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Network neighborhood for query Sequence : CAN5_MOUSE

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CAN5_MOUSE
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAN5_HUMAN
θ value	0 (rank : 1)	NC score	0.999696 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	22
SwissProt Accessions	O15484, O00263	Gene names	CAPN5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3) (htra-3).

CAN5_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).

CAN6_HUMAN
θ value	1.50931e-172 (rank : 3)	NC score	0.987784 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6Q1, Q9UEQ1, Q9UJA8	Gene names	CAPN6, CALPM, CANPX
Domain Architecture
Description	Calpain-6 (Calpamodulin) (CalpM) (Calpain-like protease X-linked).

CAN6_MOUSE
θ value	5.36813e-170 (rank : 4)	NC score	0.987233 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O35646	Gene names	Capn6, Capa6
Domain Architecture
Description	Calpain-6.

CAN3_HUMAN
θ value	1.18001e-100 (rank : 5)	NC score	0.880215 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CAN3_MOUSE
θ value	1.54114e-100 (rank : 6)	NC score	0.876250 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CAN9_HUMAN
θ value	3.4333e-100 (rank : 7)	NC score	0.897784 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN1_MOUSE
θ value	1.70393e-99 (rank : 8)	NC score	0.886146 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	83	Shared Neighborhood Hits	19
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN2_HUMAN
θ value	1.88391e-98 (rank : 9)	NC score	0.895587 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN9_MOUSE
θ value	2.46047e-98 (rank : 10)	NC score	0.897258 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	73	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAN2_MOUSE
θ value	4.64023e-97 (rank : 11)	NC score	0.892959 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CAN1_HUMAN
θ value	1.49272e-95 (rank : 12)	NC score	0.885407 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN11_HUMAN
θ value	1.94955e-95 (rank : 13)	NC score	0.897563 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN12_MOUSE
θ value	9.7205e-79 (rank : 14)	NC score	0.916393 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CAN12_HUMAN
θ value	1.5519e-76 (rank : 15)	NC score	0.918126 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CAN10_MOUSE
θ value	1.19377e-60 (rank : 16)	NC score	0.936683 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN10_HUMAN
θ value	4.69435e-57 (rank : 17)	NC score	0.933243 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC96, Q8NCD4, Q96IG4, Q96JI2, Q9HC89, Q9HC90, Q9HC91, Q9HC92, Q9HC93, Q9HC94, Q9HC95	Gene names	CAPN10, KIAA1845
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN7_MOUSE
θ value	2.05525e-28 (rank : 18)	NC score	0.765149 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	66	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1S8, Q9Z0P9	Gene names	Capn7, Palbh
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN7_HUMAN
θ value	3.50572e-28 (rank : 19)	NC score	0.763843 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

FA62A_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.034800 (rank : 36)
Query Neighborhood Hits	25	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

UN13A_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.027797 (rank : 37)
Query Neighborhood Hits	25	Target Neighborhood Hits	285	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

K0406_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.014002 (rank : 38)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O43156, Q5JX67, Q96A38, Q9BR47, Q9H4K0	Gene names	KIAA0406
Domain Architecture	No domain graphic available
Description	Protein KIAA0406.

MBD3_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.010424 (rank : 40)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD3_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.010438 (rank : 39)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2D8, Q792D3, Q8CFJ1	Gene names	Mbd3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

ACHA4_HUMAN
θ value	8.99809 (rank : 25)	NC score	0.002549 (rank : 41)
Query Neighborhood Hits	25	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

CALL5_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.083393 (rank : 33)
Query Neighborhood Hits	25	Target Neighborhood Hits	231	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CALM4_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.063217 (rank : 34)
Query Neighborhood Hits	25	Target Neighborhood Hits	229	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CF103_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.151683 (rank : 32)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

CPNS1_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.496004 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	57	Shared Neighborhood Hits	11
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS1_MOUSE
θ value	θ > 10 (rank : 30)	NC score	0.499585 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS2_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.492174 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CPNS2_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.488639 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

GRAN_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.375216 (rank : 27)
Query Neighborhood Hits	25	Target Neighborhood Hits	57	Shared Neighborhood Hits	11
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

GRAN_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.383809 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VC88, Q8BL53, Q8K3Z6	Gene names	Gca
Domain Architecture	No domain graphic available
Description	Grancalcin.

PDCD6_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.288957 (rank : 30)
Query Neighborhood Hits	25	Target Neighborhood Hits	141	Shared Neighborhood Hits	11
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PDCD6_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.287519 (rank : 31)
Query Neighborhood Hits	25	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

PEF1_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.343907 (rank : 29)
Query Neighborhood Hits	25	Target Neighborhood Hits	135	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PEF1_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.353509 (rank : 28)
Query Neighborhood Hits	25	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

SORCN_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.377823 (rank : 26)
Query Neighborhood Hits	25	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

SORCN_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.380909 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

TNNC1_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.052411 (rank : 35)
Query Neighborhood Hits	25	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

Hits sorted by NC score

CAN5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).

CAN5_HUMAN
NC score	0.999696 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	22
SwissProt Accessions	O15484, O00263	Gene names	CAPN5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3) (htra-3).

CAN6_HUMAN
NC score	0.987784 (rank : 3)	θ value	1.50931e-172 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6Q1, Q9UEQ1, Q9UJA8	Gene names	CAPN6, CALPM, CANPX
Domain Architecture
Description	Calpain-6 (Calpamodulin) (CalpM) (Calpain-like protease X-linked).

CAN6_MOUSE
NC score	0.987233 (rank : 4)	θ value	5.36813e-170 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O35646	Gene names	Capn6, Capa6
Domain Architecture
Description	Calpain-6.

CAN10_MOUSE
NC score	0.936683 (rank : 5)	θ value	1.19377e-60 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN10_HUMAN
NC score	0.933243 (rank : 6)	θ value	4.69435e-57 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC96, Q8NCD4, Q96IG4, Q96JI2, Q9HC89, Q9HC90, Q9HC91, Q9HC92, Q9HC93, Q9HC94, Q9HC95	Gene names	CAPN10, KIAA1845
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN12_HUMAN
NC score	0.918126 (rank : 7)	θ value	1.5519e-76 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CAN12_MOUSE
NC score	0.916393 (rank : 8)	θ value	9.7205e-79 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CAN9_HUMAN
NC score	0.897784 (rank : 9)	θ value	3.4333e-100 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN11_HUMAN
NC score	0.897563 (rank : 10)	θ value	1.94955e-95 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN9_MOUSE
NC score	0.897258 (rank : 11)	θ value	2.46047e-98 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	73	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAN2_HUMAN
NC score	0.895587 (rank : 12)	θ value	1.88391e-98 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN2_MOUSE
NC score	0.892959 (rank : 13)	θ value	4.64023e-97 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CAN1_MOUSE
NC score	0.886146 (rank : 14)	θ value	1.70393e-99 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	83	Shared Neighborhood Hits	19
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN1_HUMAN
NC score	0.885407 (rank : 15)	θ value	1.49272e-95 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN3_HUMAN
NC score	0.880215 (rank : 16)	θ value	1.18001e-100 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CAN3_MOUSE
NC score	0.876250 (rank : 17)	θ value	1.54114e-100 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CAN7_MOUSE
NC score	0.765149 (rank : 18)	θ value	2.05525e-28 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	66	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1S8, Q9Z0P9	Gene names	Capn7, Palbh
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN7_HUMAN
NC score	0.763843 (rank : 19)	θ value	3.50572e-28 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CPNS1_MOUSE
NC score	0.499585 (rank : 20)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	25	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS1_HUMAN
NC score	0.496004 (rank : 21)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	25	Target Neighborhood Hits	57	Shared Neighborhood Hits	11
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS2_HUMAN
NC score	0.492174 (rank : 22)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	25	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CPNS2_MOUSE
NC score	0.488639 (rank : 23)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	25	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

GRAN_MOUSE
NC score	0.383809 (rank : 24)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	25	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VC88, Q8BL53, Q8K3Z6	Gene names	Gca
Domain Architecture	No domain graphic available
Description	Grancalcin.

SORCN_MOUSE
NC score	0.380909 (rank : 25)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	25	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

SORCN_HUMAN
NC score	0.377823 (rank : 26)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	25	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

GRAN_HUMAN
NC score	0.375216 (rank : 27)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	25	Target Neighborhood Hits	57	Shared Neighborhood Hits	11
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

PEF1_MOUSE
NC score	0.353509 (rank : 28)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	25	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PEF1_HUMAN
NC score	0.343907 (rank : 29)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	25	Target Neighborhood Hits	135	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PDCD6_HUMAN
NC score	0.288957 (rank : 30)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	25	Target Neighborhood Hits	141	Shared Neighborhood Hits	11
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PDCD6_MOUSE
NC score	0.287519 (rank : 31)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	25	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

CF103_HUMAN
NC score	0.151683 (rank : 32)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

CALL5_HUMAN
NC score	0.083393 (rank : 33)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	25	Target Neighborhood Hits	231	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CALM4_MOUSE
NC score	0.063217 (rank : 34)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	25	Target Neighborhood Hits	229	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

TNNC1_MOUSE
NC score	0.052411 (rank : 35)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	25	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

FA62A_HUMAN
NC score	0.034800 (rank : 36)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

UN13A_HUMAN
NC score	0.027797 (rank : 37)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	285	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

K0406_HUMAN
NC score	0.014002 (rank : 38)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O43156, Q5JX67, Q96A38, Q9BR47, Q9H4K0	Gene names	KIAA0406
Domain Architecture	No domain graphic available
Description	Protein KIAA0406.

MBD3_MOUSE
NC score	0.010438 (rank : 39)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2D8, Q792D3, Q8CFJ1	Gene names	Mbd3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD3_HUMAN
NC score	0.010424 (rank : 40)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

ACHA4_HUMAN
NC score	0.002549 (rank : 41)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.