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Network neighborhood for query Sequence : AKAP5_HUMAN

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AKAP5_HUMAN
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AKAP5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

DBF4_HUMAN
θ value	0.00298849 (rank : 2)	NC score	0.156503 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

AKA12_HUMAN
θ value	0.00509761 (rank : 3)	NC score	0.123193 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	825	Shared Neighborhood Hits	14
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

TTK_MOUSE
θ value	0.0330416 (rank : 4)	NC score	0.029045 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	803	Shared Neighborhood Hits	5
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

CD2L7_HUMAN
θ value	0.0736092 (rank : 5)	NC score	0.020415 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	1275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

AFF4_HUMAN
θ value	0.125558 (rank : 6)	NC score	0.067210 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	611	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

DMP1_MOUSE
θ value	0.125558 (rank : 7)	NC score	0.086580 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	498	Shared Neighborhood Hits	12
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

TITIN_HUMAN
θ value	0.125558 (rank : 8)	NC score	0.024994 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	2923	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MDM2_MOUSE
θ value	0.21417 (rank : 9)	NC score	0.076544 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

IWS1_MOUSE
θ value	0.279714 (rank : 10)	NC score	0.061379 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	1258	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

GLU2B_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.075980 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	377	Shared Neighborhood Hits	7
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

CENPE_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.020319 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	2060	Shared Neighborhood Hits	19
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

FA8_MOUSE
θ value	0.62314 (rank : 13)	NC score	0.035465 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

P53_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.079215 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

ARHGG_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.034407 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

KPBB_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.056656 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q93100, Q8N4T5	Gene names	PHKB
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

P53_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.075916 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P02340, Q9QUP3	Gene names	Tp53, P53, Trp53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53).

TPX2_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.074583 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

MATR3_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.039936 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	321	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

SFR15_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.043027 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	368	Shared Neighborhood Hits	6
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

RAE2_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.024821 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P26374, Q9H1Y4	Gene names	CHML, REP2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

AMELX_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.033288 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

CBP_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.032349 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	941	Shared Neighborhood Hits	10
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.030335 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	1051	Shared Neighborhood Hits	9
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

KPBB_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.046746 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TSH2	Gene names	Phkb
Domain Architecture	No domain graphic available
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

MBB1A_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.032659 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	665	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PA24F_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.016662 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

SCG2_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.034608 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	190	Shared Neighborhood Hits	9
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

ANR12_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.016192 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	1081	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ARVC_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.013556 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

CCD11_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.018910 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	822	Shared Neighborhood Hits	9
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CE110_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.027226 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

GSCR2_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.039578 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZM5, Q9BTC6, Q9HAX6, Q9NPP1, Q9NPR4, Q9UFI2	Gene names	GLTSCR2
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 2 protein (p60).

NC6IP_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.030834 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

REST_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.015074 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	1506	Shared Neighborhood Hits	12
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

STX18_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.036860 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

TPR_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.015486 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	1921	Shared Neighborhood Hits	17
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ZN435_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.001194 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	774	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4T2, Q9H6K2	Gene names	ZNF435, ZSCAN16
Domain Architecture
Description	Zinc finger protein 435 (Zinc finger and SCAN domain-containing protein 16).

ANR21_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.011821 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	864	Shared Neighborhood Hits	11
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

LRC46_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.018845 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DAP0, Q8R1Z3	Gene names	Lrrc46
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 46.

TP53B_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.030539 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	413	Shared Neighborhood Hits	10
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DBF4_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.074283 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ41, Q3TQP4, Q3V1K2, Q6NSQ1, Q9CXF2	Gene names	Dbf4
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (MuDBF4).

Hits sorted by NC score

AKAP5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

DBF4_HUMAN
NC score	0.156503 (rank : 2)	θ value	0.00298849 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

AKA12_HUMAN
NC score	0.123193 (rank : 3)	θ value	0.00509761 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	825	Shared Neighborhood Hits	14
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DMP1_MOUSE
NC score	0.086580 (rank : 4)	θ value	0.125558 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	498	Shared Neighborhood Hits	12
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

P53_HUMAN
NC score	0.079215 (rank : 5)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

MDM2_MOUSE
NC score	0.076544 (rank : 6)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

GLU2B_HUMAN
NC score	0.075980 (rank : 7)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	377	Shared Neighborhood Hits	7
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

P53_MOUSE
NC score	0.075916 (rank : 8)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P02340, Q9QUP3	Gene names	Tp53, P53, Trp53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53).

TPX2_HUMAN
NC score	0.074583 (rank : 9)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

DBF4_MOUSE
NC score	0.074283 (rank : 10)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ41, Q3TQP4, Q3V1K2, Q6NSQ1, Q9CXF2	Gene names	Dbf4
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (MuDBF4).

AFF4_HUMAN
NC score	0.067210 (rank : 11)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	611	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

IWS1_MOUSE
NC score	0.061379 (rank : 12)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	1258	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KPBB_HUMAN
NC score	0.056656 (rank : 13)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q93100, Q8N4T5	Gene names	PHKB
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

KPBB_MOUSE
NC score	0.046746 (rank : 14)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TSH2	Gene names	Phkb
Domain Architecture	No domain graphic available
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

SFR15_HUMAN
NC score	0.043027 (rank : 15)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	368	Shared Neighborhood Hits	6
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

MATR3_MOUSE
NC score	0.039936 (rank : 16)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	321	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

GSCR2_HUMAN
NC score	0.039578 (rank : 17)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZM5, Q9BTC6, Q9HAX6, Q9NPP1, Q9NPR4, Q9UFI2	Gene names	GLTSCR2
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 2 protein (p60).

STX18_HUMAN
NC score	0.036860 (rank : 18)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

FA8_MOUSE
NC score	0.035465 (rank : 19)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

SCG2_HUMAN
NC score	0.034608 (rank : 20)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	190	Shared Neighborhood Hits	9
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

ARHGG_MOUSE
NC score	0.034407 (rank : 21)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

AMELX_HUMAN
NC score	0.033288 (rank : 22)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

MBB1A_HUMAN
NC score	0.032659 (rank : 23)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	665	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CBP_HUMAN
NC score	0.032349 (rank : 24)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	941	Shared Neighborhood Hits	10
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NC6IP_HUMAN
NC score	0.030834 (rank : 25)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

TP53B_HUMAN
NC score	0.030539 (rank : 26)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	413	Shared Neighborhood Hits	10
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CBP_MOUSE
NC score	0.030335 (rank : 27)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	1051	Shared Neighborhood Hits	9
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TTK_MOUSE
NC score	0.029045 (rank : 28)	θ value	0.0330416 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	803	Shared Neighborhood Hits	5
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

CE110_HUMAN
NC score	0.027226 (rank : 29)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

TITIN_HUMAN
NC score	0.024994 (rank : 30)	θ value	0.125558 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	2923	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

RAE2_HUMAN
NC score	0.024821 (rank : 31)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P26374, Q9H1Y4	Gene names	CHML, REP2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

CD2L7_HUMAN
NC score	0.020415 (rank : 32)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	1275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CENPE_HUMAN
NC score	0.020319 (rank : 33)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	2060	Shared Neighborhood Hits	19
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CCD11_HUMAN
NC score	0.018910 (rank : 34)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	822	Shared Neighborhood Hits	9
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

LRC46_MOUSE
NC score	0.018845 (rank : 35)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DAP0, Q8R1Z3	Gene names	Lrrc46
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 46.

PA24F_MOUSE
NC score	0.016662 (rank : 36)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

ANR12_HUMAN
NC score	0.016192 (rank : 37)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	1081	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

TPR_HUMAN
NC score	0.015486 (rank : 38)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	1921	Shared Neighborhood Hits	17
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

REST_MOUSE
NC score	0.015074 (rank : 39)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	1506	Shared Neighborhood Hits	12
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ARVC_HUMAN
NC score	0.013556 (rank : 40)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ANR21_HUMAN
NC score	0.011821 (rank : 41)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	864	Shared Neighborhood Hits	11
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ZN435_HUMAN
NC score	0.001194 (rank : 42)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	774	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4T2, Q9H6K2	Gene names	ZNF435, ZSCAN16
Domain Architecture
Description	Zinc finger protein 435 (Zinc finger and SCAN domain-containing protein 16).