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Network neighborhood for query Sequence : PIAS4_HUMAN

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PIAS4_HUMAN
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PIAS4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

PIAS4_MOUSE
θ value	0 (rank : 2)	NC score	0.998548 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM05, Q8R165	Gene names	Pias4, Piasg
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

PIAS1_MOUSE
θ value	5.63297e-119 (rank : 3)	NC score	0.976410 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

PIAS1_HUMAN
θ value	1.2549e-118 (rank : 4)	NC score	0.975959 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

PIAS3_HUMAN
θ value	6.228e-118 (rank : 5)	NC score	0.974818 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_MOUSE
θ value	3.09092e-117 (rank : 6)	NC score	0.973768 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS2_MOUSE
θ value	5.10665e-112 (rank : 7)	NC score	0.977753 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C5D8, O54987, Q8C384, Q8CDQ8, Q8K208, Q99JX5, Q9D5W7, Q9QZ63	Gene names	Pias2, Miz1, Piasx
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3).

PIAS2_HUMAN
θ value	1.48581e-111 (rank : 8)	NC score	0.977604 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O75928, O75927, Q96BT5, Q96KE3	Gene names	PIAS2, PIASX
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (Miz1) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) (PIAS-NY protein).

ZIMP7_MOUSE
θ value	1.24977e-17 (rank : 9)	NC score	0.529971 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	566	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIM10_HUMAN
θ value	2.13179e-17 (rank : 10)	NC score	0.505819 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_MOUSE
θ value	2.13179e-17 (rank : 11)	NC score	0.546863 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	430	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIMP7_HUMAN
θ value	2.7842e-17 (rank : 12)	NC score	0.590628 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

JHD2B_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.017729 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

STAB2_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.006109 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	534	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

MGRN1_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.022356 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

CBP_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.026180 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	941	Shared Neighborhood Hits	12
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RN125_MOUSE
θ value	4.03905 (rank : 17)	NC score	0.008627 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

ARHG1_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.007356 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

NASP_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.006499 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	709	Shared Neighborhood Hits	4
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

FOXP3_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.003201 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q99JB6	Gene names	Foxp3
Domain Architecture
Description	Forkhead box protein P3 (Scurfin).

LRIG2_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.000743 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	586	Shared Neighborhood Hits	3
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

ZN409_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.002331 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	842	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

Hits sorted by NC score

PIAS4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

PIAS4_MOUSE
NC score	0.998548 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM05, Q8R165	Gene names	Pias4, Piasg
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

PIAS2_MOUSE
NC score	0.977753 (rank : 3)	θ value	5.10665e-112 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C5D8, O54987, Q8C384, Q8CDQ8, Q8K208, Q99JX5, Q9D5W7, Q9QZ63	Gene names	Pias2, Miz1, Piasx
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3).

PIAS2_HUMAN
NC score	0.977604 (rank : 4)	θ value	1.48581e-111 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O75928, O75927, Q96BT5, Q96KE3	Gene names	PIAS2, PIASX
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (Miz1) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) (PIAS-NY protein).

PIAS1_MOUSE
NC score	0.976410 (rank : 5)	θ value	5.63297e-119 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

PIAS1_HUMAN
NC score	0.975959 (rank : 6)	θ value	1.2549e-118 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

PIAS3_HUMAN
NC score	0.974818 (rank : 7)	θ value	6.228e-118 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_MOUSE
NC score	0.973768 (rank : 8)	θ value	3.09092e-117 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

ZIMP7_HUMAN
NC score	0.590628 (rank : 9)	θ value	2.7842e-17 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIM10_MOUSE
NC score	0.546863 (rank : 10)	θ value	2.13179e-17 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	430	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIMP7_MOUSE
NC score	0.529971 (rank : 11)	θ value	1.24977e-17 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	566	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIM10_HUMAN
NC score	0.505819 (rank : 12)	θ value	2.13179e-17 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CBP_HUMAN
NC score	0.026180 (rank : 13)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	941	Shared Neighborhood Hits	12
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MGRN1_HUMAN
NC score	0.022356 (rank : 14)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

JHD2B_HUMAN
NC score	0.017729 (rank : 15)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

RN125_MOUSE
NC score	0.008627 (rank : 16)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

ARHG1_MOUSE
NC score	0.007356 (rank : 17)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

NASP_HUMAN
NC score	0.006499 (rank : 18)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	709	Shared Neighborhood Hits	4
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

STAB2_HUMAN
NC score	0.006109 (rank : 19)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	534	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

FOXP3_MOUSE
NC score	0.003201 (rank : 20)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q99JB6	Gene names	Foxp3
Domain Architecture
Description	Forkhead box protein P3 (Scurfin).

ZN409_HUMAN
NC score	0.002331 (rank : 21)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	842	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

LRIG2_MOUSE
NC score	0.000743 (rank : 22)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	586	Shared Neighborhood Hits	3
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.