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Network neighborhood for query Sequence : PIAS3_MOUSE

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PIAS3_MOUSE
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PIAS1_HUMAN
θ value	0 (rank : 1)	NC score	0.986316 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

PIAS3_HUMAN
θ value	0 (rank : 2)	NC score	0.997174 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS1_MOUSE
θ value	1.90044e-183 (rank : 4)	NC score	0.986282 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

PIAS2_HUMAN
θ value	4.70271e-166 (rank : 5)	NC score	0.985690 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	O75928, O75927, Q96BT5, Q96KE3	Gene names	PIAS2, PIASX
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (Miz1) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) (PIAS-NY protein).

PIAS2_MOUSE
θ value	4.70271e-166 (rank : 6)	NC score	0.985734 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C5D8, O54987, Q8C384, Q8CDQ8, Q8K208, Q99JX5, Q9D5W7, Q9QZ63	Gene names	Pias2, Miz1, Piasx
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3).

PIAS4_HUMAN
θ value	3.09092e-117 (rank : 7)	NC score	0.973768 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

PIAS4_MOUSE
θ value	2.2151e-115 (rank : 8)	NC score	0.973583 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JM05, Q8R165	Gene names	Pias4, Piasg
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

ZIM10_HUMAN
θ value	7.32683e-18 (rank : 9)	NC score	0.487379 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	577	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_MOUSE
θ value	1.24977e-17 (rank : 10)	NC score	0.526641 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	430	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIMP7_HUMAN
θ value	2.60593e-15 (rank : 11)	NC score	0.566733 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIMP7_MOUSE
θ value	3.40345e-15 (rank : 12)	NC score	0.509692 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	566	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

TENS1_HUMAN
θ value	0.00665767 (rank : 13)	NC score	0.053006 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	400	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

FBX7_HUMAN
θ value	0.0563607 (rank : 14)	NC score	0.085913 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3I1, Q5TGC4, Q96HM6, Q9UF21, Q9UKT2	Gene names	FBXO7, FBX7
Domain Architecture	No domain graphic available
Description	F-box only protein 7.

BC11B_MOUSE
θ value	0.0736092 (rank : 15)	NC score	0.006095 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	767	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

CCD1A_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.025698 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

HEY1_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.037961 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

BRCA1_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.019082 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	436	Shared Neighborhood Hits	3
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

ZN364_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.054155 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

CSKI1_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.007254 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	1031	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ZN364_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.050752 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

CUED1_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.041871 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3V6	Gene names	Cuedc1
Domain Architecture
Description	CUE domain-containing protein 1.

EPN2_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.035883 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

MBD6_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.034444 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	349	Shared Neighborhood Hits	15
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

DCP1A_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.021146 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

EPN2_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.032912 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

ATX1_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.033090 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	264	Shared Neighborhood Hits	9
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CBP_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.033174 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	941	Shared Neighborhood Hits	20
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

COKA1_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.015179 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	403	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

NRX2A_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.014609 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	614	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.020936 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	481	Shared Neighborhood Hits	11
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

CBP_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.027533 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	1051	Shared Neighborhood Hits	22
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CU058_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.053891 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P58505	Gene names	C21orf58
Domain Architecture	No domain graphic available
Description	Protein C21orf58.

EPN1_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.030820 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	206	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

HEY1_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.027761 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

I11RB_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.020821 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

ATX1_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.030620 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

CJ047_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.014710 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	164	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

ERN2_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.000131 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	825	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2E3	Gene names	Ern2, Ire2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) (mIre1) [Includes: Serine/threonine- protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

I11RA_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.019509 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

TNR8_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.012457 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

UST_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.019655 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUB6	Gene names	Ust
Domain Architecture	No domain graphic available
Description	Uronyl 2-sulfotransferase (EC 2.8.2.-).

AFF2_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.008671 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

GAW2_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.022770 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRZ4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-W_3q26.32 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein (Gag P15); Capsid protein (Core shell protein) (Gag P30)].

MGRN1_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.019674 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

NACAM_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.010551 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	1866	Shared Neighborhood Hits	31
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TIG2_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.026982 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DD06, Q8CHU8	Gene names	Rarres2
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor responder protein 2 precursor.

TNAP2_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.011656 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q03169, Q86VI0	Gene names	TNFAIP2
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 2 (Primary response gene B94 protein).

CABL2_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.008622 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CF142_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.017692 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FW52, Q9D6X9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf142 homolog.

IL3B2_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.017999 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	372	Shared Neighborhood Hits	14
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

NCOA2_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.008396 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	281	Shared Neighborhood Hits	7
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NOTC1_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.001331 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	916	Shared Neighborhood Hits	8
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PER2_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.009333 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

SON_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.020471 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	1568	Shared Neighborhood Hits	25
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CUED1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.025372 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NWM3, Q9NWD0	Gene names	CUEDC1
Domain Architecture
Description	CUE domain-containing protein 1.

EPN1_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.027933 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	16
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

IL3RB_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.018348 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	355	Shared Neighborhood Hits	12
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

KLF5_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.000142 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	726	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0Z7, Q9JMI2	Gene names	Klf5, Bteb2, Iklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 5 (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) (Basic transcription element-binding protein 2) (BTE-binding protein 2).

LASS6_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.006917 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMG9, Q8N617	Gene names	LASS6
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 6.

LASS6_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.006930 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C172, Q3U817, Q8BV12	Gene names	Lass6
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 6.

LGMN_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.015350 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q99538, O00123	Gene names	LGMN, PRSC1
Domain Architecture
Description	Legumain precursor (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1).

LSR_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.007963 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

WWC1_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.004289 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

ZSWM5_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.010575 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TC6	Gene names	Zswim5, Kiaa1511
Domain Architecture	No domain graphic available
Description	Zinc finger SWIM domain-containing protein 5.

Hits sorted by NC score

PIAS3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_HUMAN
NC score	0.997174 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS1_HUMAN
NC score	0.986316 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

PIAS1_MOUSE
NC score	0.986282 (rank : 4)	θ value	1.90044e-183 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

PIAS2_MOUSE
NC score	0.985734 (rank : 5)	θ value	4.70271e-166 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C5D8, O54987, Q8C384, Q8CDQ8, Q8K208, Q99JX5, Q9D5W7, Q9QZ63	Gene names	Pias2, Miz1, Piasx
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3).

PIAS2_HUMAN
NC score	0.985690 (rank : 6)	θ value	4.70271e-166 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	O75928, O75927, Q96BT5, Q96KE3	Gene names	PIAS2, PIASX
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (Miz1) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) (PIAS-NY protein).

PIAS4_HUMAN
NC score	0.973768 (rank : 7)	θ value	3.09092e-117 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

PIAS4_MOUSE
NC score	0.973583 (rank : 8)	θ value	2.2151e-115 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JM05, Q8R165	Gene names	Pias4, Piasg
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

ZIMP7_HUMAN
NC score	0.566733 (rank : 9)	θ value	2.60593e-15 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIM10_MOUSE
NC score	0.526641 (rank : 10)	θ value	1.24977e-17 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	430	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIMP7_MOUSE
NC score	0.509692 (rank : 11)	θ value	3.40345e-15 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	566	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIM10_HUMAN
NC score	0.487379 (rank : 12)	θ value	7.32683e-18 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	577	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

FBX7_HUMAN
NC score	0.085913 (rank : 13)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3I1, Q5TGC4, Q96HM6, Q9UF21, Q9UKT2	Gene names	FBXO7, FBX7
Domain Architecture	No domain graphic available
Description	F-box only protein 7.

ZN364_MOUSE
NC score	0.054155 (rank : 14)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

CU058_HUMAN
NC score	0.053891 (rank : 15)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P58505	Gene names	C21orf58
Domain Architecture	No domain graphic available
Description	Protein C21orf58.

TENS1_HUMAN
NC score	0.053006 (rank : 16)	θ value	0.00665767 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	400	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

ZN364_HUMAN
NC score	0.050752 (rank : 17)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

CUED1_MOUSE
NC score	0.041871 (rank : 18)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3V6	Gene names	Cuedc1
Domain Architecture
Description	CUE domain-containing protein 1.

HEY1_MOUSE
NC score	0.037961 (rank : 19)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

EPN2_MOUSE
NC score	0.035883 (rank : 20)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

MBD6_HUMAN
NC score	0.034444 (rank : 21)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	349	Shared Neighborhood Hits	15
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

CBP_HUMAN
NC score	0.033174 (rank : 22)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	941	Shared Neighborhood Hits	20
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ATX1_MOUSE
NC score	0.033090 (rank : 23)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	264	Shared Neighborhood Hits	9
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

EPN2_HUMAN
NC score	0.032912 (rank : 24)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

EPN1_HUMAN
NC score	0.030820 (rank : 25)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	206	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

ATX1_HUMAN
NC score	0.030620 (rank : 26)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

EPN1_MOUSE
NC score	0.027933 (rank : 27)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	16
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

HEY1_HUMAN
NC score	0.027761 (rank : 28)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

CBP_MOUSE
NC score	0.027533 (rank : 29)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	1051	Shared Neighborhood Hits	22
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TIG2_MOUSE
NC score	0.026982 (rank : 30)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DD06, Q8CHU8	Gene names	Rarres2
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor responder protein 2 precursor.

CCD1A_HUMAN
NC score	0.025698 (rank : 31)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

CUED1_HUMAN
NC score	0.025372 (rank : 32)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NWM3, Q9NWD0	Gene names	CUEDC1
Domain Architecture
Description	CUE domain-containing protein 1.

GAW2_HUMAN
NC score	0.022770 (rank : 33)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRZ4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-W_3q26.32 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein (Gag P15); Capsid protein (Core shell protein) (Gag P30)].

DCP1A_MOUSE
NC score	0.021146 (rank : 34)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

NRX2B_HUMAN
NC score	0.020936 (rank : 35)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	481	Shared Neighborhood Hits	11
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

I11RB_MOUSE
NC score	0.020821 (rank : 36)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

SON_HUMAN
NC score	0.020471 (rank : 37)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	1568	Shared Neighborhood Hits	25
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MGRN1_HUMAN
NC score	0.019674 (rank : 38)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

UST_MOUSE
NC score	0.019655 (rank : 39)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUB6	Gene names	Ust
Domain Architecture	No domain graphic available
Description	Uronyl 2-sulfotransferase (EC 2.8.2.-).

I11RA_MOUSE
NC score	0.019509 (rank : 40)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

BRCA1_MOUSE
NC score	0.019082 (rank : 41)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	436	Shared Neighborhood Hits	3
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

IL3RB_MOUSE
NC score	0.018348 (rank : 42)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	355	Shared Neighborhood Hits	12
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IL3B2_MOUSE
NC score	0.017999 (rank : 43)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	372	Shared Neighborhood Hits	14
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

CF142_MOUSE
NC score	0.017692 (rank : 44)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FW52, Q9D6X9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf142 homolog.

LGMN_HUMAN
NC score	0.015350 (rank : 45)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q99538, O00123	Gene names	LGMN, PRSC1
Domain Architecture
Description	Legumain precursor (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1).

COKA1_HUMAN
NC score	0.015179 (rank : 46)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	403	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CJ047_HUMAN
NC score	0.014710 (rank : 47)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	164	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

NRX2A_HUMAN
NC score	0.014609 (rank : 48)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	614	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

TNR8_MOUSE
NC score	0.012457 (rank : 49)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNAP2_HUMAN
NC score	0.011656 (rank : 50)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q03169, Q86VI0	Gene names	TNFAIP2
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 2 (Primary response gene B94 protein).

ZSWM5_MOUSE
NC score	0.010575 (rank : 51)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TC6	Gene names	Zswim5, Kiaa1511
Domain Architecture	No domain graphic available
Description	Zinc finger SWIM domain-containing protein 5.

NACAM_MOUSE
NC score	0.010551 (rank : 52)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	1866	Shared Neighborhood Hits	31
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PER2_MOUSE
NC score	0.009333 (rank : 53)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

AFF2_MOUSE
NC score	0.008671 (rank : 54)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

CABL2_HUMAN
NC score	0.008622 (rank : 55)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

NCOA2_MOUSE
NC score	0.008396 (rank : 56)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	281	Shared Neighborhood Hits	7
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

LSR_HUMAN
NC score	0.007963 (rank : 57)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

CSKI1_MOUSE
NC score	0.007254 (rank : 58)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	1031	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LASS6_MOUSE
NC score	0.006930 (rank : 59)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C172, Q3U817, Q8BV12	Gene names	Lass6
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 6.

LASS6_HUMAN
NC score	0.006917 (rank : 60)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMG9, Q8N617	Gene names	LASS6
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 6.

BC11B_MOUSE
NC score	0.006095 (rank : 61)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	767	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

WWC1_MOUSE
NC score	0.004289 (rank : 62)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

NOTC1_MOUSE
NC score	0.001331 (rank : 63)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	916	Shared Neighborhood Hits	8
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KLF5_MOUSE
NC score	0.000142 (rank : 64)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	726	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0Z7, Q9JMI2	Gene names	Klf5, Bteb2, Iklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 5 (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) (Basic transcription element-binding protein 2) (BTE-binding protein 2).

ERN2_MOUSE
NC score	0.000131 (rank : 65)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	825	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2E3	Gene names	Ern2, Ire2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) (mIre1) [Includes: Serine/threonine- protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].