	44
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS19_MOUSE
θ value	1.02238e-19 (rank : 8)	NC score	0.868310 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS20_HUMAN
θ value	1.02238e-19 (rank : 9)	NC score	0.863381 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	44
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS20_MOUSE
θ value	1.02238e-19 (rank : 10)	NC score	0.867559 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS9_MOUSE
θ value	2.97466e-19 (rank : 11)	NC score	0.805591 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS19_HUMAN
θ value	3.88503e-19 (rank : 12)	NC score	0.864745 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS9_HUMAN
θ value	5.07402e-19 (rank : 13)	NC score	0.804666 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS4_HUMAN
θ value	8.65492e-19 (rank : 14)	NC score	0.867696 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS18_MOUSE
θ value	1.13037e-18 (rank : 15)	NC score	0.861383 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	43
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS7_MOUSE
θ value	1.47631e-18 (rank : 16)	NC score	0.796584 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	42
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS18_HUMAN
θ value	1.92812e-18 (rank : 17)	NC score	0.862274 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	44	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS4_MOUSE
θ value	1.92812e-18 (rank : 18)	NC score	0.866938 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS6_MOUSE
θ value	1.92812e-18 (rank : 19)	NC score	0.794371 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS5_HUMAN
θ value	3.28887e-18 (rank : 20)	NC score	0.863928 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS16_MOUSE
θ value	9.56915e-18 (rank : 21)	NC score	0.861573 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS7_HUMAN
θ value	9.56915e-18 (rank : 22)	NC score	0.796460 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS16_HUMAN
θ value	1.24977e-17 (rank : 23)	NC score	0.861507 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS17_HUMAN
θ value	2.7842e-17 (rank : 24)	NC score	0.864983 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS2_MOUSE
θ value	3.63628e-17 (rank : 25)	NC score	0.852976 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	43
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS1_MOUSE
θ value	4.74913e-17 (rank : 26)	NC score	0.865943 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS8_HUMAN
θ value	4.74913e-17 (rank : 27)	NC score	0.862253 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS17_MOUSE
θ value	6.20254e-17 (rank : 28)	NC score	0.864865 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS2_HUMAN
θ value	6.20254e-17 (rank : 29)	NC score	0.854140 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS8_MOUSE
θ value	8.10077e-17 (rank : 30)	NC score	0.861405 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS3_HUMAN
θ value	1.38178e-16 (rank : 31)	NC score	0.611447 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	1375	Shared Neighborhood Hits	54
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	1.38178e-16 (rank : 32)	NC score	0.545917 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	1621	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RGS1_HUMAN
θ value	6.85773e-16 (rank : 33)	NC score	0.864532 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS6_HUMAN
θ value	1.16975e-15 (rank : 34)	NC score	0.770881 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	80	Shared Neighborhood Hits	43
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

RGS13_HUMAN
θ value	7.09661e-13 (rank : 35)	NC score	0.851355 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS13_MOUSE
θ value	7.09661e-13 (rank : 36)	NC score	0.851805 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

AXN1_MOUSE
θ value	1.133e-10 (rank : 37)	NC score	0.640013 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AXN1_HUMAN
θ value	7.34386e-10 (rank : 38)	NC score	0.621802 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

AXN2_HUMAN
θ value	1.38499e-08 (rank : 39)	NC score	0.608491 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	102	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN2_MOUSE
θ value	1.53129e-07 (rank : 40)	NC score	0.596286 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AKA10_HUMAN
θ value	7.1131e-05 (rank : 41)	NC score	0.340573 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_MOUSE
θ value	7.1131e-05 (rank : 42)	NC score	0.340628 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

CCD22_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.042290 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

SNX13_MOUSE
θ value	0.0736092 (rank : 44)	NC score	0.278545 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

CTDP1_HUMAN
θ value	0.0961366 (rank : 45)	NC score	0.043365 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	416	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

SNX13_HUMAN
θ value	0.0961366 (rank : 46)	NC score	0.272355 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

CABL2_HUMAN
θ value	0.21417 (rank : 47)	NC score	0.029118 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

LYSM3_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.033087 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LE3	Gene names	Lysmd3
Domain Architecture	No domain graphic available
Description	LysM and putative peptidoglycan-binding domain-containing protein 3.

PTN23_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.016044 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	646	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

ZNT3_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.020795 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99726	Gene names	SLC30A3, ZNT3
Domain Architecture
Description	Zinc transporter 3 (ZnT-3) (Solute carrier family 30 member 3).

PCLO_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.016304 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	2046	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MAST3_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.000544 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	1128	Shared Neighborhood Hits	9
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

SPTA1_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.008121 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	748	Shared Neighborhood Hits	6
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

KCNH2_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.013127 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

RPP25_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.025801 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BUL9, Q9NX88	Gene names	RPP25
Domain Architecture	No domain graphic available
Description	Ribonuclease P protein subunit p25 (EC 3.1.26.5) (RNase P protein subunit p25).

CS029_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.015923 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

KCNH2_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.014110 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

MLL2_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.015385 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	1788	Shared Neighborhood Hits	16
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PCNT_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.006336 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	1207	Shared Neighborhood Hits	12
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

CRCM_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.009188 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	520	Shared Neighborhood Hits	8
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

PELP1_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.023804 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	596	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

KLF4_HUMAN
θ value	4.03905 (rank : 62)	NC score	-0.003312 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	709	Shared Neighborhood Hits	2
SwissProt Accessions	O43474, P78338, Q9UNP3	Gene names	KLF4, EZF, GKLF
Domain Architecture
Description	Krueppel-like factor 4 (Epithelial zinc-finger protein EZF) (Gut- enriched krueppel-like factor).

SPTA1_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.007901 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	675	Shared Neighborhood Hits	8
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ITA2B_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.004457 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QUM0, Q64229, Q9Z2M0	Gene names	Itga2b
Domain Architecture
Description	Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen) [Contains: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain].

JIP2_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.019944 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

RGNEF_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.006962 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	641	Shared Neighborhood Hits	9
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ARHGB_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.034327 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	375	Shared Neighborhood Hits	12
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

KI21A_HUMAN
θ value	6.88961 (rank : 68)	NC score	-0.000478 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	1543	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KI21A_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.000417 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	1317	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MELPH_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.011092 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

MTMR5_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.005013 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

ZFY28_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.006446 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ASPP1_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.007448 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	1244	Shared Neighborhood Hits	12
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

KIF1B_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.002761 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

LY10_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.005285 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

PLVAP_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.006740 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	210	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VC4, Q99JB1	Gene names	Plvap, Pv1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (MECA-32 antigen).

SMRC2_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.011412 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	499	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SNX14_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.052200 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX25_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.124365 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

Hits sorted by NC score

RGS14_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS14_MOUSE
NC score	0.994594 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS10_HUMAN
NC score	0.923426 (rank : 3)	θ value	4.42448e-31 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	44
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS10_MOUSE
NC score	0.921864 (rank : 4)	θ value	5.77852e-31 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS5_MOUSE
NC score	0.872379 (rank : 5)	θ value	5.99374e-20 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	44
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS19_MOUSE
NC score	0.868310 (rank : 6)	θ value	1.02238e-19 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS4_HUMAN
NC score	0.867696 (rank : 7)	θ value	8.65492e-19 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS20_MOUSE
NC score	0.867559 (rank : 8)	θ value	1.02238e-19 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS4_MOUSE
NC score	0.866938 (rank : 9)	θ value	1.92812e-18 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS1_MOUSE
NC score	0.865943 (rank : 10)	θ value	4.74913e-17 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS17_HUMAN
NC score	0.864983 (rank : 11)	θ value	2.7842e-17 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS17_MOUSE
NC score	0.864865 (rank : 12)	θ value	6.20254e-17 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS19_HUMAN
NC score	0.864745 (rank : 13)	θ value	3.88503e-19 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS1_HUMAN
NC score	0.864532 (rank : 14)	θ value	6.85773e-16 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS5_HUMAN
NC score	0.863928 (rank : 15)	θ value	3.28887e-18 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS20_HUMAN
NC score	0.863381 (rank : 16)	θ value	1.02238e-19 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	44
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS18_HUMAN
NC score	0.862274 (rank : 17)	θ value	1.92812e-18 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	44	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS8_HUMAN
NC score	0.862253 (rank : 18)	θ value	4.74913e-17 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS16_MOUSE
NC score	0.861573 (rank : 19)	θ value	9.56915e-18 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS16_HUMAN
NC score	0.861507 (rank : 20)	θ value	1.24977e-17 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS8_MOUSE
NC score	0.861405 (rank : 21)	θ value	8.10077e-17 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS18_MOUSE
NC score	0.861383 (rank : 22)	θ value	1.13037e-18 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	43
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS12_HUMAN
NC score	0.859969 (rank : 23)	θ value	6.27148e-94 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	333	Shared Neighborhood Hits	47
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS2_HUMAN
NC score	0.854140 (rank : 24)	θ value	6.20254e-17 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS2_MOUSE
NC score	0.852976 (rank : 25)	θ value	3.63628e-17 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	43
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS13_MOUSE
NC score	0.851805 (rank : 26)	θ value	7.09661e-13 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS13_HUMAN
NC score	0.851355 (rank : 27)	θ value	7.09661e-13 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS11_HUMAN
NC score	0.817982 (rank : 28)	θ value	5.99374e-20 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	68	Shared Neighborhood Hits	42
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS9_MOUSE
NC score	0.805591 (rank : 29)	θ value	2.97466e-19 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_HUMAN
NC score	0.804666 (rank : 30)	θ value	5.07402e-19 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS7_MOUSE
NC score	0.796584 (rank : 31)	θ value	1.47631e-18 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	42
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_HUMAN
NC score	0.796460 (rank : 32)	θ value	9.56915e-18 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS6_MOUSE
NC score	0.794371 (rank : 33)	θ value	1.92812e-18 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS6_HUMAN
NC score	0.770881 (rank : 34)	θ value	1.16975e-15 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	80	Shared Neighborhood Hits	43
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

AXN1_MOUSE
NC score	0.640013 (rank : 35)	θ value	1.133e-10 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

AXN1_HUMAN
NC score	0.621802 (rank : 36)	θ value	7.34386e-10 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

RGS3_HUMAN
NC score	0.611447 (rank : 37)	θ value	1.38178e-16 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	1375	Shared Neighborhood Hits	54
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

AXN2_HUMAN
NC score	0.608491 (rank : 38)	θ value	1.38499e-08 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	102	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN2_MOUSE
NC score	0.596286 (rank : 39)	θ value	1.53129e-07 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

RGS3_MOUSE
NC score	0.545917 (rank : 40)	θ value	1.38178e-16 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	1621	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AKA10_MOUSE
NC score	0.340628 (rank : 41)	θ value	7.1131e-05 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

AKA10_HUMAN
NC score	0.340573 (rank : 42)	θ value	7.1131e-05 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SNX13_MOUSE
NC score	0.278545 (rank : 43)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNX13_HUMAN
NC score	0.272355 (rank : 44)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

SNX25_HUMAN
NC score	0.124365 (rank : 45)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

SNX14_MOUSE
NC score	0.052200 (rank : 46)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

CTDP1_HUMAN
NC score	0.043365 (rank : 47)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	416	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

CCD22_HUMAN
NC score	0.042290 (rank : 48)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

ARHGB_HUMAN
NC score	0.034327 (rank : 49)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	375	Shared Neighborhood Hits	12
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

LYSM3_MOUSE
NC score	0.033087 (rank : 50)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LE3	Gene names	Lysmd3
Domain Architecture	No domain graphic available
Description	LysM and putative peptidoglycan-binding domain-containing protein 3.

CABL2_HUMAN
NC score	0.029118 (rank : 51)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

RPP25_HUMAN
NC score	0.025801 (rank : 52)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BUL9, Q9NX88	Gene names	RPP25
Domain Architecture	No domain graphic available
Description	Ribonuclease P protein subunit p25 (EC 3.1.26.5) (RNase P protein subunit p25).

PELP1_HUMAN
NC score	0.023804 (rank : 53)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	596	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

ZNT3_HUMAN
NC score	0.020795 (rank : 54)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99726	Gene names	SLC30A3, ZNT3
Domain Architecture
Description	Zinc transporter 3 (ZnT-3) (Solute carrier family 30 member 3).

JIP2_HUMAN
NC score	0.019944 (rank : 55)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PCLO_HUMAN
NC score	0.016304 (rank : 56)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	2046	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PTN23_HUMAN
NC score	0.016044 (rank : 57)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	646	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CS029_MOUSE
NC score	0.015923 (rank : 58)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

MLL2_HUMAN
NC score	0.015385 (rank : 59)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	1788	Shared Neighborhood Hits	16
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

KCNH2_HUMAN
NC score	0.014110 (rank : 60)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.013127 (rank : 61)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

SMRC2_HUMAN
NC score	0.011412 (rank : 62)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	499	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

MELPH_MOUSE
NC score	0.011092 (rank : 63)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

CRCM_HUMAN
NC score	0.009188 (rank : 64)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	520	Shared Neighborhood Hits	8
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

SPTA1_HUMAN
NC score	0.008121 (rank : 65)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	748	Shared Neighborhood Hits	6
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
NC score	0.007901 (rank : 66)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	675	Shared Neighborhood Hits	8
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ASPP1_MOUSE
NC score	0.007448 (rank : 67)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	1244	Shared Neighborhood Hits	12
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RGNEF_MOUSE
NC score	0.006962 (rank : 68)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	641	Shared Neighborhood Hits	9
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

PLVAP_MOUSE
NC score	0.006740 (rank : 69)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	210	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VC4, Q99JB1	Gene names	Plvap, Pv1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (MECA-32 antigen).

ZFY28_HUMAN
NC score	0.006446 (rank : 70)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

PCNT_MOUSE
NC score	0.006336 (rank : 71)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	1207	Shared Neighborhood Hits	12
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

LY10_HUMAN
NC score	0.005285 (rank : 72)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MTMR5_HUMAN
NC score	0.005013 (rank : 73)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

ITA2B_MOUSE
NC score	0.004457 (rank : 74)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QUM0, Q64229, Q9Z2M0	Gene names	Itga2b
Domain Architecture
Description	Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen) [Contains: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain].

KIF1B_HUMAN
NC score	0.002761 (rank : 75)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

MAST3_HUMAN
NC score	0.000544 (rank : 76)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	1128	Shared Neighborhood Hits	9
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

KI21A_MOUSE
NC score	0.000417 (rank : 77)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	1317	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KI21A_HUMAN
NC score	-0.000478 (rank : 78)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	1543	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KLF4_HUMAN
NC score	-0.003312 (rank : 79)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	709	Shared Neighborhood Hits	2
SwissProt Accessions	O43474, P78338, Q9UNP3	Gene names	KLF4, EZF, GKLF
Domain Architecture
Description	Krueppel-like factor 4 (Epithelial zinc-finger protein EZF) (Gut- enriched krueppel-like factor).