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Network neighborhood for query Sequence : CAN12_MOUSE

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CAN12_MOUSE
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAN12_HUMAN
θ value	0 (rank : 1)	NC score	0.998640 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	47	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CAN12_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CAN1_MOUSE
θ value	4.4118e-156 (rank : 3)	NC score	0.976617 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN1_HUMAN
θ value	1.67649e-155 (rank : 4)	NC score	0.976605 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN2_HUMAN
θ value	1.46868e-151 (rank : 5)	NC score	0.981611 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN2_MOUSE
θ value	8.91014e-149 (rank : 6)	NC score	0.980320 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	69	Shared Neighborhood Hits	34
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CAN11_HUMAN
θ value	1.68428e-139 (rank : 7)	NC score	0.982798 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN9_MOUSE
θ value	3.51195e-137 (rank : 8)	NC score	0.977672 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAN3_HUMAN
θ value	8.37844e-131 (rank : 9)	NC score	0.971614 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	96	Shared Neighborhood Hits	39
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CAN3_MOUSE
θ value	1.86652e-130 (rank : 10)	NC score	0.967988 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CAN9_HUMAN
θ value	7.09276e-130 (rank : 11)	NC score	0.977935 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN5_MOUSE
θ value	9.7205e-79 (rank : 12)	NC score	0.916393 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).

CAN5_HUMAN
θ value	5.51964e-74 (rank : 13)	NC score	0.914905 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	O15484, O00263	Gene names	CAPN5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3) (htra-3).

CAN6_HUMAN
θ value	7.47731e-63 (rank : 14)	NC score	0.902517 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6Q1, Q9UEQ1, Q9UJA8	Gene names	CAPN6, CALPM, CANPX
Domain Architecture
Description	Calpain-6 (Calpamodulin) (CalpM) (Calpain-like protease X-linked).

CAN6_MOUSE
θ value	1.07972e-61 (rank : 15)	NC score	0.901330 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O35646	Gene names	Capn6, Capa6
Domain Architecture
Description	Calpain-6.

CAN10_MOUSE
θ value	2.94036e-59 (rank : 16)	NC score	0.900538 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN10_HUMAN
θ value	3.84025e-59 (rank : 17)	NC score	0.897726 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC96, Q8NCD4, Q96IG4, Q96JI2, Q9HC89, Q9HC90, Q9HC91, Q9HC92, Q9HC93, Q9HC94, Q9HC95	Gene names	CAPN10, KIAA1845
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CPNS1_MOUSE
θ value	5.42112e-21 (rank : 18)	NC score	0.754256 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS1_HUMAN
θ value	2.69047e-20 (rank : 19)	NC score	0.752071 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS2_HUMAN
θ value	2.97466e-19 (rank : 20)	NC score	0.747985 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CAN7_MOUSE
θ value	3.40345e-15 (rank : 21)	NC score	0.687483 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1S8, Q9Z0P9	Gene names	Capn7, Palbh
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CPNS2_MOUSE
θ value	9.90251e-15 (rank : 22)	NC score	0.743355 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CAN7_HUMAN
θ value	2.20605e-14 (rank : 23)	NC score	0.684473 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

SORCN_MOUSE
θ value	1.58096e-12 (rank : 24)	NC score	0.643396 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

SORCN_HUMAN
θ value	2.28291e-11 (rank : 25)	NC score	0.637787 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	82	Shared Neighborhood Hits	41
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

GRAN_MOUSE
θ value	5.08577e-11 (rank : 26)	NC score	0.644758 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VC88, Q8BL53, Q8K3Z6	Gene names	Gca
Domain Architecture	No domain graphic available
Description	Grancalcin.

GRAN_HUMAN
θ value	3.29651e-10 (rank : 27)	NC score	0.634439 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	57	Shared Neighborhood Hits	32
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

PEF1_HUMAN
θ value	6.21693e-09 (rank : 28)	NC score	0.590745 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PEF1_MOUSE
θ value	1.06045e-08 (rank : 29)	NC score	0.601856 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	112	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PDCD6_HUMAN
θ value	4.45536e-07 (rank : 30)	NC score	0.511999 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	141	Shared Neighborhood Hits	31
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PDCD6_MOUSE
θ value	4.45536e-07 (rank : 31)	NC score	0.510127 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	142	Shared Neighborhood Hits	31
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

CETN1_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.103262 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	232	Shared Neighborhood Hits	43
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN1_MOUSE
θ value	0.47712 (rank : 33)	NC score	0.090835 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	231	Shared Neighborhood Hits	40
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

CALL5_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.155305 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	231	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

MLE1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.041454 (rank : 65)
Query Neighborhood Hits	56	Target Neighborhood Hits	64	Shared Neighborhood Hits	21
SwissProt Accessions	P05976	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE1_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.042895 (rank : 63)
Query Neighborhood Hits	56	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	P05977	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE3_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.041266 (rank : 66)
Query Neighborhood Hits	56	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	P06741	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MLE3_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.042772 (rank : 64)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	P05978	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MYL3_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.039861 (rank : 68)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	P08590, Q9NRS8	Gene names	MYL3
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain) (Cardiac myosin light chain-1) (CMLC1).

MYL3_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.039592 (rank : 69)
Query Neighborhood Hits	56	Target Neighborhood Hits	70	Shared Neighborhood Hits	22
SwissProt Accessions	P09542, Q3UIF4, Q9CQZ2	Gene names	Myl3, Mlc1v, Mylc
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain).

MYL6_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.043985 (rank : 61)
Query Neighborhood Hits	56	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	P60660, P16475, P24572, P24573, Q12790, Q6IAZ0, Q6IPY5	Gene names	MYL6
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

MYL6_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.043985 (rank : 62)
Query Neighborhood Hits	56	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	Q60605	Gene names	Myl6, Myln
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

CETN2_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.085645 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	211	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CF103_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.139817 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

SPEG_HUMAN
θ value	2.36792 (rank : 45)	NC score	-0.001378 (rank : 76)
Query Neighborhood Hits	56	Target Neighborhood Hits	1762	Shared Neighborhood Hits	4
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CETN2_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.080111 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

MYL4_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.040732 (rank : 67)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	22
SwissProt Accessions	P09541	Gene names	Myl4, Mlc1a, Myla
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, atrial/fetal isoform) (MLC1A) (MLC1EMB).

MYL6B_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.045058 (rank : 60)
Query Neighborhood Hits	56	Target Neighborhood Hits	78	Shared Neighborhood Hits	24
SwissProt Accessions	P14649	Gene names	MYL6B, MLC1SA
Domain Architecture
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B) (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa).

ATS2_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.001392 (rank : 75)
Query Neighborhood Hits	56	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

MYL6B_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.037817 (rank : 70)
Query Neighborhood Hits	56	Target Neighborhood Hits	68	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CI43	Gene names	Myl6b
Domain Architecture	No domain graphic available
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B).

ACTN1_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.014761 (rank : 73)
Query Neighborhood Hits	56	Target Neighborhood Hits	221	Shared Neighborhood Hits	18
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.015399 (rank : 72)
Query Neighborhood Hits	56	Target Neighborhood Hits	216	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

CALL3_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.093396 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	225	Shared Neighborhood Hits	35
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

SPEG_MOUSE
θ value	6.88961 (rank : 54)	NC score	-0.002312 (rank : 77)
Query Neighborhood Hits	56	Target Neighborhood Hits	1959	Shared Neighborhood Hits	5
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

COA1_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.003987 (rank : 74)
Query Neighborhood Hits	56	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

MYL4_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.036412 (rank : 71)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	P12829, P11783	Gene names	MYL4, MLC1
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali, GT-1 isoform).

CABP1_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.050818 (rank : 59)
Query Neighborhood Hits	56	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CABP1_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.051277 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CABP2_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.052103 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP4_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.076343 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	250	Shared Neighborhood Hits	37
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CABP7_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.052643 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.052643 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CALB1_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.053587 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	130	Shared Neighborhood Hits	15
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CALB1_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.058308 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	129	Shared Neighborhood Hits	15
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

CALB2_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.061071 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALM4_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.120779 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	229	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CALM_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.096953 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	232	Shared Neighborhood Hits	36
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.096953 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	232	Shared Neighborhood Hits	36
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CANB1_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.051233 (rank : 58)
Query Neighborhood Hits	56	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.051238 (rank : 57)
Query Neighborhood Hits	56	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CETN3_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.061278 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	211	Shared Neighborhood Hits	36
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.061591 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

PLSI_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.064333 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	209	Shared Neighborhood Hits	25
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

TNNC1_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.086973 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC1_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.092353 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	221	Shared Neighborhood Hits	38
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC2_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.069935 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	234	Shared Neighborhood Hits	38
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

TNNC2_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.073772 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	233	Shared Neighborhood Hits	38
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

Hits sorted by NC score

CAN12_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CAN12_HUMAN
NC score	0.998640 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	47	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZSI9	Gene names	CAPN12
Domain Architecture	No domain graphic available
Description	Calpain-12 (EC 3.4.22.-).

CAN11_HUMAN
NC score	0.982798 (rank : 3)	θ value	1.68428e-139 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN2_HUMAN
NC score	0.981611 (rank : 4)	θ value	1.46868e-151 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN2_MOUSE
NC score	0.980320 (rank : 5)	θ value	8.91014e-149 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	69	Shared Neighborhood Hits	34
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CAN9_HUMAN
NC score	0.977935 (rank : 6)	θ value	7.09276e-130 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN9_MOUSE
NC score	0.977672 (rank : 7)	θ value	3.51195e-137 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAN1_MOUSE
NC score	0.976617 (rank : 8)	θ value	4.4118e-156 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN1_HUMAN
NC score	0.976605 (rank : 9)	θ value	1.67649e-155 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CAN3_HUMAN
NC score	0.971614 (rank : 10)	θ value	8.37844e-131 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	96	Shared Neighborhood Hits	39
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CAN3_MOUSE
NC score	0.967988 (rank : 11)	θ value	1.86652e-130 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CAN5_MOUSE
NC score	0.916393 (rank : 12)	θ value	9.7205e-79 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	O08688, Q91YU0	Gene names	Capn5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3).

CAN5_HUMAN
NC score	0.914905 (rank : 13)	θ value	5.51964e-74 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	O15484, O00263	Gene names	CAPN5
Domain Architecture
Description	Calpain-5 (EC 3.4.22.-) (nCL-3) (htra-3).

CAN6_HUMAN
NC score	0.902517 (rank : 14)	θ value	7.47731e-63 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6Q1, Q9UEQ1, Q9UJA8	Gene names	CAPN6, CALPM, CANPX
Domain Architecture
Description	Calpain-6 (Calpamodulin) (CalpM) (Calpain-like protease X-linked).

CAN6_MOUSE
NC score	0.901330 (rank : 15)	θ value	1.07972e-61 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O35646	Gene names	Capn6, Capa6
Domain Architecture
Description	Calpain-6.

CAN10_MOUSE
NC score	0.900538 (rank : 16)	θ value	2.94036e-59 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAN10_HUMAN
NC score	0.897726 (rank : 17)	θ value	3.84025e-59 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC96, Q8NCD4, Q96IG4, Q96JI2, Q9HC89, Q9HC90, Q9HC91, Q9HC92, Q9HC93, Q9HC94, Q9HC95	Gene names	CAPN10, KIAA1845
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CPNS1_MOUSE
NC score	0.754256 (rank : 18)	θ value	5.42112e-21 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS1_HUMAN
NC score	0.752071 (rank : 19)	θ value	2.69047e-20 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CPNS2_HUMAN
NC score	0.747985 (rank : 20)	θ value	2.97466e-19 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CPNS2_MOUSE
NC score	0.743355 (rank : 21)	θ value	9.90251e-15 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CAN7_MOUSE
NC score	0.687483 (rank : 22)	θ value	3.40345e-15 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1S8, Q9Z0P9	Gene names	Capn7, Palbh
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

CAN7_HUMAN
NC score	0.684473 (rank : 23)	θ value	2.20605e-14 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

GRAN_MOUSE
NC score	0.644758 (rank : 24)	θ value	5.08577e-11 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VC88, Q8BL53, Q8K3Z6	Gene names	Gca
Domain Architecture	No domain graphic available
Description	Grancalcin.

SORCN_MOUSE
NC score	0.643396 (rank : 25)	θ value	1.58096e-12 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

SORCN_HUMAN
NC score	0.637787 (rank : 26)	θ value	2.28291e-11 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	82	Shared Neighborhood Hits	41
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

GRAN_HUMAN
NC score	0.634439 (rank : 27)	θ value	3.29651e-10 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	57	Shared Neighborhood Hits	32
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

PEF1_MOUSE
NC score	0.601856 (rank : 28)	θ value	1.06045e-08 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	112	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PEF1_HUMAN
NC score	0.590745 (rank : 29)	θ value	6.21693e-09 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PDCD6_HUMAN
NC score	0.511999 (rank : 30)	θ value	4.45536e-07 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	141	Shared Neighborhood Hits	31
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PDCD6_MOUSE
NC score	0.510127 (rank : 31)	θ value	4.45536e-07 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	142	Shared Neighborhood Hits	31
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

CALL5_HUMAN
NC score	0.155305 (rank : 32)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	231	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CF103_HUMAN
NC score	0.139817 (rank : 33)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N7X0, Q5T402	Gene names	C6orf103
Domain Architecture	No domain graphic available
Description	Protein C6orf103.

CALM4_MOUSE
NC score	0.120779 (rank : 34)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	56	Target Neighborhood Hits	229	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CETN1_HUMAN
NC score	0.103262 (rank : 35)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	232	Shared Neighborhood Hits	43
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CALM_HUMAN
NC score	0.096953 (rank : 36)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	56	Target Neighborhood Hits	232	Shared Neighborhood Hits	36
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.096953 (rank : 37)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	56	Target Neighborhood Hits	232	Shared Neighborhood Hits	36
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CALL3_HUMAN
NC score	0.093396 (rank : 38)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	225	Shared Neighborhood Hits	35
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

TNNC1_MOUSE
NC score	0.092353 (rank : 39)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	56	Target Neighborhood Hits	221	Shared Neighborhood Hits	38
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CETN1_MOUSE
NC score	0.090835 (rank : 40)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	231	Shared Neighborhood Hits	40
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

TNNC1_HUMAN
NC score	0.086973 (rank : 41)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	56	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CETN2_MOUSE
NC score	0.085645 (rank : 42)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	211	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN2_HUMAN
NC score	0.080111 (rank : 43)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CABP4_HUMAN
NC score	0.076343 (rank : 44)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	56	Target Neighborhood Hits	250	Shared Neighborhood Hits	37
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

TNNC2_MOUSE
NC score	0.073772 (rank : 45)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	56	Target Neighborhood Hits	233	Shared Neighborhood Hits	38
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

TNNC2_HUMAN
NC score	0.069935 (rank : 46)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	56	Target Neighborhood Hits	234	Shared Neighborhood Hits	38
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

PLSI_HUMAN
NC score	0.064333 (rank : 47)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	56	Target Neighborhood Hits	209	Shared Neighborhood Hits	25
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

CETN3_MOUSE
NC score	0.061591 (rank : 48)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	56	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

CETN3_HUMAN
NC score	0.061278 (rank : 49)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	56	Target Neighborhood Hits	211	Shared Neighborhood Hits	36
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CALB2_HUMAN
NC score	0.061071 (rank : 50)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	56	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB1_MOUSE
NC score	0.058308 (rank : 51)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	56	Target Neighborhood Hits	129	Shared Neighborhood Hits	15
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

CALB1_HUMAN
NC score	0.053587 (rank : 52)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	56	Target Neighborhood Hits	130	Shared Neighborhood Hits	15
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CABP7_HUMAN
NC score	0.052643 (rank : 53)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	56	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
NC score	0.052643 (rank : 54)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	56	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP2_MOUSE
NC score	0.052103 (rank : 55)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	56	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP1_MOUSE
NC score	0.051277 (rank : 56)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	56	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CANB1_MOUSE
NC score	0.051238 (rank : 57)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	56	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_HUMAN
NC score	0.051233 (rank : 58)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	56	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CABP1_HUMAN
NC score	0.050818 (rank : 59)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	56	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

MYL6B_HUMAN
NC score	0.045058 (rank : 60)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	78	Shared Neighborhood Hits	24
SwissProt Accessions	P14649	Gene names	MYL6B, MLC1SA
Domain Architecture
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B) (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa).

MYL6_HUMAN
NC score	0.043985 (rank : 61)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	P60660, P16475, P24572, P24573, Q12790, Q6IAZ0, Q6IPY5	Gene names	MYL6
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

MYL6_MOUSE
NC score	0.043985 (rank : 62)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	Q60605	Gene names	Myl6, Myln
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

MLE1_MOUSE
NC score	0.042895 (rank : 63)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	P05977	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE3_MOUSE
NC score	0.042772 (rank : 64)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	P05978	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MLE1_HUMAN
NC score	0.041454 (rank : 65)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	64	Shared Neighborhood Hits	21
SwissProt Accessions	P05976	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE3_HUMAN
NC score	0.041266 (rank : 66)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	P06741	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MYL4_MOUSE
NC score	0.040732 (rank : 67)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	22
SwissProt Accessions	P09541	Gene names	Myl4, Mlc1a, Myla
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, atrial/fetal isoform) (MLC1A) (MLC1EMB).

MYL3_HUMAN
NC score	0.039861 (rank : 68)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	P08590, Q9NRS8	Gene names	MYL3
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain) (Cardiac myosin light chain-1) (CMLC1).

MYL3_MOUSE
NC score	0.039592 (rank : 69)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	70	Shared Neighborhood Hits	22
SwissProt Accessions	P09542, Q3UIF4, Q9CQZ2	Gene names	Myl3, Mlc1v, Mylc
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain).

MYL6B_MOUSE
NC score	0.037817 (rank : 70)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	68	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CI43	Gene names	Myl6b
Domain Architecture	No domain graphic available
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B).

MYL4_HUMAN
NC score	0.036412 (rank : 71)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	P12829, P11783	Gene names	MYL4, MLC1
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali, GT-1 isoform).

ACTN1_MOUSE
NC score	0.015399 (rank : 72)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	216	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_HUMAN
NC score	0.014761 (rank : 73)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	221	Shared Neighborhood Hits	18
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

COA1_HUMAN
NC score	0.003987 (rank : 74)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

ATS2_HUMAN
NC score	0.001392 (rank : 75)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	179	Shared Neighborhood Hits	2
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

SPEG_HUMAN
NC score	-0.001378 (rank : 76)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	1762	Shared Neighborhood Hits	4
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
NC score	-0.002312 (rank : 77)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	1959	Shared Neighborhood Hits	5
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).