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Network neighborhood for query Sequence : MDM2_MOUSE

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MDM2_MOUSE
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MDM2_HUMAN
θ value	0 (rank : 1)	NC score	0.975358 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MDM2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

MDM4_HUMAN
θ value	3.36421e-55 (rank : 3)	NC score	0.875077 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MDM4_MOUSE
θ value	4.39379e-55 (rank : 4)	NC score	0.870787 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

NEURL_MOUSE
θ value	0.00665767 (rank : 5)	NC score	0.243313 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NEUL1_HUMAN
θ value	0.00869519 (rank : 6)	NC score	0.239030 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

LEO1_HUMAN
θ value	0.0148317 (rank : 7)	NC score	0.053508 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	958	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RFFL_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.180397 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	0.0736092 (rank : 9)	NC score	0.183963 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

MGRN1_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.168760 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	192	Shared Neighborhood Hits	32
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

BIRC4_MOUSE
θ value	0.125558 (rank : 11)	NC score	0.133010 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	26
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

MGRN1_MOUSE
θ value	0.163984 (rank : 12)	NC score	0.173109 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	149	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

AKAP5_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.076544 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

MIB1_MOUSE
θ value	0.21417 (rank : 14)	NC score	0.066393 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	471	Shared Neighborhood Hits	31
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RNF34_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.189825 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	153	Shared Neighborhood Hits	30
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	0.279714 (rank : 16)	NC score	0.192011 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	160	Shared Neighborhood Hits	32
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

BIRC2_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.145255 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	137	Shared Neighborhood Hits	28
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.147158 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	133	Shared Neighborhood Hits	28
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.142655 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	28
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

CHFR_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.069035 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	264	Shared Neighborhood Hits	21
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN103_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.060158 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	153	Shared Neighborhood Hits	12
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

MIB1_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.065159 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	470	Shared Neighborhood Hits	31
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MAP1B_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.037175 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	977	Shared Neighborhood Hits	16
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RNF8_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.050945 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	618	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SPRL1_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.036486 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

FXL19_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.032415 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

NCOR1_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.036783 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	521	Shared Neighborhood Hits	10
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

TOPRS_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.090977 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	263	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

BIRC2_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.129310 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

CLGN_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.023424 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

DDX27_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.010554 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

OXRP_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.017622 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	544	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

TTBK1_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.010488 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	1058	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

BRD7_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.023693 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

LEO1_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.047894 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	946	Shared Neighborhood Hits	22
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

BIRC4_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.119759 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	27
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BRD8_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.027331 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	422	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

EP15_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.010273 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	1021	Shared Neighborhood Hits	9
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

JIP1_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.022228 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

CM007_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.033686 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	416	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

GLI3_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.002022 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	871	Shared Neighborhood Hits	5
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

LIRB3_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.009399 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

NCOR1_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.034881 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	577	Shared Neighborhood Hits	15
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

TOPRS_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.072070 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

BIRC5_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.053173 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

CJ078_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.021479 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	559	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

FXL19_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.027923 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	147	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

LRSM1_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.051395 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	1078	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MLL3_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.010340 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	1644	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NASP_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.027931 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	709	Shared Neighborhood Hits	15
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

RN103_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.049545 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	143	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

YTDC1_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.030404 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	458	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZN330_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.024084 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

AN30A_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.009932 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	1119	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CIC_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.015433 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	992	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.017313 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	742	Shared Neighborhood Hits	10
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ACHA6_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.007566 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q15825	Gene names	CHRNA6
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-6 precursor.

ALO17_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.022449 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	317	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ELOA1_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.014456 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	388	Shared Neighborhood Hits	9
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

FOXB1_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.004835 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q99853, O60652, O75917	Gene names	FOXB1, FKH5
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

IWS1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.023515 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LRSM1_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.053715 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	874	Shared Neighborhood Hits	33
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MAP1B_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.033936 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	903	Shared Neighborhood Hits	19
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MIA2_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.017830 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

NPL4_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.016020 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

PTPRZ_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.005341 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

RNF8_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.046102 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	622	Shared Neighborhood Hits	28
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

STON2_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.013513 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

BIRC7_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.097307 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	185	Shared Neighborhood Hits	29
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CF103_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.017109 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

CGRF1_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.082615 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

F16P1_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.010617 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXD6, Q3UEH1	Gene names	Fbp1, Fbp
Domain Architecture
Description	Fructose-1,6-bisphosphatase 1 (EC 3.1.3.11) (D-fructose-1,6- bisphosphate 1-phosphohydrolase 1) (FBPase 1).

RANB3_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.013107 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

SAKS1_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.011300 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

TRI26_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.022818 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	335	Shared Neighborhood Hits	31
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

ZAN_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.003675 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	808	Shared Neighborhood Hits	5
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZN507_HUMAN
θ value	8.99809 (rank : 77)	NC score	-0.000186 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	739	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

BIRC8_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.092103 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CGRF1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.069316 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

MYLIP_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.051369 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RKHD1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.067765 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RNF26_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.081598 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

Hits sorted by NC score

MDM2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

MDM2_HUMAN
NC score	0.975358 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MDM4_HUMAN
NC score	0.875077 (rank : 3)	θ value	3.36421e-55 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MDM4_MOUSE
NC score	0.870787 (rank : 4)	θ value	4.39379e-55 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

NEURL_MOUSE
NC score	0.243313 (rank : 5)	θ value	0.00665767 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NEUL1_HUMAN
NC score	0.239030 (rank : 6)	θ value	0.00869519 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

RNF34_MOUSE
NC score	0.192011 (rank : 7)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	160	Shared Neighborhood Hits	32
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.189825 (rank : 8)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	153	Shared Neighborhood Hits	30
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RFFL_MOUSE
NC score	0.183963 (rank : 9)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
NC score	0.180397 (rank : 10)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

MGRN1_MOUSE
NC score	0.173109 (rank : 11)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	149	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MGRN1_HUMAN
NC score	0.168760 (rank : 12)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	192	Shared Neighborhood Hits	32
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

BIRC3_HUMAN
NC score	0.147158 (rank : 13)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	133	Shared Neighborhood Hits	28
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC2_MOUSE
NC score	0.145255 (rank : 14)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	137	Shared Neighborhood Hits	28
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_MOUSE
NC score	0.142655 (rank : 15)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	28
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC4_MOUSE
NC score	0.133010 (rank : 16)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	26
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC2_HUMAN
NC score	0.129310 (rank : 17)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC4_HUMAN
NC score	0.119759 (rank : 18)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	27
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC7_HUMAN
NC score	0.097307 (rank : 19)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	185	Shared Neighborhood Hits	29
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC8_HUMAN
NC score	0.092103 (rank : 20)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

TOPRS_MOUSE
NC score	0.090977 (rank : 21)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	263	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CGRF1_MOUSE
NC score	0.082615 (rank : 22)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

RNF26_HUMAN
NC score	0.081598 (rank : 23)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

AKAP5_HUMAN
NC score	0.076544 (rank : 24)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

TOPRS_HUMAN
NC score	0.072070 (rank : 25)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CGRF1_HUMAN
NC score	0.069316 (rank : 26)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CHFR_MOUSE
NC score	0.069035 (rank : 27)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	264	Shared Neighborhood Hits	21
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RKHD1_HUMAN
NC score	0.067765 (rank : 28)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

MIB1_MOUSE
NC score	0.066393 (rank : 29)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	471	Shared Neighborhood Hits	31
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB1_HUMAN
NC score	0.065159 (rank : 30)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	470	Shared Neighborhood Hits	31
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

RN103_HUMAN
NC score	0.060158 (rank : 31)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	153	Shared Neighborhood Hits	12
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

LRSM1_MOUSE
NC score	0.053715 (rank : 32)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	874	Shared Neighborhood Hits	33
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

LEO1_HUMAN
NC score	0.053508 (rank : 33)	θ value	0.0148317 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	958	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

BIRC5_HUMAN
NC score	0.053173 (rank : 34)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

LRSM1_HUMAN
NC score	0.051395 (rank : 35)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	1078	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MYLIP_HUMAN
NC score	0.051369 (rank : 36)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RNF8_MOUSE
NC score	0.050945 (rank : 37)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	618	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RN103_MOUSE
NC score	0.049545 (rank : 38)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	143	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

LEO1_MOUSE
NC score	0.047894 (rank : 39)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	946	Shared Neighborhood Hits	22
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

RNF8_HUMAN
NC score	0.046102 (rank : 40)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	622	Shared Neighborhood Hits	28
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

MAP1B_MOUSE
NC score	0.037175 (rank : 41)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	977	Shared Neighborhood Hits	16
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NCOR1_MOUSE
NC score	0.036783 (rank : 42)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	521	Shared Neighborhood Hits	10
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

SPRL1_HUMAN
NC score	0.036486 (rank : 43)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

NCOR1_HUMAN
NC score	0.034881 (rank : 44)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	577	Shared Neighborhood Hits	15
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

MAP1B_HUMAN
NC score	0.033936 (rank : 45)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	903	Shared Neighborhood Hits	19
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CM007_MOUSE
NC score	0.033686 (rank : 46)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	416	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

FXL19_MOUSE
NC score	0.032415 (rank : 47)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

YTDC1_HUMAN
NC score	0.030404 (rank : 48)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	458	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

NASP_HUMAN
NC score	0.027931 (rank : 49)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	709	Shared Neighborhood Hits	15
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

FXL19_HUMAN
NC score	0.027923 (rank : 50)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	147	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

BRD8_MOUSE
NC score	0.027331 (rank : 51)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	422	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

ZN330_HUMAN
NC score	0.024084 (rank : 52)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

BRD7_HUMAN
NC score	0.023693 (rank : 53)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

IWS1_HUMAN
NC score	0.023515 (rank : 54)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CLGN_HUMAN
NC score	0.023424 (rank : 55)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

TRI26_HUMAN
NC score	0.022818 (rank : 56)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	335	Shared Neighborhood Hits	31
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

ALO17_HUMAN
NC score	0.022449 (rank : 57)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	317	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

JIP1_MOUSE
NC score	0.022228 (rank : 58)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

CJ078_MOUSE
NC score	0.021479 (rank : 59)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	559	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MIA2_MOUSE
NC score	0.017830 (rank : 60)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

OXRP_HUMAN
NC score	0.017622 (rank : 61)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	544	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

CIC_MOUSE
NC score	0.017313 (rank : 62)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	742	Shared Neighborhood Hits	10
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CF103_HUMAN
NC score	0.017109 (rank : 63)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

NPL4_HUMAN
NC score	0.016020 (rank : 64)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

CIC_HUMAN
NC score	0.015433 (rank : 65)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	992	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ELOA1_HUMAN
NC score	0.014456 (rank : 66)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	388	Shared Neighborhood Hits	9
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

STON2_HUMAN
NC score	0.013513 (rank : 67)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

RANB3_MOUSE
NC score	0.013107 (rank : 68)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

SAKS1_MOUSE
NC score	0.011300 (rank : 69)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

F16P1_MOUSE
NC score	0.010617 (rank : 70)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXD6, Q3UEH1	Gene names	Fbp1, Fbp
Domain Architecture
Description	Fructose-1,6-bisphosphatase 1 (EC 3.1.3.11) (D-fructose-1,6- bisphosphate 1-phosphohydrolase 1) (FBPase 1).

DDX27_HUMAN
NC score	0.010554 (rank : 71)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

TTBK1_HUMAN
NC score	0.010488 (rank : 72)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	1058	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

MLL3_HUMAN
NC score	0.010340 (rank : 73)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	1644	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EP15_HUMAN
NC score	0.010273 (rank : 74)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	1021	Shared Neighborhood Hits	9
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

AN30A_HUMAN
NC score	0.009932 (rank : 75)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	1119	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

LIRB3_HUMAN
NC score	0.009399 (rank : 76)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

ACHA6_HUMAN
NC score	0.007566 (rank : 77)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q15825	Gene names	CHRNA6
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-6 precursor.

PTPRZ_HUMAN
NC score	0.005341 (rank : 78)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

FOXB1_HUMAN
NC score	0.004835 (rank : 79)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q99853, O60652, O75917	Gene names	FOXB1, FKH5
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

ZAN_MOUSE
NC score	0.003675 (rank : 80)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	808	Shared Neighborhood Hits	5
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

GLI3_HUMAN
NC score	0.002022 (rank : 81)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	871	Shared Neighborhood Hits	5
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

ZN507_HUMAN
NC score	-0.000186 (rank : 82)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	739	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.