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Network neighborhood for query Sequence : CUED1_MOUSE

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CUED1_MOUSE
SwissProt Accessions	Q8R3V6	Gene names	Cuedc1
Domain Architecture
Description	CUE domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CUED1_MOUSE
θ value	1.78703e-165 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3V6	Gene names	Cuedc1
Domain Architecture
Description	CUE domain-containing protein 1.

CUED1_HUMAN
θ value	2.2711e-144 (rank : 2)	NC score	0.992411 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NWM3, Q9NWD0	Gene names	CUEDC1
Domain Architecture
Description	CUE domain-containing protein 1.

TOLIP_HUMAN
θ value	0.0113563 (rank : 3)	NC score	0.225295 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

TOLIP_MOUSE
θ value	0.0113563 (rank : 4)	NC score	0.222234 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

DLG5_HUMAN
θ value	0.279714 (rank : 5)	NC score	0.027723 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	1088	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

MEF2B_MOUSE
θ value	0.813845 (rank : 6)	NC score	0.042204 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

PIAS3_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.041957 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_MOUSE
θ value	1.38821 (rank : 8)	NC score	0.041871 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

ACM3_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.006435 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	931	Shared Neighborhood Hits	2
SwissProt Accessions	P20309, Q4QRI3, Q5VXY2, Q9HB60	Gene names	CHRM3
Domain Architecture
Description	Muscarinic acetylcholine receptor M3.

MN1_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.037909 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

HAX1_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.034243 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	O35387	Gene names	Hax1, Hs1bp1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

NSF1C_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.026845 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

AFF2_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.018628 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

MLL3_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.011787 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	1644	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

OBSCN_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.002994 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	1931	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

JADE2_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.010890 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

MACF1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.009036 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1341	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.010619 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	1321	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MINP1_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.021935 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2L6, Q8VDR0, Q9JJD5	Gene names	Minpp1, Mipp
Domain Architecture	No domain graphic available
Description	Multiple inositol polyphosphate phosphatase 1 precursor (EC 3.1.3.62) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase).

PTPRK_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.005530 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

AUTS2_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.017860 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

Hits sorted by NC score

CUED1_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.78703e-165 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3V6	Gene names	Cuedc1
Domain Architecture
Description	CUE domain-containing protein 1.

CUED1_HUMAN
NC score	0.992411 (rank : 2)	θ value	2.2711e-144 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NWM3, Q9NWD0	Gene names	CUEDC1
Domain Architecture
Description	CUE domain-containing protein 1.

TOLIP_HUMAN
NC score	0.225295 (rank : 3)	θ value	0.0113563 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

TOLIP_MOUSE
NC score	0.222234 (rank : 4)	θ value	0.0113563 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

MEF2B_MOUSE
NC score	0.042204 (rank : 5)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

PIAS3_HUMAN
NC score	0.041957 (rank : 6)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_MOUSE
NC score	0.041871 (rank : 7)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

MN1_HUMAN
NC score	0.037909 (rank : 8)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

HAX1_MOUSE
NC score	0.034243 (rank : 9)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	O35387	Gene names	Hax1, Hs1bp1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

DLG5_HUMAN
NC score	0.027723 (rank : 10)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	1088	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

NSF1C_MOUSE
NC score	0.026845 (rank : 11)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

MINP1_MOUSE
NC score	0.021935 (rank : 12)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2L6, Q8VDR0, Q9JJD5	Gene names	Minpp1, Mipp
Domain Architecture	No domain graphic available
Description	Multiple inositol polyphosphate phosphatase 1 precursor (EC 3.1.3.62) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase).

AFF2_HUMAN
NC score	0.018628 (rank : 13)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

AUTS2_HUMAN
NC score	0.017860 (rank : 14)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

MLL3_HUMAN
NC score	0.011787 (rank : 15)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	1644	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

JADE2_HUMAN
NC score	0.010890 (rank : 16)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

MACF4_HUMAN
NC score	0.010619 (rank : 17)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1321	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.009036 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	1341	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

ACM3_HUMAN
NC score	0.006435 (rank : 19)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	931	Shared Neighborhood Hits	2
SwissProt Accessions	P20309, Q4QRI3, Q5VXY2, Q9HB60	Gene names	CHRM3
Domain Architecture
Description	Muscarinic acetylcholine receptor M3.

PTPRK_MOUSE
NC score	0.005530 (rank : 20)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

OBSCN_HUMAN
NC score	0.002994 (rank : 21)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	1931	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).