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Network neighborhood for query Sequence : RN139_MOUSE

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RN139_MOUSE
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RN139_HUMAN
θ value	0 (rank : 1)	NC score	0.994303 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	130	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

ZN364_MOUSE
θ value	2.13673e-09 (rank : 3)	NC score	0.566775 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	140	Shared Neighborhood Hits	92
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZN364_HUMAN
θ value	4.76016e-09 (rank : 4)	NC score	0.569326 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	140	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

RNF13_MOUSE
θ value	1.06045e-08 (rank : 5)	NC score	0.550504 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	164	Shared Neighborhood Hits	89
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF13_HUMAN
θ value	5.81887e-07 (rank : 6)	NC score	0.528983 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	147	Shared Neighborhood Hits	83
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

DZIP3_HUMAN
θ value	1.29631e-06 (rank : 7)	NC score	0.406488 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	399	Shared Neighborhood Hits	93
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RN122_HUMAN
θ value	1.69304e-06 (rank : 8)	NC score	0.569373 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

AMFR2_HUMAN
θ value	4.92598e-06 (rank : 9)	NC score	0.471792 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	219	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RN122_MOUSE
θ value	4.92598e-06 (rank : 10)	NC score	0.565940 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF24_HUMAN
θ value	4.92598e-06 (rank : 11)	NC score	0.554950 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	4.92598e-06 (rank : 12)	NC score	0.555990 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	124	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

AMFR_MOUSE
θ value	6.43352e-06 (rank : 13)	NC score	0.472861 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	208	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

DZIP3_MOUSE
θ value	6.43352e-06 (rank : 14)	NC score	0.406824 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	414	Shared Neighborhood Hits	92
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

GOLI_HUMAN
θ value	8.40245e-06 (rank : 15)	NC score	0.524327 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RNF38_HUMAN
θ value	8.40245e-06 (rank : 16)	NC score	0.518889 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	155	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF38_MOUSE
θ value	8.40245e-06 (rank : 17)	NC score	0.515082 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	153	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

GOLI_MOUSE
θ value	1.09739e-05 (rank : 18)	NC score	0.526719 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	134	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

RNF6_HUMAN
θ value	1.09739e-05 (rank : 19)	NC score	0.504418 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	157	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RN167_MOUSE
θ value	3.19293e-05 (rank : 20)	NC score	0.511909 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	157	Shared Neighborhood Hits	89
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_HUMAN
θ value	4.1701e-05 (rank : 21)	NC score	0.511408 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	157	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

PJA1_HUMAN
θ value	7.1131e-05 (rank : 22)	NC score	0.469434 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	159	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	7.1131e-05 (rank : 23)	NC score	0.479321 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	145	Shared Neighborhood Hits	87
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RN126_HUMAN
θ value	7.1131e-05 (rank : 24)	NC score	0.507445 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	126	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	7.1131e-05 (rank : 25)	NC score	0.517430 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	143	Shared Neighborhood Hits	95
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RNF12_MOUSE
θ value	7.1131e-05 (rank : 26)	NC score	0.502888 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	159	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF12_HUMAN
θ value	0.000158464 (rank : 27)	NC score	0.483247 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	173	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RAD18_HUMAN
θ value	0.00020696 (rank : 28)	NC score	0.285204 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	284	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	0.00035302 (rank : 29)	NC score	0.285784 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	230	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RN133_HUMAN
θ value	0.000461057 (rank : 30)	NC score	0.516818 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	108	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RN165_HUMAN
θ value	0.000461057 (rank : 31)	NC score	0.524793 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	151	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

TTC3_HUMAN
θ value	0.00102713 (rank : 32)	NC score	0.250855 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	664	Shared Neighborhood Hits	74
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

RN175_HUMAN
θ value	0.00298849 (rank : 33)	NC score	0.350583 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

TOPRS_HUMAN
θ value	0.00665767 (rank : 34)	NC score	0.284732 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	286	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ZSWM2_MOUSE
θ value	0.00665767 (rank : 35)	NC score	0.346703 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	132	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RNF11_HUMAN
θ value	0.0113563 (rank : 36)	NC score	0.478041 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	0.0113563 (rank : 37)	NC score	0.476495 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

DTX3_HUMAN
θ value	0.0252991 (rank : 38)	NC score	0.216473 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

MYCB2_HUMAN
θ value	0.0252991 (rank : 39)	NC score	0.132217 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	390	Shared Neighborhood Hits	41
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
θ value	0.0252991 (rank : 40)	NC score	0.135518 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

LNX1_HUMAN
θ value	0.0330416 (rank : 41)	NC score	0.122050 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	379	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TOPRS_MOUSE
θ value	0.0330416 (rank : 42)	NC score	0.276585 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	263	Shared Neighborhood Hits	99
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

APC11_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.287995 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

DTX3_MOUSE
θ value	0.0431538 (rank : 44)	NC score	0.210017 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	202	Shared Neighborhood Hits	73
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

ZSWM2_HUMAN
θ value	0.0431538 (rank : 45)	NC score	0.310747 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

BRAP_HUMAN
θ value	0.0563607 (rank : 46)	NC score	0.191515 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	560	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	0.0563607 (rank : 47)	NC score	0.215665 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

DTX3L_HUMAN
θ value	0.0563607 (rank : 48)	NC score	0.203584 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	187	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

LNX2_HUMAN
θ value	0.0563607 (rank : 49)	NC score	0.129770 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	389	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RNF4_HUMAN
θ value	0.0563607 (rank : 50)	NC score	0.283303 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	212	Shared Neighborhood Hits	94
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	0.0563607 (rank : 51)	NC score	0.279912 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	212	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF8_MOUSE
θ value	0.0563607 (rank : 52)	NC score	0.248377 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	618	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

LNX2_MOUSE
θ value	0.0736092 (rank : 53)	NC score	0.129254 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	407	Shared Neighborhood Hits	81
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PCGF2_HUMAN
θ value	0.0736092 (rank : 54)	NC score	0.212998 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	222	Shared Neighborhood Hits	71
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	0.0736092 (rank : 55)	NC score	0.213402 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

RNF32_HUMAN
θ value	0.0736092 (rank : 56)	NC score	0.306982 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	133	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF8_HUMAN
θ value	0.0736092 (rank : 57)	NC score	0.238299 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	622	Shared Neighborhood Hits	104
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRIM3_HUMAN
θ value	0.0736092 (rank : 58)	NC score	0.137119 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	357	Shared Neighborhood Hits	85
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

APC11_MOUSE
θ value	0.0961366 (rank : 59)	NC score	0.283846 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

GP110_MOUSE
θ value	0.0961366 (rank : 60)	NC score	0.039985 (rank : 169)
Query Neighborhood Hits	131	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

CBLC_HUMAN
θ value	0.125558 (rank : 61)	NC score	0.147639 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	173	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

LNX1_MOUSE
θ value	0.125558 (rank : 62)	NC score	0.114103 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	377	Shared Neighborhood Hits	67
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RBX2_HUMAN
θ value	0.125558 (rank : 63)	NC score	0.324888 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	83	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	0.125558 (rank : 64)	NC score	0.325503 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	82	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RNF32_MOUSE
θ value	0.125558 (rank : 65)	NC score	0.295479 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

TRIM3_MOUSE
θ value	0.125558 (rank : 66)	NC score	0.130935 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

PEX10_HUMAN
θ value	0.21417 (rank : 67)	NC score	0.290040 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	255	Shared Neighborhood Hits	105
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RBBP6_HUMAN
θ value	0.21417 (rank : 68)	NC score	0.086473 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.21417 (rank : 69)	NC score	0.098360 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	1014	Shared Neighborhood Hits	51
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

MC5R_HUMAN
θ value	0.279714 (rank : 70)	NC score	0.008958 (rank : 176)
Query Neighborhood Hits	131	Target Neighborhood Hits	903	Shared Neighborhood Hits	5
SwissProt Accessions	P33032	Gene names	MC5R
Domain Architecture
Description	Melanocortin receptor 5 (MC5-R) (MC-2).

PZRN3_HUMAN
θ value	0.279714 (rank : 71)	NC score	0.122008 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	461	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.279714 (rank : 72)	NC score	0.122359 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	447	Shared Neighborhood Hits	75
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAIP_MOUSE
θ value	0.279714 (rank : 73)	NC score	0.149758 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	745	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

ZN363_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.266714 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	162	Shared Neighborhood Hits	50
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	0.279714 (rank : 75)	NC score	0.273996 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	134	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

RFWD2_HUMAN
θ value	0.365318 (rank : 76)	NC score	0.115764 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	518	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	0.365318 (rank : 77)	NC score	0.115809 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	535	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

PCGF6_HUMAN
θ value	0.47712 (rank : 78)	NC score	0.164413 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	0.47712 (rank : 79)	NC score	0.163709 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI35_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.092498 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	382	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

RN103_HUMAN
θ value	0.62314 (rank : 81)	NC score	0.304756 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	0.62314 (rank : 82)	NC score	0.307433 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	143	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

CHFR_HUMAN
θ value	0.813845 (rank : 83)	NC score	0.252291 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	255	Shared Neighborhood Hits	88
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	0.813845 (rank : 84)	NC score	0.257866 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	88
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

PCGF4_HUMAN
θ value	0.813845 (rank : 85)	NC score	0.192092 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	0.813845 (rank : 86)	NC score	0.191445 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	163	Shared Neighborhood Hits	69
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RBX1_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.236442 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
θ value	1.06291 (rank : 88)	NC score	0.236442 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

RNF25_HUMAN
θ value	1.06291 (rank : 89)	NC score	0.148474 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RNF25_MOUSE
θ value	1.06291 (rank : 90)	NC score	0.157628 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RNF41_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.205124 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	226	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	1.06291 (rank : 92)	NC score	0.205239 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	224	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRIM2_HUMAN
θ value	1.06291 (rank : 93)	NC score	0.141211 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	330	Shared Neighborhood Hits	87
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.140695 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	331	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

MARH2_HUMAN
θ value	1.38821 (rank : 95)	NC score	0.053628 (rank : 161)
Query Neighborhood Hits	131	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0N8, Q8N5A3, Q96B78	Gene names	MARCH2, RNF172
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 2 (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172).

TRAIP_HUMAN
θ value	1.38821 (rank : 96)	NC score	0.141991 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	780	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRI65_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.126110 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	330	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CBLC_MOUSE
θ value	1.81305 (rank : 98)	NC score	0.148974 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.121074 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	426	Shared Neighborhood Hits	72
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

MKRN3_MOUSE
θ value	1.81305 (rank : 100)	NC score	0.079161 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	137	Shared Neighborhood Hits	44
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

R113A_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.108736 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

ZN294_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.101006 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

ZN294_MOUSE
θ value	1.81305 (rank : 103)	NC score	0.101396 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

CBL_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.123038 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	353	Shared Neighborhood Hits	70
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

MARH2_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.056925 (rank : 159)
Query Neighborhood Hits	131	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q99M02, Q8C4Q5	Gene names	March2
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 2 (Membrane-associated RING-CH protein II) (MARCH-II).

R113B_HUMAN
θ value	2.36792 (rank : 106)	NC score	0.095613 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RN123_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.074217 (rank : 135)
Query Neighborhood Hits	131	Target Neighborhood Hits	175	Shared Neighborhood Hits	48
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRI25_MOUSE
θ value	2.36792 (rank : 108)	NC score	0.077974 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	446	Shared Neighborhood Hits	66
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

APH1B_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.026353 (rank : 170)
Query Neighborhood Hits	131	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C7N7, Q3U3B5, Q8CEC9	Gene names	Aph1b
Domain Architecture
Description	Gamma-secretase subunit APH-1B (APH-1b) (Aph-1beta).

APH1C_MOUSE
θ value	3.0926 (rank : 110)	NC score	0.026131 (rank : 171)
Query Neighborhood Hits	131	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCZ9, Q3U2R3	Gene names	Aph1c
Domain Architecture
Description	Putative gamma-secretase subunit APH-1C.

GCP3_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.023536 (rank : 172)
Query Neighborhood Hits	131	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CW5, O43631, O60852, O60853, Q7Z4K1, Q96I79	Gene names	TUBGCP3, GCP3
Domain Architecture
Description	Gamma-tubulin complex component 3 (GCP-3) (Spindle pole body protein Spc98 homolog) (hSpc98) (hGCP3) (h104p).

MKRN4_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.069491 (rank : 138)
Query Neighborhood Hits	131	Target Neighborhood Hits	147	Shared Neighborhood Hits	50
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

RN146_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.099115 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.098101 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	161	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

SALL2_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.000110 (rank : 180)
Query Neighborhood Hits	131	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

TRI25_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.073574 (rank : 136)
Query Neighborhood Hits	131	Target Neighborhood Hits	472	Shared Neighborhood Hits	64
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

CCR5_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.002625 (rank : 178)
Query Neighborhood Hits	131	Target Neighborhood Hits	633	Shared Neighborhood Hits	5
SwissProt Accessions	P51682, O35313, O35891, P97308, P97405, Q61867	Gene names	Ccr5, Cmkbr5
Domain Architecture
Description	C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (MIP-1 alpha receptor) (CD195 antigen).

DSPP_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.021218 (rank : 173)
Query Neighborhood Hits	131	Target Neighborhood Hits	645	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.008895 (rank : 177)
Query Neighborhood Hits	131	Target Neighborhood Hits	958	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MKRN3_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.063909 (rank : 143)
Query Neighborhood Hits	131	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RN141_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.309674 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	199	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.310855 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	200	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

CCR2_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.002096 (rank : 179)
Query Neighborhood Hits	131	Target Neighborhood Hits	631	Shared Neighborhood Hits	5
SwissProt Accessions	P51683, Q61172	Gene names	Ccr2, Cmkbr2
Domain Architecture
Description	C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC receptor) (MCP-1 receptor) (CD192 antigen).

CM007_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.135464 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	416	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CM007_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.123280 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	422	Shared Neighborhood Hits	78
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

GCP3_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.019047 (rank : 174)
Query Neighborhood Hits	131	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P58854, Q6PDQ9	Gene names	Tubgcp3, Gcp3
Domain Architecture	No domain graphic available
Description	Gamma-tubulin complex component 3 (GCP-3).

MKRN1_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.065089 (rank : 141)
Query Neighborhood Hits	131	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.061769 (rank : 150)
Query Neighborhood Hits	131	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

PZRN4_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.088890 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	438	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RN123_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.063442 (rank : 145)
Query Neighborhood Hits	131	Target Neighborhood Hits	174	Shared Neighborhood Hits	47
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

UBF1_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.011586 (rank : 175)
Query Neighborhood Hits	131	Target Neighborhood Hits	415	Shared Neighborhood Hits	6
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

AMFR1_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.059680 (rank : 155)
Query Neighborhood Hits	131	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P26442	Gene names	AMFR
Domain Architecture	No domain graphic available
Description	Autocrine motility factor receptor precursor, isoform 1 (AMF receptor).

BFAR_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.080546 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	222	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.082935 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	232	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRCA1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.060385 (rank : 153)
Query Neighborhood Hits	131	Target Neighborhood Hits	381	Shared Neighborhood Hits	61
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.056658 (rank : 160)
Query Neighborhood Hits	131	Target Neighborhood Hits	436	Shared Neighborhood Hits	58
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

CBLB_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.107294 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	261	Shared Neighborhood Hits	63
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.106965 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

MGRN1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.064786 (rank : 142)
Query Neighborhood Hits	131	Target Neighborhood Hits	192	Shared Neighborhood Hits	45
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.062877 (rank : 146)
Query Neighborhood Hits	131	Target Neighborhood Hits	149	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RAPSN_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.113402 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	84	Shared Neighborhood Hits	45
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.111716 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RING1_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.103210 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	219	Shared Neighborhood Hits	54
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.101213 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	54
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.096002 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	201	Shared Neighborhood Hits	57
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.095963 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	199	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN125_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.088039 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	230	Shared Neighborhood Hits	63
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.077465 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN166_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.079278 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.080212 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	248	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.057996 (rank : 158)
Query Neighborhood Hits	131	Target Neighborhood Hits	370	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.063503 (rank : 144)
Query Neighborhood Hits	131	Target Neighborhood Hits	440	Shared Neighborhood Hits	56
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN185_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.130843 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	213	Shared Neighborhood Hits	83
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.128513 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	211	Shared Neighborhood Hits	81
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF5_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.102703 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	206	Shared Neighborhood Hits	73
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.102585 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	206	Shared Neighborhood Hits	74
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

SMRA3_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.051556 (rank : 165)
Query Neighborhood Hits	131	Target Neighborhood Hits	265	Shared Neighborhood Hits	64
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI13_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.082928 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	274	Shared Neighborhood Hits	82
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.085347 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	282	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI26_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.051354 (rank : 166)
Query Neighborhood Hits	131	Target Neighborhood Hits	335	Shared Neighborhood Hits	69
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.052837 (rank : 164)
Query Neighborhood Hits	131	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI31_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.058452 (rank : 157)
Query Neighborhood Hits	131	Target Neighborhood Hits	299	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI35_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.074250 (rank : 134)
Query Neighborhood Hits	131	Target Neighborhood Hits	465	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.061566 (rank : 151)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.061195 (rank : 152)
Query Neighborhood Hits	131	Target Neighborhood Hits	316	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI39_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.062773 (rank : 147)
Query Neighborhood Hits	131	Target Neighborhood Hits	693	Shared Neighborhood Hits	92
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.062085 (rank : 149)
Query Neighborhood Hits	131	Target Neighborhood Hits	691	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI40_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.070716 (rank : 137)
Query Neighborhood Hits	131	Target Neighborhood Hits	279	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI56_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.062115 (rank : 148)
Query Neighborhood Hits	131	Target Neighborhood Hits	339	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.053291 (rank : 163)
Query Neighborhood Hits	131	Target Neighborhood Hits	255	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI59_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.067348 (rank : 140)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.068443 (rank : 139)
Query Neighborhood Hits	131	Target Neighborhood Hits	292	Shared Neighborhood Hits	69
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI65_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.108008 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	340	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI73_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.053468 (rank : 162)
Query Neighborhood Hits	131	Target Neighborhood Hits	258	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.051023 (rank : 167)
Query Neighborhood Hits	131	Target Neighborhood Hits	249	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM8_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.050500 (rank : 168)
Query Neighborhood Hits	131	Target Neighborhood Hits	650	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

VPS11_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.059253 (rank : 156)
Query Neighborhood Hits	131	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

VPS11_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.059972 (rank : 154)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

ZN313_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.109146 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.105087 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	273	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

RN139_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN139_HUMAN
NC score	0.994303 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	130	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN122_HUMAN
NC score	0.569373 (rank : 3)	θ value	1.69304e-06 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

ZN364_HUMAN
NC score	0.569326 (rank : 4)	θ value	4.76016e-09 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	140	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
NC score	0.566775 (rank : 5)	θ value	2.13673e-09 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	140	Shared Neighborhood Hits	92
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RN122_MOUSE
NC score	0.565940 (rank : 6)	θ value	4.92598e-06 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF24_MOUSE
NC score	0.555990 (rank : 7)	θ value	4.92598e-06 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	124	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.554950 (rank : 8)	θ value	4.92598e-06 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF13_MOUSE
NC score	0.550504 (rank : 9)	θ value	1.06045e-08 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	164	Shared Neighborhood Hits	89
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF13_HUMAN
NC score	0.528983 (rank : 10)	θ value	5.81887e-07 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	147	Shared Neighborhood Hits	83
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

GOLI_MOUSE
NC score	0.526719 (rank : 11)	θ value	1.09739e-05 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	134	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

RN165_HUMAN
NC score	0.524793 (rank : 12)	θ value	0.000461057 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	151	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

GOLI_HUMAN
NC score	0.524327 (rank : 13)	θ value	8.40245e-06 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RNF38_HUMAN
NC score	0.518889 (rank : 14)	θ value	8.40245e-06 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	155	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN126_MOUSE
NC score	0.517430 (rank : 15)	θ value	7.1131e-05 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	143	Shared Neighborhood Hits	95
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN133_HUMAN
NC score	0.516818 (rank : 16)	θ value	0.000461057 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	108	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RNF38_MOUSE
NC score	0.515082 (rank : 17)	θ value	8.40245e-06 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	153	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN167_MOUSE
NC score	0.511909 (rank : 18)	θ value	3.19293e-05 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	157	Shared Neighborhood Hits	89
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_HUMAN
NC score	0.511408 (rank : 19)	θ value	4.1701e-05 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	157	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN126_HUMAN
NC score	0.507445 (rank : 20)	θ value	7.1131e-05 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	126	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RNF6_HUMAN
NC score	0.504418 (rank : 21)	θ value	1.09739e-05 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	157	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF12_MOUSE
NC score	0.502888 (rank : 22)	θ value	7.1131e-05 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	159	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF12_HUMAN
NC score	0.483247 (rank : 23)	θ value	0.000158464 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	173	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

PJA1_MOUSE
NC score	0.479321 (rank : 24)	θ value	7.1131e-05 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	145	Shared Neighborhood Hits	87
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RNF11_HUMAN
NC score	0.478041 (rank : 25)	θ value	0.0113563 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
NC score	0.476495 (rank : 26)	θ value	0.0113563 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

AMFR_MOUSE
NC score	0.472861 (rank : 27)	θ value	6.43352e-06 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	208	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.471792 (rank : 28)	θ value	4.92598e-06 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	219	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

PJA1_HUMAN
NC score	0.469434 (rank : 29)	θ value	7.1131e-05 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	159	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

DZIP3_MOUSE
NC score	0.406824 (rank : 30)	θ value	6.43352e-06 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	414	Shared Neighborhood Hits	92
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DZIP3_HUMAN
NC score	0.406488 (rank : 31)	θ value	1.29631e-06 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	399	Shared Neighborhood Hits	93
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RN175_HUMAN
NC score	0.350583 (rank : 32)	θ value	0.00298849 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

ZSWM2_MOUSE
NC score	0.346703 (rank : 33)	θ value	0.00665767 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	132	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RBX2_MOUSE
NC score	0.325503 (rank : 34)	θ value	0.125558 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	82	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RBX2_HUMAN
NC score	0.324888 (rank : 35)	θ value	0.125558 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	83	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RN141_MOUSE
NC score	0.310855 (rank : 36)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	200	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

ZSWM2_HUMAN
NC score	0.310747 (rank : 37)	θ value	0.0431538 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN141_HUMAN
NC score	0.309674 (rank : 38)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	199	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN103_MOUSE
NC score	0.307433 (rank : 39)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	143	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RNF32_HUMAN
NC score	0.306982 (rank : 40)	θ value	0.0736092 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	133	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RN103_HUMAN
NC score	0.304756 (rank : 41)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RNF32_MOUSE
NC score	0.295479 (rank : 42)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

PEX10_HUMAN
NC score	0.290040 (rank : 43)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	255	Shared Neighborhood Hits	105
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

APC11_HUMAN
NC score	0.287995 (rank : 44)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

RAD18_MOUSE
NC score	0.285784 (rank : 45)	θ value	0.00035302 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	230	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAD18_HUMAN
NC score	0.285204 (rank : 46)	θ value	0.00020696 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	284	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

TOPRS_HUMAN
NC score	0.284732 (rank : 47)	θ value	0.00665767 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	286	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

APC11_MOUSE
NC score	0.283846 (rank : 48)	θ value	0.0961366 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

RNF4_HUMAN
NC score	0.283303 (rank : 49)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	212	Shared Neighborhood Hits	94
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.279912 (rank : 50)	θ value	0.0563607 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	212	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TOPRS_MOUSE
NC score	0.276585 (rank : 51)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	263	Shared Neighborhood Hits	99
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ZN363_MOUSE
NC score	0.273996 (rank : 52)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	134	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN363_HUMAN
NC score	0.266714 (rank : 53)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	162	Shared Neighborhood Hits	50
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

CHFR_MOUSE
NC score	0.257866 (rank : 54)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	88
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_HUMAN
NC score	0.252291 (rank : 55)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	255	Shared Neighborhood Hits	88
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TTC3_HUMAN
NC score	0.250855 (rank : 56)	θ value	0.00102713 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	664	Shared Neighborhood Hits	74
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

RNF8_MOUSE
NC score	0.248377 (rank : 57)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	618	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF8_HUMAN
NC score	0.238299 (rank : 58)	θ value	0.0736092 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	622	Shared Neighborhood Hits	104
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RBX1_HUMAN
NC score	0.236442 (rank : 59)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
NC score	0.236442 (rank : 60)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

DTX3_HUMAN
NC score	0.216473 (rank : 61)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

BRAP_MOUSE
NC score	0.215665 (rank : 62)	θ value	0.0563607 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

PCGF2_MOUSE
NC score	0.213402 (rank : 63)	θ value	0.0736092 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.212998 (rank : 64)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	222	Shared Neighborhood Hits	71
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

DTX3_MOUSE
NC score	0.210017 (rank : 65)	θ value	0.0431538 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	202	Shared Neighborhood Hits	73
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RNF41_MOUSE
NC score	0.205239 (rank : 66)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	224	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.205124 (rank : 67)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	226	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

DTX3L_HUMAN
NC score	0.203584 (rank : 68)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	187	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

PCGF4_HUMAN
NC score	0.192092 (rank : 69)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

BRAP_HUMAN
NC score	0.191515 (rank : 70)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	560	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

PCGF4_MOUSE
NC score	0.191445 (rank : 71)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	163	Shared Neighborhood Hits	69
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF6_HUMAN
NC score	0.164413 (rank : 72)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
NC score	0.163709 (rank : 73)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RNF25_MOUSE
NC score	0.157628 (rank : 74)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

TRAIP_MOUSE
NC score	0.149758 (rank : 75)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	745	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

CBLC_MOUSE
NC score	0.148974 (rank : 76)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RNF25_HUMAN
NC score	0.148474 (rank : 77)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

CBLC_HUMAN
NC score	0.147639 (rank : 78)	θ value	0.125558 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	173	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

TRAIP_HUMAN
NC score	0.141991 (rank : 79)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	780	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRIM2_HUMAN
NC score	0.141211 (rank : 80)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	330	Shared Neighborhood Hits	87
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.140695 (rank : 81)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	331	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
NC score	0.137119 (rank : 82)	θ value	0.0736092 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	357	Shared Neighborhood Hits	85
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

MYCB2_MOUSE
NC score	0.135518 (rank : 83)	θ value	0.0252991 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

CM007_MOUSE
NC score	0.135464 (rank : 84)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	416	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

MYCB2_HUMAN
NC score	0.132217 (rank : 85)	θ value	0.0252991 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	390	Shared Neighborhood Hits	41
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TRIM3_MOUSE
NC score	0.130935 (rank : 86)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

RN185_HUMAN
NC score	0.130843 (rank : 87)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	131	Target Neighborhood Hits	213	Shared Neighborhood Hits	83
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

LNX2_HUMAN
NC score	0.129770 (rank : 88)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	389	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
NC score	0.129254 (rank : 89)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	407	Shared Neighborhood Hits	81
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RN185_MOUSE
NC score	0.128513 (rank : 90)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	131	Target Neighborhood Hits	211	Shared Neighborhood Hits	81
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI65_HUMAN
NC score	0.126110 (rank : 91)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	330	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CM007_HUMAN
NC score	0.123280 (rank : 92)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	422	Shared Neighborhood Hits	78
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CBL_HUMAN
NC score	0.123038 (rank : 93)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	353	Shared Neighborhood Hits	70
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

PZRN3_MOUSE
NC score	0.122359 (rank : 94)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	447	Shared Neighborhood Hits	75
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LNX1_HUMAN
NC score	0.122050 (rank : 95)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	379	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PZRN3_HUMAN
NC score	0.122008 (rank : 96)	θ value	0.279714 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	461	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

CBL_MOUSE
NC score	0.121074 (rank : 97)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	426	Shared Neighborhood Hits	72
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

RFWD2_MOUSE
NC score	0.115809 (rank : 98)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	535	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.115764 (rank : 99)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	518	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

LNX1_MOUSE
NC score	0.114103 (rank : 100)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	377	Shared Neighborhood Hits	67
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RAPSN_HUMAN
NC score	0.113402 (rank : 101)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	131	Target Neighborhood Hits	84	Shared Neighborhood Hits	45
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
NC score	0.111716 (rank : 102)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	131	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

ZN313_HUMAN
NC score	0.109146 (rank : 103)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

R113A_HUMAN
NC score	0.108736 (rank : 104)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TRI65_MOUSE
NC score	0.108008 (rank : 105)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	131	Target Neighborhood Hits	340	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CBLB_HUMAN
NC score	0.107294 (rank : 106)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	131	Target Neighborhood Hits	261	Shared Neighborhood Hits	63
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
NC score	0.106965 (rank : 107)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

ZN313_MOUSE
NC score	0.105087 (rank : 108)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	131	Target Neighborhood Hits	273	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RING1_HUMAN
NC score	0.103210 (rank : 109)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	131	Target Neighborhood Hits	219	Shared Neighborhood Hits	54
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RNF5_HUMAN
NC score	0.102703 (rank : 110)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	131	Target Neighborhood Hits	206	Shared Neighborhood Hits	73
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.102585 (rank : 111)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	131	Target Neighborhood Hits	206	Shared Neighborhood Hits	74
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

ZN294_MOUSE
NC score	0.101396 (rank : 112)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

RING1_MOUSE
NC score	0.101213 (rank : 113)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	54
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

ZN294_HUMAN
NC score	0.101006 (rank : 114)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

RN146_HUMAN
NC score	0.099115 (rank : 115)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RBBP6_MOUSE
NC score	0.098360 (rank : 116)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	1014	Shared Neighborhood Hits	51
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RN146_MOUSE
NC score	0.098101 (rank : 117)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	161	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RING2_HUMAN
NC score	0.096002 (rank : 118)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	131	Target Neighborhood Hits	201	Shared Neighborhood Hits	57
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.095963 (rank : 119)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	131	Target Neighborhood Hits	199	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

R113B_HUMAN
NC score	0.095613 (rank : 120)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TRI35_HUMAN
NC score	0.092498 (rank : 121)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	382	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

PZRN4_HUMAN
NC score	0.088890 (rank : 122)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	438	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RN125_HUMAN
NC score	0.088039 (rank : 123)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	131	Target Neighborhood Hits	230	Shared Neighborhood Hits	63
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RBBP6_HUMAN
NC score	0.086473 (rank : 124)	θ value	0.21417 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRI13_MOUSE
NC score	0.085347 (rank : 125)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	131	Target Neighborhood Hits	282	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

BFAR_MOUSE
NC score	0.082935 (rank : 126)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	131	Target Neighborhood Hits	232	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI13_HUMAN
NC score	0.082928 (rank : 127)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	131	Target Neighborhood Hits	274	Shared Neighborhood Hits	82
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

BFAR_HUMAN
NC score	0.080546 (rank : 128)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	222	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RN166_MOUSE
NC score	0.080212 (rank : 129)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	131	Target Neighborhood Hits	248	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_HUMAN
NC score	0.079278 (rank : 130)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	131	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

MKRN3_MOUSE
NC score	0.079161 (rank : 131)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	137	Shared Neighborhood Hits	44
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

TRI25_MOUSE
NC score	0.077974 (rank : 132)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	446	Shared Neighborhood Hits	66
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

RN125_MOUSE
NC score	0.077465 (rank : 133)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI35_MOUSE
NC score	0.074250 (rank : 134)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	131	Target Neighborhood Hits	465	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

RN123_HUMAN
NC score	0.074217 (rank : 135)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	175	Shared Neighborhood Hits	48
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRI25_HUMAN
NC score	0.073574 (rank : 136)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	472	Shared Neighborhood Hits	64
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI40_HUMAN
NC score	0.070716 (rank : 137)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	131	Target Neighborhood Hits	279	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

MKRN4_HUMAN
NC score	0.069491 (rank : 138)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	147	Shared Neighborhood Hits	50
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

TRI59_MOUSE
NC score	0.068443 (rank : 139)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	131	Target Neighborhood Hits	292	Shared Neighborhood Hits	69
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.067348 (rank : 140)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

MKRN1_HUMAN
NC score	0.065089 (rank : 141)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MGRN1_HUMAN
NC score	0.064786 (rank : 142)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	131	Target Neighborhood Hits	192	Shared Neighborhood Hits	45
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MKRN3_HUMAN
NC score	0.063909 (rank : 143)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RN168_MOUSE
NC score	0.063503 (rank : 144)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	131	Target Neighborhood Hits	440	Shared Neighborhood Hits	56
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN123_MOUSE
NC score	0.063442 (rank : 145)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	174	Shared Neighborhood Hits	47
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

MGRN1_MOUSE
NC score	0.062877 (rank : 146)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	131	Target Neighborhood Hits	149	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

TRI39_HUMAN
NC score	0.062773 (rank : 147)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	131	Target Neighborhood Hits	693	Shared Neighborhood Hits	92
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI56_HUMAN
NC score	0.062115 (rank : 148)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	131	Target Neighborhood Hits	339	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI39_MOUSE
NC score	0.062085 (rank : 149)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	131	Target Neighborhood Hits	691	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

MKRN1_MOUSE
NC score	0.061769 (rank : 150)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

TRI37_HUMAN
NC score	0.061566 (rank : 151)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.061195 (rank : 152)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	131	Target Neighborhood Hits	316	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

BRCA1_HUMAN
NC score	0.060385 (rank : 153)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	131	Target Neighborhood Hits	381	Shared Neighborhood Hits	61
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

VPS11_MOUSE
NC score	0.059972 (rank : 154)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

AMFR1_HUMAN
NC score	0.059680 (rank : 155)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P26442	Gene names	AMFR
Domain Architecture	No domain graphic available
Description	Autocrine motility factor receptor precursor, isoform 1 (AMF receptor).

VPS11_HUMAN
NC score	0.059253 (rank : 156)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	131	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

TRI31_HUMAN
NC score	0.058452 (rank : 157)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	131	Target Neighborhood Hits	299	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

RN168_HUMAN
NC score	0.057996 (rank : 158)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	131	Target Neighborhood Hits	370	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

MARH2_MOUSE
NC score	0.056925 (rank : 159)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q99M02, Q8C4Q5	Gene names	March2
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 2 (Membrane-associated RING-CH protein II) (MARCH-II).

BRCA1_MOUSE
NC score	0.056658 (rank : 160)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	131	Target Neighborhood Hits	436	Shared Neighborhood Hits	58
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

MARH2_HUMAN
NC score	0.053628 (rank : 161)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0N8, Q8N5A3, Q96B78	Gene names	MARCH2, RNF172
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 2 (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172).

TRI73_HUMAN
NC score	0.053468 (rank : 162)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	131	Target Neighborhood Hits	258	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI56_MOUSE
NC score	0.053291 (rank : 163)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	131	Target Neighborhood Hits	255	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI26_MOUSE
NC score	0.052837 (rank : 164)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	131	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

SMRA3_HUMAN
NC score	0.051556 (rank : 165)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	131	Target Neighborhood Hits	265	Shared Neighborhood Hits	64
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI26_HUMAN
NC score	0.051354 (rank : 166)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	131	Target Neighborhood Hits	335	Shared Neighborhood Hits	69
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI74_HUMAN
NC score	0.051023 (rank : 167)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	131	Target Neighborhood Hits	249	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM8_HUMAN
NC score	0.050500 (rank : 168)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	131	Target Neighborhood Hits	650	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

GP110_MOUSE
NC score	0.039985 (rank : 169)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

APH1B_MOUSE
NC score	0.026353 (rank : 170)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C7N7, Q3U3B5, Q8CEC9	Gene names	Aph1b
Domain Architecture
Description	Gamma-secretase subunit APH-1B (APH-1b) (Aph-1beta).

APH1C_MOUSE
NC score	0.026131 (rank : 171)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCZ9, Q3U2R3	Gene names	Aph1c
Domain Architecture
Description	Putative gamma-secretase subunit APH-1C.

GCP3_HUMAN
NC score	0.023536 (rank : 172)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CW5, O43631, O60852, O60853, Q7Z4K1, Q96I79	Gene names	TUBGCP3, GCP3
Domain Architecture
Description	Gamma-tubulin complex component 3 (GCP-3) (Spindle pole body protein Spc98 homolog) (hSpc98) (hGCP3) (h104p).

DSPP_HUMAN
NC score	0.021218 (rank : 173)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	645	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GCP3_MOUSE
NC score	0.019047 (rank : 174)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P58854, Q6PDQ9	Gene names	Tubgcp3, Gcp3
Domain Architecture	No domain graphic available
Description	Gamma-tubulin complex component 3 (GCP-3).

UBF1_HUMAN
NC score	0.011586 (rank : 175)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	415	Shared Neighborhood Hits	6
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

MC5R_HUMAN
NC score	0.008958 (rank : 176)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	903	Shared Neighborhood Hits	5
SwissProt Accessions	P33032	Gene names	MC5R
Domain Architecture
Description	Melanocortin receptor 5 (MC5-R) (MC-2).

LEO1_HUMAN
NC score	0.008895 (rank : 177)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	958	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CCR5_MOUSE
NC score	0.002625 (rank : 178)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	633	Shared Neighborhood Hits	5
SwissProt Accessions	P51682, O35313, O35891, P97308, P97405, Q61867	Gene names	Ccr5, Cmkbr5
Domain Architecture
Description	C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (MIP-1 alpha receptor) (CD195 antigen).

CCR2_MOUSE
NC score	0.002096 (rank : 179)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	631	Shared Neighborhood Hits	5
SwissProt Accessions	P51683, Q61172	Gene names	Ccr2, Cmkbr2
Domain Architecture
Description	C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC receptor) (MCP-1 receptor) (CD192 antigen).

SALL2_HUMAN
NC score	0.000110 (rank : 180)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).