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Network neighborhood for query Sequence : IER2_MOUSE

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IER2_MOUSE
SwissProt Accessions	P17950, Q64251, Q8BME8, Q99M25	Gene names	Ier2
Domain Architecture
Description	Immediate early response gene 2 protein (T-lymphocyte-activated protein) (Cycloheximide-induced gene protein) (CHX1) (Growth factor- inducible immediate early protein) (Proline-rich-induced protein 92) (Pip92).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IER2_MOUSE
θ value	5.86991e-92 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P17950, Q64251, Q8BME8, Q99M25	Gene names	Ier2
Domain Architecture
Description	Immediate early response gene 2 protein (T-lymphocyte-activated protein) (Cycloheximide-induced gene protein) (CHX1) (Growth factor- inducible immediate early protein) (Proline-rich-induced protein 92) (Pip92).

IER2_HUMAN
θ value	6.11685e-65 (rank : 2)	NC score	0.978106 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

IER5_MOUSE
θ value	5.62301e-10 (rank : 3)	NC score	0.577807 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IER5_HUMAN
θ value	9.59137e-10 (rank : 4)	NC score	0.600058 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IQEC1_HUMAN
θ value	4.03905 (rank : 5)	NC score	0.016374 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

MTR1L_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.004937 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	1180	Shared Neighborhood Hits	2
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NCOR1_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.020178 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	577	Shared Neighborhood Hits	2
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

JIP1_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.025451 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

OFD1_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.011654 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	753	Shared Neighborhood Hits	2
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

JIP1_MOUSE
θ value	8.99809 (rank : 10)	NC score	0.024109 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

Hits sorted by NC score

IER2_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.86991e-92 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P17950, Q64251, Q8BME8, Q99M25	Gene names	Ier2
Domain Architecture
Description	Immediate early response gene 2 protein (T-lymphocyte-activated protein) (Cycloheximide-induced gene protein) (CHX1) (Growth factor- inducible immediate early protein) (Proline-rich-induced protein 92) (Pip92).

IER2_HUMAN
NC score	0.978106 (rank : 2)	θ value	6.11685e-65 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

IER5_HUMAN
NC score	0.600058 (rank : 3)	θ value	9.59137e-10 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IER5_MOUSE
NC score	0.577807 (rank : 4)	θ value	5.62301e-10 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

JIP1_HUMAN
NC score	0.025451 (rank : 5)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
NC score	0.024109 (rank : 6)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

NCOR1_HUMAN
NC score	0.020178 (rank : 7)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	577	Shared Neighborhood Hits	2
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

IQEC1_HUMAN
NC score	0.016374 (rank : 8)	θ value	4.03905 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

OFD1_HUMAN
NC score	0.011654 (rank : 9)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	753	Shared Neighborhood Hits	2
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

MTR1L_HUMAN
NC score	0.004937 (rank : 10)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	1180	Shared Neighborhood Hits	2
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).