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Network neighborhood for query Sequence : ERCC1_HUMAN

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ERCC1_HUMAN
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERCC1_HUMAN
θ value	1.66873e-171 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

ERCC1_MOUSE
θ value	9.22056e-146 (rank : 2)	NC score	0.983555 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	P07903	Gene names	Ercc1, Ercc-1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

WBS14_HUMAN
θ value	0.0431538 (rank : 3)	NC score	0.071738 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	273	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

SPHK2_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.061408 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

B3A3_HUMAN
θ value	0.279714 (rank : 5)	NC score	0.041065 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

SOX30_MOUSE
θ value	0.47712 (rank : 6)	NC score	0.035652 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	374	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ARI5B_HUMAN
θ value	0.62314 (rank : 7)	NC score	0.042831 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	328	Shared Neighborhood Hits	3
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

CTNL1_HUMAN
θ value	0.62314 (rank : 8)	NC score	0.040906 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBT7, O76084, Q53FQ2, Q5JTQ7, Q5JTQ8, Q9Y401	Gene names	CTNNAL1
Domain Architecture	No domain graphic available
Description	Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) (ACRP).

B3A3_MOUSE
θ value	1.06291 (rank : 9)	NC score	0.037766 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

SYN1_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.041329 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	419	Shared Neighborhood Hits	11
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

CO8A1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.021993 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	288	Shared Neighborhood Hits	6
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

CO8A1_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.021747 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	251	Shared Neighborhood Hits	5
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

CBP_HUMAN
θ value	1.81305 (rank : 13)	NC score	0.026968 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	941	Shared Neighborhood Hits	15
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SYN1_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.040202 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	363	Shared Neighborhood Hits	10
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TM108_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.034428 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	336	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

IF4G1_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.021965 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	534	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

SMC2_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.015079 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	1405	Shared Neighborhood Hits	5
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC2_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.018130 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	1131	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

ALEX_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.031571 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	361	Shared Neighborhood Hits	11
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SGIP1_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.036185 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SOX13_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.021687 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	464	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ELN_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.024657 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

G3BP_MOUSE
θ value	5.27518 (rank : 23)	NC score	0.016471 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

PO121_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.019614 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	344	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

BSN_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.023164 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	1537	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.023355 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	2057	Shared Neighborhood Hits	20
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD1A_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.020403 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

M3K2_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.001074 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	846	Shared Neighborhood Hits	2
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

MGRN1_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.017723 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

SHAN2_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.015731 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	346	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

TGM2_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.015160 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P21981, O88901, Q9R1F7	Gene names	Tgm2
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (TGase C) (TGC) (TG(C)) (Transglutaminase-2).

CSKI1_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.005784 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	997	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

K0889_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.024028 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O94964	Gene names	KIAA0889
Domain Architecture	No domain graphic available
Description	Protein KIAA0889.

SGIP1_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.029607 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

Hits sorted by NC score

ERCC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.66873e-171 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

ERCC1_MOUSE
NC score	0.983555 (rank : 2)	θ value	9.22056e-146 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	P07903	Gene names	Ercc1, Ercc-1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

WBS14_HUMAN
NC score	0.071738 (rank : 3)	θ value	0.0431538 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	273	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

SPHK2_HUMAN
NC score	0.061408 (rank : 4)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

ARI5B_HUMAN
NC score	0.042831 (rank : 5)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	328	Shared Neighborhood Hits	3
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

SYN1_HUMAN
NC score	0.041329 (rank : 6)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	419	Shared Neighborhood Hits	11
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

B3A3_HUMAN
NC score	0.041065 (rank : 7)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

CTNL1_HUMAN
NC score	0.040906 (rank : 8)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBT7, O76084, Q53FQ2, Q5JTQ7, Q5JTQ8, Q9Y401	Gene names	CTNNAL1
Domain Architecture	No domain graphic available
Description	Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) (ACRP).

SYN1_MOUSE
NC score	0.040202 (rank : 9)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	363	Shared Neighborhood Hits	10
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

B3A3_MOUSE
NC score	0.037766 (rank : 10)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

SGIP1_HUMAN
NC score	0.036185 (rank : 11)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SOX30_MOUSE
NC score	0.035652 (rank : 12)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	374	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

TM108_MOUSE
NC score	0.034428 (rank : 13)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	336	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ALEX_HUMAN
NC score	0.031571 (rank : 14)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	361	Shared Neighborhood Hits	11
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SGIP1_MOUSE
NC score	0.029607 (rank : 15)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CBP_HUMAN
NC score	0.026968 (rank : 16)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	941	Shared Neighborhood Hits	15
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ELN_HUMAN
NC score	0.024657 (rank : 17)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

K0889_HUMAN
NC score	0.024028 (rank : 18)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O94964	Gene names	KIAA0889
Domain Architecture	No domain graphic available
Description	Protein KIAA0889.

BSN_MOUSE
NC score	0.023355 (rank : 19)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	2057	Shared Neighborhood Hits	20
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BSN_HUMAN
NC score	0.023164 (rank : 20)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	1537	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CO8A1_HUMAN
NC score	0.021993 (rank : 21)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	288	Shared Neighborhood Hits	6
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

IF4G1_MOUSE
NC score	0.021965 (rank : 22)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	534	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

CO8A1_MOUSE
NC score	0.021747 (rank : 23)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	251	Shared Neighborhood Hits	5
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

SOX13_HUMAN
NC score	0.021687 (rank : 24)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	464	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

CCD1A_HUMAN
NC score	0.020403 (rank : 25)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

PO121_HUMAN
NC score	0.019614 (rank : 26)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	344	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SMC2_MOUSE
NC score	0.018130 (rank : 27)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	1131	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

MGRN1_HUMAN
NC score	0.017723 (rank : 28)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

G3BP_MOUSE
NC score	0.016471 (rank : 29)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

SHAN2_HUMAN
NC score	0.015731 (rank : 30)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	346	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

TGM2_MOUSE
NC score	0.015160 (rank : 31)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P21981, O88901, Q9R1F7	Gene names	Tgm2
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (TGase C) (TGC) (TG(C)) (Transglutaminase-2).

SMC2_HUMAN
NC score	0.015079 (rank : 32)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	1405	Shared Neighborhood Hits	5
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CSKI1_HUMAN
NC score	0.005784 (rank : 33)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	997	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

M3K2_MOUSE
NC score	0.001074 (rank : 34)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	846	Shared Neighborhood Hits	2
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).