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Network neighborhood for query Sequence : FBX7_HUMAN

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FBX7_HUMAN
SwissProt Accessions	Q9Y3I1, Q5TGC4, Q96HM6, Q9UF21, Q9UKT2	Gene names	FBXO7, FBX7
Domain Architecture	No domain graphic available
Description	F-box only protein 7.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBX7_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3I1, Q5TGC4, Q96HM6, Q9UF21, Q9UKT2	Gene names	FBXO7, FBX7
Domain Architecture	No domain graphic available
Description	F-box only protein 7.

FBX9_HUMAN
θ value	1.09739e-05 (rank : 2)	NC score	0.305362 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UK97, O75986, Q6PKH7, Q9NT57, Q9Y593	Gene names	FBXO9, FBX9, VCIA1
Domain Architecture	No domain graphic available
Description	F-box only protein 9 (NY-REN-57 antigen) (Cross-immune reaction antigen 1).

FBX9_MOUSE
θ value	0.000158464 (rank : 3)	NC score	0.290968 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BK06, Q8VDY6, Q9D349, Q9JJC5	Gene names	Fbxo9
Domain Architecture	No domain graphic available
Description	F-box only protein 9.

FBXW5_MOUSE
θ value	0.0431538 (rank : 4)	NC score	0.124501 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	159	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBX11_HUMAN
θ value	0.0563607 (rank : 5)	NC score	0.144990 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

PIAS3_HUMAN
θ value	0.0563607 (rank : 6)	NC score	0.086015 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_MOUSE
θ value	0.0563607 (rank : 7)	NC score	0.085913 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

LRIG2_HUMAN
θ value	0.21417 (rank : 8)	NC score	0.024947 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	595	Shared Neighborhood Hits	5
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

SMOO_HUMAN
θ value	0.21417 (rank : 9)	NC score	0.052561 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	391	Shared Neighborhood Hits	5
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SSBP4_HUMAN
θ value	0.279714 (rank : 10)	NC score	0.045266 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	753	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

LCP2_HUMAN
θ value	0.47712 (rank : 11)	NC score	0.052708 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	531	Shared Neighborhood Hits	14
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

TCRG1_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.043293 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	929	Shared Neighborhood Hits	12
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

DSPP_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.051482 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	645	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

AP2B_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.060101 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.060041 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

BAZ2B_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.035092 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	803	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

FBX15_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.094316 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBX4_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.100959 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKT5, Q68CU8, Q86VT8, Q9UK98	Gene names	FBXO4, FBX4
Domain Architecture
Description	F-box only protein 4.

NRK_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.010044 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	899	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

FBX4_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.097836 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHQ0, Q99JG8	Gene names	Fbxo4, Fbx4
Domain Architecture	No domain graphic available
Description	F-box only protein 4.

FBXW5_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.105719 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

PSMF1_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.065763 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

RBBP6_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.049673 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.052192 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	1014	Shared Neighborhood Hits	11
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

BCL7A_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.068414 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

FBX41_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.062219 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	475	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.062507 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	430	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FXL22_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.070583 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P050	Gene names	FBXL22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

BCL7A_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.064921 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

FBXW7_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.033962 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	433	Shared Neighborhood Hits	18
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.033756 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	365	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FMN2_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.029254 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	484	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

RIN3_MOUSE
θ value	2.36792 (rank : 33)	NC score	0.033733 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	239	Shared Neighborhood Hits	6
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ROBO2_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.018084 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	504	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SKP2_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.062920 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

SSXT_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.053407 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

ENAM_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.039415 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

FBX15_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.079767 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZN0	Gene names	Fbxo15, Fbx15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FOG2_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.014314 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	714	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

SCN5A_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.013246 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	145	Shared Neighborhood Hits	2
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

BLM_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.029216 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

CBP_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.034902 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	941	Shared Neighborhood Hits	19
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FOXN1_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.020150 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

LRIG1_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.017603 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	627	Shared Neighborhood Hits	5
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

SKP2_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.058532 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

BLM_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.029389 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

FBW1A_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.021758 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	329	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

HPS4_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.031118 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

PALB2_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.028255 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

SSXT_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.046288 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

TESK1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.003661 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	864	Shared Neighborhood Hits	4
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

ZDHC1_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.019714 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

ZN366_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.000857 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	732	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.

ACM2_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.002861 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	930	Shared Neighborhood Hits	3
SwissProt Accessions	P08172, Q9P1X9	Gene names	CHRM2
Domain Architecture
Description	Muscarinic acetylcholine receptor M2.

ADA29_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.007254 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

CA026_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.026719 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

CPSF6_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.037050 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	359	Shared Neighborhood Hits	11
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.037045 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	356	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

DSPP_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.037137 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	491	Shared Neighborhood Hits	7
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FOXI1_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.014200 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q12951, Q14518, Q66SR7, Q8N6L8	Gene names	FOXI1, FKHL10, FREAC6
Domain Architecture
Description	Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead- related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HNF-3/fork-head homolog 3) (HFH-3).

FOXI1_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.014205 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q922I5, Q5SRI5, Q9D299	Gene names	Foxi1
Domain Architecture	No domain graphic available
Description	Forkhead box protein I1.

I17RA_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.022153 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q60943	Gene names	IL17ra, Il17r
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

SMAL1_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.015226 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

CBP_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.032689 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	1051	Shared Neighborhood Hits	24
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

F120C_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.016444 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

FXL12_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.041444 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	86	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

NCOA6_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.028201 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	1202	Shared Neighborhood Hits	20
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.028778 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	1076	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NU160_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.018618 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q12769, Q96GB3, Q9H660	Gene names	NUP160, KIAA0197, NUP120
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup160 (Nucleoporin Nup160) (160 kDa nucleoporin).

PTN23_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.010461 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	726	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

ROBO1_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.015316 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	559	Shared Neighborhood Hits	5
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

TCAL3_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.014502 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

Hits sorted by NC score

FBX7_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3I1, Q5TGC4, Q96HM6, Q9UF21, Q9UKT2	Gene names	FBXO7, FBX7
Domain Architecture	No domain graphic available
Description	F-box only protein 7.

FBX9_HUMAN
NC score	0.305362 (rank : 2)	θ value	1.09739e-05 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UK97, O75986, Q6PKH7, Q9NT57, Q9Y593	Gene names	FBXO9, FBX9, VCIA1
Domain Architecture	No domain graphic available
Description	F-box only protein 9 (NY-REN-57 antigen) (Cross-immune reaction antigen 1).

FBX9_MOUSE
NC score	0.290968 (rank : 3)	θ value	0.000158464 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BK06, Q8VDY6, Q9D349, Q9JJC5	Gene names	Fbxo9
Domain Architecture	No domain graphic available
Description	F-box only protein 9.

FBX11_HUMAN
NC score	0.144990 (rank : 4)	θ value	0.0563607 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FBXW5_MOUSE
NC score	0.124501 (rank : 5)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	159	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBXW5_HUMAN
NC score	0.105719 (rank : 6)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBX4_HUMAN
NC score	0.100959 (rank : 7)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKT5, Q68CU8, Q86VT8, Q9UK98	Gene names	FBXO4, FBX4
Domain Architecture
Description	F-box only protein 4.

FBX4_MOUSE
NC score	0.097836 (rank : 8)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHQ0, Q99JG8	Gene names	Fbxo4, Fbx4
Domain Architecture	No domain graphic available
Description	F-box only protein 4.

FBX15_HUMAN
NC score	0.094316 (rank : 9)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

PIAS3_HUMAN
NC score	0.086015 (rank : 10)	θ value	0.0563607 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PIAS3_MOUSE
NC score	0.085913 (rank : 11)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

FBX15_MOUSE
NC score	0.079767 (rank : 12)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZN0	Gene names	Fbxo15, Fbx15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FXL22_HUMAN
NC score	0.070583 (rank : 13)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P050	Gene names	FBXL22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

BCL7A_HUMAN
NC score	0.068414 (rank : 14)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

PSMF1_MOUSE
NC score	0.065763 (rank : 15)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

BCL7A_MOUSE
NC score	0.064921 (rank : 16)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

SKP2_HUMAN
NC score	0.062920 (rank : 17)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

FBX41_MOUSE
NC score	0.062507 (rank : 18)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	430	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_HUMAN
NC score	0.062219 (rank : 19)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	475	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

AP2B_HUMAN
NC score	0.060101 (rank : 20)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
NC score	0.060041 (rank : 21)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

SKP2_MOUSE
NC score	0.058532 (rank : 22)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

SSXT_MOUSE
NC score	0.053407 (rank : 23)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

LCP2_HUMAN
NC score	0.052708 (rank : 24)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	531	Shared Neighborhood Hits	14
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SMOO_HUMAN
NC score	0.052561 (rank : 25)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	391	Shared Neighborhood Hits	5
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

RBBP6_MOUSE
NC score	0.052192 (rank : 26)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	1014	Shared Neighborhood Hits	11
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

DSPP_HUMAN
NC score	0.051482 (rank : 27)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	645	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RBBP6_HUMAN
NC score	0.049673 (rank : 28)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SSXT_HUMAN
NC score	0.046288 (rank : 29)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

SSBP4_HUMAN
NC score	0.045266 (rank : 30)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	753	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TCRG1_HUMAN
NC score	0.043293 (rank : 31)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	929	Shared Neighborhood Hits	12
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

FXL12_HUMAN
NC score	0.041444 (rank : 32)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	86	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

ENAM_HUMAN
NC score	0.039415 (rank : 33)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

DSPP_MOUSE
NC score	0.037137 (rank : 34)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	491	Shared Neighborhood Hits	7
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CPSF6_HUMAN
NC score	0.037050 (rank : 35)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	359	Shared Neighborhood Hits	11
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
NC score	0.037045 (rank : 36)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	356	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

BAZ2B_HUMAN
NC score	0.035092 (rank : 37)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	803	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CBP_HUMAN
NC score	0.034902 (rank : 38)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	941	Shared Neighborhood Hits	19
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FBXW7_HUMAN
NC score	0.033962 (rank : 39)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	433	Shared Neighborhood Hits	18
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
NC score	0.033756 (rank : 40)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	365	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

RIN3_MOUSE
NC score	0.033733 (rank : 41)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	239	Shared Neighborhood Hits	6
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

CBP_MOUSE
NC score	0.032689 (rank : 42)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	1051	Shared Neighborhood Hits	24
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

HPS4_MOUSE
NC score	0.031118 (rank : 43)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

BLM_HUMAN
NC score	0.029389 (rank : 44)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

FMN2_HUMAN
NC score	0.029254 (rank : 45)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	484	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

BLM_MOUSE
NC score	0.029216 (rank : 46)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

NCOA6_MOUSE
NC score	0.028778 (rank : 47)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	1076	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PALB2_MOUSE
NC score	0.028255 (rank : 48)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

NCOA6_HUMAN
NC score	0.028201 (rank : 49)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	1202	Shared Neighborhood Hits	20
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CA026_MOUSE
NC score	0.026719 (rank : 50)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

LRIG2_HUMAN
NC score	0.024947 (rank : 51)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	595	Shared Neighborhood Hits	5
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

I17RA_MOUSE
NC score	0.022153 (rank : 52)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q60943	Gene names	IL17ra, Il17r
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

FBW1A_HUMAN
NC score	0.021758 (rank : 53)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	329	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FOXN1_HUMAN
NC score	0.020150 (rank : 54)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

ZDHC1_HUMAN
NC score	0.019714 (rank : 55)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

NU160_HUMAN
NC score	0.018618 (rank : 56)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q12769, Q96GB3, Q9H660	Gene names	NUP160, KIAA0197, NUP120
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup160 (Nucleoporin Nup160) (160 kDa nucleoporin).

ROBO2_MOUSE
NC score	0.018084 (rank : 57)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	504	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

LRIG1_MOUSE
NC score	0.017603 (rank : 58)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	627	Shared Neighborhood Hits	5
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

F120C_MOUSE
NC score	0.016444 (rank : 59)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

ROBO1_MOUSE
NC score	0.015316 (rank : 60)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	559	Shared Neighborhood Hits	5
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

SMAL1_HUMAN
NC score	0.015226 (rank : 61)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

TCAL3_HUMAN
NC score	0.014502 (rank : 62)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

FOG2_MOUSE
NC score	0.014314 (rank : 63)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	714	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

FOXI1_MOUSE
NC score	0.014205 (rank : 64)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q922I5, Q5SRI5, Q9D299	Gene names	Foxi1
Domain Architecture	No domain graphic available
Description	Forkhead box protein I1.

FOXI1_HUMAN
NC score	0.014200 (rank : 65)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q12951, Q14518, Q66SR7, Q8N6L8	Gene names	FOXI1, FKHL10, FREAC6
Domain Architecture
Description	Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead- related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HNF-3/fork-head homolog 3) (HFH-3).

SCN5A_HUMAN
NC score	0.013246 (rank : 66)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	145	Shared Neighborhood Hits	2
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

PTN23_MOUSE
NC score	0.010461 (rank : 67)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	726	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

NRK_MOUSE
NC score	0.010044 (rank : 68)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	899	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

ADA29_HUMAN
NC score	0.007254 (rank : 69)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

TESK1_HUMAN
NC score	0.003661 (rank : 70)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	864	Shared Neighborhood Hits	4
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

ACM2_HUMAN
NC score	0.002861 (rank : 71)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	930	Shared Neighborhood Hits	3
SwissProt Accessions	P08172, Q9P1X9	Gene names	CHRM2
Domain Architecture
Description	Muscarinic acetylcholine receptor M2.

ZN366_HUMAN
NC score	0.000857 (rank : 72)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	732	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.