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Network neighborhood for query Sequence : MGRN1_HUMAN

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MGRN1_HUMAN
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MGRN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	192	Target Neighborhood Hits	192	Shared Neighborhood Hits	192
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	0 (rank : 2)	NC score	0.976155 (rank : 2)
Query Neighborhood Hits	192	Target Neighborhood Hits	149	Shared Neighborhood Hits	130
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RNF26_HUMAN
θ value	1.53129e-07 (rank : 3)	NC score	0.501518 (rank : 3)
Query Neighborhood Hits	192	Target Neighborhood Hits	95	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

CGRF1_HUMAN
θ value	8.40245e-06 (rank : 4)	NC score	0.377832 (rank : 6)
Query Neighborhood Hits	192	Target Neighborhood Hits	51	Shared Neighborhood Hits	40
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

NEURL_MOUSE
θ value	8.40245e-06 (rank : 5)	NC score	0.378116 (rank : 5)
Query Neighborhood Hits	192	Target Neighborhood Hits	106	Shared Neighborhood Hits	68
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NEUL1_HUMAN
θ value	1.87187e-05 (rank : 6)	NC score	0.371676 (rank : 7)
Query Neighborhood Hits	192	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

CGRF1_MOUSE
θ value	3.19293e-05 (rank : 7)	NC score	0.383772 (rank : 4)
Query Neighborhood Hits	192	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

RFFL_MOUSE
θ value	0.000270298 (rank : 8)	NC score	0.342689 (rank : 10)
Query Neighborhood Hits	192	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

LRSM1_HUMAN
θ value	0.000461057 (rank : 9)	NC score	0.147487 (rank : 71)
Query Neighborhood Hits	192	Target Neighborhood Hits	1078	Shared Neighborhood Hits	71
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LRSM1_MOUSE
θ value	0.000461057 (rank : 10)	NC score	0.163074 (rank : 60)
Query Neighborhood Hits	192	Target Neighborhood Hits	874	Shared Neighborhood Hits	73
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

TENS1_HUMAN
θ value	0.000602161 (rank : 11)	NC score	0.081173 (rank : 210)
Query Neighborhood Hits	192	Target Neighborhood Hits	400	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

RN141_HUMAN
θ value	0.000786445 (rank : 12)	NC score	0.303702 (rank : 12)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.000786445 (rank : 13)	NC score	0.303625 (rank : 13)
Query Neighborhood Hits	192	Target Neighborhood Hits	200	Shared Neighborhood Hits	88
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RFFL_HUMAN
θ value	0.00102713 (rank : 14)	NC score	0.335368 (rank : 11)
Query Neighborhood Hits	192	Target Neighborhood Hits	175	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RNF34_MOUSE
θ value	0.00102713 (rank : 15)	NC score	0.348925 (rank : 8)
Query Neighborhood Hits	192	Target Neighborhood Hits	160	Shared Neighborhood Hits	76
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
θ value	0.00134147 (rank : 16)	NC score	0.346299 (rank : 9)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	73
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

MAGAA_HUMAN
θ value	0.00175202 (rank : 17)	NC score	0.046763 (rank : 273)
Query Neighborhood Hits	192	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	P43363	Gene names	MAGEA10, MAGE10
Domain Architecture
Description	Melanoma-associated antigen 10 (MAGE-10 antigen).

RN165_HUMAN
θ value	0.00175202 (rank : 18)	NC score	0.241294 (rank : 21)
Query Neighborhood Hits	192	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN133_HUMAN
θ value	0.00298849 (rank : 19)	NC score	0.201842 (rank : 32)
Query Neighborhood Hits	192	Target Neighborhood Hits	108	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

TRI26_MOUSE
θ value	0.00298849 (rank : 20)	NC score	0.182364 (rank : 49)
Query Neighborhood Hits	192	Target Neighborhood Hits	339	Shared Neighborhood Hits	113
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI47_HUMAN
θ value	0.00298849 (rank : 21)	NC score	0.193130 (rank : 40)
Query Neighborhood Hits	192	Target Neighborhood Hits	286	Shared Neighborhood Hits	91
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

BIRC2_HUMAN
θ value	0.00509761 (rank : 22)	NC score	0.257502 (rank : 17)
Query Neighborhood Hits	192	Target Neighborhood Hits	142	Shared Neighborhood Hits	74
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

TRI65_MOUSE
θ value	0.00509761 (rank : 23)	NC score	0.202934 (rank : 31)
Query Neighborhood Hits	192	Target Neighborhood Hits	340	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

BIRC3_HUMAN
θ value	0.00665767 (rank : 24)	NC score	0.263975 (rank : 16)
Query Neighborhood Hits	192	Target Neighborhood Hits	133	Shared Neighborhood Hits	74
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC2_MOUSE
θ value	0.00869519 (rank : 25)	NC score	0.254812 (rank : 19)
Query Neighborhood Hits	192	Target Neighborhood Hits	137	Shared Neighborhood Hits	68
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_MOUSE
θ value	0.00869519 (rank : 26)	NC score	0.257140 (rank : 18)
Query Neighborhood Hits	192	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

TRI47_MOUSE
θ value	0.00869519 (rank : 27)	NC score	0.187543 (rank : 44)
Query Neighborhood Hits	192	Target Neighborhood Hits	295	Shared Neighborhood Hits	91
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

MIB1_HUMAN
θ value	0.0113563 (rank : 28)	NC score	0.119312 (rank : 111)
Query Neighborhood Hits	192	Target Neighborhood Hits	470	Shared Neighborhood Hits	77
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.0113563 (rank : 29)	NC score	0.120346 (rank : 109)
Query Neighborhood Hits	192	Target Neighborhood Hits	471	Shared Neighborhood Hits	77
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

TRI30_MOUSE
θ value	0.0148317 (rank : 30)	NC score	0.138070 (rank : 78)
Query Neighborhood Hits	192	Target Neighborhood Hits	434	Shared Neighborhood Hits	88
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI26_HUMAN
θ value	0.0193708 (rank : 31)	NC score	0.175682 (rank : 53)
Query Neighborhood Hits	192	Target Neighborhood Hits	335	Shared Neighborhood Hits	112
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

BIRC7_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.295514 (rank : 14)
Query Neighborhood Hits	192	Target Neighborhood Hits	185	Shared Neighborhood Hits	94
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

DNPEP_MOUSE
θ value	0.0252991 (rank : 33)	NC score	0.100591 (rank : 150)
Query Neighborhood Hits	192	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2W0	Gene names	Dnpep
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

DIDO1_HUMAN
θ value	0.0330416 (rank : 34)	NC score	0.050734 (rank : 269)
Query Neighborhood Hits	192	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

LNX1_MOUSE
θ value	0.0330416 (rank : 35)	NC score	0.121567 (rank : 105)
Query Neighborhood Hits	192	Target Neighborhood Hits	377	Shared Neighborhood Hits	91
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

TTBK1_HUMAN
θ value	0.0330416 (rank : 36)	NC score	0.021366 (rank : 291)
Query Neighborhood Hits	192	Target Neighborhood Hits	1058	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

AMFR2_HUMAN
θ value	0.0431538 (rank : 37)	NC score	0.204241 (rank : 30)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	0.0431538 (rank : 38)	NC score	0.210557 (rank : 25)
Query Neighborhood Hits	192	Target Neighborhood Hits	208	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

RKHD1_HUMAN
θ value	0.0431538 (rank : 39)	NC score	0.285337 (rank : 15)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

SH3K1_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.044206 (rank : 275)
Query Neighborhood Hits	192	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

GOLI_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.181275 (rank : 51)
Query Neighborhood Hits	192	Target Neighborhood Hits	137	Shared Neighborhood Hits	44
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	0.0736092 (rank : 42)	NC score	0.178887 (rank : 52)
Query Neighborhood Hits	192	Target Neighborhood Hits	134	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

MYLIP_HUMAN
θ value	0.0736092 (rank : 43)	NC score	0.160392 (rank : 61)
Query Neighborhood Hits	192	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CB017_HUMAN
θ value	0.0961366 (rank : 44)	NC score	0.088160 (rank : 189)
Query Neighborhood Hits	192	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

CBL_HUMAN
θ value	0.0961366 (rank : 45)	NC score	0.208327 (rank : 26)
Query Neighborhood Hits	192	Target Neighborhood Hits	353	Shared Neighborhood Hits	108
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.0961366 (rank : 46)	NC score	0.206485 (rank : 29)
Query Neighborhood Hits	192	Target Neighborhood Hits	426	Shared Neighborhood Hits	112
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

MDM2_MOUSE
θ value	0.0961366 (rank : 47)	NC score	0.168760 (rank : 56)
Query Neighborhood Hits	192	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

MDM4_HUMAN
θ value	0.0961366 (rank : 48)	NC score	0.173758 (rank : 54)
Query Neighborhood Hits	192	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

CHFR_HUMAN
θ value	0.21417 (rank : 49)	NC score	0.207590 (rank : 28)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	98
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

LNX1_HUMAN
θ value	0.21417 (rank : 50)	NC score	0.114099 (rank : 123)
Query Neighborhood Hits	192	Target Neighborhood Hits	379	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MDM2_HUMAN
θ value	0.21417 (rank : 51)	NC score	0.173300 (rank : 55)
Query Neighborhood Hits	192	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MYLIP_MOUSE
θ value	0.21417 (rank : 52)	NC score	0.138087 (rank : 77)
Query Neighborhood Hits	192	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

TRI37_HUMAN
θ value	0.21417 (rank : 53)	NC score	0.163966 (rank : 58)
Query Neighborhood Hits	192	Target Neighborhood Hits	307	Shared Neighborhood Hits	79
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	0.21417 (rank : 54)	NC score	0.163868 (rank : 59)
Query Neighborhood Hits	192	Target Neighborhood Hits	316	Shared Neighborhood Hits	79
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI50_MOUSE
θ value	0.21417 (rank : 55)	NC score	0.147294 (rank : 72)
Query Neighborhood Hits	192	Target Neighborhood Hits	326	Shared Neighborhood Hits	105
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

CBLB_HUMAN
θ value	0.279714 (rank : 56)	NC score	0.199941 (rank : 34)
Query Neighborhood Hits	192	Target Neighborhood Hits	261	Shared Neighborhood Hits	103
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0.279714 (rank : 57)	NC score	0.199830 (rank : 35)
Query Neighborhood Hits	192	Target Neighborhood Hits	277	Shared Neighborhood Hits	104
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

RBBP6_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.086504 (rank : 197)
Query Neighborhood Hits	192	Target Neighborhood Hits	1135	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.095563 (rank : 164)
Query Neighborhood Hits	192	Target Neighborhood Hits	1014	Shared Neighborhood Hits	83
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRIM1_HUMAN
θ value	0.279714 (rank : 60)	NC score	0.135306 (rank : 84)
Query Neighborhood Hits	192	Target Neighborhood Hits	345	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.279714 (rank : 61)	NC score	0.134103 (rank : 89)
Query Neighborhood Hits	192	Target Neighborhood Hits	361	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

UBE4B_HUMAN
θ value	0.279714 (rank : 62)	NC score	0.046581 (rank : 274)
Query Neighborhood Hits	192	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ZC3H5_HUMAN
θ value	0.279714 (rank : 63)	NC score	0.117987 (rank : 114)
Query Neighborhood Hits	192	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

ZC3H5_MOUSE
θ value	0.279714 (rank : 64)	NC score	0.115372 (rank : 119)
Query Neighborhood Hits	192	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

CB017_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.083484 (rank : 205)
Query Neighborhood Hits	192	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NS82, Q3TA48, Q8BSD3, Q8CHY1, Q8R0Q3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17 homolog.

PEX10_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.252886 (rank : 20)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	106
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN168_MOUSE
θ value	0.365318 (rank : 67)	NC score	0.182671 (rank : 48)
Query Neighborhood Hits	192	Target Neighborhood Hits	440	Shared Neighborhood Hits	97
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SH3K1_MOUSE
θ value	0.365318 (rank : 68)	NC score	0.040183 (rank : 277)
Query Neighborhood Hits	192	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

BIRC8_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.236745 (rank : 22)
Query Neighborhood Hits	192	Target Neighborhood Hits	121	Shared Neighborhood Hits	69
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

MLL2_HUMAN
θ value	0.47712 (rank : 70)	NC score	0.033740 (rank : 279)
Query Neighborhood Hits	192	Target Neighborhood Hits	1788	Shared Neighborhood Hits	45
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PML_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.134949 (rank : 85)
Query Neighborhood Hits	192	Target Neighborhood Hits	248	Shared Neighborhood Hits	62
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

SPEG_HUMAN
θ value	0.47712 (rank : 72)	NC score	0.002959 (rank : 322)
Query Neighborhood Hits	192	Target Neighborhood Hits	1762	Shared Neighborhood Hits	19
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRI18_MOUSE
θ value	0.47712 (rank : 73)	NC score	0.134866 (rank : 86)
Query Neighborhood Hits	192	Target Neighborhood Hits	292	Shared Neighborhood Hits	88
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI43_HUMAN
θ value	0.47712 (rank : 74)	NC score	0.128212 (rank : 98)
Query Neighborhood Hits	192	Target Neighborhood Hits	341	Shared Neighborhood Hits	101
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI65_HUMAN
θ value	0.47712 (rank : 75)	NC score	0.183739 (rank : 45)
Query Neighborhood Hits	192	Target Neighborhood Hits	330	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CBLC_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.194570 (rank : 39)
Query Neighborhood Hits	192	Target Neighborhood Hits	173	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CHFR_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.207971 (rank : 27)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN167_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.154536 (rank : 69)
Query Neighborhood Hits	192	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.158275 (rank : 63)
Query Neighborhood Hits	192	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN168_HUMAN
θ value	0.62314 (rank : 80)	NC score	0.195625 (rank : 38)
Query Neighborhood Hits	192	Target Neighborhood Hits	370	Shared Neighborhood Hits	101
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF8_MOUSE
θ value	0.62314 (rank : 81)	NC score	0.199730 (rank : 36)
Query Neighborhood Hits	192	Target Neighborhood Hits	618	Shared Neighborhood Hits	121
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RPGF6_HUMAN
θ value	0.62314 (rank : 82)	NC score	0.026769 (rank : 284)
Query Neighborhood Hits	192	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SMRC2_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.055670 (rank : 257)
Query Neighborhood Hits	192	Target Neighborhood Hits	499	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TRI18_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.129967 (rank : 96)
Query Neighborhood Hits	192	Target Neighborhood Hits	307	Shared Neighborhood Hits	86
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRIM9_MOUSE
θ value	0.62314 (rank : 85)	NC score	0.131444 (rank : 93)
Query Neighborhood Hits	192	Target Neighborhood Hits	274	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

BIRC4_MOUSE
θ value	0.813845 (rank : 86)	NC score	0.200044 (rank : 33)
Query Neighborhood Hits	192	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

RN146_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.183249 (rank : 46)
Query Neighborhood Hits	192	Target Neighborhood Hits	162	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.181403 (rank : 50)
Query Neighborhood Hits	192	Target Neighborhood Hits	161	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RNF13_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.155306 (rank : 66)
Query Neighborhood Hits	192	Target Neighborhood Hits	147	Shared Neighborhood Hits	53
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.154541 (rank : 68)
Query Neighborhood Hits	192	Target Neighborhood Hits	164	Shared Neighborhood Hits	58
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

CM007_MOUSE
θ value	1.06291 (rank : 91)	NC score	0.137465 (rank : 81)
Query Neighborhood Hits	192	Target Neighborhood Hits	416	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DREB_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.028915 (rank : 283)
Query Neighborhood Hits	192	Target Neighborhood Hits	450	Shared Neighborhood Hits	12
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MIB2_MOUSE
θ value	1.06291 (rank : 93)	NC score	0.092932 (rank : 173)
Query Neighborhood Hits	192	Target Neighborhood Hits	409	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

NACAM_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.029637 (rank : 282)
Query Neighborhood Hits	192	Target Neighborhood Hits	1866	Shared Neighborhood Hits	42
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RNF11_HUMAN
θ value	1.06291 (rank : 95)	NC score	0.144084 (rank : 75)
Query Neighborhood Hits	192	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	1.06291 (rank : 96)	NC score	0.143758 (rank : 76)
Query Neighborhood Hits	192	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

SMRC2_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.054156 (rank : 263)
Query Neighborhood Hits	192	Target Neighborhood Hits	487	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ZN179_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.156782 (rank : 65)
Query Neighborhood Hits	192	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

BIRC4_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.197921 (rank : 37)
Query Neighborhood Hits	192	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

CM007_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.124926 (rank : 99)
Query Neighborhood Hits	192	Target Neighborhood Hits	422	Shared Neighborhood Hits	72
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

GFI1_HUMAN
θ value	1.38821 (rank : 101)	NC score	-0.001692 (rank : 325)
Query Neighborhood Hits	192	Target Neighborhood Hits	726	Shared Neighborhood Hits	9
SwissProt Accessions	Q99684, Q8N564	Gene names	GFI1, ZNF163
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

RN125_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.167354 (rank : 57)
Query Neighborhood Hits	192	Target Neighborhood Hits	230	Shared Neighborhood Hits	87
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RNF8_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.189080 (rank : 42)
Query Neighborhood Hits	192	Target Neighborhood Hits	622	Shared Neighborhood Hits	118
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRAF7_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.059442 (rank : 243)
Query Neighborhood Hits	192	Target Neighborhood Hits	482	Shared Neighborhood Hits	81
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRI25_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.156910 (rank : 64)
Query Neighborhood Hits	192	Target Neighborhood Hits	446	Shared Neighborhood Hits	100
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI60_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.124097 (rank : 100)
Query Neighborhood Hits	192	Target Neighborhood Hits	357	Shared Neighborhood Hits	105
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI73_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.155118 (rank : 67)
Query Neighborhood Hits	192	Target Neighborhood Hits	258	Shared Neighborhood Hits	97
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.150586 (rank : 70)
Query Neighborhood Hits	192	Target Neighborhood Hits	249	Shared Neighborhood Hits	94
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM9_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.131152 (rank : 94)
Query Neighborhood Hits	192	Target Neighborhood Hits	294	Shared Neighborhood Hits	64
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

CABIN_HUMAN
θ value	1.81305 (rank : 110)	NC score	0.036465 (rank : 278)
Query Neighborhood Hits	192	Target Neighborhood Hits	490	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

MINT_MOUSE
θ value	1.81305 (rank : 111)	NC score	0.022747 (rank : 287)
Query Neighborhood Hits	192	Target Neighborhood Hits	1514	Shared Neighborhood Hits	29
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFH_HUMAN
θ value	1.81305 (rank : 112)	NC score	0.011646 (rank : 310)
Query Neighborhood Hits	192	Target Neighborhood Hits	1242	Shared Neighborhood Hits	27
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PCLO_MOUSE
θ value	1.81305 (rank : 113)	NC score	0.024244 (rank : 286)
Query Neighborhood Hits	192	Target Neighborhood Hits	2275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PIAS4_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.022356 (rank : 289)
Query Neighborhood Hits	192	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

PML_MOUSE
θ value	1.81305 (rank : 115)	NC score	0.117022 (rank : 115)
Query Neighborhood Hits	192	Target Neighborhood Hits	246	Shared Neighborhood Hits	54
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PRDM2_HUMAN
θ value	1.81305 (rank : 116)	NC score	0.007662 (rank : 321)
Query Neighborhood Hits	192	Target Neighborhood Hits	1135	Shared Neighborhood Hits	20
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PZRN4_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.091783 (rank : 179)
Query Neighborhood Hits	192	Target Neighborhood Hits	438	Shared Neighborhood Hits	97
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RN185_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.217699 (rank : 23)
Query Neighborhood Hits	192	Target Neighborhood Hits	213	Shared Neighborhood Hits	100
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	1.81305 (rank : 119)	NC score	0.214373 (rank : 24)
Query Neighborhood Hits	192	Target Neighborhood Hits	211	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRAF6_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.106237 (rank : 142)
Query Neighborhood Hits	192	Target Neighborhood Hits	267	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	1.81305 (rank : 121)	NC score	0.105930 (rank : 144)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	78
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI50_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.136459 (rank : 82)
Query Neighborhood Hits	192	Target Neighborhood Hits	294	Shared Neighborhood Hits	102
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI59_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.130210 (rank : 95)
Query Neighborhood Hits	192	Target Neighborhood Hits	307	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

ZN313_MOUSE
θ value	1.81305 (rank : 124)	NC score	0.159865 (rank : 62)
Query Neighborhood Hits	192	Target Neighborhood Hits	273	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

CQ050_MOUSE
θ value	2.36792 (rank : 125)	NC score	0.041960 (rank : 276)
Query Neighborhood Hits	192	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C1R3, Q9DAI8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf50 homolog.

MIB2_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.094277 (rank : 168)
Query Neighborhood Hits	192	Target Neighborhood Hits	438	Shared Neighborhood Hits	61
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

NF2L3_MOUSE
θ value	2.36792 (rank : 127)	NC score	0.019535 (rank : 296)
Query Neighborhood Hits	192	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

R113A_HUMAN
θ value	2.36792 (rank : 128)	NC score	0.107670 (rank : 138)
Query Neighborhood Hits	192	Target Neighborhood Hits	177	Shared Neighborhood Hits	63
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RHG06_MOUSE
θ value	2.36792 (rank : 129)	NC score	0.014316 (rank : 305)
Query Neighborhood Hits	192	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RIMS2_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.018999 (rank : 297)
Query Neighborhood Hits	192	Target Neighborhood Hits	376	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RNF24_HUMAN
θ value	2.36792 (rank : 131)	NC score	0.133051 (rank : 91)
Query Neighborhood Hits	192	Target Neighborhood Hits	122	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	2.36792 (rank : 132)	NC score	0.133963 (rank : 90)
Query Neighborhood Hits	192	Target Neighborhood Hits	124	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

SRRM2_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.031481 (rank : 280)
Query Neighborhood Hits	192	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRAF7_MOUSE
θ value	2.36792 (rank : 134)	NC score	0.058035 (rank : 249)
Query Neighborhood Hits	192	Target Neighborhood Hits	470	Shared Neighborhood Hits	79
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI56_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.137645 (rank : 80)
Query Neighborhood Hits	192	Target Neighborhood Hits	339	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

AP2A1_MOUSE
θ value	3.0926 (rank : 136)	NC score	0.012795 (rank : 308)
Query Neighborhood Hits	192	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

MDM4_MOUSE
θ value	3.0926 (rank : 137)	NC score	0.113142 (rank : 128)
Query Neighborhood Hits	192	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MYCL1_MOUSE
θ value	3.0926 (rank : 138)	NC score	0.020427 (rank : 294)
Query Neighborhood Hits	192	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

SMRA3_HUMAN
θ value	3.0926 (rank : 139)	NC score	0.109211 (rank : 135)
Query Neighborhood Hits	192	Target Neighborhood Hits	265	Shared Neighborhood Hits	96
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	3.0926 (rank : 140)	NC score	0.109039 (rank : 136)
Query Neighborhood Hits	192	Target Neighborhood Hits	267	Shared Neighborhood Hits	95
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TLE2_MOUSE
θ value	3.0926 (rank : 141)	NC score	0.009218 (rank : 315)
Query Neighborhood Hits	192	Target Neighborhood Hits	294	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

TRI10_MOUSE
θ value	3.0926 (rank : 142)	NC score	0.110236 (rank : 133)
Query Neighborhood Hits	192	Target Neighborhood Hits	285	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI68_MOUSE
θ value	3.0926 (rank : 143)	NC score	0.112602 (rank : 131)
Query Neighborhood Hits	192	Target Neighborhood Hits	356	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

CBLC_MOUSE
θ value	4.03905 (rank : 144)	NC score	0.189126 (rank : 41)
Query Neighborhood Hits	192	Target Neighborhood Hits	186	Shared Neighborhood Hits	90
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

DNPEP_HUMAN
θ value	4.03905 (rank : 145)	NC score	0.059037 (rank : 246)
Query Neighborhood Hits	192	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULA0, Q9BW44, Q9NUV5	Gene names	DNPEP
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

HUWE1_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.015337 (rank : 301)
Query Neighborhood Hits	192	Target Neighborhood Hits	443	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	4.03905 (rank : 147)	NC score	0.015511 (rank : 300)
Query Neighborhood Hits	192	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

RNF5_HUMAN
θ value	4.03905 (rank : 148)	NC score	0.188567 (rank : 43)
Query Neighborhood Hits	192	Target Neighborhood Hits	206	Shared Neighborhood Hits	95
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TERF2_MOUSE
θ value	4.03905 (rank : 149)	NC score	0.020980 (rank : 292)
Query Neighborhood Hits	192	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TRI59_MOUSE
θ value	4.03905 (rank : 150)	NC score	0.129001 (rank : 97)
Query Neighborhood Hits	192	Target Neighborhood Hits	292	Shared Neighborhood Hits	82
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI68_HUMAN
θ value	4.03905 (rank : 151)	NC score	0.105982 (rank : 143)
Query Neighborhood Hits	192	Target Neighborhood Hits	267	Shared Neighborhood Hits	89
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

LNX2_MOUSE
θ value	5.27518 (rank : 152)	NC score	0.087352 (rank : 191)
Query Neighborhood Hits	192	Target Neighborhood Hits	407	Shared Neighborhood Hits	91
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MATR3_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.016588 (rank : 299)
Query Neighborhood Hits	192	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NCOA2_MOUSE
θ value	5.27518 (rank : 154)	NC score	0.013492 (rank : 306)
Query Neighborhood Hits	192	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

PIAS3_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.019674 (rank : 295)
Query Neighborhood Hits	192	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PJA1_MOUSE
θ value	5.27518 (rank : 156)	NC score	0.093262 (rank : 172)
Query Neighborhood Hits	192	Target Neighborhood Hits	145	Shared Neighborhood Hits	46
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PKNX2_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.009145 (rank : 316)
Query Neighborhood Hits	192	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

RN125_MOUSE
θ value	5.27518 (rank : 158)	NC score	0.146876 (rank : 73)
Query Neighborhood Hits	192	Target Neighborhood Hits	220	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TJAP1_MOUSE
θ value	5.27518 (rank : 159)	NC score	0.022553 (rank : 288)
Query Neighborhood Hits	192	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TOPRS_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.134812 (rank : 87)
Query Neighborhood Hits	192	Target Neighborhood Hits	286	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	5.27518 (rank : 161)	NC score	0.137702 (rank : 79)
Query Neighborhood Hits	192	Target Neighborhood Hits	263	Shared Neighborhood Hits	78
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI10_HUMAN
θ value	5.27518 (rank : 162)	NC score	0.111670 (rank : 132)
Query Neighborhood Hits	192	Target Neighborhood Hits	315	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI39_HUMAN
θ value	5.27518 (rank : 163)	NC score	0.120363 (rank : 108)
Query Neighborhood Hits	192	Target Neighborhood Hits	693	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

ZN409_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.008069 (rank : 319)
Query Neighborhood Hits	192	Target Neighborhood Hits	842	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

ZN447_HUMAN
θ value	5.27518 (rank : 165)	NC score	0.000144 (rank : 323)
Query Neighborhood Hits	192	Target Neighborhood Hits	899	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

ZN598_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.030073 (rank : 281)
Query Neighborhood Hits	192	Target Neighborhood Hits	339	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ERCC1_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.017723 (rank : 298)
Query Neighborhood Hits	192	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

K1196_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.008357 (rank : 317)
Query Neighborhood Hits	192	Target Neighborhood Hits	618	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

NFAC2_MOUSE
θ value	6.88961 (rank : 169)	NC score	0.010650 (rank : 312)
Query Neighborhood Hits	192	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

PCGF6_MOUSE
θ value	6.88961 (rank : 170)	NC score	0.069712 (rank : 232)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RNF5_MOUSE
θ value	6.88961 (rank : 171)	NC score	0.182846 (rank : 47)
Query Neighborhood Hits	192	Target Neighborhood Hits	206	Shared Neighborhood Hits	96
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

SPRL1_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.015174 (rank : 302)
Query Neighborhood Hits	192	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TRI25_HUMAN
θ value	6.88961 (rank : 173)	NC score	0.146036 (rank : 74)
Query Neighborhood Hits	192	Target Neighborhood Hits	472	Shared Neighborhood Hits	95
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI34_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.100416 (rank : 151)
Query Neighborhood Hits	192	Target Neighborhood Hits	416	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI63_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.095200 (rank : 165)
Query Neighborhood Hits	192	Target Neighborhood Hits	298	Shared Neighborhood Hits	62
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM3_MOUSE
θ value	6.88961 (rank : 176)	NC score	0.121978 (rank : 103)
Query Neighborhood Hits	192	Target Neighborhood Hits	351	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

WDR22_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.007966 (rank : 320)
Query Neighborhood Hits	192	Target Neighborhood Hits	302	Shared Neighborhood Hits	5
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

AUXI_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.021651 (rank : 290)
Query Neighborhood Hits	192	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

BAG3_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.012458 (rank : 309)
Query Neighborhood Hits	192	Target Neighborhood Hits	314	Shared Neighborhood Hits	9
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CMTA2_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.013461 (rank : 307)
Query Neighborhood Hits	192	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CSK21_HUMAN
θ value	8.99809 (rank : 181)	NC score	-0.001563 (rank : 324)
Query Neighborhood Hits	192	Target Neighborhood Hits	772	Shared Neighborhood Hits	4
SwissProt Accessions	P68400, P19138, P20426, Q14013	Gene names	CSNK2A1, CK2A1
Domain Architecture	No domain graphic available
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

IF4G1_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.009791 (rank : 313)
Query Neighborhood Hits	192	Target Neighborhood Hits	347	Shared Neighborhood Hits	12
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MILK1_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.009684 (rank : 314)
Query Neighborhood Hits	192	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MYST3_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.011625 (rank : 311)
Query Neighborhood Hits	192	Target Neighborhood Hits	772	Shared Neighborhood Hits	24
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PCGF6_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.077101 (rank : 217)
Query Neighborhood Hits	192	Target Neighborhood Hits	178	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PP1RA_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.014341 (rank : 304)
Query Neighborhood Hits	192	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

RAG1_MOUSE
θ value	8.99809 (rank : 187)	NC score	0.091656 (rank : 180)
Query Neighborhood Hits	192	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RAI1_MOUSE
θ value	8.99809 (rank : 188)	NC score	0.020553 (rank : 293)
Query Neighborhood Hits	192	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SMRCD_HUMAN
θ value	8.99809 (rank : 189)	NC score	0.008323 (rank : 318)
Query Neighborhood Hits	192	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

TRI63_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.097859 (rank : 160)
Query Neighborhood Hits	192	Target Neighborhood Hits	240	Shared Neighborhood Hits	62
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

ZN598_MOUSE
θ value	8.99809 (rank : 191)	NC score	0.026721 (rank : 285)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZO3_MOUSE
θ value	8.99809 (rank : 192)	NC score	0.014528 (rank : 303)
Query Neighborhood Hits	192	Target Neighborhood Hits	224	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

BFAR_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.113514 (rank : 125)
Query Neighborhood Hits	192	Target Neighborhood Hits	222	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.116532 (rank : 116)
Query Neighborhood Hits	192	Target Neighborhood Hits	232	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BIRC5_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.055690 (rank : 256)
Query Neighborhood Hits	192	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

BIRC5_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.058550 (rank : 247)
Query Neighborhood Hits	192	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BRCA1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.099460 (rank : 153)
Query Neighborhood Hits	192	Target Neighborhood Hits	381	Shared Neighborhood Hits	87
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.102583 (rank : 147)
Query Neighborhood Hits	192	Target Neighborhood Hits	436	Shared Neighborhood Hits	95
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BSPRY_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.057657 (rank : 251)
Query Neighborhood Hits	192	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.063638 (rank : 240)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	33
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

DTX3L_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.053664 (rank : 266)
Query Neighborhood Hits	192	Target Neighborhood Hits	187	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.076481 (rank : 218)
Query Neighborhood Hits	192	Target Neighborhood Hits	198	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.070494 (rank : 230)
Query Neighborhood Hits	192	Target Neighborhood Hits	202	Shared Neighborhood Hits	76
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

DZIP3_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.065789 (rank : 234)
Query Neighborhood Hits	192	Target Neighborhood Hits	399	Shared Neighborhood Hits	41
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.072594 (rank : 225)
Query Neighborhood Hits	192	Target Neighborhood Hits	414	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

ERMAP_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.050497 (rank : 271)
Query Neighborhood Hits	192	Target Neighborhood Hits	155	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

LNX2_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.084903 (rank : 201)
Query Neighborhood Hits	192	Target Neighborhood Hits	389	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MEFV_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.061740 (rank : 241)
Query Neighborhood Hits	192	Target Neighborhood Hits	431	Shared Neighborhood Hits	43
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.054467 (rank : 262)
Query Neighborhood Hits	192	Target Neighborhood Hits	236	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.051173 (rank : 268)
Query Neighborhood Hits	192	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCGF2_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.057696 (rank : 250)
Query Neighborhood Hits	192	Target Neighborhood Hits	222	Shared Neighborhood Hits	55
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.056775 (rank : 253)
Query Neighborhood Hits	192	Target Neighborhood Hits	213	Shared Neighborhood Hits	53
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.058053 (rank : 248)
Query Neighborhood Hits	192	Target Neighborhood Hits	161	Shared Neighborhood Hits	57
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.057050 (rank : 252)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	55
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PJA1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.085086 (rank : 200)
Query Neighborhood Hits	192	Target Neighborhood Hits	159	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PZRN3_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.076102 (rank : 221)
Query Neighborhood Hits	192	Target Neighborhood Hits	461	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.076331 (rank : 219)
Query Neighborhood Hits	192	Target Neighborhood Hits	447	Shared Neighborhood Hits	99
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

R113B_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.090594 (rank : 182)
Query Neighborhood Hits	192	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAD18_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.082727 (rank : 206)
Query Neighborhood Hits	192	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.087311 (rank : 192)
Query Neighborhood Hits	192	Target Neighborhood Hits	230	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAG1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.083826 (rank : 204)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	65
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RFWD2_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.071964 (rank : 228)
Query Neighborhood Hits	192	Target Neighborhood Hits	518	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.074804 (rank : 222)
Query Neighborhood Hits	192	Target Neighborhood Hits	535	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.088807 (rank : 188)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	73
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.087089 (rank : 195)
Query Neighborhood Hits	192	Target Neighborhood Hits	220	Shared Neighborhood Hits	73
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.081788 (rank : 208)
Query Neighborhood Hits	192	Target Neighborhood Hits	201	Shared Neighborhood Hits	72
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.081781 (rank : 209)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN103_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.088877 (rank : 187)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.087050 (rank : 196)
Query Neighborhood Hits	192	Target Neighborhood Hits	143	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN122_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.097238 (rank : 161)
Query Neighborhood Hits	192	Target Neighborhood Hits	121	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.099714 (rank : 152)
Query Neighborhood Hits	192	Target Neighborhood Hits	121	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN123_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.051540 (rank : 267)
Query Neighborhood Hits	192	Target Neighborhood Hits	175	Shared Neighborhood Hits	70
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.054101 (rank : 264)
Query Neighborhood Hits	192	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN126_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.085287 (rank : 199)
Query Neighborhood Hits	192	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.093529 (rank : 170)
Query Neighborhood Hits	192	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN139_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.064233 (rank : 238)
Query Neighborhood Hits	192	Target Neighborhood Hits	130	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.064786 (rank : 237)
Query Neighborhood Hits	192	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN166_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.112704 (rank : 129)
Query Neighborhood Hits	192	Target Neighborhood Hits	240	Shared Neighborhood Hits	82
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.113265 (rank : 127)
Query Neighborhood Hits	192	Target Neighborhood Hits	248	Shared Neighborhood Hits	84
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN169_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.109552 (rank : 134)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.070613 (rank : 229)
Query Neighborhood Hits	192	Target Neighborhood Hits	126	Shared Neighborhood Hits	47
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.061739 (rank : 242)
Query Neighborhood Hits	192	Target Neighborhood Hits	119	Shared Neighborhood Hits	45
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF12_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.081862 (rank : 207)
Query Neighborhood Hits	192	Target Neighborhood Hits	173	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF12_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.084892 (rank : 202)
Query Neighborhood Hits	192	Target Neighborhood Hits	159	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF32_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.063823 (rank : 239)
Query Neighborhood Hits	192	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.055536 (rank : 258)
Query Neighborhood Hits	192	Target Neighborhood Hits	129	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF38_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.086135 (rank : 198)
Query Neighborhood Hits	192	Target Neighborhood Hits	155	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF38_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.084333 (rank : 203)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF39_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.076194 (rank : 220)
Query Neighborhood Hits	192	Target Neighborhood Hits	200	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF41_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.107498 (rank : 139)
Query Neighborhood Hits	192	Target Neighborhood Hits	226	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.107294 (rank : 140)
Query Neighborhood Hits	192	Target Neighborhood Hits	224	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.107106 (rank : 141)
Query Neighborhood Hits	192	Target Neighborhood Hits	212	Shared Neighborhood Hits	81
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.103574 (rank : 146)
Query Neighborhood Hits	192	Target Neighborhood Hits	212	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF6_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.080921 (rank : 211)
Query Neighborhood Hits	192	Target Neighborhood Hits	157	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RO52_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.114270 (rank : 121)
Query Neighborhood Hits	192	Target Neighborhood Hits	419	Shared Neighborhood Hits	109
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

RO52_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.112681 (rank : 130)
Query Neighborhood Hits	192	Target Neighborhood Hits	360	Shared Neighborhood Hits	104
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

SIAH2_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.050282 (rank : 272)
Query Neighborhood Hits	192	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.050695 (rank : 270)
Query Neighborhood Hits	192	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SPRY4_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.054597 (rank : 261)
Query Neighborhood Hits	192	Target Neighborhood Hits	79	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.056572 (rank : 255)
Query Neighborhood Hits	192	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI11_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.101281 (rank : 148)
Query Neighborhood Hits	192	Target Neighborhood Hits	316	Shared Neighborhood Hits	97
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.100635 (rank : 149)
Query Neighborhood Hits	192	Target Neighborhood Hits	329	Shared Neighborhood Hits	98
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI12_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.118689 (rank : 112)
Query Neighborhood Hits	192	Target Neighborhood Hits	387	Shared Neighborhood Hits	92
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI13_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.120057 (rank : 110)
Query Neighborhood Hits	192	Target Neighborhood Hits	274	Shared Neighborhood Hits	92
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.122440 (rank : 101)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI14_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.072324 (rank : 227)
Query Neighborhood Hits	192	Target Neighborhood Hits	143	Shared Neighborhood Hits	34
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.072354 (rank : 226)
Query Neighborhood Hits	192	Target Neighborhood Hits	137	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI15_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.099368 (rank : 154)
Query Neighborhood Hits	192	Target Neighborhood Hits	395	Shared Neighborhood Hits	90
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI16_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.073701 (rank : 223)
Query Neighborhood Hits	192	Target Neighborhood Hits	231	Shared Neighborhood Hits	28
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.080694 (rank : 212)
Query Neighborhood Hits	192	Target Neighborhood Hits	196	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI17_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.099089 (rank : 156)
Query Neighborhood Hits	192	Target Neighborhood Hits	318	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI17_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.095790 (rank : 163)
Query Neighborhood Hits	192	Target Neighborhood Hits	620	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI22_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.105029 (rank : 145)
Query Neighborhood Hits	192	Target Neighborhood Hits	396	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI27_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.095978 (rank : 162)
Query Neighborhood Hits	192	Target Neighborhood Hits	273	Shared Neighborhood Hits	94
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.098360 (rank : 159)
Query Neighborhood Hits	192	Target Neighborhood Hits	261	Shared Neighborhood Hits	94
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI29_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.069232 (rank : 233)
Query Neighborhood Hits	192	Target Neighborhood Hits	273	Shared Neighborhood Hits	30
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.070480 (rank : 231)
Query Neighborhood Hits	192	Target Neighborhood Hits	306	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI31_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.132011 (rank : 92)
Query Neighborhood Hits	192	Target Neighborhood Hits	299	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.092262 (rank : 175)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	72
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.091856 (rank : 178)
Query Neighborhood Hits	192	Target Neighborhood Hits	271	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI34_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.087108 (rank : 194)
Query Neighborhood Hits	192	Target Neighborhood Hits	332	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI35_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.121673 (rank : 104)
Query Neighborhood Hits	192	Target Neighborhood Hits	382	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.121173 (rank : 107)
Query Neighborhood Hits	192	Target Neighborhood Hits	465	Shared Neighborhood Hits	103
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI36_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.078849 (rank : 213)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.077818 (rank : 215)
Query Neighborhood Hits	192	Target Neighborhood Hits	266	Shared Neighborhood Hits	57
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI38_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.089815 (rank : 185)
Query Neighborhood Hits	192	Target Neighborhood Hits	373	Shared Neighborhood Hits	77
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI39_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.115380 (rank : 118)
Query Neighborhood Hits	192	Target Neighborhood Hits	691	Shared Neighborhood Hits	110
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI40_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.134604 (rank : 88)
Query Neighborhood Hits	192	Target Neighborhood Hits	279	Shared Neighborhood Hits	91
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI41_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.087807 (rank : 190)
Query Neighborhood Hits	192	Target Neighborhood Hits	349	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI42_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.065749 (rank : 235)
Query Neighborhood Hits	192	Target Neighborhood Hits	283	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.065744 (rank : 236)
Query Neighborhood Hits	192	Target Neighborhood Hits	316	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.054694 (rank : 260)
Query Neighborhood Hits	192	Target Neighborhood Hits	393	Shared Neighborhood Hits	35
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.056738 (rank : 254)
Query Neighborhood Hits	192	Target Neighborhood Hits	327	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI45_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.054717 (rank : 259)
Query Neighborhood Hits	192	Target Neighborhood Hits	155	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.054075 (rank : 265)
Query Neighborhood Hits	192	Target Neighborhood Hits	155	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI46_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.094703 (rank : 167)
Query Neighborhood Hits	192	Target Neighborhood Hits	291	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.094266 (rank : 169)
Query Neighborhood Hits	192	Target Neighborhood Hits	287	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI48_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.092035 (rank : 176)
Query Neighborhood Hits	192	Target Neighborhood Hits	192	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI49_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.078600 (rank : 214)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI52_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.114386 (rank : 120)
Query Neighborhood Hits	192	Target Neighborhood Hits	213	Shared Neighborhood Hits	81
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI54_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.090309 (rank : 183)
Query Neighborhood Hits	192	Target Neighborhood Hits	209	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.089266 (rank : 186)
Query Neighborhood Hits	192	Target Neighborhood Hits	197	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.090123 (rank : 184)
Query Neighborhood Hits	192	Target Neighborhood Hits	292	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI56_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.113682 (rank : 124)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	86
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI60_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.098740 (rank : 157)
Query Neighborhood Hits	192	Target Neighborhood Hits	240	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI62_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.093337 (rank : 171)
Query Neighborhood Hits	192	Target Neighborhood Hits	584	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.094980 (rank : 166)
Query Neighborhood Hits	192	Target Neighborhood Hits	478	Shared Neighborhood Hits	86
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM2_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.122433 (rank : 102)
Query Neighborhood Hits	192	Target Neighborhood Hits	330	Shared Neighborhood Hits	103
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.121417 (rank : 106)
Query Neighborhood Hits	192	Target Neighborhood Hits	331	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.118621 (rank : 113)
Query Neighborhood Hits	192	Target Neighborhood Hits	357	Shared Neighborhood Hits	100
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM4_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.109039 (rank : 137)
Query Neighborhood Hits	192	Target Neighborhood Hits	321	Shared Neighborhood Hits	96
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM5_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.113336 (rank : 126)
Query Neighborhood Hits	192	Target Neighborhood Hits	424	Shared Neighborhood Hits	97
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM6_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.098711 (rank : 158)
Query Neighborhood Hits	192	Target Neighborhood Hits	412	Shared Neighborhood Hits	85
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM6_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.099109 (rank : 155)
Query Neighborhood Hits	192	Target Neighborhood Hits	451	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM7_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.092028 (rank : 177)
Query Neighborhood Hits	192	Target Neighborhood Hits	336	Shared Neighborhood Hits	76
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM7_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.092764 (rank : 174)
Query Neighborhood Hits	192	Target Neighborhood Hits	358	Shared Neighborhood Hits	77
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM8_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.114208 (rank : 122)
Query Neighborhood Hits	192	Target Neighborhood Hits	650	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.115479 (rank : 117)
Query Neighborhood Hits	192	Target Neighborhood Hits	674	Shared Neighborhood Hits	86
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

UHRF2_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.059258 (rank : 245)
Query Neighborhood Hits	192	Target Neighborhood Hits	269	Shared Neighborhood Hits	76
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.059382 (rank : 244)
Query Neighborhood Hits	192	Target Neighborhood Hits	275	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZN313_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.136440 (rank : 83)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN364_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.090940 (rank : 181)
Query Neighborhood Hits	192	Target Neighborhood Hits	140	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.087240 (rank : 193)
Query Neighborhood Hits	192	Target Neighborhood Hits	140	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.077609 (rank : 216)
Query Neighborhood Hits	192	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.073408 (rank : 224)
Query Neighborhood Hits	192	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

MGRN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	192	Target Neighborhood Hits	192	Shared Neighborhood Hits	192
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
NC score	0.976155 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	192	Target Neighborhood Hits	149	Shared Neighborhood Hits	130
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RNF26_HUMAN
NC score	0.501518 (rank : 3)	θ value	1.53129e-07 (rank : 3)
Query Neighborhood Hits	192	Target Neighborhood Hits	95	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

CGRF1_MOUSE
NC score	0.383772 (rank : 4)	θ value	3.19293e-05 (rank : 7)
Query Neighborhood Hits	192	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

NEURL_MOUSE
NC score	0.378116 (rank : 5)	θ value	8.40245e-06 (rank : 5)
Query Neighborhood Hits	192	Target Neighborhood Hits	106	Shared Neighborhood Hits	68
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

CGRF1_HUMAN
NC score	0.377832 (rank : 6)	θ value	8.40245e-06 (rank : 4)
Query Neighborhood Hits	192	Target Neighborhood Hits	51	Shared Neighborhood Hits	40
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

NEUL1_HUMAN
NC score	0.371676 (rank : 7)	θ value	1.87187e-05 (rank : 6)
Query Neighborhood Hits	192	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

RNF34_MOUSE
NC score	0.348925 (rank : 8)	θ value	0.00102713 (rank : 15)
Query Neighborhood Hits	192	Target Neighborhood Hits	160	Shared Neighborhood Hits	76
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.346299 (rank : 9)	θ value	0.00134147 (rank : 16)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	73
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RFFL_MOUSE
NC score	0.342689 (rank : 10)	θ value	0.000270298 (rank : 8)
Query Neighborhood Hits	192	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
NC score	0.335368 (rank : 11)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	192	Target Neighborhood Hits	175	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RN141_HUMAN
NC score	0.303702 (rank : 12)	θ value	0.000786445 (rank : 12)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.303625 (rank : 13)	θ value	0.000786445 (rank : 13)
Query Neighborhood Hits	192	Target Neighborhood Hits	200	Shared Neighborhood Hits	88
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

BIRC7_HUMAN
NC score	0.295514 (rank : 14)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	192	Target Neighborhood Hits	185	Shared Neighborhood Hits	94
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

RKHD1_HUMAN
NC score	0.285337 (rank : 15)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

BIRC3_HUMAN
NC score	0.263975 (rank : 16)	θ value	0.00665767 (rank : 24)
Query Neighborhood Hits	192	Target Neighborhood Hits	133	Shared Neighborhood Hits	74
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC2_HUMAN
NC score	0.257502 (rank : 17)	θ value	0.00509761 (rank : 22)
Query Neighborhood Hits	192	Target Neighborhood Hits	142	Shared Neighborhood Hits	74
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC3_MOUSE
NC score	0.257140 (rank : 18)	θ value	0.00869519 (rank : 26)
Query Neighborhood Hits	192	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC2_MOUSE
NC score	0.254812 (rank : 19)	θ value	0.00869519 (rank : 25)
Query Neighborhood Hits	192	Target Neighborhood Hits	137	Shared Neighborhood Hits	68
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

PEX10_HUMAN
NC score	0.252886 (rank : 20)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	106
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN165_HUMAN
NC score	0.241294 (rank : 21)	θ value	0.00175202 (rank : 18)
Query Neighborhood Hits	192	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

BIRC8_HUMAN
NC score	0.236745 (rank : 22)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	192	Target Neighborhood Hits	121	Shared Neighborhood Hits	69
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

RN185_HUMAN
NC score	0.217699 (rank : 23)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	192	Target Neighborhood Hits	213	Shared Neighborhood Hits	100
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.214373 (rank : 24)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	192	Target Neighborhood Hits	211	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

AMFR_MOUSE
NC score	0.210557 (rank : 25)	θ value	0.0431538 (rank : 38)
Query Neighborhood Hits	192	Target Neighborhood Hits	208	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

CBL_HUMAN
NC score	0.208327 (rank : 26)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	192	Target Neighborhood Hits	353	Shared Neighborhood Hits	108
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CHFR_MOUSE
NC score	0.207971 (rank : 27)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_HUMAN
NC score	0.207590 (rank : 28)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	98
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CBL_MOUSE
NC score	0.206485 (rank : 29)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	192	Target Neighborhood Hits	426	Shared Neighborhood Hits	112
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

AMFR2_HUMAN
NC score	0.204241 (rank : 30)	θ value	0.0431538 (rank : 37)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

TRI65_MOUSE
NC score	0.202934 (rank : 31)	θ value	0.00509761 (rank : 23)
Query Neighborhood Hits	192	Target Neighborhood Hits	340	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RN133_HUMAN
NC score	0.201842 (rank : 32)	θ value	0.00298849 (rank : 19)
Query Neighborhood Hits	192	Target Neighborhood Hits	108	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

BIRC4_MOUSE
NC score	0.200044 (rank : 33)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	192	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

CBLB_HUMAN
NC score	0.199941 (rank : 34)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	192	Target Neighborhood Hits	261	Shared Neighborhood Hits	103
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
NC score	0.199830 (rank : 35)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	192	Target Neighborhood Hits	277	Shared Neighborhood Hits	104
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

RNF8_MOUSE
NC score	0.199730 (rank : 36)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	192	Target Neighborhood Hits	618	Shared Neighborhood Hits	121
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

BIRC4_HUMAN
NC score	0.197921 (rank : 37)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	192	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

RN168_HUMAN
NC score	0.195625 (rank : 38)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	192	Target Neighborhood Hits	370	Shared Neighborhood Hits	101
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

CBLC_HUMAN
NC score	0.194570 (rank : 39)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	192	Target Neighborhood Hits	173	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

TRI47_HUMAN
NC score	0.193130 (rank : 40)	θ value	0.00298849 (rank : 21)
Query Neighborhood Hits	192	Target Neighborhood Hits	286	Shared Neighborhood Hits	91
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

CBLC_MOUSE
NC score	0.189126 (rank : 41)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	192	Target Neighborhood Hits	186	Shared Neighborhood Hits	90
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RNF8_HUMAN
NC score	0.189080 (rank : 42)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	192	Target Neighborhood Hits	622	Shared Neighborhood Hits	118
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF5_HUMAN
NC score	0.188567 (rank : 43)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	192	Target Neighborhood Hits	206	Shared Neighborhood Hits	95
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI47_MOUSE
NC score	0.187543 (rank : 44)	θ value	0.00869519 (rank : 27)
Query Neighborhood Hits	192	Target Neighborhood Hits	295	Shared Neighborhood Hits	91
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI65_HUMAN
NC score	0.183739 (rank : 45)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	192	Target Neighborhood Hits	330	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RN146_HUMAN
NC score	0.183249 (rank : 46)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	192	Target Neighborhood Hits	162	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RNF5_MOUSE
NC score	0.182846 (rank : 47)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	192	Target Neighborhood Hits	206	Shared Neighborhood Hits	96
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RN168_MOUSE
NC score	0.182671 (rank : 48)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	192	Target Neighborhood Hits	440	Shared Neighborhood Hits	97
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI26_MOUSE
NC score	0.182364 (rank : 49)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	192	Target Neighborhood Hits	339	Shared Neighborhood Hits	113
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

RN146_MOUSE
NC score	0.181403 (rank : 50)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	192	Target Neighborhood Hits	161	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

GOLI_HUMAN
NC score	0.181275 (rank : 51)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	192	Target Neighborhood Hits	137	Shared Neighborhood Hits	44
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
NC score	0.178887 (rank : 52)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	192	Target Neighborhood Hits	134	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

TRI26_HUMAN
NC score	0.175682 (rank : 53)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	192	Target Neighborhood Hits	335	Shared Neighborhood Hits	112
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

MDM4_HUMAN
NC score	0.173758 (rank : 54)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	192	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MDM2_HUMAN
NC score	0.173300 (rank : 55)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	192	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MDM2_MOUSE
NC score	0.168760 (rank : 56)	θ value	0.0961366 (rank : 47)
Query Neighborhood Hits	192	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

RN125_HUMAN
NC score	0.167354 (rank : 57)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	192	Target Neighborhood Hits	230	Shared Neighborhood Hits	87
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI37_HUMAN
NC score	0.163966 (rank : 58)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	192	Target Neighborhood Hits	307	Shared Neighborhood Hits	79
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.163868 (rank : 59)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	192	Target Neighborhood Hits	316	Shared Neighborhood Hits	79
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

LRSM1_MOUSE
NC score	0.163074 (rank : 60)	θ value	0.000461057 (rank : 10)
Query Neighborhood Hits	192	Target Neighborhood Hits	874	Shared Neighborhood Hits	73
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MYLIP_HUMAN
NC score	0.160392 (rank : 61)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	192	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

ZN313_MOUSE
NC score	0.159865 (rank : 62)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	192	Target Neighborhood Hits	273	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RN167_MOUSE
NC score	0.158275 (rank : 63)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	192	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

TRI25_MOUSE
NC score	0.156910 (rank : 64)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	192	Target Neighborhood Hits	446	Shared Neighborhood Hits	100
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

ZN179_HUMAN
NC score	0.156782 (rank : 65)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	192	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

RNF13_HUMAN
NC score	0.155306 (rank : 66)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	192	Target Neighborhood Hits	147	Shared Neighborhood Hits	53
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

TRI73_HUMAN
NC score	0.155118 (rank : 67)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	192	Target Neighborhood Hits	258	Shared Neighborhood Hits	97
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

RNF13_MOUSE
NC score	0.154541 (rank : 68)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	192	Target Neighborhood Hits	164	Shared Neighborhood Hits	58
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RN167_HUMAN
NC score	0.154536 (rank : 69)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	192	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

TRI74_HUMAN
NC score	0.150586 (rank : 70)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	192	Target Neighborhood Hits	249	Shared Neighborhood Hits	94
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

LRSM1_HUMAN
NC score	0.147487 (rank : 71)	θ value	0.000461057 (rank : 9)
Query Neighborhood Hits	192	Target Neighborhood Hits	1078	Shared Neighborhood Hits	71
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

TRI50_MOUSE
NC score	0.147294 (rank : 72)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	192	Target Neighborhood Hits	326	Shared Neighborhood Hits	105
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RN125_MOUSE
NC score	0.146876 (rank : 73)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	192	Target Neighborhood Hits	220	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI25_HUMAN
NC score	0.146036 (rank : 74)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	192	Target Neighborhood Hits	472	Shared Neighborhood Hits	95
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

RNF11_HUMAN
NC score	0.144084 (rank : 75)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	192	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
NC score	0.143758 (rank : 76)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	192	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

MYLIP_MOUSE
NC score	0.138087 (rank : 77)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	192	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

TRI30_MOUSE
NC score	0.138070 (rank : 78)	θ value	0.0148317 (rank : 30)
Query Neighborhood Hits	192	Target Neighborhood Hits	434	Shared Neighborhood Hits	88
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TOPRS_MOUSE
NC score	0.137702 (rank : 79)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	192	Target Neighborhood Hits	263	Shared Neighborhood Hits	78
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI56_HUMAN
NC score	0.137645 (rank : 80)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	192	Target Neighborhood Hits	339	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

CM007_MOUSE
NC score	0.137465 (rank : 81)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	192	Target Neighborhood Hits	416	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TRI50_HUMAN
NC score	0.136459 (rank : 82)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	192	Target Neighborhood Hits	294	Shared Neighborhood Hits	102
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ZN313_HUMAN
NC score	0.136440 (rank : 83)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRIM1_HUMAN
NC score	0.135306 (rank : 84)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	192	Target Neighborhood Hits	345	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

PML_HUMAN
NC score	0.134949 (rank : 85)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	192	Target Neighborhood Hits	248	Shared Neighborhood Hits	62
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRI18_MOUSE
NC score	0.134866 (rank : 86)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	192	Target Neighborhood Hits	292	Shared Neighborhood Hits	88
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TOPRS_HUMAN
NC score	0.134812 (rank : 87)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	192	Target Neighborhood Hits	286	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI40_HUMAN
NC score	0.134604 (rank : 88)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	192	Target Neighborhood Hits	279	Shared Neighborhood Hits	91
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM1_MOUSE
NC score	0.134103 (rank : 89)	θ value	0.279714 (rank : 61)
Query Neighborhood Hits	192	Target Neighborhood Hits	361	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

RNF24_MOUSE
NC score	0.133963 (rank : 90)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	192	Target Neighborhood Hits	124	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.133051 (rank : 91)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	192	Target Neighborhood Hits	122	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

TRI31_HUMAN
NC score	0.132011 (rank : 92)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	192	Target Neighborhood Hits	299	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRIM9_MOUSE
NC score	0.131444 (rank : 93)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	192	Target Neighborhood Hits	274	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRIM9_HUMAN
NC score	0.131152 (rank : 94)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	192	Target Neighborhood Hits	294	Shared Neighborhood Hits	64
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRI59_HUMAN
NC score	0.130210 (rank : 95)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	192	Target Neighborhood Hits	307	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI18_HUMAN
NC score	0.129967 (rank : 96)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	192	Target Neighborhood Hits	307	Shared Neighborhood Hits	86
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI59_MOUSE
NC score	0.129001 (rank : 97)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	192	Target Neighborhood Hits	292	Shared Neighborhood Hits	82
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI43_HUMAN
NC score	0.128212 (rank : 98)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	192	Target Neighborhood Hits	341	Shared Neighborhood Hits	101
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

CM007_HUMAN
NC score	0.124926 (rank : 99)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	192	Target Neighborhood Hits	422	Shared Neighborhood Hits	72
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRI60_HUMAN
NC score	0.124097 (rank : 100)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	192	Target Neighborhood Hits	357	Shared Neighborhood Hits	105
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI13_MOUSE
NC score	0.122440 (rank : 101)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRIM2_HUMAN
NC score	0.122433 (rank : 102)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	192	Target Neighborhood Hits	330	Shared Neighborhood Hits	103
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM3_MOUSE
NC score	0.121978 (rank : 103)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	192	Target Neighborhood Hits	351	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI35_HUMAN
NC score	0.121673 (rank : 104)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	192	Target Neighborhood Hits	382	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

LNX1_MOUSE
NC score	0.121567 (rank : 105)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	192	Target Neighborhood Hits	377	Shared Neighborhood Hits	91
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRIM2_MOUSE
NC score	0.121417 (rank : 106)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	192	Target Neighborhood Hits	331	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI35_MOUSE
NC score	0.121173 (rank : 107)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	192	Target Neighborhood Hits	465	Shared Neighborhood Hits	103
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI39_HUMAN
NC score	0.120363 (rank : 108)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	192	Target Neighborhood Hits	693	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

MIB1_MOUSE
NC score	0.120346 (rank : 109)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	192	Target Neighborhood Hits	471	Shared Neighborhood Hits	77
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

TRI13_HUMAN
NC score	0.120057 (rank : 110)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	192	Target Neighborhood Hits	274	Shared Neighborhood Hits	92
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

MIB1_HUMAN
NC score	0.119312 (rank : 111)	θ value	0.0113563 (rank : 28)
Query Neighborhood Hits	192	Target Neighborhood Hits	470	Shared Neighborhood Hits	77
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

TRI12_MOUSE
NC score	0.118689 (rank : 112)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	192	Target Neighborhood Hits	387	Shared Neighborhood Hits	92
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM3_HUMAN
NC score	0.118621 (rank : 113)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	192	Target Neighborhood Hits	357	Shared Neighborhood Hits	100
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

ZC3H5_HUMAN
NC score	0.117987 (rank : 114)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	192	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

PML_MOUSE
NC score	0.117022 (rank : 115)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	192	Target Neighborhood Hits	246	Shared Neighborhood Hits	54
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

BFAR_MOUSE
NC score	0.116532 (rank : 116)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	192	Target Neighborhood Hits	232	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRIM8_MOUSE
NC score	0.115479 (rank : 117)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	192	Target Neighborhood Hits	674	Shared Neighborhood Hits	86
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI39_MOUSE
NC score	0.115380 (rank : 118)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	192	Target Neighborhood Hits	691	Shared Neighborhood Hits	110
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

ZC3H5_MOUSE
NC score	0.115372 (rank : 119)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	192	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

TRI52_HUMAN
NC score	0.114386 (rank : 120)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	192	Target Neighborhood Hits	213	Shared Neighborhood Hits	81
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

RO52_HUMAN
NC score	0.114270 (rank : 121)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	192	Target Neighborhood Hits	419	Shared Neighborhood Hits	109
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRIM8_HUMAN
NC score	0.114208 (rank : 122)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	192	Target Neighborhood Hits	650	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

LNX1_HUMAN
NC score	0.114099 (rank : 123)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	192	Target Neighborhood Hits	379	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRI56_MOUSE
NC score	0.113682 (rank : 124)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	86
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

BFAR_HUMAN
NC score	0.113514 (rank : 125)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	192	Target Neighborhood Hits	222	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRIM5_HUMAN
NC score	0.113336 (rank : 126)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	192	Target Neighborhood Hits	424	Shared Neighborhood Hits	97
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

RN166_MOUSE
NC score	0.113265 (rank : 127)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	192	Target Neighborhood Hits	248	Shared Neighborhood Hits	84
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

MDM4_MOUSE
NC score	0.113142 (rank : 128)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	192	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

RN166_HUMAN
NC score	0.112704 (rank : 129)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	192	Target Neighborhood Hits	240	Shared Neighborhood Hits	82
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RO52_MOUSE
NC score	0.112681 (rank : 130)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	192	Target Neighborhood Hits	360	Shared Neighborhood Hits	104
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI68_MOUSE
NC score	0.112602 (rank : 131)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	192	Target Neighborhood Hits	356	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI10_HUMAN
NC score	0.111670 (rank : 132)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	192	Target Neighborhood Hits	315	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI10_MOUSE
NC score	0.110236 (rank : 133)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	192	Target Neighborhood Hits	285	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

RN169_HUMAN
NC score	0.109552 (rank : 134)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

SMRA3_HUMAN
NC score	0.109211 (rank : 135)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	192	Target Neighborhood Hits	265	Shared Neighborhood Hits	96
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
NC score	0.109039 (rank : 136)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	192	Target Neighborhood Hits	267	Shared Neighborhood Hits	95
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRIM4_HUMAN
NC score	0.109039 (rank : 137)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	192	Target Neighborhood Hits	321	Shared Neighborhood Hits	96
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

R113A_HUMAN
NC score	0.107670 (rank : 138)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	192	Target Neighborhood Hits	177	Shared Neighborhood Hits	63
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RNF41_HUMAN
NC score	0.107498 (rank : 139)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	192	Target Neighborhood Hits	226	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.107294 (rank : 140)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	192	Target Neighborhood Hits	224	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
NC score	0.107106 (rank : 141)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	192	Target Neighborhood Hits	212	Shared Neighborhood Hits	81
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRAF6_HUMAN
NC score	0.106237 (rank : 142)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	192	Target Neighborhood Hits	267	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI68_HUMAN
NC score	0.105982 (rank : 143)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	192	Target Neighborhood Hits	267	Shared Neighborhood Hits	89
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRAF6_MOUSE
NC score	0.105930 (rank : 144)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	78
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI22_HUMAN
NC score	0.105029 (rank : 145)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	192	Target Neighborhood Hits	396	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

RNF4_MOUSE
NC score	0.103574 (rank : 146)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	192	Target Neighborhood Hits	212	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

BRCA1_MOUSE
NC score	0.102583 (rank : 147)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	192	Target Neighborhood Hits	436	Shared Neighborhood Hits	95
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TRI11_HUMAN
NC score	0.101281 (rank : 148)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	192	Target Neighborhood Hits	316	Shared Neighborhood Hits	97
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
NC score	0.100635 (rank : 149)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	192	Target Neighborhood Hits	329	Shared Neighborhood Hits	98
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

DNPEP_MOUSE
NC score	0.100591 (rank : 150)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	192	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2W0	Gene names	Dnpep
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

TRI34_HUMAN
NC score	0.100416 (rank : 151)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	192	Target Neighborhood Hits	416	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

RN122_MOUSE
NC score	0.099714 (rank : 152)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	192	Target Neighborhood Hits	121	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

BRCA1_HUMAN
NC score	0.099460 (rank : 153)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	192	Target Neighborhood Hits	381	Shared Neighborhood Hits	87
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRI15_HUMAN
NC score	0.099368 (rank : 154)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	192	Target Neighborhood Hits	395	Shared Neighborhood Hits	90
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRIM6_MOUSE
NC score	0.099109 (rank : 155)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	192	Target Neighborhood Hits	451	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI17_HUMAN
NC score	0.099089 (rank : 156)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	192	Target Neighborhood Hits	318	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI60_MOUSE
NC score	0.098740 (rank : 157)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	192	Target Neighborhood Hits	240	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRIM6_HUMAN
NC score	0.098711 (rank : 158)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	192	Target Neighborhood Hits	412	Shared Neighborhood Hits	85
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI27_MOUSE
NC score	0.098360 (rank : 159)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	192	Target Neighborhood Hits	261	Shared Neighborhood Hits	94
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI63_MOUSE
NC score	0.097859 (rank : 160)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	192	Target Neighborhood Hits	240	Shared Neighborhood Hits	62
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

RN122_HUMAN
NC score	0.097238 (rank : 161)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	192	Target Neighborhood Hits	121	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

TRI27_HUMAN
NC score	0.095978 (rank : 162)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	192	Target Neighborhood Hits	273	Shared Neighborhood Hits	94
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI17_MOUSE
NC score	0.095790 (rank : 163)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	192	Target Neighborhood Hits	620	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

RBBP6_MOUSE
NC score	0.095563 (rank : 164)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	192	Target Neighborhood Hits	1014	Shared Neighborhood Hits	83
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRI63_HUMAN
NC score	0.095200 (rank : 165)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	192	Target Neighborhood Hits	298	Shared Neighborhood Hits	62
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI62_MOUSE
NC score	0.094980 (rank : 166)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	192	Target Neighborhood Hits	478	Shared Neighborhood Hits	86
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI46_HUMAN
NC score	0.094703 (rank : 167)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	192	Target Neighborhood Hits	291	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

MIB2_HUMAN
NC score	0.094277 (rank : 168)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	192	Target Neighborhood Hits	438	Shared Neighborhood Hits	61
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

TRI46_MOUSE
NC score	0.094266 (rank : 169)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	192	Target Neighborhood Hits	287	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RN126_MOUSE
NC score	0.093529 (rank : 170)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	192	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

TRI62_HUMAN
NC score	0.093337 (rank : 171)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	192	Target Neighborhood Hits	584	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

PJA1_MOUSE
NC score	0.093262 (rank : 172)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	192	Target Neighborhood Hits	145	Shared Neighborhood Hits	46
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

MIB2_MOUSE
NC score	0.092932 (rank : 173)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	192	Target Neighborhood Hits	409	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

TRIM7_MOUSE
NC score	0.092764 (rank : 174)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	192	Target Neighborhood Hits	358	Shared Neighborhood Hits	77
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI32_HUMAN
NC score	0.092262 (rank : 175)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	72
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI48_HUMAN
NC score	0.092035 (rank : 176)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	192	Target Neighborhood Hits	192	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRIM7_HUMAN
NC score	0.092028 (rank : 177)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	192	Target Neighborhood Hits	336	Shared Neighborhood Hits	76
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI32_MOUSE
NC score	0.091856 (rank : 178)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	192	Target Neighborhood Hits	271	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

PZRN4_HUMAN
NC score	0.091783 (rank : 179)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	192	Target Neighborhood Hits	438	Shared Neighborhood Hits	97
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RAG1_MOUSE
NC score	0.091656 (rank : 180)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	192	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

ZN364_HUMAN
NC score	0.090940 (rank : 181)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	192	Target Neighborhood Hits	140	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

R113B_HUMAN
NC score	0.090594 (rank : 182)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	192	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TRI54_HUMAN
NC score	0.090309 (rank : 183)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	192	Target Neighborhood Hits	209	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
NC score	0.090123 (rank : 184)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	192	Target Neighborhood Hits	292	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI38_HUMAN
NC score	0.089815 (rank : 185)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	192	Target Neighborhood Hits	373	Shared Neighborhood Hits	77
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI54_MOUSE
NC score	0.089266 (rank : 186)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	192	Target Neighborhood Hits	197	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

RN103_HUMAN
NC score	0.088877 (rank : 187)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RING1_HUMAN
NC score	0.088807 (rank : 188)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	73
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

CB017_HUMAN
NC score	0.088160 (rank : 189)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	192	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

TRI41_HUMAN
NC score	0.087807 (rank : 190)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	192	Target Neighborhood Hits	349	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

LNX2_MOUSE
NC score	0.087352 (rank : 191)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	192	Target Neighborhood Hits	407	Shared Neighborhood Hits	91
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RAD18_MOUSE
NC score	0.087311 (rank : 192)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	192	Target Neighborhood Hits	230	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

ZN364_MOUSE
NC score	0.087240 (rank : 193)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	192	Target Neighborhood Hits	140	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

TRI34_MOUSE
NC score	0.087108 (rank : 194)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	192	Target Neighborhood Hits	332	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

RING1_MOUSE
NC score	0.087089 (rank : 195)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	192	Target Neighborhood Hits	220	Shared Neighborhood Hits	73
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RN103_MOUSE
NC score	0.087050 (rank : 196)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	192	Target Neighborhood Hits	143	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RBBP6_HUMAN
NC score	0.086504 (rank : 197)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	192	Target Neighborhood Hits	1135	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RNF38_HUMAN
NC score	0.086135 (rank : 198)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	192	Target Neighborhood Hits	155	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN126_HUMAN
NC score	0.085287 (rank : 199)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	192	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

PJA1_HUMAN
NC score	0.085086 (rank : 200)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	192	Target Neighborhood Hits	159	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

LNX2_HUMAN
NC score	0.084903 (rank : 201)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	192	Target Neighborhood Hits	389	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RNF12_MOUSE
NC score	0.084892 (rank : 202)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	192	Target Neighborhood Hits	159	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF38_MOUSE
NC score	0.084333 (rank : 203)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RAG1_HUMAN
NC score	0.083826 (rank : 204)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	65
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

CB017_MOUSE
NC score	0.083484 (rank : 205)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	192	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NS82, Q3TA48, Q8BSD3, Q8CHY1, Q8R0Q3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17 homolog.

RAD18_HUMAN
NC score	0.082727 (rank : 206)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	192	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RNF12_HUMAN
NC score	0.081862 (rank : 207)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	192	Target Neighborhood Hits	173	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RING2_HUMAN
NC score	0.081788 (rank : 208)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	192	Target Neighborhood Hits	201	Shared Neighborhood Hits	72
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.081781 (rank : 209)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

TENS1_HUMAN
NC score	0.081173 (rank : 210)	θ value	0.000602161 (rank : 11)
Query Neighborhood Hits	192	Target Neighborhood Hits	400	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

RNF6_HUMAN
NC score	0.080921 (rank : 211)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	192	Target Neighborhood Hits	157	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

TRI16_MOUSE
NC score	0.080694 (rank : 212)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	192	Target Neighborhood Hits	196	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI36_HUMAN
NC score	0.078849 (rank : 213)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI49_HUMAN
NC score	0.078600 (rank : 214)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI36_MOUSE
NC score	0.077818 (rank : 215)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	192	Target Neighborhood Hits	266	Shared Neighborhood Hits	57
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

ZSWM2_HUMAN
NC score	0.077609 (rank : 216)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	192	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

PCGF6_HUMAN
NC score	0.077101 (rank : 217)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	192	Target Neighborhood Hits	178	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

DTX3_HUMAN
NC score	0.076481 (rank : 218)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	192	Target Neighborhood Hits	198	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

PZRN3_MOUSE
NC score	0.076331 (rank : 219)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	192	Target Neighborhood Hits	447	Shared Neighborhood Hits	99
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RNF39_HUMAN
NC score	0.076194 (rank : 220)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	192	Target Neighborhood Hits	200	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

PZRN3_HUMAN
NC score	0.076102 (rank : 221)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	192	Target Neighborhood Hits	461	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RFWD2_MOUSE
NC score	0.074804 (rank : 222)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	192	Target Neighborhood Hits	535	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRI16_HUMAN
NC score	0.073701 (rank : 223)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	192	Target Neighborhood Hits	231	Shared Neighborhood Hits	28
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

ZSWM2_MOUSE
NC score	0.073408 (rank : 224)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	192	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

DZIP3_MOUSE
NC score	0.072594 (rank : 225)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	192	Target Neighborhood Hits	414	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

TRI14_MOUSE
NC score	0.072354 (rank : 226)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	192	Target Neighborhood Hits	137	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI14_HUMAN
NC score	0.072324 (rank : 227)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	192	Target Neighborhood Hits	143	Shared Neighborhood Hits	34
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

RFWD2_HUMAN
NC score	0.071964 (rank : 228)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	192	Target Neighborhood Hits	518	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RN183_HUMAN
NC score	0.070613 (rank : 229)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	192	Target Neighborhood Hits	126	Shared Neighborhood Hits	47
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

DTX3_MOUSE
NC score	0.070494 (rank : 230)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	192	Target Neighborhood Hits	202	Shared Neighborhood Hits	76
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TRI29_MOUSE
NC score	0.070480 (rank : 231)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	192	Target Neighborhood Hits	306	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

PCGF6_MOUSE
NC score	0.069712 (rank : 232)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI29_HUMAN
NC score	0.069232 (rank : 233)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	192	Target Neighborhood Hits	273	Shared Neighborhood Hits	30
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

DZIP3_HUMAN
NC score	0.065789 (rank : 234)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	192	Target Neighborhood Hits	399	Shared Neighborhood Hits	41
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

TRI42_HUMAN
NC score	0.065749 (rank : 235)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	192	Target Neighborhood Hits	283	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
NC score	0.065744 (rank : 236)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	192	Target Neighborhood Hits	316	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

RN139_MOUSE
NC score	0.064786 (rank : 237)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	192	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN139_HUMAN
NC score	0.064233 (rank : 238)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	192	Target Neighborhood Hits	130	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RNF32_HUMAN
NC score	0.063823 (rank : 239)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	192	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

BSPRY_MOUSE
NC score	0.063638 (rank : 240)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	33
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

MEFV_HUMAN
NC score	0.061740 (rank : 241)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	192	Target Neighborhood Hits	431	Shared Neighborhood Hits	43
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

RN183_MOUSE
NC score	0.061739 (rank : 242)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	192	Target Neighborhood Hits	119	Shared Neighborhood Hits	45
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRAF7_HUMAN
NC score	0.059442 (rank : 243)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	192	Target Neighborhood Hits	482	Shared Neighborhood Hits	81
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

UHRF2_MOUSE
NC score	0.059382 (rank : 244)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	192	Target Neighborhood Hits	275	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

UHRF2_HUMAN
NC score	0.059258 (rank : 245)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	192	Target Neighborhood Hits	269	Shared Neighborhood Hits	76
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

DNPEP_HUMAN
NC score	0.059037 (rank : 246)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	192	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULA0, Q9BW44, Q9NUV5	Gene names	DNPEP
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

BIRC5_MOUSE
NC score	0.058550 (rank : 247)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	192	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

PCGF4_HUMAN
NC score	0.058053 (rank : 248)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	192	Target Neighborhood Hits	161	Shared Neighborhood Hits	57
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

TRAF7_MOUSE
NC score	0.058035 (rank : 249)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	192	Target Neighborhood Hits	470	Shared Neighborhood Hits	79
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

PCGF2_HUMAN
NC score	0.057696 (rank : 250)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	192	Target Neighborhood Hits	222	Shared Neighborhood Hits	55
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

BSPRY_HUMAN
NC score	0.057657 (rank : 251)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	192	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

PCGF4_MOUSE
NC score	0.057050 (rank : 252)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	55
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF2_MOUSE
NC score	0.056775 (rank : 253)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	192	Target Neighborhood Hits	213	Shared Neighborhood Hits	53
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TRI44_MOUSE
NC score	0.056738 (rank : 254)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	192	Target Neighborhood Hits	327	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

SPRY4_MOUSE
NC score	0.056572 (rank : 255)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	192	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BIRC5_HUMAN
NC score	0.055690 (rank : 256)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	192	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

SMRC2_HUMAN
NC score	0.055670 (rank : 257)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	192	Target Neighborhood Hits	499	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

RNF32_MOUSE
NC score	0.055536 (rank : 258)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	192	Target Neighborhood Hits	129	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

TRI45_HUMAN
NC score	0.054717 (rank : 259)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	192	Target Neighborhood Hits	155	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI44_HUMAN
NC score	0.054694 (rank : 260)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	192	Target Neighborhood Hits	393	Shared Neighborhood Hits	35
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

SPRY4_HUMAN
NC score	0.054597 (rank : 261)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	192	Target Neighborhood Hits	79	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

MEFV_MOUSE
NC score	0.054467 (rank : 262)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	192	Target Neighborhood Hits	236	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

SMRC2_MOUSE
NC score	0.054156 (rank : 263)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	192	Target Neighborhood Hits	487	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

RN123_MOUSE
NC score	0.054101 (rank : 264)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	192	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRI45_MOUSE
NC score	0.054075 (rank : 265)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	192	Target Neighborhood Hits	155	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

DTX3L_HUMAN
NC score	0.053664 (rank : 266)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	192	Target Neighborhood Hits	187	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RN123_HUMAN
NC score	0.051540 (rank : 267)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	192	Target Neighborhood Hits	175	Shared Neighborhood Hits	70
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

NHLC1_MOUSE
NC score	0.051173 (rank : 268)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	192	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

DIDO1_HUMAN
NC score	0.050734 (rank : 269)	θ value	0.0330416 (rank : 34)
Query Neighborhood Hits	192	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SIAH2_MOUSE
NC score	0.050695 (rank : 270)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	192	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

ERMAP_HUMAN
NC score	0.050497 (rank : 271)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	192	Target Neighborhood Hits	155	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

SIAH2_HUMAN
NC score	0.050282 (rank : 272)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	192	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

MAGAA_HUMAN
NC score	0.046763 (rank : 273)	θ value	0.00175202 (rank : 17)
Query Neighborhood Hits	192	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	P43363	Gene names	MAGEA10, MAGE10
Domain Architecture
Description	Melanoma-associated antigen 10 (MAGE-10 antigen).

UBE4B_HUMAN
NC score	0.046581 (rank : 274)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	192	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

SH3K1_HUMAN
NC score	0.044206 (rank : 275)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	192	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

CQ050_MOUSE
NC score	0.041960 (rank : 276)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	192	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C1R3, Q9DAI8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf50 homolog.

SH3K1_MOUSE
NC score	0.040183 (rank : 277)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	192	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

CABIN_HUMAN
NC score	0.036465 (rank : 278)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	192	Target Neighborhood Hits	490	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

MLL2_HUMAN
NC score	0.033740 (rank : 279)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	192	Target Neighborhood Hits	1788	Shared Neighborhood Hits	45
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SRRM2_HUMAN
NC score	0.031481 (rank : 280)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	192	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ZN598_HUMAN
NC score	0.030073 (rank : 281)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	192	Target Neighborhood Hits	339	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

NACAM_MOUSE
NC score	0.029637 (rank : 282)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	192	Target Neighborhood Hits	1866	Shared Neighborhood Hits	42
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DREB_HUMAN
NC score	0.028915 (rank : 283)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	192	Target Neighborhood Hits	450	Shared Neighborhood Hits	12
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

RPGF6_HUMAN
NC score	0.026769 (rank : 284)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	192	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

ZN598_MOUSE
NC score	0.026721 (rank : 285)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	192	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

PCLO_MOUSE
NC score	0.024244 (rank : 286)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	192	Target Neighborhood Hits	2275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MINT_MOUSE
NC score	0.022747 (rank : 287)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	192	Target Neighborhood Hits	1514	Shared Neighborhood Hits	29
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TJAP1_MOUSE
NC score	0.022553 (rank : 288)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	192	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

PIAS4_HUMAN
NC score	0.022356 (rank : 289)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	192	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

AUXI_HUMAN
NC score	0.021651 (rank : 290)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	192	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

TTBK1_HUMAN
NC score	0.021366 (rank : 291)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	192	Target Neighborhood Hits	1058	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TERF2_MOUSE
NC score	0.020980 (rank : 292)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	192	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

RAI1_MOUSE
NC score	0.020553 (rank : 293)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	192	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

MYCL1_MOUSE
NC score	0.020427 (rank : 294)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	192	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

PIAS3_MOUSE
NC score	0.019674 (rank : 295)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	192	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

NF2L3_MOUSE
NC score	0.019535 (rank : 296)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	192	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

RIMS2_MOUSE
NC score	0.018999 (rank : 297)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	192	Target Neighborhood Hits	376	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

ERCC1_HUMAN
NC score	0.017723 (rank : 298)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	192	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

MATR3_HUMAN
NC score	0.016588 (rank : 299)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	192	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

HUWE1_MOUSE
NC score	0.015511 (rank : 300)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	192	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.015337 (rank : 301)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	192	Target Neighborhood Hits	443	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

SPRL1_MOUSE
NC score	0.015174 (rank : 302)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	192	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

ZO3_MOUSE
NC score	0.014528 (rank : 303)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	192	Target Neighborhood Hits	224	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PP1RA_MOUSE
NC score	0.014341 (rank : 304)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	192	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

RHG06_MOUSE
NC score	0.014316 (rank : 305)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	192	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

NCOA2_MOUSE
NC score	0.013492 (rank : 306)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	192	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

CMTA2_MOUSE
NC score	0.013461 (rank : 307)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	192	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

AP2A1_MOUSE
NC score	0.012795 (rank : 308)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	192	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

BAG3_HUMAN
NC score	0.012458 (rank : 309)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	192	Target Neighborhood Hits	314	Shared Neighborhood Hits	9
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

NFH_HUMAN
NC score	0.011646 (rank : 310)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	192	Target Neighborhood Hits	1242	Shared Neighborhood Hits	27
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MYST3_HUMAN
NC score	0.011625 (rank : 311)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	192	Target Neighborhood Hits	772	Shared Neighborhood Hits	24
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFAC2_MOUSE
NC score	0.010650 (rank : 312)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	192	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

IF4G1_HUMAN
NC score	0.009791 (rank : 313)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	192	Target Neighborhood Hits	347	Shared Neighborhood Hits	12
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MILK1_HUMAN
NC score	0.009684 (rank : 314)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	192	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TLE2_MOUSE
NC score	0.009218 (rank : 315)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	192	Target Neighborhood Hits	294	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

PKNX2_HUMAN
NC score	0.009145 (rank : 316)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	192	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

K1196_HUMAN
NC score	0.008357 (rank : 317)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	192	Target Neighborhood Hits	618	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

SMRCD_HUMAN
NC score	0.008323 (rank : 318)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	192	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

ZN409_HUMAN
NC score	0.008069 (rank : 319)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	192	Target Neighborhood Hits	842	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

WDR22_MOUSE
NC score	0.007966 (rank : 320)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	192	Target Neighborhood Hits	302	Shared Neighborhood Hits	5
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

PRDM2_HUMAN
NC score	0.007662 (rank : 321)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	192	Target Neighborhood Hits	1135	Shared Neighborhood Hits	20
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SPEG_HUMAN
NC score	0.002959 (rank : 322)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	192	Target Neighborhood Hits	1762	Shared Neighborhood Hits	19
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZN447_HUMAN
NC score	0.000144 (rank : 323)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	192	Target Neighborhood Hits	899	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

CSK21_HUMAN
NC score	-0.001563 (rank : 324)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	192	Target Neighborhood Hits	772	Shared Neighborhood Hits	4
SwissProt Accessions	P68400, P19138, P20426, Q14013	Gene names	CSNK2A1, CK2A1
Domain Architecture	No domain graphic available
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

GFI1_HUMAN
NC score	-0.001692 (rank : 325)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	192	Target Neighborhood Hits	726	Shared Neighborhood Hits	9
SwissProt Accessions	Q99684, Q8N564	Gene names	GFI1, ZNF163
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).