Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : MLH1_MOUSE

For an explanation of this page, click here

MLH1_MOUSE
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MLH1_HUMAN
θ value	0 (rank : 1)	NC score	0.992120 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

MLH1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

PMS2_HUMAN
θ value	6.15952e-41 (rank : 3)	NC score	0.740578 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS2_MOUSE
θ value	6.17384e-33 (rank : 4)	NC score	0.735128 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS1_HUMAN
θ value	1.85889e-29 (rank : 5)	NC score	0.674125 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

MLH3_HUMAN
θ value	1.29031e-22 (rank : 6)	NC score	0.644750 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

NFH_MOUSE
θ value	0.0193708 (rank : 7)	NC score	0.016135 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	2247	Shared Neighborhood Hits	11
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RAD50_MOUSE
θ value	0.0563607 (rank : 8)	NC score	0.020881 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	1366	Shared Neighborhood Hits	8
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

MKRN2_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.047123 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.045442 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

IWS1_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.020055 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	1258	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

GON4L_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.026932 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	555	Shared Neighborhood Hits	5
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LPIN2_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.031634 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

SYCP2_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.038136 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	230	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

NCOA6_MOUSE
θ value	1.38821 (rank : 15)	NC score	0.020387 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	1076	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CCD21_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.010025 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	1228	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCM2_MOUSE
θ value	2.36792 (rank : 17)	NC score	0.048466 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2Y9	Gene names	Ccm2, Osm
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations protein 2 homolog) (Osmosensing scaffold for MEKK3).

PRRT3_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.024521 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PO121_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.019959 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RRBP1_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.008390 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	1650	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ABCAD_MOUSE
θ value	6.88961 (rank : 21)	NC score	0.006211 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

BIRC6_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.012835 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

SPT6H_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.014681 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

TP53B_MOUSE
θ value	6.88961 (rank : 24)	NC score	0.016372 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	644	Shared Neighborhood Hits	7
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

IF4G3_MOUSE
θ value	8.99809 (rank : 25)	NC score	0.012642 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

Hits sorted by NC score

MLH1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

MLH1_HUMAN
NC score	0.992120 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

PMS2_HUMAN
NC score	0.740578 (rank : 3)	θ value	6.15952e-41 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS2_MOUSE
NC score	0.735128 (rank : 4)	θ value	6.17384e-33 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS1_HUMAN
NC score	0.674125 (rank : 5)	θ value	1.85889e-29 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

MLH3_HUMAN
NC score	0.644750 (rank : 6)	θ value	1.29031e-22 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

CCM2_MOUSE
NC score	0.048466 (rank : 7)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2Y9	Gene names	Ccm2, Osm
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations protein 2 homolog) (Osmosensing scaffold for MEKK3).

MKRN2_HUMAN
NC score	0.047123 (rank : 8)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
NC score	0.045442 (rank : 9)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

SYCP2_HUMAN
NC score	0.038136 (rank : 10)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	230	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

LPIN2_HUMAN
NC score	0.031634 (rank : 11)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

GON4L_HUMAN
NC score	0.026932 (rank : 12)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	555	Shared Neighborhood Hits	5
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

PRRT3_MOUSE
NC score	0.024521 (rank : 13)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RAD50_MOUSE
NC score	0.020881 (rank : 14)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	1366	Shared Neighborhood Hits	8
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

NCOA6_MOUSE
NC score	0.020387 (rank : 15)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	1076	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

IWS1_MOUSE
NC score	0.020055 (rank : 16)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	1258	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PO121_HUMAN
NC score	0.019959 (rank : 17)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

TP53B_MOUSE
NC score	0.016372 (rank : 18)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	644	Shared Neighborhood Hits	7
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

NFH_MOUSE
NC score	0.016135 (rank : 19)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	2247	Shared Neighborhood Hits	11
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SPT6H_HUMAN
NC score	0.014681 (rank : 20)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

BIRC6_HUMAN
NC score	0.012835 (rank : 21)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

IF4G3_MOUSE
NC score	0.012642 (rank : 22)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

CCD21_HUMAN
NC score	0.010025 (rank : 23)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	1228	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

RRBP1_MOUSE
NC score	0.008390 (rank : 24)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	1650	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ABCAD_MOUSE
NC score	0.006211 (rank : 25)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.