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Network neighborhood for query Sequence : CAN3_MOUSE

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CAN3_MOUSE
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAN11_HUMAN
θ value	0 (rank : 1)	NC score	0.986356 (rank : 4)
Query Neighborhood Hits	115	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN1_HUMAN
θ value	0 (rank : 2)	NC score	0.985679 (rank : 6)
Query Neighborhood Hits	115	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN1_MOUSE
θ value	0 (rank : 3)	NC score	0.985990 (rank : 5)
Query Neighborhood Hits	115	Target Neighborhood Hits	83	Shared Neighborhood Hits	49
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN2_HUMAN
θ value	0 (rank : 4)	NC score	0.985207 (rank : 8)
Query Neighborhood Hits	115	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN2_MOUSE
θ value	0 (rank : 5)	NC score	0.985530 (rank : 7)
Query Neighborhood Hits	115	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CAN3_HUMAN
θ value	0 (rank : 6)	NC score	0.996198 (rank : 2)
Query Neighborhood Hits	115	Target Neighborhood Hits	96	Shared Neighborhood Hits	65
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CAN3_MOUSE
θ value	0 (rank : 7)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	115	Target Neighborhood Hits	115	Shared Neighborhood Hits	115
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CAN9_HUMAN
θ value	0 (rank : 8)	NC score	0.987568 (rank : 3)
Query Neighborhood Hits	115	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN9_MOUSE
θ value	0 (rank : 9)	NC score	0.985104 (rank : 9)
Query Neighborhood Hits	115	Target Neighborhood Hits	73	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAN12_HUMAN
θ value	1.42914e-130 (rank : 10)	NC score	0.968246 (rank : 10)
Query Neighborhood Hits	115	Target Neighborhood Hits	47	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CAN12_MOUSE
θ value	1.86652e-130 (rank : 11)	NC score	0.967988 (rank : 11)
Query Neighborhood Hits	115	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CAN5_MOUSE
θ value	1.54114e-100 (rank : 12)	NC score	0.876250 (rank : 12)
Query Neighborhood Hits	115	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).

CAN5_HUMAN
θ value	4.48402e-100 (rank : 13)	NC score	0.875701 (rank : 13)
Query Neighborhood Hits	115	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	O15484, O00263	Gene names	CAPN5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3) (htra-3).

CAN6_HUMAN
θ value	1.03855e-80 (rank : 14)	NC score	0.863824 (rank : 14)
Query Neighborhood Hits	115	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6Q1, Q9UEQ1, Q9UJA8	Gene names	CAPN6, CALPM, CANPX
Domain Architecture
Description	Calpain-6 (Calpamodulin) (CalpM) (Calpain-like protease X-linked).

CAN6_MOUSE
θ value	1.26953e-78 (rank : 15)	NC score	0.862866 (rank : 15)
Query Neighborhood Hits	115	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O35646	Gene names	Capn6, Capa6
Domain Architecture
Description	Calpain-6.

CPNS1_MOUSE
θ value	1.7238e-59 (rank : 16)	NC score	0.834742 (rank : 18)
Query Neighborhood Hits	115	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS1_HUMAN
θ value	2.94036e-59 (rank : 17)	NC score	0.833299 (rank : 19)
Query Neighborhood Hits	115	Target Neighborhood Hits	57	Shared Neighborhood Hits	39
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CAN10_MOUSE
θ value	1.36585e-56 (rank : 18)	NC score	0.848119 (rank : 16)
Query Neighborhood Hits	115	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CPNS2_MOUSE
θ value	2.57589e-55 (rank : 19)	NC score	0.825844 (rank : 21)
Query Neighborhood Hits	115	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CPNS2_HUMAN
θ value	3.36421e-55 (rank : 20)	NC score	0.829905 (rank : 20)
Query Neighborhood Hits	115	Target Neighborhood Hits	66	Shared Neighborhood Hits	45
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CAN10_HUMAN
θ value	7.01481e-53 (rank : 21)	NC score	0.844000 (rank : 17)
Query Neighborhood Hits	115	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC96, Q8NCD4, Q96IG4, Q96JI2, Q9HC89, Q9HC90, Q9HC91, Q9HC92, Q9HC93, Q9HC94, Q9HC95	Gene names	CAPN10, KIAA1845
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

SORCN_HUMAN
θ value	1.86321e-21 (rank : 22)	NC score	0.710882 (rank : 24)
Query Neighborhood Hits	115	Target Neighborhood Hits	82	Shared Neighborhood Hits	42
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

SORCN_MOUSE
θ value	1.86321e-21 (rank : 23)	NC score	0.715455 (rank : 22)
Query Neighborhood Hits	115	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

GRAN_MOUSE
θ value	9.24701e-21 (rank : 24)	NC score	0.714887 (rank : 23)
Query Neighborhood Hits	115	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VC88, Q8BL53, Q8K3Z6	Gene names	Gca
Domain Architecture	No domain graphic available
Description	Grancalcin.

GRAN_HUMAN
θ value	1.02238e-19 (rank : 25)	NC score	0.707966 (rank : 25)
Query Neighborhood Hits	115	Target Neighborhood Hits	57	Shared Neighborhood Hits	35
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

PDCD6_HUMAN
θ value	1.99529e-15 (rank : 26)	NC score	0.598934 (rank : 30)
Query Neighborhood Hits	115	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PDCD6_MOUSE
θ value	2.60593e-15 (rank : 27)	NC score	0.596957 (rank : 31)
Query Neighborhood Hits	115	Target Neighborhood Hits	142	Shared Neighborhood Hits	53
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

CAN7_HUMAN
θ value	9.90251e-15 (rank : 28)	NC score	0.644492 (rank : 29)
Query Neighborhood Hits	115	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN7_MOUSE
θ value	9.90251e-15 (rank : 29)	NC score	0.646703 (rank : 28)
Query Neighborhood Hits	115	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1S8, Q9Z0P9	Gene names	Capn7, Palbh
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

PEF1_HUMAN
θ value	1.29331e-14 (rank : 30)	NC score	0.654447 (rank : 27)
Query Neighborhood Hits	115	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PEF1_MOUSE
θ value	2.20605e-14 (rank : 31)	NC score	0.667490 (rank : 26)
Query Neighborhood Hits	115	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

CALL5_HUMAN
θ value	1.43324e-05 (rank : 32)	NC score	0.207510 (rank : 32)
Query Neighborhood Hits	115	Target Neighborhood Hits	231	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CALM_HUMAN
θ value	0.000461057 (rank : 33)	NC score	0.135367 (rank : 34)
Query Neighborhood Hits	115	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	0.000461057 (rank : 34)	NC score	0.135367 (rank : 35)
Query Neighborhood Hits	115	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CALM4_MOUSE
θ value	0.00134147 (rank : 35)	NC score	0.167854 (rank : 33)
Query Neighborhood Hits	115	Target Neighborhood Hits	229	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CALB1_HUMAN
θ value	0.00509761 (rank : 36)	NC score	0.110947 (rank : 47)
Query Neighborhood Hits	115	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CALB1_MOUSE
θ value	0.00509761 (rank : 37)	NC score	0.115586 (rank : 42)
Query Neighborhood Hits	115	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

HM20B_MOUSE
θ value	0.00509761 (rank : 38)	NC score	0.034143 (rank : 77)
Query Neighborhood Hits	115	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

CALL3_HUMAN
θ value	0.0563607 (rank : 39)	NC score	0.128356 (rank : 38)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

SEGN_HUMAN
θ value	0.0961366 (rank : 40)	NC score	0.104287 (rank : 50)
Query Neighborhood Hits	115	Target Neighborhood Hits	96	Shared Neighborhood Hits	33
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

SEGN_MOUSE
θ value	0.0961366 (rank : 41)	NC score	0.092247 (rank : 52)
Query Neighborhood Hits	115	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

MYST3_HUMAN
θ value	0.125558 (rank : 42)	NC score	0.012318 (rank : 99)
Query Neighborhood Hits	115	Target Neighborhood Hits	772	Shared Neighborhood Hits	15
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

VISL1_HUMAN
θ value	0.125558 (rank : 43)	NC score	0.029272 (rank : 80)
Query Neighborhood Hits	115	Target Neighborhood Hits	124	Shared Neighborhood Hits	27
SwissProt Accessions	P62760, P28677, P29103, P42323, Q9UM20	Gene names	VSNL1, VISL1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Hippocalcin-like protein 3) (HLP3).

VISL1_MOUSE
θ value	0.125558 (rank : 44)	NC score	0.029272 (rank : 81)
Query Neighborhood Hits	115	Target Neighborhood Hits	124	Shared Neighborhood Hits	27
SwissProt Accessions	P62761, P28677, P29103, P42323, Q9UM20	Gene names	Vsnl1, Visl1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Neural visinin-like protein 1) (NVL-1) (NVP-1).

HMGB1_HUMAN
θ value	0.163984 (rank : 45)	NC score	0.021661 (rank : 89)
Query Neighborhood Hits	115	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	0.163984 (rank : 46)	NC score	0.021698 (rank : 88)
Query Neighborhood Hits	115	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

CALL6_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.079947 (rank : 66)
Query Neighborhood Hits	115	Target Neighborhood Hits	157	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

EFHB_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.051510 (rank : 76)
Query Neighborhood Hits	115	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

SPTA2_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.029132 (rank : 82)
Query Neighborhood Hits	115	Target Neighborhood Hits	888	Shared Neighborhood Hits	42
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

TNNC2_MOUSE
θ value	0.279714 (rank : 50)	NC score	0.112801 (rank : 46)
Query Neighborhood Hits	115	Target Neighborhood Hits	233	Shared Neighborhood Hits	51
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

CABP1_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.091999 (rank : 53)
Query Neighborhood Hits	115	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CABP1_MOUSE
θ value	0.365318 (rank : 52)	NC score	0.092583 (rank : 51)
Query Neighborhood Hits	115	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CANB2_MOUSE
θ value	0.365318 (rank : 53)	NC score	0.077235 (rank : 67)
Query Neighborhood Hits	115	Target Neighborhood Hits	173	Shared Neighborhood Hits	41
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CTNL1_HUMAN
θ value	0.47712 (rank : 54)	NC score	0.023623 (rank : 86)
Query Neighborhood Hits	115	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBT7, O76084, Q53FQ2, Q5JTQ7, Q5JTQ8, Q9Y401	Gene names	CTNNAL1
Domain Architecture	No domain graphic available
Description	Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) (ACRP).

HM20B_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.025885 (rank : 85)
Query Neighborhood Hits	115	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HNRPU_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.017972 (rank : 93)
Query Neighborhood Hits	115	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

TNNC2_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.109015 (rank : 49)
Query Neighborhood Hits	115	Target Neighborhood Hits	234	Shared Neighborhood Hits	51
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

CF103_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.131057 (rank : 37)
Query Neighborhood Hits	115	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

ASPH_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.022776 (rank : 87)
Query Neighborhood Hits	115	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

EFHB_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.060426 (rank : 72)
Query Neighborhood Hits	115	Target Neighborhood Hits	125	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N7U6, Q6ZWK9, Q8IV58, Q96LQ6	Gene names	EFHB
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

CCAR1_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.014517 (rank : 95)
Query Neighborhood Hits	115	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CENPE_HUMAN
θ value	1.38821 (rank : 62)	NC score	-0.001020 (rank : 132)
Query Neighborhood Hits	115	Target Neighborhood Hits	2060	Shared Neighborhood Hits	25
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DSG3_MOUSE
θ value	1.38821 (rank : 63)	NC score	0.003557 (rank : 120)
Query Neighborhood Hits	115	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	O35902, Q8CB02, Q8CE48	Gene names	Dsg3
Domain Architecture	No domain graphic available
Description	Desmoglein-3 precursor (130 kDa pemphigus vulgaris antigen homolog).

PLSI_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.088969 (rank : 56)
Query Neighborhood Hits	115	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

BMP2K_MOUSE
θ value	1.81305 (rank : 65)	NC score	-0.001620 (rank : 133)
Query Neighborhood Hits	115	Target Neighborhood Hits	874	Shared Neighborhood Hits	5
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CETN1_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.133621 (rank : 36)
Query Neighborhood Hits	115	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

MAP1B_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.007159 (rank : 108)
Query Neighborhood Hits	115	Target Neighborhood Hits	903	Shared Neighborhood Hits	15
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NFL_HUMAN
θ value	1.81305 (rank : 68)	NC score	0.000805 (rank : 130)
Query Neighborhood Hits	115	Target Neighborhood Hits	666	Shared Neighborhood Hits	12
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

SFPQ_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.007358 (rank : 107)
Query Neighborhood Hits	115	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

ACTN1_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.027918 (rank : 84)
Query Neighborhood Hits	115	Target Neighborhood Hits	221	Shared Neighborhood Hits	34
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.028840 (rank : 83)
Query Neighborhood Hits	115	Target Neighborhood Hits	216	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

CABP5_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.082886 (rank : 65)
Query Neighborhood Hits	115	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CCAR1_MOUSE
θ value	2.36792 (rank : 73)	NC score	0.014462 (rank : 96)
Query Neighborhood Hits	115	Target Neighborhood Hits	414	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CETN1_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.121993 (rank : 40)
Query Neighborhood Hits	115	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

FOXD1_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.001976 (rank : 126)
Query Neighborhood Hits	115	Target Neighborhood Hits	122	Shared Neighborhood Hits	2
SwissProt Accessions	Q16676, Q12949	Gene names	FOXD1, FKHL8, FREAC4
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4).

IF5_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.012929 (rank : 97)
Query Neighborhood Hits	115	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

MYO6_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.003143 (rank : 121)
Query Neighborhood Hits	115	Target Neighborhood Hits	586	Shared Neighborhood Hits	9
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

PPE1_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.032762 (rank : 79)
Query Neighborhood Hits	115	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

SFPQ_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.004914 (rank : 113)
Query Neighborhood Hits	115	Target Neighborhood Hits	986	Shared Neighborhood Hits	8
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

BSN_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.004414 (rank : 117)
Query Neighborhood Hits	115	Target Neighborhood Hits	2057	Shared Neighborhood Hits	18
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

E41L1_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.004853 (rank : 115)
Query Neighborhood Hits	115	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

EFCB1_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.034077 (rank : 78)
Query Neighborhood Hits	115	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAE3	Gene names	EFCAB1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

RYR2_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.021460 (rank : 90)
Query Neighborhood Hits	115	Target Neighborhood Hits	175	Shared Neighborhood Hits	22
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

ACTN4_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.020207 (rank : 92)
Query Neighborhood Hits	115	Target Neighborhood Hits	276	Shared Neighborhood Hits	32
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

E41L1_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.004466 (rank : 116)
Query Neighborhood Hits	115	Target Neighborhood Hits	180	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

MYO6_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.002151 (rank : 125)
Query Neighborhood Hits	115	Target Neighborhood Hits	727	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

RPA1_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.010990 (rank : 101)
Query Neighborhood Hits	115	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

RPA1_MOUSE
θ value	4.03905 (rank : 88)	NC score	0.010992 (rank : 100)
Query Neighborhood Hits	115	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

TNNC1_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.127272 (rank : 39)
Query Neighborhood Hits	115	Target Neighborhood Hits	221	Shared Neighborhood Hits	50
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TSH1_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.008483 (rank : 104)
Query Neighborhood Hits	115	Target Neighborhood Hits	675	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

LEO1_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.008293 (rank : 105)
Query Neighborhood Hits	115	Target Neighborhood Hits	958	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MYST3_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.008840 (rank : 102)
Query Neighborhood Hits	115	Target Neighborhood Hits	688	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

TNNC1_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.121103 (rank : 41)
Query Neighborhood Hits	115	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

WNK2_HUMAN
θ value	5.27518 (rank : 94)	NC score	-0.004382 (rank : 135)
Query Neighborhood Hits	115	Target Neighborhood Hits	1407	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AF9_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.005802 (rank : 111)
Query Neighborhood Hits	115	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

ATRX_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.002533 (rank : 123)
Query Neighborhood Hits	115	Target Neighborhood Hits	842	Shared Neighborhood Hits	19
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CD2L1_MOUSE
θ value	6.88961 (rank : 97)	NC score	-0.004844 (rank : 136)
Query Neighborhood Hits	115	Target Neighborhood Hits	1463	Shared Neighborhood Hits	13
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

DSG3_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.001661 (rank : 127)
Query Neighborhood Hits	115	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	P32926	Gene names	DSG3
Domain Architecture
Description	Desmoglein-3 precursor (130 kDa pemphigus vulgaris antigen) (PVA).

ELF2_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.007115 (rank : 109)
Query Neighborhood Hits	115	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHC9, Q6NST2, Q8BTX8, Q9JHC7, Q9JHC8, Q9JHD0	Gene names	Elf2, Nerf
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

MTMRD_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.002918 (rank : 122)
Query Neighborhood Hits	115	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

NASP_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.007832 (rank : 106)
Query Neighborhood Hits	115	Target Neighborhood Hits	709	Shared Neighborhood Hits	25
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NMDE3_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.001624 (rank : 128)
Query Neighborhood Hits	115	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

PCLO_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.000259 (rank : 131)
Query Neighborhood Hits	115	Target Neighborhood Hits	2046	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRGC2_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.005129 (rank : 112)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PTMA_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.016419 (rank : 94)
Query Neighborhood Hits	115	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

STAR8_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.002439 (rank : 124)
Query Neighborhood Hits	115	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

TECT1_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.006186 (rank : 110)
Query Neighborhood Hits	115	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZ64, Q3UMP0, Q8BUE2	Gene names	Tect1
Domain Architecture	No domain graphic available
Description	Tectonic-1 precursor.

ACTN4_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.020437 (rank : 91)
Query Neighborhood Hits	115	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

CHD1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.001016 (rank : 129)
Query Neighborhood Hits	115	Target Neighborhood Hits	337	Shared Neighborhood Hits	6
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CN037_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.004903 (rank : 114)
Query Neighborhood Hits	115	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

HTSF1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.003855 (rank : 118)
Query Neighborhood Hits	115	Target Neighborhood Hits	408	Shared Neighborhood Hits	10
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

IF3I_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.008512 (rank : 103)
Query Neighborhood Hits	115	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y262	Gene names	EIF3S6IP
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 6-interacting protein.

KI21A_HUMAN
θ value	8.99809 (rank : 113)	NC score	-0.001902 (rank : 134)
Query Neighborhood Hits	115	Target Neighborhood Hits	1543	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

PTMA_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.012757 (rank : 98)
Query Neighborhood Hits	115	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

ZN318_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.003593 (rank : 119)
Query Neighborhood Hits	115	Target Neighborhood Hits	497	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

CABP2_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.083476 (rank : 64)
Query Neighborhood Hits	115	Target Neighborhood Hits	205	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP2_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.086588 (rank : 61)
Query Neighborhood Hits	115	Target Neighborhood Hits	204	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP3_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.063560 (rank : 71)
Query Neighborhood Hits	115	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP4_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.114688 (rank : 44)
Query Neighborhood Hits	115	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CABP4_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.085020 (rank : 63)
Query Neighborhood Hits	115	Target Neighborhood Hits	212	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CABP5_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.067223 (rank : 70)
Query Neighborhood Hits	115	Target Neighborhood Hits	207	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP7_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.088503 (rank : 57)
Query Neighborhood Hits	115	Target Neighborhood Hits	205	Shared Neighborhood Hits	44
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.088503 (rank : 58)
Query Neighborhood Hits	115	Target Neighborhood Hits	205	Shared Neighborhood Hits	44
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CALB2_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.112944 (rank : 45)
Query Neighborhood Hits	115	Target Neighborhood Hits	149	Shared Neighborhood Hits	39
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB2_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.085787 (rank : 62)
Query Neighborhood Hits	115	Target Neighborhood Hits	141	Shared Neighborhood Hits	34
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CALN1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.056359 (rank : 73)
Query Neighborhood Hits	115	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.056230 (rank : 74)
Query Neighborhood Hits	115	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CANB1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.087195 (rank : 59)
Query Neighborhood Hits	115	Target Neighborhood Hits	183	Shared Neighborhood Hits	43
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.087192 (rank : 60)
Query Neighborhood Hits	115	Target Neighborhood Hits	183	Shared Neighborhood Hits	43
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.074155 (rank : 68)
Query Neighborhood Hits	115	Target Neighborhood Hits	163	Shared Neighborhood Hits	38
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

CAYP1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.072402 (rank : 69)
Query Neighborhood Hits	115	Target Neighborhood Hits	94	Shared Neighborhood Hits	30
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

CETN2_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.110284 (rank : 48)
Query Neighborhood Hits	115	Target Neighborhood Hits	213	Shared Neighborhood Hits	47
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN2_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.114938 (rank : 43)
Query Neighborhood Hits	115	Target Neighborhood Hits	211	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN3_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.091443 (rank : 55)
Query Neighborhood Hits	115	Target Neighborhood Hits	211	Shared Neighborhood Hits	47
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.091683 (rank : 54)
Query Neighborhood Hits	115	Target Neighborhood Hits	208	Shared Neighborhood Hits	47
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

PRVA_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.055180 (rank : 75)
Query Neighborhood Hits	115	Target Neighborhood Hits	77	Shared Neighborhood Hits	22
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

Hits sorted by NC score

CAN3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 7)
Query Neighborhood Hits	115	Target Neighborhood Hits	115	Shared Neighborhood Hits	115
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CAN3_HUMAN
NC score	0.996198 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	115	Target Neighborhood Hits	96	Shared Neighborhood Hits	65
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CAN9_HUMAN
NC score	0.987568 (rank : 3)	θ value	0 (rank : 8)
Query Neighborhood Hits	115	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN11_HUMAN
NC score	0.986356 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	115	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN1_MOUSE
NC score	0.985990 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	115	Target Neighborhood Hits	83	Shared Neighborhood Hits	49
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN1_HUMAN
NC score	0.985679 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	115	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN2_MOUSE
NC score	0.985530 (rank : 7)	θ value	0 (rank : 5)
Query Neighborhood Hits	115	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CAN2_HUMAN
NC score	0.985207 (rank : 8)	θ value	0 (rank : 4)
Query Neighborhood Hits	115	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN9_MOUSE
NC score	0.985104 (rank : 9)	θ value	0 (rank : 9)
Query Neighborhood Hits	115	Target Neighborhood Hits	73	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAN12_HUMAN
NC score	0.968246 (rank : 10)	θ value	1.42914e-130 (rank : 10)
Query Neighborhood Hits	115	Target Neighborhood Hits	47	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CAN12_MOUSE
NC score	0.967988 (rank : 11)	θ value	1.86652e-130 (rank : 11)
Query Neighborhood Hits	115	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CAN5_MOUSE
NC score	0.876250 (rank : 12)	θ value	1.54114e-100 (rank : 12)
Query Neighborhood Hits	115	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).

CAN5_HUMAN
NC score	0.875701 (rank : 13)	θ value	4.48402e-100 (rank : 13)
Query Neighborhood Hits	115	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	O15484, O00263	Gene names	CAPN5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3) (htra-3).

CAN6_HUMAN
NC score	0.863824 (rank : 14)	θ value	1.03855e-80 (rank : 14)
Query Neighborhood Hits	115	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6Q1, Q9UEQ1, Q9UJA8	Gene names	CAPN6, CALPM, CANPX
Domain Architecture
Description	Calpain-6 (Calpamodulin) (CalpM) (Calpain-like protease X-linked).

CAN6_MOUSE
NC score	0.862866 (rank : 15)	θ value	1.26953e-78 (rank : 15)
Query Neighborhood Hits	115	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O35646	Gene names	Capn6, Capa6
Domain Architecture
Description	Calpain-6.

CAN10_MOUSE
NC score	0.848119 (rank : 16)	θ value	1.36585e-56 (rank : 18)
Query Neighborhood Hits	115	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN10_HUMAN
NC score	0.844000 (rank : 17)	θ value	7.01481e-53 (rank : 21)
Query Neighborhood Hits	115	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC96, Q8NCD4, Q96IG4, Q96JI2, Q9HC89, Q9HC90, Q9HC91, Q9HC92, Q9HC93, Q9HC94, Q9HC95	Gene names	CAPN10, KIAA1845
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CPNS1_MOUSE
NC score	0.834742 (rank : 18)	θ value	1.7238e-59 (rank : 16)
Query Neighborhood Hits	115	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS1_HUMAN
NC score	0.833299 (rank : 19)	θ value	2.94036e-59 (rank : 17)
Query Neighborhood Hits	115	Target Neighborhood Hits	57	Shared Neighborhood Hits	39
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS2_HUMAN
NC score	0.829905 (rank : 20)	θ value	3.36421e-55 (rank : 20)
Query Neighborhood Hits	115	Target Neighborhood Hits	66	Shared Neighborhood Hits	45
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CPNS2_MOUSE
NC score	0.825844 (rank : 21)	θ value	2.57589e-55 (rank : 19)
Query Neighborhood Hits	115	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

SORCN_MOUSE
NC score	0.715455 (rank : 22)	θ value	1.86321e-21 (rank : 23)
Query Neighborhood Hits	115	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

GRAN_MOUSE
NC score	0.714887 (rank : 23)	θ value	9.24701e-21 (rank : 24)
Query Neighborhood Hits	115	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VC88, Q8BL53, Q8K3Z6	Gene names	Gca
Domain Architecture	No domain graphic available
Description	Grancalcin.

SORCN_HUMAN
NC score	0.710882 (rank : 24)	θ value	1.86321e-21 (rank : 22)
Query Neighborhood Hits	115	Target Neighborhood Hits	82	Shared Neighborhood Hits	42
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

GRAN_HUMAN
NC score	0.707966 (rank : 25)	θ value	1.02238e-19 (rank : 25)
Query Neighborhood Hits	115	Target Neighborhood Hits	57	Shared Neighborhood Hits	35
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

PEF1_MOUSE
NC score	0.667490 (rank : 26)	θ value	2.20605e-14 (rank : 31)
Query Neighborhood Hits	115	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PEF1_HUMAN
NC score	0.654447 (rank : 27)	θ value	1.29331e-14 (rank : 30)
Query Neighborhood Hits	115	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

CAN7_MOUSE
NC score	0.646703 (rank : 28)	θ value	9.90251e-15 (rank : 29)
Query Neighborhood Hits	115	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1S8, Q9Z0P9	Gene names	Capn7, Palbh
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN7_HUMAN
NC score	0.644492 (rank : 29)	θ value	9.90251e-15 (rank : 28)
Query Neighborhood Hits	115	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

PDCD6_HUMAN
NC score	0.598934 (rank : 30)	θ value	1.99529e-15 (rank : 26)
Query Neighborhood Hits	115	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PDCD6_MOUSE
NC score	0.596957 (rank : 31)	θ value	2.60593e-15 (rank : 27)
Query Neighborhood Hits	115	Target Neighborhood Hits	142	Shared Neighborhood Hits	53
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

CALL5_HUMAN
NC score	0.207510 (rank : 32)	θ value	1.43324e-05 (rank : 32)
Query Neighborhood Hits	115	Target Neighborhood Hits	231	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CALM4_MOUSE
NC score	0.167854 (rank : 33)	θ value	0.00134147 (rank : 35)
Query Neighborhood Hits	115	Target Neighborhood Hits	229	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CALM_HUMAN
NC score	0.135367 (rank : 34)	θ value	0.000461057 (rank : 33)
Query Neighborhood Hits	115	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.135367 (rank : 35)	θ value	0.000461057 (rank : 34)
Query Neighborhood Hits	115	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CETN1_HUMAN
NC score	0.133621 (rank : 36)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	115	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CF103_HUMAN
NC score	0.131057 (rank : 37)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	115	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

CALL3_HUMAN
NC score	0.128356 (rank : 38)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

TNNC1_MOUSE
NC score	0.127272 (rank : 39)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	115	Target Neighborhood Hits	221	Shared Neighborhood Hits	50
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CETN1_MOUSE
NC score	0.121993 (rank : 40)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	115	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

TNNC1_HUMAN
NC score	0.121103 (rank : 41)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	115	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CALB1_MOUSE
NC score	0.115586 (rank : 42)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	115	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

CETN2_MOUSE
NC score	0.114938 (rank : 43)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	115	Target Neighborhood Hits	211	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CABP4_HUMAN
NC score	0.114688 (rank : 44)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	115	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CALB2_HUMAN
NC score	0.112944 (rank : 45)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	115	Target Neighborhood Hits	149	Shared Neighborhood Hits	39
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

TNNC2_MOUSE
NC score	0.112801 (rank : 46)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	115	Target Neighborhood Hits	233	Shared Neighborhood Hits	51
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

CALB1_HUMAN
NC score	0.110947 (rank : 47)	θ value	0.00509761 (rank : 36)
Query Neighborhood Hits	115	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CETN2_HUMAN
NC score	0.110284 (rank : 48)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	115	Target Neighborhood Hits	213	Shared Neighborhood Hits	47
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

TNNC2_HUMAN
NC score	0.109015 (rank : 49)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	115	Target Neighborhood Hits	234	Shared Neighborhood Hits	51
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

SEGN_HUMAN
NC score	0.104287 (rank : 50)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	115	Target Neighborhood Hits	96	Shared Neighborhood Hits	33
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

CABP1_MOUSE
NC score	0.092583 (rank : 51)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	115	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

SEGN_MOUSE
NC score	0.092247 (rank : 52)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	115	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

CABP1_HUMAN
NC score	0.091999 (rank : 53)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	115	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CETN3_MOUSE
NC score	0.091683 (rank : 54)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	115	Target Neighborhood Hits	208	Shared Neighborhood Hits	47
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

CETN3_HUMAN
NC score	0.091443 (rank : 55)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	115	Target Neighborhood Hits	211	Shared Neighborhood Hits	47
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

PLSI_HUMAN
NC score	0.088969 (rank : 56)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	115	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

CABP7_HUMAN
NC score	0.088503 (rank : 57)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	115	Target Neighborhood Hits	205	Shared Neighborhood Hits	44
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
NC score	0.088503 (rank : 58)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	115	Target Neighborhood Hits	205	Shared Neighborhood Hits	44
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CANB1_HUMAN
NC score	0.087195 (rank : 59)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	115	Target Neighborhood Hits	183	Shared Neighborhood Hits	43
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
NC score	0.087192 (rank : 60)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	115	Target Neighborhood Hits	183	Shared Neighborhood Hits	43
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CABP2_MOUSE
NC score	0.086588 (rank : 61)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	115	Target Neighborhood Hits	204	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CALB2_MOUSE
NC score	0.085787 (rank : 62)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	115	Target Neighborhood Hits	141	Shared Neighborhood Hits	34
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CABP4_MOUSE
NC score	0.085020 (rank : 63)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	115	Target Neighborhood Hits	212	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CABP2_HUMAN
NC score	0.083476 (rank : 64)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	115	Target Neighborhood Hits	205	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP5_HUMAN
NC score	0.082886 (rank : 65)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	115	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CALL6_HUMAN
NC score	0.079947 (rank : 66)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	115	Target Neighborhood Hits	157	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

CANB2_MOUSE
NC score	0.077235 (rank : 67)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	115	Target Neighborhood Hits	173	Shared Neighborhood Hits	41
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CANB2_HUMAN
NC score	0.074155 (rank : 68)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	115	Target Neighborhood Hits	163	Shared Neighborhood Hits	38
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

CAYP1_HUMAN
NC score	0.072402 (rank : 69)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	115	Target Neighborhood Hits	94	Shared Neighborhood Hits	30
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

CABP5_MOUSE
NC score	0.067223 (rank : 70)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	115	Target Neighborhood Hits	207	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP3_HUMAN
NC score	0.063560 (rank : 71)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	115	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

EFHB_HUMAN
NC score	0.060426 (rank : 72)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	115	Target Neighborhood Hits	125	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N7U6, Q6ZWK9, Q8IV58, Q96LQ6	Gene names	EFHB
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

CALN1_HUMAN
NC score	0.056359 (rank : 73)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	115	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
NC score	0.056230 (rank : 74)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	115	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

PRVA_MOUSE
NC score	0.055180 (rank : 75)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	115	Target Neighborhood Hits	77	Shared Neighborhood Hits	22
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

EFHB_MOUSE
NC score	0.051510 (rank : 76)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	115	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

HM20B_MOUSE
NC score	0.034143 (rank : 77)	θ value	0.00509761 (rank : 38)
Query Neighborhood Hits	115	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

EFCB1_HUMAN
NC score	0.034077 (rank : 78)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	115	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAE3	Gene names	EFCAB1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

PPE1_HUMAN
NC score	0.032762 (rank : 79)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	115	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

VISL1_HUMAN
NC score	0.029272 (rank : 80)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	115	Target Neighborhood Hits	124	Shared Neighborhood Hits	27
SwissProt Accessions	P62760, P28677, P29103, P42323, Q9UM20	Gene names	VSNL1, VISL1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Hippocalcin-like protein 3) (HLP3).

VISL1_MOUSE
NC score	0.029272 (rank : 81)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	115	Target Neighborhood Hits	124	Shared Neighborhood Hits	27
SwissProt Accessions	P62761, P28677, P29103, P42323, Q9UM20	Gene names	Vsnl1, Visl1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Neural visinin-like protein 1) (NVL-1) (NVP-1).

SPTA2_HUMAN
NC score	0.029132 (rank : 82)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	115	Target Neighborhood Hits	888	Shared Neighborhood Hits	42
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ACTN1_MOUSE
NC score	0.028840 (rank : 83)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	115	Target Neighborhood Hits	216	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_HUMAN
NC score	0.027918 (rank : 84)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	115	Target Neighborhood Hits	221	Shared Neighborhood Hits	34
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

HM20B_HUMAN
NC score	0.025885 (rank : 85)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	115	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

CTNL1_HUMAN
NC score	0.023623 (rank : 86)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	115	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBT7, O76084, Q53FQ2, Q5JTQ7, Q5JTQ8, Q9Y401	Gene names	CTNNAL1
Domain Architecture	No domain graphic available
Description	Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) (ACRP).

ASPH_HUMAN
NC score	0.022776 (rank : 87)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	115	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

HMGB1_MOUSE
NC score	0.021698 (rank : 88)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	115	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_HUMAN
NC score	0.021661 (rank : 89)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	115	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

RYR2_HUMAN
NC score	0.021460 (rank : 90)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	115	Target Neighborhood Hits	175	Shared Neighborhood Hits	22
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

ACTN4_HUMAN
NC score	0.020437 (rank : 91)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	115	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
NC score	0.020207 (rank : 92)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	115	Target Neighborhood Hits	276	Shared Neighborhood Hits	32
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

HNRPU_HUMAN
NC score	0.017972 (rank : 93)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	115	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

PTMA_MOUSE
NC score	0.016419 (rank : 94)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	115	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

CCAR1_HUMAN
NC score	0.014517 (rank : 95)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	115	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CCAR1_MOUSE
NC score	0.014462 (rank : 96)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	115	Target Neighborhood Hits	414	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

IF5_MOUSE
NC score	0.012929 (rank : 97)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	115	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

PTMA_HUMAN
NC score	0.012757 (rank : 98)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	115	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

MYST3_HUMAN
NC score	0.012318 (rank : 99)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	115	Target Neighborhood Hits	772	Shared Neighborhood Hits	15
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

RPA1_MOUSE
NC score	0.010992 (rank : 100)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	115	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

RPA1_HUMAN
NC score	0.010990 (rank : 101)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	115	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

MYST3_MOUSE
NC score	0.008840 (rank : 102)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	115	Target Neighborhood Hits	688	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

IF3I_HUMAN
NC score	0.008512 (rank : 103)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	115	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y262	Gene names	EIF3S6IP
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 6-interacting protein.

TSH1_MOUSE
NC score	0.008483 (rank : 104)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	115	Target Neighborhood Hits	675	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

LEO1_HUMAN
NC score	0.008293 (rank : 105)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	115	Target Neighborhood Hits	958	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NASP_HUMAN
NC score	0.007832 (rank : 106)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	115	Target Neighborhood Hits	709	Shared Neighborhood Hits	25
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SFPQ_MOUSE
NC score	0.007358 (rank : 107)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	115	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

MAP1B_HUMAN
NC score	0.007159 (rank : 108)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	115	Target Neighborhood Hits	903	Shared Neighborhood Hits	15
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

ELF2_MOUSE
NC score	0.007115 (rank : 109)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	115	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHC9, Q6NST2, Q8BTX8, Q9JHC7, Q9JHC8, Q9JHD0	Gene names	Elf2, Nerf
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

TECT1_MOUSE
NC score	0.006186 (rank : 110)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	115	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZ64, Q3UMP0, Q8BUE2	Gene names	Tect1
Domain Architecture	No domain graphic available
Description	Tectonic-1 precursor.

AF9_HUMAN
NC score	0.005802 (rank : 111)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	115	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

PRGC2_MOUSE
NC score	0.005129 (rank : 112)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

SFPQ_HUMAN
NC score	0.004914 (rank : 113)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	115	Target Neighborhood Hits	986	Shared Neighborhood Hits	8
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

CN037_MOUSE
NC score	0.004903 (rank : 114)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	115	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

E41L1_MOUSE
NC score	0.004853 (rank : 115)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	115	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
NC score	0.004466 (rank : 116)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	115	Target Neighborhood Hits	180	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

BSN_MOUSE
NC score	0.004414 (rank : 117)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	115	Target Neighborhood Hits	2057	Shared Neighborhood Hits	18
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

HTSF1_HUMAN
NC score	0.003855 (rank : 118)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	115	Target Neighborhood Hits	408	Shared Neighborhood Hits	10
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

ZN318_HUMAN
NC score	0.003593 (rank : 119)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	115	Target Neighborhood Hits	497	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

DSG3_MOUSE
NC score	0.003557 (rank : 120)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	115	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	O35902, Q8CB02, Q8CE48	Gene names	Dsg3
Domain Architecture	No domain graphic available
Description	Desmoglein-3 precursor (130 kDa pemphigus vulgaris antigen homolog).

MYO6_MOUSE
NC score	0.003143 (rank : 121)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	115	Target Neighborhood Hits	586	Shared Neighborhood Hits	9
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

MTMRD_HUMAN
NC score	0.002918 (rank : 122)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	115	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

ATRX_HUMAN
NC score	0.002533 (rank : 123)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	115	Target Neighborhood Hits	842	Shared Neighborhood Hits	19
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

STAR8_HUMAN
NC score	0.002439 (rank : 124)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	115	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

MYO6_HUMAN
NC score	0.002151 (rank : 125)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	115	Target Neighborhood Hits	727	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

FOXD1_HUMAN
NC score	0.001976 (rank : 126)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	115	Target Neighborhood Hits	122	Shared Neighborhood Hits	2
SwissProt Accessions	Q16676, Q12949	Gene names	FOXD1, FKHL8, FREAC4
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4).

DSG3_HUMAN
NC score	0.001661 (rank : 127)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	115	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	P32926	Gene names	DSG3
Domain Architecture
Description	Desmoglein-3 precursor (130 kDa pemphigus vulgaris antigen) (PVA).

NMDE3_HUMAN
NC score	0.001624 (rank : 128)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	115	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

CHD1_HUMAN
NC score	0.001016 (rank : 129)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	115	Target Neighborhood Hits	337	Shared Neighborhood Hits	6
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NFL_HUMAN
NC score	0.000805 (rank : 130)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	115	Target Neighborhood Hits	666	Shared Neighborhood Hits	12
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

PCLO_HUMAN
NC score	0.000259 (rank : 131)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	115	Target Neighborhood Hits	2046	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CENPE_HUMAN
NC score	-0.001020 (rank : 132)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	115	Target Neighborhood Hits	2060	Shared Neighborhood Hits	25
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

BMP2K_MOUSE
NC score	-0.001620 (rank : 133)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	115	Target Neighborhood Hits	874	Shared Neighborhood Hits	5
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

KI21A_HUMAN
NC score	-0.001902 (rank : 134)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	115	Target Neighborhood Hits	1543	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

WNK2_HUMAN
NC score	-0.004382 (rank : 135)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	115	Target Neighborhood Hits	1407	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CD2L1_MOUSE
NC score	-0.004844 (rank : 136)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	115	Target Neighborhood Hits	1463	Shared Neighborhood Hits	13
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).