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Network neighborhood for query Sequence : HLF_HUMAN

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HLF_HUMAN
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HLF_MOUSE
θ value	5.41814e-138 (rank : 1)	NC score	0.997045 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

HLF_HUMAN
θ value	8.09639e-134 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.

TEF_HUMAN
θ value	1.96316e-71 (rank : 3)	NC score	0.940672 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	70	Shared Neighborhood Hits	22
SwissProt Accessions	Q10587, Q15729, Q7Z3J7, Q8IU94, Q96TG4	Gene names	TEF
Domain Architecture
Description	Thyrotroph embryonic factor.

TEF_MOUSE
θ value	4.83544e-70 (rank : 4)	NC score	0.940442 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JLC6, Q3U426, Q3UGF4, Q3UM49, Q3URC8, Q6QHT6, Q8C6I0, Q8VD02	Gene names	Tef
Domain Architecture	No domain graphic available
Description	Thyrotroph embryonic factor.

DBP_HUMAN
θ value	9.16162e-53 (rank : 5)	NC score	0.913407 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	136	Shared Neighborhood Hits	25
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

DBP_MOUSE
θ value	3.48141e-52 (rank : 6)	NC score	0.914033 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	137	Shared Neighborhood Hits	24
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

BATF_MOUSE
θ value	4.1701e-05 (rank : 7)	NC score	0.390179 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	100	Shared Neighborhood Hits	20
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

CEBPG_HUMAN
θ value	0.000121331 (rank : 8)	NC score	0.386253 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	P53567, Q5U052	Gene names	CEBPG
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma).

CEBPB_HUMAN
θ value	0.00020696 (rank : 9)	NC score	0.344665 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	P17676, Q96IH2, Q9H4Z5	Gene names	CEBPB, TCF5
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).

CEBPG_MOUSE
θ value	0.000602161 (rank : 10)	NC score	0.392181 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	P53568	Gene names	Cebpg
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-binding protein) (GPE1-BP).

CEBPB_MOUSE
θ value	0.00102713 (rank : 11)	NC score	0.338175 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	P28033	Gene names	Cebpb
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Interleukin-6- dependent-binding protein) (IL-6DBP) (Liver-enriched transcriptional activator) (LAP) (AGP/EBP).

BATF_HUMAN
θ value	0.00228821 (rank : 12)	NC score	0.381731 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

CEBPA_HUMAN
θ value	0.0148317 (rank : 13)	NC score	0.291047 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	22
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CEBPA_MOUSE
θ value	0.0148317 (rank : 14)	NC score	0.292233 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

MTSS1_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.099359 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	592	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CEBPE_HUMAN
θ value	0.0330416 (rank : 16)	NC score	0.246624 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	236	Shared Neighborhood Hits	23
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

PSL1_HUMAN
θ value	0.0431538 (rank : 17)	NC score	0.067078 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	650	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

CEBPD_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.286814 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	135	Shared Neighborhood Hits	20
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

CEBPD_MOUSE
θ value	0.0563607 (rank : 19)	NC score	0.283756 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

CEBPE_MOUSE
θ value	0.0736092 (rank : 20)	NC score	0.240015 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PZD9	Gene names	Cebpe
Domain Architecture	No domain graphic available
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

SON_HUMAN
θ value	0.0961366 (rank : 21)	NC score	0.041511 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	1568	Shared Neighborhood Hits	33
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

FETUB_HUMAN
θ value	0.125558 (rank : 22)	NC score	0.076818 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM5, Q1RMZ0, Q6DK58, Q6GRB6, Q9Y6Z0	Gene names	FETUB
Domain Architecture
Description	Fetuin-B precursor (Gugu) (IRL685) (16G2).

MTSS1_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.084852 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	504	Shared Neighborhood Hits	19
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

BTBD7_MOUSE
θ value	0.279714 (rank : 24)	NC score	0.049336 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

DDEF2_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.027421 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	599	Shared Neighborhood Hits	16
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PELP1_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.051603 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	709	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SET1A_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.044153 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	690	Shared Neighborhood Hits	16
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

PACN3_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.066008 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	380	Shared Neighborhood Hits	10
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

DAXX_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.044460 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

EPAS1_MOUSE
θ value	0.813845 (rank : 30)	NC score	0.025818 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

UB7I3_MOUSE
θ value	0.813845 (rank : 31)	NC score	0.049787 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

NCOR2_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.030854 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	790	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PACN3_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.061392 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	385	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

RM49_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.067159 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q13405	Gene names	MRPL49, C11orf4, NOF1
Domain Architecture
Description	Mitochondrial 39S ribosomal protein L49 (L49mt) (MRP-L49) (Protein NOF1) (Neighbor of FAU) (NOF).

MLL3_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.034640 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	1399	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NPHP4_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.035859 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	P59240	Gene names	Nphp4
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

RAPH1_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.032961 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	593	Shared Neighborhood Hits	18
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RM49_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.060589 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQ40, Q3UC21, Q8C5R0, Q8C7P3	Gene names	Mrpl49
Domain Architecture
Description	Mitochondrial 39S ribosomal protein L49 (L49mt) (MRP-L49).

THSD1_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.027351 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

UB7I3_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.043090 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

ATN1_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.038537 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	676	Shared Neighborhood Hits	20
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CAR10_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.017936 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	569	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

DIAP1_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.026741 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	784	Shared Neighborhood Hits	18
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.022606 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	839	Shared Neighborhood Hits	15
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DLP1_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.019313 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q33DR3, Q3USU6, Q9D3K7	Gene names	Pdss2, Dlp1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Solanesyl-diphosphate synthase subunit 2).

GGT1_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.020735 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P19440, Q08247, Q14404, Q8TBS1, Q9UMK1	Gene names	GGT1, GGT
Domain Architecture
Description	Gamma-glutamyltranspeptidase 1 precursor (EC 2.3.2.2) (Gamma- glutamyltransferase 1) (GGT 1) (CD224 antigen) [Contains: Gamma- glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain].

IRAK3_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.003728 (rank : 91)
Query Neighborhood Hits	75	Target Neighborhood Hits	628	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

RGS3_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.016510 (rank : 80)
Query Neighborhood Hits	75	Target Neighborhood Hits	1375	Shared Neighborhood Hits	31
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TEX14_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.007559 (rank : 86)
Query Neighborhood Hits	75	Target Neighborhood Hits	1333	Shared Neighborhood Hits	7
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CI093_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.006131 (rank : 89)
Query Neighborhood Hits	75	Target Neighborhood Hits	1088	Shared Neighborhood Hits	11
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

GOPC_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.017629 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	377	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

HIC2_MOUSE
θ value	5.27518 (rank : 52)	NC score	-0.001056 (rank : 94)
Query Neighborhood Hits	75	Target Neighborhood Hits	821	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).

IF4G1_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.019529 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	347	Shared Neighborhood Hits	12
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MAGE1_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.023457 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	1389	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SYN3_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.013251 (rank : 83)
Query Neighborhood Hits	75	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TAF4_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.030941 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	687	Shared Neighborhood Hits	20
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TNFL6_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.016748 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P48023, Q9BZP9	Gene names	FASLG, APT1LG1, FASL, TNFSF6
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD178 antigen) (CD95L protein) (Apoptosis antigen ligand) (APTL) [Contains: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form].

CNTRB_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.006395 (rank : 87)
Query Neighborhood Hits	75	Target Neighborhood Hits	1029	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

EP300_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.015067 (rank : 82)
Query Neighborhood Hits	75	Target Neighborhood Hits	821	Shared Neighborhood Hits	19
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GGTL4_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.021417 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q14390	Gene names	GGTL4
Domain Architecture
Description	Gamma-glutamyltransferase-like protein 4.

GR65_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.020003 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

JADE2_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.015216 (rank : 81)
Query Neighborhood Hits	75	Target Neighborhood Hits	560	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LATS1_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.000359 (rank : 93)
Query Neighborhood Hits	75	Target Neighborhood Hits	1027	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

LIMA1_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.009666 (rank : 84)
Query Neighborhood Hits	75	Target Neighborhood Hits	298	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

MADCA_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.027122 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	221	Shared Neighborhood Hits	12
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MLL2_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.028256 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	1788	Shared Neighborhood Hits	32
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SPT5H_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.021146 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	436	Shared Neighborhood Hits	18
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.021204 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	437	Shared Neighborhood Hits	18
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

VASN_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.005575 (rank : 90)
Query Neighborhood Hits	75	Target Neighborhood Hits	449	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

FOSL2_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.121634 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	P15408	Gene names	FOSL2, FRA2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

ITSN1_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.006280 (rank : 88)
Query Neighborhood Hits	75	Target Neighborhood Hits	1669	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MILK2_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.007982 (rank : 85)
Query Neighborhood Hits	75	Target Neighborhood Hits	457	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MLL3_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.027836 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	1644	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SALL3_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.000676 (rank : 92)
Query Neighborhood Hits	75	Target Neighborhood Hits	1066	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SF01_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.020834 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

ATF2_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.062777 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	402	Shared Neighborhood Hits	15
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.060859 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	397	Shared Neighborhood Hits	15
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATF3_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.095816 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF3_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.097294 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

ATF4_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.081785 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	P18848, Q9UH31	Gene names	ATF4
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-4 (Activating transcription factor 4) (DNA-binding protein TAXREB67) (Cyclic AMP response element-binding protein 2) (CREB2).

ATF4_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.090433 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

ATF5_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.088249 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

ATF7_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.077070 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	333	Shared Neighborhood Hits	21
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.075823 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	286	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

CREB5_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.062489 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

DDIT3_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.121189 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

DDIT3_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.124291 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	P35639, Q91YW9	Gene names	Ddit3, Chop, Gadd153
Domain Architecture	No domain graphic available
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

FOSB_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.109825 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	141	Shared Neighborhood Hits	20
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

FOSB_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.106935 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

FOSL2_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.113849 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P47930	Gene names	Fosl2, Fra-2, Fra2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

FOS_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.093385 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	P01100, P18849	Gene names	FOS, G0S7
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7).

FOS_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.094126 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

XBP1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.087559 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

XBP1_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.099519 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

Hits sorted by NC score

HLF_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.09639e-134 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.

HLF_MOUSE
NC score	0.997045 (rank : 2)	θ value	5.41814e-138 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

TEF_HUMAN
NC score	0.940672 (rank : 3)	θ value	1.96316e-71 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	70	Shared Neighborhood Hits	22
SwissProt Accessions	Q10587, Q15729, Q7Z3J7, Q8IU94, Q96TG4	Gene names	TEF
Domain Architecture
Description	Thyrotroph embryonic factor.

TEF_MOUSE
NC score	0.940442 (rank : 4)	θ value	4.83544e-70 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JLC6, Q3U426, Q3UGF4, Q3UM49, Q3URC8, Q6QHT6, Q8C6I0, Q8VD02	Gene names	Tef
Domain Architecture	No domain graphic available
Description	Thyrotroph embryonic factor.

DBP_MOUSE
NC score	0.914033 (rank : 5)	θ value	3.48141e-52 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	137	Shared Neighborhood Hits	24
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

DBP_HUMAN
NC score	0.913407 (rank : 6)	θ value	9.16162e-53 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	136	Shared Neighborhood Hits	25
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

CEBPG_MOUSE
NC score	0.392181 (rank : 7)	θ value	0.000602161 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	P53568	Gene names	Cebpg
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-binding protein) (GPE1-BP).

BATF_MOUSE
NC score	0.390179 (rank : 8)	θ value	4.1701e-05 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	100	Shared Neighborhood Hits	20
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

CEBPG_HUMAN
NC score	0.386253 (rank : 9)	θ value	0.000121331 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	P53567, Q5U052	Gene names	CEBPG
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma).

BATF_HUMAN
NC score	0.381731 (rank : 10)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

CEBPB_HUMAN
NC score	0.344665 (rank : 11)	θ value	0.00020696 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	P17676, Q96IH2, Q9H4Z5	Gene names	CEBPB, TCF5
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).

CEBPB_MOUSE
NC score	0.338175 (rank : 12)	θ value	0.00102713 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	P28033	Gene names	Cebpb
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Interleukin-6- dependent-binding protein) (IL-6DBP) (Liver-enriched transcriptional activator) (LAP) (AGP/EBP).

CEBPA_MOUSE
NC score	0.292233 (rank : 13)	θ value	0.0148317 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CEBPA_HUMAN
NC score	0.291047 (rank : 14)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	22
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CEBPD_HUMAN
NC score	0.286814 (rank : 15)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	135	Shared Neighborhood Hits	20
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

CEBPD_MOUSE
NC score	0.283756 (rank : 16)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

CEBPE_HUMAN
NC score	0.246624 (rank : 17)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	236	Shared Neighborhood Hits	23
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CEBPE_MOUSE
NC score	0.240015 (rank : 18)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PZD9	Gene names	Cebpe
Domain Architecture	No domain graphic available
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

DDIT3_MOUSE
NC score	0.124291 (rank : 19)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	75	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	P35639, Q91YW9	Gene names	Ddit3, Chop, Gadd153
Domain Architecture	No domain graphic available
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

FOSL2_HUMAN
NC score	0.121634 (rank : 20)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	P15408	Gene names	FOSL2, FRA2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

DDIT3_HUMAN
NC score	0.121189 (rank : 21)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	75	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

FOSL2_MOUSE
NC score	0.113849 (rank : 22)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	75	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P47930	Gene names	Fosl2, Fra-2, Fra2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

FOSB_HUMAN
NC score	0.109825 (rank : 23)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	75	Target Neighborhood Hits	141	Shared Neighborhood Hits	20
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

FOSB_MOUSE
NC score	0.106935 (rank : 24)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	75	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

XBP1_MOUSE
NC score	0.099519 (rank : 25)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

MTSS1_MOUSE
NC score	0.099359 (rank : 26)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	592	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

ATF3_MOUSE
NC score	0.097294 (rank : 27)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

ATF3_HUMAN
NC score	0.095816 (rank : 28)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

FOS_MOUSE
NC score	0.094126 (rank : 29)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	75	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

FOS_HUMAN
NC score	0.093385 (rank : 30)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	75	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	P01100, P18849	Gene names	FOS, G0S7
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7).

ATF4_MOUSE
NC score	0.090433 (rank : 31)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	75	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

ATF5_MOUSE
NC score	0.088249 (rank : 32)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	75	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

XBP1_HUMAN
NC score	0.087559 (rank : 33)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

MTSS1_HUMAN
NC score	0.084852 (rank : 34)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	504	Shared Neighborhood Hits	19
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

ATF4_HUMAN
NC score	0.081785 (rank : 35)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	75	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	P18848, Q9UH31	Gene names	ATF4
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-4 (Activating transcription factor 4) (DNA-binding protein TAXREB67) (Cyclic AMP response element-binding protein 2) (CREB2).

ATF7_HUMAN
NC score	0.077070 (rank : 36)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	75	Target Neighborhood Hits	333	Shared Neighborhood Hits	21
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

FETUB_HUMAN
NC score	0.076818 (rank : 37)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM5, Q1RMZ0, Q6DK58, Q6GRB6, Q9Y6Z0	Gene names	FETUB
Domain Architecture
Description	Fetuin-B precursor (Gugu) (IRL685) (16G2).

ATF7_MOUSE
NC score	0.075823 (rank : 38)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	75	Target Neighborhood Hits	286	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

RM49_HUMAN
NC score	0.067159 (rank : 39)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q13405	Gene names	MRPL49, C11orf4, NOF1
Domain Architecture
Description	Mitochondrial 39S ribosomal protein L49 (L49mt) (MRP-L49) (Protein NOF1) (Neighbor of FAU) (NOF).

PSL1_HUMAN
NC score	0.067078 (rank : 40)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	650	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PACN3_MOUSE
NC score	0.066008 (rank : 41)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	380	Shared Neighborhood Hits	10
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

ATF2_HUMAN
NC score	0.062777 (rank : 42)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	402	Shared Neighborhood Hits	15
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

CREB5_HUMAN
NC score	0.062489 (rank : 43)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	75	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

PACN3_HUMAN
NC score	0.061392 (rank : 44)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	385	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

ATF2_MOUSE
NC score	0.060859 (rank : 45)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	397	Shared Neighborhood Hits	15
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

RM49_MOUSE
NC score	0.060589 (rank : 46)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQ40, Q3UC21, Q8C5R0, Q8C7P3	Gene names	Mrpl49
Domain Architecture
Description	Mitochondrial 39S ribosomal protein L49 (L49mt) (MRP-L49).

PELP1_MOUSE
NC score	0.051603 (rank : 47)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	709	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

UB7I3_MOUSE
NC score	0.049787 (rank : 48)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

BTBD7_MOUSE
NC score	0.049336 (rank : 49)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

DAXX_HUMAN
NC score	0.044460 (rank : 50)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

SET1A_HUMAN
NC score	0.044153 (rank : 51)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	690	Shared Neighborhood Hits	16
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

UB7I3_HUMAN
NC score	0.043090 (rank : 52)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

SON_HUMAN
NC score	0.041511 (rank : 53)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	1568	Shared Neighborhood Hits	33
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ATN1_HUMAN
NC score	0.038537 (rank : 54)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	676	Shared Neighborhood Hits	20
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

NPHP4_MOUSE
NC score	0.035859 (rank : 55)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	P59240	Gene names	Nphp4
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

MLL3_MOUSE
NC score	0.034640 (rank : 56)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	1399	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RAPH1_HUMAN
NC score	0.032961 (rank : 57)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	593	Shared Neighborhood Hits	18
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

TAF4_HUMAN
NC score	0.030941 (rank : 58)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	687	Shared Neighborhood Hits	20
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

NCOR2_MOUSE
NC score	0.030854 (rank : 59)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	790	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

MLL2_HUMAN
NC score	0.028256 (rank : 60)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	1788	Shared Neighborhood Hits	32
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.027836 (rank : 61)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	1644	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DDEF2_HUMAN
NC score	0.027421 (rank : 62)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	599	Shared Neighborhood Hits	16
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

THSD1_MOUSE
NC score	0.027351 (rank : 63)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

MADCA_HUMAN
NC score	0.027122 (rank : 64)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	221	Shared Neighborhood Hits	12
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

DIAP1_HUMAN
NC score	0.026741 (rank : 65)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	784	Shared Neighborhood Hits	18
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

EPAS1_MOUSE
NC score	0.025818 (rank : 66)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

MAGE1_HUMAN
NC score	0.023457 (rank : 67)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	1389	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DIAP1_MOUSE
NC score	0.022606 (rank : 68)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	839	Shared Neighborhood Hits	15
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

GGTL4_HUMAN
NC score	0.021417 (rank : 69)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q14390	Gene names	GGTL4
Domain Architecture
Description	Gamma-glutamyltransferase-like protein 4.

SPT5H_MOUSE
NC score	0.021204 (rank : 70)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	437	Shared Neighborhood Hits	18
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.021146 (rank : 71)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	436	Shared Neighborhood Hits	18
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SF01_HUMAN
NC score	0.020834 (rank : 72)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

GGT1_HUMAN
NC score	0.020735 (rank : 73)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P19440, Q08247, Q14404, Q8TBS1, Q9UMK1	Gene names	GGT1, GGT
Domain Architecture
Description	Gamma-glutamyltranspeptidase 1 precursor (EC 2.3.2.2) (Gamma- glutamyltransferase 1) (GGT 1) (CD224 antigen) [Contains: Gamma- glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain].

GR65_HUMAN
NC score	0.020003 (rank : 74)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

IF4G1_HUMAN
NC score	0.019529 (rank : 75)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	347	Shared Neighborhood Hits	12
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

DLP1_MOUSE
NC score	0.019313 (rank : 76)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q33DR3, Q3USU6, Q9D3K7	Gene names	Pdss2, Dlp1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Solanesyl-diphosphate synthase subunit 2).

CAR10_HUMAN
NC score	0.017936 (rank : 77)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	569	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

GOPC_HUMAN
NC score	0.017629 (rank : 78)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	377	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

TNFL6_HUMAN
NC score	0.016748 (rank : 79)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P48023, Q9BZP9	Gene names	FASLG, APT1LG1, FASL, TNFSF6
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD178 antigen) (CD95L protein) (Apoptosis antigen ligand) (APTL) [Contains: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form].

RGS3_HUMAN
NC score	0.016510 (rank : 80)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	1375	Shared Neighborhood Hits	31
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

JADE2_MOUSE
NC score	0.015216 (rank : 81)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	560	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

EP300_HUMAN
NC score	0.015067 (rank : 82)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	821	Shared Neighborhood Hits	19
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

SYN3_HUMAN
NC score	0.013251 (rank : 83)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

LIMA1_MOUSE
NC score	0.009666 (rank : 84)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	298	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

MILK2_HUMAN
NC score	0.007982 (rank : 85)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	457	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

TEX14_MOUSE
NC score	0.007559 (rank : 86)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	1333	Shared Neighborhood Hits	7
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CNTRB_MOUSE
NC score	0.006395 (rank : 87)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	1029	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

ITSN1_MOUSE
NC score	0.006280 (rank : 88)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	1669	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CI093_HUMAN
NC score	0.006131 (rank : 89)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	1088	Shared Neighborhood Hits	11
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

VASN_HUMAN
NC score	0.005575 (rank : 90)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	449	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

IRAK3_MOUSE
NC score	0.003728 (rank : 91)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	628	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

SALL3_HUMAN
NC score	0.000676 (rank : 92)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	1066	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

LATS1_MOUSE
NC score	0.000359 (rank : 93)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	1027	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

HIC2_MOUSE
NC score	-0.001056 (rank : 94)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	821	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).