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Network neighborhood for query Sequence : MLH3_HUMAN

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MLH3_HUMAN
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MLH3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

MLH1_HUMAN
θ value	3.07116e-24 (rank : 2)	NC score	0.651832 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

MLH1_MOUSE
θ value	1.29031e-22 (rank : 3)	NC score	0.644750 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

PMS1_HUMAN
θ value	6.40375e-22 (rank : 4)	NC score	0.589997 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	126	Shared Neighborhood Hits	8
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

PMS2_HUMAN
θ value	6.85773e-16 (rank : 5)	NC score	0.568280 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS2_MOUSE
θ value	2.88119e-14 (rank : 6)	NC score	0.567305 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

ZN514_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.003607 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	738	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K75	Gene names	ZNF514
Domain Architecture
Description	Zinc finger protein 514.

SETX_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.046369 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	368	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

TPR_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.018430 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	1921	Shared Neighborhood Hits	15
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

DMP1_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.046520 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PREP_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.042912 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K411, Q3THC4, Q3TJI1, Q3TPP0, Q3URQ8, Q4KUG2, Q4KUG3, Q6ZPX6, Q922N1, Q9CV63	Gene names	Pitrm1, Kiaa1104, Ntup1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (Pitrilysin metalloproteinase 1).

WWP1_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.024995 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	262	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP1_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.024248 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

CSPG2_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.014640 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	681	Shared Neighborhood Hits	5
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

UBP31_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.023635 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CT2NL_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.024870 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	1059	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DIAP3_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.021270 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	221	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

CIR_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.034583 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

OPTN_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.014477 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	1120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PDZK4_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.019216 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PML_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.023060 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

CT2NL_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.025501 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	902	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

EP15_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.015498 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	1021	Shared Neighborhood Hits	11
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MYH3_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.008172 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	1660	Shared Neighborhood Hits	14
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PALB2_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.026015 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

ZN318_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.023811 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	642	Shared Neighborhood Hits	10
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

BRCA2_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.020352 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	202	Shared Neighborhood Hits	4
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

FGD3_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.009609 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	249	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

STAM2_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.011492 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

DPOLZ_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.014739 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

K0408_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.027307 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

TRHY_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.010819 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	1385	Shared Neighborhood Hits	15
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ASPP2_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.008720 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	1156	Shared Neighborhood Hits	12
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

DCP1A_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.014671 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

DNMT1_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.013391 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

IWS1_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.010993 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	1241	Shared Neighborhood Hits	11
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LRP1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.004106 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	617	Shared Neighborhood Hits	4
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MMAA_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.017924 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IVH4	Gene names	MMAA
Domain Architecture
Description	Methylmalonic aciduria type A protein, mitochondrial precursor.

PPRB_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.013309 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	311	Shared Neighborhood Hits	4
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SYCP1_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.010069 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	1313	Shared Neighborhood Hits	13
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TCPA1_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.010722 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPA2_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.010745 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

Hits sorted by NC score

MLH3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

MLH1_HUMAN
NC score	0.651832 (rank : 2)	θ value	3.07116e-24 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

MLH1_MOUSE
NC score	0.644750 (rank : 3)	θ value	1.29031e-22 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

PMS1_HUMAN
NC score	0.589997 (rank : 4)	θ value	6.40375e-22 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	126	Shared Neighborhood Hits	8
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

PMS2_HUMAN
NC score	0.568280 (rank : 5)	θ value	6.85773e-16 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS2_MOUSE
NC score	0.567305 (rank : 6)	θ value	2.88119e-14 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

DMP1_HUMAN
NC score	0.046520 (rank : 7)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

SETX_HUMAN
NC score	0.046369 (rank : 8)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	368	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

PREP_MOUSE
NC score	0.042912 (rank : 9)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K411, Q3THC4, Q3TJI1, Q3TPP0, Q3URQ8, Q4KUG2, Q4KUG3, Q6ZPX6, Q922N1, Q9CV63	Gene names	Pitrm1, Kiaa1104, Ntup1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (Pitrilysin metalloproteinase 1).

CIR_MOUSE
NC score	0.034583 (rank : 10)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

K0408_HUMAN
NC score	0.027307 (rank : 11)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

PALB2_HUMAN
NC score	0.026015 (rank : 12)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

CT2NL_MOUSE
NC score	0.025501 (rank : 13)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	902	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

WWP1_HUMAN
NC score	0.024995 (rank : 14)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	262	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

CT2NL_HUMAN
NC score	0.024870 (rank : 15)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	1059	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

WWP1_MOUSE
NC score	0.024248 (rank : 16)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

ZN318_MOUSE
NC score	0.023811 (rank : 17)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	642	Shared Neighborhood Hits	10
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

UBP31_HUMAN
NC score	0.023635 (rank : 18)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

PML_MOUSE
NC score	0.023060 (rank : 19)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

DIAP3_MOUSE
NC score	0.021270 (rank : 20)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	221	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

BRCA2_HUMAN
NC score	0.020352 (rank : 21)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	202	Shared Neighborhood Hits	4
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

PDZK4_HUMAN
NC score	0.019216 (rank : 22)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

TPR_HUMAN
NC score	0.018430 (rank : 23)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	1921	Shared Neighborhood Hits	15
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

MMAA_HUMAN
NC score	0.017924 (rank : 24)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IVH4	Gene names	MMAA
Domain Architecture
Description	Methylmalonic aciduria type A protein, mitochondrial precursor.

EP15_HUMAN
NC score	0.015498 (rank : 25)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	1021	Shared Neighborhood Hits	11
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

DPOLZ_HUMAN
NC score	0.014739 (rank : 26)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DCP1A_MOUSE
NC score	0.014671 (rank : 27)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

CSPG2_HUMAN
NC score	0.014640 (rank : 28)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	681	Shared Neighborhood Hits	5
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

OPTN_MOUSE
NC score	0.014477 (rank : 29)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	1120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

DNMT1_MOUSE
NC score	0.013391 (rank : 30)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

PPRB_HUMAN
NC score	0.013309 (rank : 31)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	311	Shared Neighborhood Hits	4
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

STAM2_MOUSE
NC score	0.011492 (rank : 32)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

IWS1_HUMAN
NC score	0.010993 (rank : 33)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	1241	Shared Neighborhood Hits	11
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TRHY_HUMAN
NC score	0.010819 (rank : 34)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	1385	Shared Neighborhood Hits	15
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TCPA2_MOUSE
NC score	0.010745 (rank : 35)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPA1_MOUSE
NC score	0.010722 (rank : 36)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

SYCP1_HUMAN
NC score	0.010069 (rank : 37)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	1313	Shared Neighborhood Hits	13
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

FGD3_HUMAN
NC score	0.009609 (rank : 38)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	249	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

ASPP2_HUMAN
NC score	0.008720 (rank : 39)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	1156	Shared Neighborhood Hits	12
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MYH3_HUMAN
NC score	0.008172 (rank : 40)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	1660	Shared Neighborhood Hits	14
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

LRP1_HUMAN
NC score	0.004106 (rank : 41)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	617	Shared Neighborhood Hits	4
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

ZN514_HUMAN
NC score	0.003607 (rank : 42)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	738	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K75	Gene names	ZNF514
Domain Architecture
Description	Zinc finger protein 514.