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Network neighborhood for query Sequence : BORG1_HUMAN

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BORG1_HUMAN
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BORG1_HUMAN
θ value	5.09482e-120 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

BORG1_MOUSE
θ value	3.91911e-104 (rank : 2)	NC score	0.983409 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q8JZX9	Gene names	Cdc42ep2, Borg1, Cep2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

BORG2_MOUSE
θ value	3.16345e-37 (rank : 3)	NC score	0.892389 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQC5, Q3UD77, Q8BVR7	Gene names	Cdc42ep3, Borg2, Cep3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2).

BORG2_HUMAN
θ value	5.0505e-35 (rank : 4)	NC score	0.891020 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKI2, O95353, Q9UQJ0	Gene names	CDC42EP3, BORG2, CEP3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein).

BORG5_HUMAN
θ value	9.90251e-15 (rank : 5)	NC score	0.673491 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

BORG4_MOUSE
θ value	1.68911e-14 (rank : 6)	NC score	0.682767 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM96, Q3TNF3, Q9QZT8	Gene names	Cdc42ep4, Borg4, Cep4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

BORG4_HUMAN
θ value	4.16044e-13 (rank : 7)	NC score	0.685475 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H3Q1, O95828, Q96FT3	Gene names	CDC42EP4, BORG4, CEP4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

BORG5_MOUSE
θ value	1.02475e-11 (rank : 8)	NC score	0.676451 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	Q91W92, Q9D8M1	Gene names	Cdc42ep1, Borg5, Cep1
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5).

BORG3_MOUSE
θ value	9.92553e-07 (rank : 9)	NC score	0.615372 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0X0, Q3SYK1, Q9QZT9	Gene names	Cdc42ep5, Borg3, Cep5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

BORG3_HUMAN
θ value	1.69304e-06 (rank : 10)	NC score	0.625600 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZY7, Q8TB51	Gene names	CDC42EP5, BORG3, CEP5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

TGIF2_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.051843 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZN2	Gene names	TGIF2
Domain Architecture
Description	Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3'-interacting factor 2) (TGF(beta)-induced transcription factor 2).

SON_HUMAN
θ value	0.125558 (rank : 12)	NC score	0.064941 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	1568	Shared Neighborhood Hits	42
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ZFHX2_HUMAN
θ value	0.163984 (rank : 13)	NC score	0.036463 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	1178	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

SP5_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.010529 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	832	Shared Neighborhood Hits	13
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

ZIM10_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.031806 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	577	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

GSCR1_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.046804 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	674	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MEF2D_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.025671 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

SALL2_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.013004 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	835	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

ZN341_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.006197 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	803	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

CIC_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.037251 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	742	Shared Neighborhood Hits	22
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FMN1A_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.055623 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	423	Shared Neighborhood Hits	16
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.054060 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMN2_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.052662 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	484	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MRCKB_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.006679 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	2239	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKG_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.006973 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	1466	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

ZCHC8_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.034835 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

BAZ2A_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.024734 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	780	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

ITB4_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.011042 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	458	Shared Neighborhood Hits	2
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

RFX1_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.023324 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	181	Shared Neighborhood Hits	7
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

DAG1_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.030089 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

SP5_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.009080 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	821	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

TGIF2_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.039886 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0Y1	Gene names	Tgif2
Domain Architecture	No domain graphic available
Description	Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3'-interacting factor 2) (TGF(beta)-induced transcription factor 2).

WASF2_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.024907 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

ZBTB4_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.009658 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	926	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

CIC_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.039260 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	992	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FYB_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.025049 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	379	Shared Neighborhood Hits	11
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

HXA3_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.010143 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	558	Shared Neighborhood Hits	11
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

RX_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.009904 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SON_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.049473 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	957	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

T22D4_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.031531 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	403	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

IER5_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.025287 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

NIBL_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.030494 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

PAK2_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.004978 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	862	Shared Neighborhood Hits	8
SwissProt Accessions	Q13177, Q13154	Gene names	PAK2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase).

PAK2_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.004985 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	858	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

RANB9_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.025008 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RBM12_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.024642 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	298	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

FMN2_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.049301 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMNL_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.033026 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	529	Shared Neighborhood Hits	20
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PCQAP_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.020928 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	549	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

SAPS1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.023782 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	704	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SOX8_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.011339 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SRPK1_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.008129 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

ALEX_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.021610 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

EPN1_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.013795 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

IASPP_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.011779 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	1024	Shared Neighborhood Hits	21
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NIBL_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.025946 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1F1	Gene names
Domain Architecture	No domain graphic available
Description	Niban-like protein.

PKN3_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.005538 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	1009	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

REXO1_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.012994 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

SASH1_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.019240 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SPN90_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.014428 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

ZN694_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.002079 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	764	Shared Neighborhood Hits	8
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.

PGCA_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.007775 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	821	Shared Neighborhood Hits	9
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

RAPH1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.022796 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	593	Shared Neighborhood Hits	21
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SCN3A_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.005446 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SF3A2_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.022248 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SYNJ1_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.013784 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	516	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

UBP53_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.009712 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

Hits sorted by NC score

BORG1_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.09482e-120 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

BORG1_MOUSE
NC score	0.983409 (rank : 2)	θ value	3.91911e-104 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q8JZX9	Gene names	Cdc42ep2, Borg1, Cep2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

BORG2_MOUSE
NC score	0.892389 (rank : 3)	θ value	3.16345e-37 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQC5, Q3UD77, Q8BVR7	Gene names	Cdc42ep3, Borg2, Cep3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2).

BORG2_HUMAN
NC score	0.891020 (rank : 4)	θ value	5.0505e-35 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKI2, O95353, Q9UQJ0	Gene names	CDC42EP3, BORG2, CEP3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein).

BORG4_HUMAN
NC score	0.685475 (rank : 5)	θ value	4.16044e-13 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H3Q1, O95828, Q96FT3	Gene names	CDC42EP4, BORG4, CEP4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

BORG4_MOUSE
NC score	0.682767 (rank : 6)	θ value	1.68911e-14 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM96, Q3TNF3, Q9QZT8	Gene names	Cdc42ep4, Borg4, Cep4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

BORG5_MOUSE
NC score	0.676451 (rank : 7)	θ value	1.02475e-11 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	Q91W92, Q9D8M1	Gene names	Cdc42ep1, Borg5, Cep1
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5).

BORG5_HUMAN
NC score	0.673491 (rank : 8)	θ value	9.90251e-15 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

BORG3_HUMAN
NC score	0.625600 (rank : 9)	θ value	1.69304e-06 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZY7, Q8TB51	Gene names	CDC42EP5, BORG3, CEP5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

BORG3_MOUSE
NC score	0.615372 (rank : 10)	θ value	9.92553e-07 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0X0, Q3SYK1, Q9QZT9	Gene names	Cdc42ep5, Borg3, Cep5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

SON_HUMAN
NC score	0.064941 (rank : 11)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	1568	Shared Neighborhood Hits	42
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

FMN1A_MOUSE
NC score	0.055623 (rank : 12)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	423	Shared Neighborhood Hits	16
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
NC score	0.054060 (rank : 13)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMN2_HUMAN
NC score	0.052662 (rank : 14)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	484	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

TGIF2_HUMAN
NC score	0.051843 (rank : 15)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZN2	Gene names	TGIF2
Domain Architecture
Description	Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3'-interacting factor 2) (TGF(beta)-induced transcription factor 2).

SON_MOUSE
NC score	0.049473 (rank : 16)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	957	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

FMN2_MOUSE
NC score	0.049301 (rank : 17)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

GSCR1_HUMAN
NC score	0.046804 (rank : 18)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	674	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

TGIF2_MOUSE
NC score	0.039886 (rank : 19)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0Y1	Gene names	Tgif2
Domain Architecture	No domain graphic available
Description	Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3'-interacting factor 2) (TGF(beta)-induced transcription factor 2).

CIC_HUMAN
NC score	0.039260 (rank : 20)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	992	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
NC score	0.037251 (rank : 21)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	742	Shared Neighborhood Hits	22
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ZFHX2_HUMAN
NC score	0.036463 (rank : 22)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	1178	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ZCHC8_MOUSE
NC score	0.034835 (rank : 23)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

FMNL_HUMAN
NC score	0.033026 (rank : 24)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	529	Shared Neighborhood Hits	20
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

ZIM10_HUMAN
NC score	0.031806 (rank : 25)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	577	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

T22D4_HUMAN
NC score	0.031531 (rank : 26)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	403	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

NIBL_HUMAN
NC score	0.030494 (rank : 27)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

DAG1_HUMAN
NC score	0.030089 (rank : 28)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

NIBL_MOUSE
NC score	0.025946 (rank : 29)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1F1	Gene names
Domain Architecture	No domain graphic available
Description	Niban-like protein.

MEF2D_MOUSE
NC score	0.025671 (rank : 30)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

IER5_MOUSE
NC score	0.025287 (rank : 31)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

FYB_HUMAN
NC score	0.025049 (rank : 32)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	379	Shared Neighborhood Hits	11
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

RANB9_HUMAN
NC score	0.025008 (rank : 33)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

WASF2_HUMAN
NC score	0.024907 (rank : 34)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

BAZ2A_HUMAN
NC score	0.024734 (rank : 35)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	780	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

RBM12_HUMAN
NC score	0.024642 (rank : 36)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	298	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SAPS1_HUMAN
NC score	0.023782 (rank : 37)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	704	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

RFX1_MOUSE
NC score	0.023324 (rank : 38)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	181	Shared Neighborhood Hits	7
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

RAPH1_HUMAN
NC score	0.022796 (rank : 39)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	593	Shared Neighborhood Hits	21
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SF3A2_MOUSE
NC score	0.022248 (rank : 40)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

ALEX_MOUSE
NC score	0.021610 (rank : 41)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

PCQAP_HUMAN
NC score	0.020928 (rank : 42)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	549	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

SASH1_MOUSE
NC score	0.019240 (rank : 43)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SPN90_HUMAN
NC score	0.014428 (rank : 44)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

EPN1_HUMAN
NC score	0.013795 (rank : 45)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

SYNJ1_MOUSE
NC score	0.013784 (rank : 46)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	516	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SALL2_HUMAN
NC score	0.013004 (rank : 47)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	835	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

REXO1_HUMAN
NC score	0.012994 (rank : 48)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

IASPP_MOUSE
NC score	0.011779 (rank : 49)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	1024	Shared Neighborhood Hits	21
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SOX8_HUMAN
NC score	0.011339 (rank : 50)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

ITB4_HUMAN
NC score	0.011042 (rank : 51)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	458	Shared Neighborhood Hits	2
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

SP5_HUMAN
NC score	0.010529 (rank : 52)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	832	Shared Neighborhood Hits	13
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

HXA3_MOUSE
NC score	0.010143 (rank : 53)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	558	Shared Neighborhood Hits	11
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

RX_HUMAN
NC score	0.009904 (rank : 54)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

UBP53_MOUSE
NC score	0.009712 (rank : 55)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

ZBTB4_HUMAN
NC score	0.009658 (rank : 56)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	926	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

SP5_MOUSE
NC score	0.009080 (rank : 57)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	821	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

SRPK1_HUMAN
NC score	0.008129 (rank : 58)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

PGCA_HUMAN
NC score	0.007775 (rank : 59)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	821	Shared Neighborhood Hits	9
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MRCKG_MOUSE
NC score	0.006973 (rank : 60)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	1466	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MRCKB_HUMAN
NC score	0.006679 (rank : 61)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	2239	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ZN341_HUMAN
NC score	0.006197 (rank : 62)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	803	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

PKN3_MOUSE
NC score	0.005538 (rank : 63)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	1009	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

SCN3A_HUMAN
NC score	0.005446 (rank : 64)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

PAK2_MOUSE
NC score	0.004985 (rank : 65)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	858	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

PAK2_HUMAN
NC score	0.004978 (rank : 66)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	862	Shared Neighborhood Hits	8
SwissProt Accessions	Q13177, Q13154	Gene names	PAK2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase).

ZN694_HUMAN
NC score	0.002079 (rank : 67)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	764	Shared Neighborhood Hits	8
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.