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Network neighborhood for query Sequence : EST1A_HUMAN

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EST1A_HUMAN
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EST1A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

EST1A_MOUSE
θ value	0 (rank : 2)	NC score	0.966858 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	138	Shared Neighborhood Hits	43
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

SMG7_HUMAN
θ value	4.15078e-21 (rank : 3)	NC score	0.532098 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

SMG7_MOUSE
θ value	9.24701e-21 (rank : 4)	NC score	0.531325 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

SMG5_MOUSE
θ value	9.90251e-15 (rank : 5)	NC score	0.464552 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

SMG5_HUMAN
θ value	1.42992e-13 (rank : 6)	NC score	0.439479 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	180	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

CA026_MOUSE
θ value	2.52405e-10 (rank : 7)	NC score	0.338044 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

CA026_HUMAN
θ value	2.36244e-08 (rank : 8)	NC score	0.312018 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T5J6, Q8NEK9, Q9BZQ7, Q9NXQ0	Gene names	C1orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26.

SPT5H_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.132605 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	436	Shared Neighborhood Hits	12
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.00665767 (rank : 10)	NC score	0.128246 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	437	Shared Neighborhood Hits	8
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

NPBL_MOUSE
θ value	0.0252991 (rank : 11)	NC score	0.051816 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	1041	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MAST2_MOUSE
θ value	0.0431538 (rank : 12)	NC score	0.017608 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	1110	Shared Neighborhood Hits	10
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

KLC1_HUMAN
θ value	0.0563607 (rank : 13)	NC score	0.071678 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	471	Shared Neighborhood Hits	22
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

ZNFX1_MOUSE
θ value	0.0563607 (rank : 14)	NC score	0.063165 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	407	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

EHMT2_HUMAN
θ value	0.0736092 (rank : 15)	NC score	0.040935 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	0.0736092 (rank : 16)	NC score	0.039537 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	750	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ZFP91_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.011355 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	769	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JP5, Q86V47, Q96JP4, Q96QA3	Gene names	ZFP91
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 homolog (Zfp-91).

MPP8_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.038764 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	948	Shared Neighborhood Hits	30
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CAR11_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.048025 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	690	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

HOOK3_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.033770 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	1070	Shared Neighborhood Hits	28
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	0.163984 (rank : 21)	NC score	0.034408 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	1007	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

CP135_HUMAN
θ value	0.21417 (rank : 22)	NC score	0.036570 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	1290	Shared Neighborhood Hits	30
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

NASP_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.056054 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	709	Shared Neighborhood Hits	27
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

THOC2_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.071605 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	337	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

ZFP91_MOUSE
θ value	0.279714 (rank : 25)	NC score	0.009663 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	742	Shared Neighborhood Hits	5
SwissProt Accessions	Q62511, Q8BPY3, Q8C2B4	Gene names	Zfp91, Pzf
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 (Zfp-91) (Zinc finger protein PZF) (Penta Zf protein).

RRBP1_MOUSE
θ value	0.365318 (rank : 26)	NC score	0.027616 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	1650	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SOX9_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.028271 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	210	Shared Neighborhood Hits	6
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

KLC1_MOUSE
θ value	0.47712 (rank : 28)	NC score	0.062651 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	357	Shared Neighborhood Hits	24
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

CP135_MOUSE
θ value	0.62314 (rank : 29)	NC score	0.034243 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	1278	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

E41L2_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.031609 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	287	Shared Neighborhood Hits	11
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
θ value	0.62314 (rank : 31)	NC score	0.026372 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	459	Shared Neighborhood Hits	19
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

ITPR3_MOUSE
θ value	0.813845 (rank : 32)	NC score	0.019016 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

MICA1_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.032086 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	400	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

NSBP1_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.057261 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	251	Shared Neighborhood Hits	11
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

MORC4_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.042979 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	244	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

DYRK3_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.006498 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	798	Shared Neighborhood Hits	7
SwissProt Accessions	O43781	Gene names	DYRK3
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1).

PC11X_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.008680 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

RRS1_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.047776 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q15050, Q9BUX8	Gene names	RRS1, KIAA0112, RRR
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

TTC16_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.029279 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

FXR1_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.018931 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

KLC2_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.052756 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	227	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

MYH9_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.019693 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	1829	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CRSP2_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.050633 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	380	Shared Neighborhood Hits	10
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

TTLL7_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.020339 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZT98, Q5TAX8, Q5TAX9, Q6P990, Q86YS1, Q9H5U4	Gene names	TTLL7
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 7 (Protein NYD-SP30).

ZC3H6_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.022226 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	239	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

AKA10_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.029447 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

DCAK3_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.004410 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	888	Shared Neighborhood Hits	11
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

GCYB2_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.017470 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	O75343, Q9NZ64	Gene names	GUCY1B2
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-2 (EC 4.6.1.2) (GCS-beta-2).

RENT2_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.034295 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	618	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

TF3C3_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.031247 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

EPIPL_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.017429 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	P58107, Q76E58	Gene names	EPPK1, EPIPL
Domain Architecture
Description	Epiplakin (450 kDa epidermal antigen).

GIDRP_MOUSE
θ value	4.03905 (rank : 52)	NC score	0.020992 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJM3, Q3UGJ8, Q5U5U8	Gene names	Gidrp88, D19Ertd386e
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 homolog.

IQEC2_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.015848 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

LATS1_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.009982 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	1027	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

MAST2_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.012575 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	1189	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST4_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.009457 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	1804	Shared Neighborhood Hits	20
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NADAP_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.027029 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

RRS1_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.041000 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYH6, Q3UQW6, Q9CS27, Q9D2B2, Q9D6M6, Q9JJC1	Gene names	Rrs1, Rrr
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

SETD2_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.038073 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	412	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SM1L2_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.019141 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	1019	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

TRI35_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.012748 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	465	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TSKS_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.025155 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

AKA10_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.026345 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

CROCC_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.021336 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	1460	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOG8A_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.025702 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	635	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA2_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.023942 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	944	Shared Neighborhood Hits	27
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

IF4G1_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.023368 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	534	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MAML1_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.016035 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

RAE1A_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.013304 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O08602	Gene names	Raet1a
Domain Architecture
Description	Retinoic acid early inducible protein 1 alpha precursor (RAE-1alpha).

RBM25_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.036281 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	682	Shared Neighborhood Hits	24
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SFRS4_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.022678 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	406	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TIM_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.016949 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1X4, Q63ZX9, Q6P204, Q6PDL4, Q7TPV8, Q8R0Q2, Q9R268, Q9Z0E7	Gene names	Timeless, Tim1, Timeless1
Domain Architecture	No domain graphic available
Description	Timeless homolog (mTim).

UB2L6_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.009884 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZU9, Q922F1, Q9CQN0	Gene names	Ube2l6, Ubce8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcM8).

ZFY16_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.011032 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

AKAP9_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.023640 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	1710	Shared Neighborhood Hits	34
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CASC5_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.022629 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	376	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

KLC2_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.042228 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	244	Shared Neighborhood Hits	18
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

MAGC1_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.009529 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	431	Shared Neighborhood Hits	9
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

NKTR_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.013995 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	18
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TOM70_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.015554 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.015483 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

ZBT7A_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.000294 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	823	Shared Neighborhood Hits	4
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).

ZNFX1_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.035164 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	308	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ALX3_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.002071 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	386	Shared Neighborhood Hits	2
SwissProt Accessions	O70137	Gene names	Alx3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

CI047_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.020837 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZRZ4, Q5SQD7, Q7Z568, Q8N1V4	Gene names	C9orf47
Domain Architecture	No domain graphic available
Description	Protein C9orf47 precursor.

CN102_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.013194 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z3, Q9NWH6	Gene names	C14orf102
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102.

CROCC_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.018951 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	1409	Shared Neighborhood Hits	34
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GIT2_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.008749 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	381	Shared Neighborhood Hits	7
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

KLC3_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.038256 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	135	Shared Neighborhood Hits	13
SwissProt Accessions	Q91W40, Q3TZ56	Gene names	Klc3
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3.

NEBU_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.008434 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	420	Shared Neighborhood Hits	6
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

PLEC1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.020281 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	1326	Shared Neighborhood Hits	32
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SCG1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.023814 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

SF3A1_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.015770 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A1_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.015975 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

TF7L2_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.008828 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TULP1_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.011704 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

UACA_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.019371 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	1620	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UTP18_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.010444 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SSI6	Gene names	Utp18, Wdr50
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

NIPBL_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.059632 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	1311	Shared Neighborhood Hits	39
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

REN3B_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.054426 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	412	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

Hits sorted by NC score

EST1A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

EST1A_MOUSE
NC score	0.966858 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	138	Shared Neighborhood Hits	43
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

SMG7_HUMAN
NC score	0.532098 (rank : 3)	θ value	4.15078e-21 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

SMG7_MOUSE
NC score	0.531325 (rank : 4)	θ value	9.24701e-21 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

SMG5_MOUSE
NC score	0.464552 (rank : 5)	θ value	9.90251e-15 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

SMG5_HUMAN
NC score	0.439479 (rank : 6)	θ value	1.42992e-13 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	180	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

CA026_MOUSE
NC score	0.338044 (rank : 7)	θ value	2.52405e-10 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

CA026_HUMAN
NC score	0.312018 (rank : 8)	θ value	2.36244e-08 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T5J6, Q8NEK9, Q9BZQ7, Q9NXQ0	Gene names	C1orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26.

SPT5H_HUMAN
NC score	0.132605 (rank : 9)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	436	Shared Neighborhood Hits	12
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
NC score	0.128246 (rank : 10)	θ value	0.00665767 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	437	Shared Neighborhood Hits	8
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

KLC1_HUMAN
NC score	0.071678 (rank : 11)	θ value	0.0563607 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	471	Shared Neighborhood Hits	22
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

THOC2_HUMAN
NC score	0.071605 (rank : 12)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	337	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

ZNFX1_MOUSE
NC score	0.063165 (rank : 13)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	407	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

KLC1_MOUSE
NC score	0.062651 (rank : 14)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	357	Shared Neighborhood Hits	24
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

NIPBL_HUMAN
NC score	0.059632 (rank : 15)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	1311	Shared Neighborhood Hits	39
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NSBP1_HUMAN
NC score	0.057261 (rank : 16)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	251	Shared Neighborhood Hits	11
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NASP_HUMAN
NC score	0.056054 (rank : 17)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	709	Shared Neighborhood Hits	27
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

REN3B_HUMAN
NC score	0.054426 (rank : 18)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	412	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

KLC2_HUMAN
NC score	0.052756 (rank : 19)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	227	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

NPBL_MOUSE
NC score	0.051816 (rank : 20)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	1041	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CRSP2_HUMAN
NC score	0.050633 (rank : 21)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	380	Shared Neighborhood Hits	10
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CAR11_HUMAN
NC score	0.048025 (rank : 22)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	690	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

RRS1_HUMAN
NC score	0.047776 (rank : 23)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q15050, Q9BUX8	Gene names	RRS1, KIAA0112, RRR
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

MORC4_HUMAN
NC score	0.042979 (rank : 24)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	244	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

KLC2_MOUSE
NC score	0.042228 (rank : 25)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	244	Shared Neighborhood Hits	18
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

RRS1_MOUSE
NC score	0.041000 (rank : 26)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYH6, Q3UQW6, Q9CS27, Q9D2B2, Q9D6M6, Q9JJC1	Gene names	Rrs1, Rrr
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

EHMT2_HUMAN
NC score	0.040935 (rank : 27)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.039537 (rank : 28)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	750	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MPP8_HUMAN
NC score	0.038764 (rank : 29)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	948	Shared Neighborhood Hits	30
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

KLC3_MOUSE
NC score	0.038256 (rank : 30)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	135	Shared Neighborhood Hits	13
SwissProt Accessions	Q91W40, Q3TZ56	Gene names	Klc3
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3.

SETD2_HUMAN
NC score	0.038073 (rank : 31)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	412	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

CP135_HUMAN
NC score	0.036570 (rank : 32)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	1290	Shared Neighborhood Hits	30
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

RBM25_HUMAN
NC score	0.036281 (rank : 33)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	682	Shared Neighborhood Hits	24
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

ZNFX1_HUMAN
NC score	0.035164 (rank : 34)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	308	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

HOOK3_MOUSE
NC score	0.034408 (rank : 35)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	1007	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

RENT2_HUMAN
NC score	0.034295 (rank : 36)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	618	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

CP135_MOUSE
NC score	0.034243 (rank : 37)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	1278	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

HOOK3_HUMAN
NC score	0.033770 (rank : 38)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	1070	Shared Neighborhood Hits	28
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

MICA1_MOUSE
NC score	0.032086 (rank : 39)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	400	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

E41L2_HUMAN
NC score	0.031609 (rank : 40)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	287	Shared Neighborhood Hits	11
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

TF3C3_HUMAN
NC score	0.031247 (rank : 41)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

AKA10_HUMAN
NC score	0.029447 (rank : 42)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

TTC16_HUMAN
NC score	0.029279 (rank : 43)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

SOX9_HUMAN
NC score	0.028271 (rank : 44)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	210	Shared Neighborhood Hits	6
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

RRBP1_MOUSE
NC score	0.027616 (rank : 45)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	1650	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NADAP_HUMAN
NC score	0.027029 (rank : 46)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

E41L2_MOUSE
NC score	0.026372 (rank : 47)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	459	Shared Neighborhood Hits	19
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

AKA10_MOUSE
NC score	0.026345 (rank : 48)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

GOG8A_HUMAN
NC score	0.025702 (rank : 49)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	635	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

TSKS_HUMAN
NC score	0.025155 (rank : 50)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

GOGA2_MOUSE
NC score	0.023942 (rank : 51)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	944	Shared Neighborhood Hits	27
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

SCG1_MOUSE
NC score	0.023814 (rank : 52)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

AKAP9_HUMAN
NC score	0.023640 (rank : 53)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	1710	Shared Neighborhood Hits	34
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

IF4G1_MOUSE
NC score	0.023368 (rank : 54)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	534	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

SFRS4_MOUSE
NC score	0.022678 (rank : 55)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	406	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

CASC5_HUMAN
NC score	0.022629 (rank : 56)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	376	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

ZC3H6_MOUSE
NC score	0.022226 (rank : 57)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	239	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CROCC_MOUSE
NC score	0.021336 (rank : 58)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	1460	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GIDRP_MOUSE
NC score	0.020992 (rank : 59)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJM3, Q3UGJ8, Q5U5U8	Gene names	Gidrp88, D19Ertd386e
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 homolog.

CI047_HUMAN
NC score	0.020837 (rank : 60)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZRZ4, Q5SQD7, Q7Z568, Q8N1V4	Gene names	C9orf47
Domain Architecture	No domain graphic available
Description	Protein C9orf47 precursor.

TTLL7_HUMAN
NC score	0.020339 (rank : 61)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZT98, Q5TAX8, Q5TAX9, Q6P990, Q86YS1, Q9H5U4	Gene names	TTLL7
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 7 (Protein NYD-SP30).

PLEC1_HUMAN
NC score	0.020281 (rank : 62)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	1326	Shared Neighborhood Hits	32
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MYH9_MOUSE
NC score	0.019693 (rank : 63)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	1829	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

UACA_MOUSE
NC score	0.019371 (rank : 64)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	1620	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

SM1L2_HUMAN
NC score	0.019141 (rank : 65)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	1019	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

ITPR3_MOUSE
NC score	0.019016 (rank : 66)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

CROCC_HUMAN
NC score	0.018951 (rank : 67)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	1409	Shared Neighborhood Hits	34
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

FXR1_MOUSE
NC score	0.018931 (rank : 68)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

MAST2_MOUSE
NC score	0.017608 (rank : 69)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	1110	Shared Neighborhood Hits	10
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

GCYB2_HUMAN
NC score	0.017470 (rank : 70)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	O75343, Q9NZ64	Gene names	GUCY1B2
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-2 (EC 4.6.1.2) (GCS-beta-2).

EPIPL_HUMAN
NC score	0.017429 (rank : 71)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	P58107, Q76E58	Gene names	EPPK1, EPIPL
Domain Architecture
Description	Epiplakin (450 kDa epidermal antigen).

TIM_MOUSE
NC score	0.016949 (rank : 72)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1X4, Q63ZX9, Q6P204, Q6PDL4, Q7TPV8, Q8R0Q2, Q9R268, Q9Z0E7	Gene names	Timeless, Tim1, Timeless1
Domain Architecture	No domain graphic available
Description	Timeless homolog (mTim).

MAML1_HUMAN
NC score	0.016035 (rank : 73)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SF3A1_MOUSE
NC score	0.015975 (rank : 74)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

IQEC2_MOUSE
NC score	0.015848 (rank : 75)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

SF3A1_HUMAN
NC score	0.015770 (rank : 76)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

TOM70_HUMAN
NC score	0.015554 (rank : 77)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_MOUSE
NC score	0.015483 (rank : 78)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

NKTR_MOUSE
NC score	0.013995 (rank : 79)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	18
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RAE1A_MOUSE
NC score	0.013304 (rank : 80)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O08602	Gene names	Raet1a
Domain Architecture
Description	Retinoic acid early inducible protein 1 alpha precursor (RAE-1alpha).

CN102_HUMAN
NC score	0.013194 (rank : 81)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z3, Q9NWH6	Gene names	C14orf102
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102.

TRI35_MOUSE
NC score	0.012748 (rank : 82)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	465	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

MAST2_HUMAN
NC score	0.012575 (rank : 83)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	1189	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TULP1_HUMAN
NC score	0.011704 (rank : 84)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

ZFP91_HUMAN
NC score	0.011355 (rank : 85)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	769	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JP5, Q86V47, Q96JP4, Q96QA3	Gene names	ZFP91
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 homolog (Zfp-91).

ZFY16_MOUSE
NC score	0.011032 (rank : 86)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

UTP18_MOUSE
NC score	0.010444 (rank : 87)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SSI6	Gene names	Utp18, Wdr50
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

LATS1_MOUSE
NC score	0.009982 (rank : 88)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	1027	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

UB2L6_MOUSE
NC score	0.009884 (rank : 89)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZU9, Q922F1, Q9CQN0	Gene names	Ube2l6, Ubce8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcM8).

ZFP91_MOUSE
NC score	0.009663 (rank : 90)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	742	Shared Neighborhood Hits	5
SwissProt Accessions	Q62511, Q8BPY3, Q8C2B4	Gene names	Zfp91, Pzf
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 (Zfp-91) (Zinc finger protein PZF) (Penta Zf protein).

MAGC1_HUMAN
NC score	0.009529 (rank : 91)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	431	Shared Neighborhood Hits	9
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MAST4_HUMAN
NC score	0.009457 (rank : 92)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	1804	Shared Neighborhood Hits	20
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

TF7L2_HUMAN
NC score	0.008828 (rank : 93)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

GIT2_HUMAN
NC score	0.008749 (rank : 94)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	381	Shared Neighborhood Hits	7
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

PC11X_HUMAN
NC score	0.008680 (rank : 95)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

NEBU_HUMAN
NC score	0.008434 (rank : 96)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	420	Shared Neighborhood Hits	6
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

DYRK3_HUMAN
NC score	0.006498 (rank : 97)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	798	Shared Neighborhood Hits	7
SwissProt Accessions	O43781	Gene names	DYRK3
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1).

DCAK3_HUMAN
NC score	0.004410 (rank : 98)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	888	Shared Neighborhood Hits	11
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

ALX3_MOUSE
NC score	0.002071 (rank : 99)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	386	Shared Neighborhood Hits	2
SwissProt Accessions	O70137	Gene names	Alx3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

ZBT7A_HUMAN
NC score	0.000294 (rank : 100)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	823	Shared Neighborhood Hits	4
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).