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Network neighborhood for query Sequence : THEX1_HUMAN

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THEX1_HUMAN
SwissProt Accessions	Q8IV48, Q9NSX3	Gene names	THEX1, 3'EXO, ERI1
Domain Architecture
Description	3' histone mRNA exonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3' end-specific exoribonuclease) (Protein 3'hExo) (HEXO).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

THEX1_HUMAN
θ value	2.32313e-181 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IV48, Q9NSX3	Gene names	THEX1, 3'EXO, ERI1
Domain Architecture
Description	3' histone mRNA exonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3' end-specific exoribonuclease) (Protein 3'hExo) (HEXO).

THEX1_MOUSE
θ value	5.21151e-157 (rank : 2)	NC score	0.995939 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TMF2, Q3TA98, Q80UN4, Q8BWR6, Q9CQ63	Gene names	Thex1, 3'exo, Eri1
Domain Architecture
Description	3' histone mRNA exonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog).

PCTK2_HUMAN
θ value	0.47712 (rank : 3)	NC score	0.011483 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	837	Shared Neighborhood Hits	3
SwissProt Accessions	Q00537, Q8NEB8	Gene names	PCTK2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

PCTK2_MOUSE
θ value	1.06291 (rank : 4)	NC score	0.010761 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	836	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0D0	Gene names	Pctk2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

IQEC1_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.024532 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

CP17A_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.012903 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	P05093, Q5TZV7	Gene names	CYP17A1, CYP17, S17AH
Domain Architecture
Description	Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17) (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase).

IQEC1_MOUSE
θ value	6.88961 (rank : 7)	NC score	0.021181 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

KIF2C_HUMAN
θ value	8.99809 (rank : 8)	NC score	0.005741 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

Hits sorted by NC score

THEX1_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.32313e-181 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IV48, Q9NSX3	Gene names	THEX1, 3'EXO, ERI1
Domain Architecture
Description	3' histone mRNA exonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3' end-specific exoribonuclease) (Protein 3'hExo) (HEXO).

THEX1_MOUSE
NC score	0.995939 (rank : 2)	θ value	5.21151e-157 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TMF2, Q3TA98, Q80UN4, Q8BWR6, Q9CQ63	Gene names	Thex1, 3'exo, Eri1
Domain Architecture
Description	3' histone mRNA exonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog).

IQEC1_HUMAN
NC score	0.024532 (rank : 3)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
NC score	0.021181 (rank : 4)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

CP17A_HUMAN
NC score	0.012903 (rank : 5)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	P05093, Q5TZV7	Gene names	CYP17A1, CYP17, S17AH
Domain Architecture
Description	Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17) (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase).

PCTK2_HUMAN
NC score	0.011483 (rank : 6)	θ value	0.47712 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	837	Shared Neighborhood Hits	3
SwissProt Accessions	Q00537, Q8NEB8	Gene names	PCTK2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

PCTK2_MOUSE
NC score	0.010761 (rank : 7)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	836	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0D0	Gene names	Pctk2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

KIF2C_HUMAN
NC score	0.005741 (rank : 8)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).