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Network neighborhood for query Sequence : CF103_HUMAN

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CF103_HUMAN
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CF103_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

CAN7_MOUSE
θ value	1.58096e-12 (rank : 2)	NC score	0.408132 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	66	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1S8, Q9Z0P9	Gene names	Capn7, Palbh
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN7_HUMAN
θ value	2.0648e-12 (rank : 3)	NC score	0.408685 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN6_MOUSE
θ value	0.0330416 (rank : 4)	NC score	0.182148 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O35646	Gene names	Capn6, Capa6
Domain Architecture
Description	Calpain-6.

CAN6_HUMAN
θ value	0.0961366 (rank : 5)	NC score	0.177931 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6Q1, Q9UEQ1, Q9UJA8	Gene names	CAPN6, CALPM, CANPX
Domain Architecture
Description	Calpain-6 (Calpamodulin) (CalpM) (Calpain-like protease X-linked).

BPAEA_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.026495 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	1369	Shared Neighborhood Hits	9
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAN11_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.145457 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN3_MOUSE
θ value	0.813845 (rank : 8)	NC score	0.131057 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

NFH_MOUSE
θ value	0.813845 (rank : 9)	NC score	0.012042 (rank : 42)
Query Neighborhood Hits	31	Target Neighborhood Hits	2247	Shared Neighborhood Hits	11
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ANK1_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.016574 (rank : 39)
Query Neighborhood Hits	31	Target Neighborhood Hits	430	Shared Neighborhood Hits	6
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

CAN12_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.146115 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CAN1_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.137323 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN1_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.135276 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN12_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.139817 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CAN2_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.137922 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN2_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.137505 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	69	Shared Neighborhood Hits	13
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

MYEF2_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.031562 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2K5, Q6NUM5, Q7L388, Q7Z4B7, Q9H922, Q9NUQ1	Gene names	MYEF2, KIAA1341
Domain Architecture	No domain graphic available
Description	Myelin expression factor 2 (MyEF-2) (MST156).

MICA3_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.017919 (rank : 37)
Query Neighborhood Hits	31	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

PEPL1_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.034551 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NDH3, Q53G37, Q5W083, Q8TF28, Q8WUI2, Q9H1T6, Q9HAI5	Gene names	NPEPL1, KIAA1974
Domain Architecture
Description	Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1).

PHF3_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.029613 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

A20A1_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.024565 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	698	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.024314 (rank : 34)
Query Neighborhood Hits	31	Target Neighborhood Hits	716	Shared Neighborhood Hits	9
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.024364 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	692	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.024278 (rank : 35)
Query Neighborhood Hits	31	Target Neighborhood Hits	710	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

N4BP2_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.032833 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

VP13A_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.031947 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

MYEF2_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.026594 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C854, Q60690, Q6P930, Q6ZPT3, Q8QZZ1	Gene names	Myef2, Kiaa1341, Mef2
Domain Architecture	No domain graphic available
Description	Myelin expression factor 2 (MyEF-2) (MEF-2).

NEBU_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.015282 (rank : 40)
Query Neighborhood Hits	31	Target Neighborhood Hits	420	Shared Neighborhood Hits	3
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

TCAL5_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.012318 (rank : 41)
Query Neighborhood Hits	31	Target Neighborhood Hits	806	Shared Neighborhood Hits	4
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

DBF4_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.019461 (rank : 36)
Query Neighborhood Hits	31	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

MDM2_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.017109 (rank : 38)
Query Neighborhood Hits	31	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

CAN10_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.138292 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HC96, Q8NCD4, Q96IG4, Q96JI2, Q9HC89, Q9HC90, Q9HC91, Q9HC92, Q9HC93, Q9HC94, Q9HC95	Gene names	CAPN10, KIAA1845
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN10_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.134812 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN3_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.119476 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CAN5_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.149692 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	O15484, O00263	Gene names	CAPN5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3) (htra-3).

CAN5_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.151683 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).

CAN9_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.126099 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN9_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.125604 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CPNS1_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.053568 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS1_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.053960 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS2_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.053510 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CPNS2_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.052793 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

Hits sorted by NC score

CF103_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

CAN7_HUMAN
NC score	0.408685 (rank : 2)	θ value	2.0648e-12 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN7_MOUSE
NC score	0.408132 (rank : 3)	θ value	1.58096e-12 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	66	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1S8, Q9Z0P9	Gene names	Capn7, Palbh
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN6_MOUSE
NC score	0.182148 (rank : 4)	θ value	0.0330416 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O35646	Gene names	Capn6, Capa6
Domain Architecture
Description	Calpain-6.

CAN6_HUMAN
NC score	0.177931 (rank : 5)	θ value	0.0961366 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6Q1, Q9UEQ1, Q9UJA8	Gene names	CAPN6, CALPM, CANPX
Domain Architecture
Description	Calpain-6 (Calpamodulin) (CalpM) (Calpain-like protease X-linked).

CAN5_MOUSE
NC score	0.151683 (rank : 6)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).

CAN5_HUMAN
NC score	0.149692 (rank : 7)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	O15484, O00263	Gene names	CAPN5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3) (htra-3).

CAN12_HUMAN
NC score	0.146115 (rank : 8)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CAN11_HUMAN
NC score	0.145457 (rank : 9)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN12_MOUSE
NC score	0.139817 (rank : 10)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CAN10_HUMAN
NC score	0.138292 (rank : 11)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HC96, Q8NCD4, Q96IG4, Q96JI2, Q9HC89, Q9HC90, Q9HC91, Q9HC92, Q9HC93, Q9HC94, Q9HC95	Gene names	CAPN10, KIAA1845
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN2_HUMAN
NC score	0.137922 (rank : 12)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN2_MOUSE
NC score	0.137505 (rank : 13)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	69	Shared Neighborhood Hits	13
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CAN1_HUMAN
NC score	0.137323 (rank : 14)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN1_MOUSE
NC score	0.135276 (rank : 15)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN10_MOUSE
NC score	0.134812 (rank : 16)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN3_MOUSE
NC score	0.131057 (rank : 17)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CAN9_HUMAN
NC score	0.126099 (rank : 18)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	31	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN9_MOUSE
NC score	0.125604 (rank : 19)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	31	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAN3_HUMAN
NC score	0.119476 (rank : 20)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	31	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CPNS1_MOUSE
NC score	0.053960 (rank : 21)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	31	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS1_HUMAN
NC score	0.053568 (rank : 22)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	31	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS2_HUMAN
NC score	0.053510 (rank : 23)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	31	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CPNS2_MOUSE
NC score	0.052793 (rank : 24)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	31	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

PEPL1_HUMAN
NC score	0.034551 (rank : 25)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NDH3, Q53G37, Q5W083, Q8TF28, Q8WUI2, Q9H1T6, Q9HAI5	Gene names	NPEPL1, KIAA1974
Domain Architecture
Description	Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1).

N4BP2_HUMAN
NC score	0.032833 (rank : 26)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

VP13A_HUMAN
NC score	0.031947 (rank : 27)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

MYEF2_HUMAN
NC score	0.031562 (rank : 28)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2K5, Q6NUM5, Q7L388, Q7Z4B7, Q9H922, Q9NUQ1	Gene names	MYEF2, KIAA1341
Domain Architecture	No domain graphic available
Description	Myelin expression factor 2 (MyEF-2) (MST156).

PHF3_HUMAN
NC score	0.029613 (rank : 29)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

MYEF2_MOUSE
NC score	0.026594 (rank : 30)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C854, Q60690, Q6P930, Q6ZPT3, Q8QZZ1	Gene names	Myef2, Kiaa1341, Mef2
Domain Architecture	No domain graphic available
Description	Myelin expression factor 2 (MyEF-2) (MEF-2).

BPAEA_HUMAN
NC score	0.026495 (rank : 31)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	1369	Shared Neighborhood Hits	9
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

A20A1_HUMAN
NC score	0.024565 (rank : 32)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	698	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A3_HUMAN
NC score	0.024364 (rank : 33)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	692	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.024314 (rank : 34)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	716	Shared Neighborhood Hits	9
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A4_HUMAN
NC score	0.024278 (rank : 35)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	710	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

DBF4_HUMAN
NC score	0.019461 (rank : 36)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

MICA3_HUMAN
NC score	0.017919 (rank : 37)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

MDM2_MOUSE
NC score	0.017109 (rank : 38)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

ANK1_MOUSE
NC score	0.016574 (rank : 39)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	430	Shared Neighborhood Hits	6
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

NEBU_HUMAN
NC score	0.015282 (rank : 40)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	420	Shared Neighborhood Hits	3
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

TCAL5_HUMAN
NC score	0.012318 (rank : 41)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	806	Shared Neighborhood Hits	4
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

NFH_MOUSE
NC score	0.012042 (rank : 42)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	2247	Shared Neighborhood Hits	11
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).