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Network neighborhood for query Sequence : APC11_HUMAN

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APC11_HUMAN
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

APC11_HUMAN
θ value	4.11246e-53 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

APC11_MOUSE
θ value	2.66562e-52 (rank : 2)	NC score	0.997841 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	75	Shared Neighborhood Hits	71
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

RBX1_HUMAN
θ value	1.16975e-15 (rank : 3)	NC score	0.831317 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
θ value	1.16975e-15 (rank : 4)	NC score	0.831317 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

RBX2_HUMAN
θ value	3.18553e-13 (rank : 5)	NC score	0.796047 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	3.18553e-13 (rank : 6)	NC score	0.796223 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RN139_HUMAN
θ value	0.0431538 (rank : 7)	NC score	0.289361 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	130	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
θ value	0.0431538 (rank : 8)	NC score	0.287995 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	131	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RNF24_HUMAN
θ value	0.0563607 (rank : 9)	NC score	0.338395 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	122	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	0.0736092 (rank : 10)	NC score	0.335100 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF12_MOUSE
θ value	0.0961366 (rank : 11)	NC score	0.305126 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	159	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RN122_HUMAN
θ value	0.125558 (rank : 12)	NC score	0.324590 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	0.125558 (rank : 13)	NC score	0.324478 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

SMRA3_MOUSE
θ value	0.163984 (rank : 14)	NC score	0.080574 (rank : 76)
Query Neighborhood Hits	74	Target Neighborhood Hits	267	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RNF12_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.285769 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	173	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

AMFR2_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.251634 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	0.279714 (rank : 17)	NC score	0.252928 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

MKRN3_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.125675 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RNF6_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.286309 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RN103_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.231090 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	0.365318 (rank : 21)	NC score	0.232511 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

BFAR_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.115818 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	222	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RN126_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.267383 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	126	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RNF38_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.291034 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	155	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

MKRN4_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.117989 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

ZN364_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.278636 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	140	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	0.62314 (rank : 27)	NC score	0.271466 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

BFAR_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.116397 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	232	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RN167_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.262765 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	157	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	0.813845 (rank : 30)	NC score	0.261201 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	157	Shared Neighborhood Hits	55
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF32_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.201986 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	133	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	0.813845 (rank : 32)	NC score	0.197542 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	129	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

TAF3_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.060129 (rank : 88)
Query Neighborhood Hits	74	Target Neighborhood Hits	568	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

RN126_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.264804 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RNF13_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.253502 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	147	Shared Neighborhood Hits	53
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.256081 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	164	Shared Neighborhood Hits	54
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

WDR24_HUMAN
θ value	1.06291 (rank : 37)	NC score	0.064231 (rank : 84)
Query Neighborhood Hits	74	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WDR24_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.051767 (rank : 99)
Query Neighborhood Hits	74	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

MKRN1_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.109693 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	141	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

RNF38_MOUSE
θ value	1.38821 (rank : 40)	NC score	0.279523 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	153	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

TRAIP_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.099711 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	780	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.099559 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	745	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

BRCA1_MOUSE
θ value	1.81305 (rank : 43)	NC score	0.067421 (rank : 82)
Query Neighborhood Hits	74	Target Neighborhood Hits	436	Shared Neighborhood Hits	22
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

MKRN1_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.107357 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	141	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN3_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.118055 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

TRIM3_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.063707 (rank : 86)
Query Neighborhood Hits	74	Target Neighborhood Hits	357	Shared Neighborhood Hits	43
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

GLTL2_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.011317 (rank : 107)
Query Neighborhood Hits	74	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N3T1, Q86T60, Q96C46, Q96DJ5	Gene names	GALNTL2
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase-like protein 2 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase-like protein 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase- like protein 2) (Polypeptide GalNAc transferase-like protein 2) (GalNAc-T-like protein 2) (pp-GaNTase-like protein 2).

RN165_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.260648 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

TAF3_MOUSE
θ value	2.36792 (rank : 49)	NC score	0.054543 (rank : 94)
Query Neighborhood Hits	74	Target Neighborhood Hits	463	Shared Neighborhood Hits	6
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

FRAS1_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.016908 (rank : 106)
Query Neighborhood Hits	74	Target Neighborhood Hits	759	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NFX1_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.046082 (rank : 100)
Query Neighborhood Hits	74	Target Neighborhood Hits	405	Shared Neighborhood Hits	19
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PJA1_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.211649 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	159	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.217634 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	145	Shared Neighborhood Hits	44
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RNF5_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.120797 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

SMRA3_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.069043 (rank : 81)
Query Neighborhood Hits	74	Target Neighborhood Hits	265	Shared Neighborhood Hits	25
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

BRCA1_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.065621 (rank : 83)
Query Neighborhood Hits	74	Target Neighborhood Hits	381	Shared Neighborhood Hits	23
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

DZIP3_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.156630 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	399	Shared Neighborhood Hits	47
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.168346 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	414	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

RN185_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.133207 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.132959 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	211	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF5_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.116672 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

ZN294_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.086907 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

ZN294_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.087066 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

FANCL_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.039726 (rank : 101)
Query Neighborhood Hits	74	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CR14, Q3TGY2, Q9D017	Gene names	Fancl, Phf9, Pog
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein FANCL (EC 6.3.2.-) (Fanconi anemia group L protein homolog) (Proliferation of germ cells protein).

TIF1B_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.036293 (rank : 102)
Query Neighborhood Hits	74	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.034685 (rank : 103)
Query Neighborhood Hits	74	Target Neighborhood Hits	276	Shared Neighborhood Hits	16
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

JAG1_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.005440 (rank : 108)
Query Neighborhood Hits	74	Target Neighborhood Hits	518	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

RNF8_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.105855 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	622	Shared Neighborhood Hits	54
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRIM3_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.056469 (rank : 93)
Query Neighborhood Hits	74	Target Neighborhood Hits	351	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

BAZ1B_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.023320 (rank : 105)
Query Neighborhood Hits	74	Target Neighborhood Hits	701	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.025191 (rank : 104)
Query Neighborhood Hits	74	Target Neighborhood Hits	394	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

RN175_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.155253 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

RNF11_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.201364 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.200681 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

BRAP_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.083061 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.094299 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	409	Shared Neighborhood Hits	52
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CBLC_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.052087 (rank : 97)
Query Neighborhood Hits	74	Target Neighborhood Hits	173	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CHFR_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.081454 (rank : 75)
Query Neighborhood Hits	74	Target Neighborhood Hits	255	Shared Neighborhood Hits	44
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.082296 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	264	Shared Neighborhood Hits	44
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CM007_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.060316 (rank : 87)
Query Neighborhood Hits	74	Target Neighborhood Hits	422	Shared Neighborhood Hits	38
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.064093 (rank : 85)
Query Neighborhood Hits	74	Target Neighborhood Hits	416	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DTX3_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.053138 (rank : 95)
Query Neighborhood Hits	74	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

GOLI_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.205575 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.207414 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

MKRN2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.074754 (rank : 78)
Query Neighborhood Hits	74	Target Neighborhood Hits	129	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.075186 (rank : 77)
Query Neighborhood Hits	74	Target Neighborhood Hits	130	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

PEX10_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.147471 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	255	Shared Neighborhood Hits	57
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RAD18_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.052234 (rank : 96)
Query Neighborhood Hits	74	Target Neighborhood Hits	230	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAPSN_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.057221 (rank : 90)
Query Neighborhood Hits	74	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.057528 (rank : 89)
Query Neighborhood Hits	74	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RN133_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.204046 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	108	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RN141_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.144825 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	199	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.145999 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	200	Shared Neighborhood Hits	49
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RNF25_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.051957 (rank : 98)
Query Neighborhood Hits	74	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RNF41_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.069676 (rank : 80)
Query Neighborhood Hits	74	Target Neighborhood Hits	226	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.069703 (rank : 79)
Query Neighborhood Hits	74	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.093863 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	212	Shared Neighborhood Hits	45
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.094700 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	212	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF8_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.098034 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	618	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TOPRS_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.086174 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	286	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.087598 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	263	Shared Neighborhood Hits	53
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRIM2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.056748 (rank : 91)
Query Neighborhood Hits	74	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.056627 (rank : 92)
Query Neighborhood Hits	74	Target Neighborhood Hits	331	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TTC3_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.099515 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	664	Shared Neighborhood Hits	50
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

ZN363_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.113913 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.117213 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	134	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.111124 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	151	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.119479 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

APC11_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.11246e-53 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

APC11_MOUSE
NC score	0.997841 (rank : 2)	θ value	2.66562e-52 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	75	Shared Neighborhood Hits	71
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

RBX1_HUMAN
NC score	0.831317 (rank : 3)	θ value	1.16975e-15 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
NC score	0.831317 (rank : 4)	θ value	1.16975e-15 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

RBX2_MOUSE
NC score	0.796223 (rank : 5)	θ value	3.18553e-13 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RBX2_HUMAN
NC score	0.796047 (rank : 6)	θ value	3.18553e-13 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RNF24_HUMAN
NC score	0.338395 (rank : 7)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	122	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
NC score	0.335100 (rank : 8)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RN122_HUMAN
NC score	0.324590 (rank : 9)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
NC score	0.324478 (rank : 10)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF12_MOUSE
NC score	0.305126 (rank : 11)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	159	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF38_HUMAN
NC score	0.291034 (rank : 12)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	155	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN139_HUMAN
NC score	0.289361 (rank : 13)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	130	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
NC score	0.287995 (rank : 14)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	131	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RNF6_HUMAN
NC score	0.286309 (rank : 15)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF12_HUMAN
NC score	0.285769 (rank : 16)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	173	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF38_MOUSE
NC score	0.279523 (rank : 17)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	153	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ZN364_HUMAN
NC score	0.278636 (rank : 18)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	140	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
NC score	0.271466 (rank : 19)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RN126_HUMAN
NC score	0.267383 (rank : 20)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	126	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
NC score	0.264804 (rank : 21)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN167_HUMAN
NC score	0.262765 (rank : 22)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	157	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
NC score	0.261201 (rank : 23)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	157	Shared Neighborhood Hits	55
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN165_HUMAN
NC score	0.260648 (rank : 24)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RNF13_MOUSE
NC score	0.256081 (rank : 25)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	164	Shared Neighborhood Hits	54
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF13_HUMAN
NC score	0.253502 (rank : 26)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	147	Shared Neighborhood Hits	53
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

AMFR_MOUSE
NC score	0.252928 (rank : 27)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.251634 (rank : 28)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RN103_MOUSE
NC score	0.232511 (rank : 29)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN103_HUMAN
NC score	0.231090 (rank : 30)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

PJA1_MOUSE
NC score	0.217634 (rank : 31)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	145	Shared Neighborhood Hits	44
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PJA1_HUMAN
NC score	0.211649 (rank : 32)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	159	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

GOLI_MOUSE
NC score	0.207414 (rank : 33)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	74	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
NC score	0.205575 (rank : 34)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	74	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RN133_HUMAN
NC score	0.204046 (rank : 35)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	74	Target Neighborhood Hits	108	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RNF32_HUMAN
NC score	0.201986 (rank : 36)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	133	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF11_HUMAN
NC score	0.201364 (rank : 37)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
NC score	0.200681 (rank : 38)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RNF32_MOUSE
NC score	0.197542 (rank : 39)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	129	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

DZIP3_MOUSE
NC score	0.168346 (rank : 40)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	414	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DZIP3_HUMAN
NC score	0.156630 (rank : 41)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	399	Shared Neighborhood Hits	47
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RN175_HUMAN
NC score	0.155253 (rank : 42)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

PEX10_HUMAN
NC score	0.147471 (rank : 43)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	74	Target Neighborhood Hits	255	Shared Neighborhood Hits	57
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN141_MOUSE
NC score	0.145999 (rank : 44)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	74	Target Neighborhood Hits	200	Shared Neighborhood Hits	49
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.144825 (rank : 45)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	74	Target Neighborhood Hits	199	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN185_HUMAN
NC score	0.133207 (rank : 46)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.132959 (rank : 47)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	211	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

MKRN3_HUMAN
NC score	0.125675 (rank : 48)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RNF5_HUMAN
NC score	0.120797 (rank : 49)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

ZSWM2_MOUSE
NC score	0.119479 (rank : 50)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	74	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

MKRN3_MOUSE
NC score	0.118055 (rank : 51)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MKRN4_HUMAN
NC score	0.117989 (rank : 52)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

ZN363_MOUSE
NC score	0.117213 (rank : 53)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	74	Target Neighborhood Hits	134	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

RNF5_MOUSE
NC score	0.116672 (rank : 54)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

BFAR_MOUSE
NC score	0.116397 (rank : 55)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	232	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BFAR_HUMAN
NC score	0.115818 (rank : 56)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	222	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

ZN363_HUMAN
NC score	0.113913 (rank : 57)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	74	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZSWM2_HUMAN
NC score	0.111124 (rank : 58)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	74	Target Neighborhood Hits	151	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

MKRN1_HUMAN
NC score	0.109693 (rank : 59)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	141	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
NC score	0.107357 (rank : 60)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	141	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

RNF8_HUMAN
NC score	0.105855 (rank : 61)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	622	Shared Neighborhood Hits	54
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRAIP_HUMAN
NC score	0.099711 (rank : 62)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	780	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
NC score	0.099559 (rank : 63)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	745	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TTC3_HUMAN
NC score	0.099515 (rank : 64)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	74	Target Neighborhood Hits	664	Shared Neighborhood Hits	50
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

RNF8_MOUSE
NC score	0.098034 (rank : 65)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	74	Target Neighborhood Hits	618	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF4_MOUSE
NC score	0.094700 (rank : 66)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	74	Target Neighborhood Hits	212	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

BRAP_MOUSE
NC score	0.094299 (rank : 67)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	74	Target Neighborhood Hits	409	Shared Neighborhood Hits	52
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

RNF4_HUMAN
NC score	0.093863 (rank : 68)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	74	Target Neighborhood Hits	212	Shared Neighborhood Hits	45
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TOPRS_MOUSE
NC score	0.087598 (rank : 69)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	74	Target Neighborhood Hits	263	Shared Neighborhood Hits	53
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ZN294_MOUSE
NC score	0.087066 (rank : 70)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

ZN294_HUMAN
NC score	0.086907 (rank : 71)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

TOPRS_HUMAN
NC score	0.086174 (rank : 72)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	74	Target Neighborhood Hits	286	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

BRAP_HUMAN
NC score	0.083061 (rank : 73)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	74	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

CHFR_MOUSE
NC score	0.082296 (rank : 74)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	74	Target Neighborhood Hits	264	Shared Neighborhood Hits	44
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_HUMAN
NC score	0.081454 (rank : 75)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	74	Target Neighborhood Hits	255	Shared Neighborhood Hits	44
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

SMRA3_MOUSE
NC score	0.080574 (rank : 76)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	267	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

MKRN2_MOUSE
NC score	0.075186 (rank : 77)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	74	Target Neighborhood Hits	130	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN2_HUMAN
NC score	0.074754 (rank : 78)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	74	Target Neighborhood Hits	129	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

RNF41_MOUSE
NC score	0.069703 (rank : 79)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	74	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.069676 (rank : 80)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	74	Target Neighborhood Hits	226	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SMRA3_HUMAN
NC score	0.069043 (rank : 81)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	265	Shared Neighborhood Hits	25
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

BRCA1_MOUSE
NC score	0.067421 (rank : 82)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	436	Shared Neighborhood Hits	22
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRCA1_HUMAN
NC score	0.065621 (rank : 83)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	381	Shared Neighborhood Hits	23
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

WDR24_HUMAN
NC score	0.064231 (rank : 84)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

CM007_MOUSE
NC score	0.064093 (rank : 85)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	74	Target Neighborhood Hits	416	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TRIM3_HUMAN
NC score	0.063707 (rank : 86)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	357	Shared Neighborhood Hits	43
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

CM007_HUMAN
NC score	0.060316 (rank : 87)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	74	Target Neighborhood Hits	422	Shared Neighborhood Hits	38
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TAF3_HUMAN
NC score	0.060129 (rank : 88)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	568	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

RAPSN_MOUSE
NC score	0.057528 (rank : 89)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	74	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_HUMAN
NC score	0.057221 (rank : 90)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	74	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

TRIM2_HUMAN
NC score	0.056748 (rank : 91)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	74	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.056627 (rank : 92)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	74	Target Neighborhood Hits	331	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_MOUSE
NC score	0.056469 (rank : 93)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	351	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TAF3_MOUSE
NC score	0.054543 (rank : 94)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	463	Shared Neighborhood Hits	6
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

DTX3_HUMAN
NC score	0.053138 (rank : 95)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	74	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RAD18_MOUSE
NC score	0.052234 (rank : 96)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	74	Target Neighborhood Hits	230	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

CBLC_HUMAN
NC score	0.052087 (rank : 97)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	74	Target Neighborhood Hits	173	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

RNF25_MOUSE
NC score	0.051957 (rank : 98)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	74	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

WDR24_MOUSE
NC score	0.051767 (rank : 99)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

NFX1_HUMAN
NC score	0.046082 (rank : 100)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	405	Shared Neighborhood Hits	19
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

FANCL_MOUSE
NC score	0.039726 (rank : 101)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CR14, Q3TGY2, Q9D017	Gene names	Fancl, Phf9, Pog
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein FANCL (EC 6.3.2.-) (Fanconi anemia group L protein homolog) (Proliferation of germ cells protein).

TIF1B_HUMAN
NC score	0.036293 (rank : 102)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.034685 (rank : 103)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	276	Shared Neighborhood Hits	16
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

BAZ1B_MOUSE
NC score	0.025191 (rank : 104)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	394	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ1B_HUMAN
NC score	0.023320 (rank : 105)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	701	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

FRAS1_HUMAN
NC score	0.016908 (rank : 106)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	759	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GLTL2_HUMAN
NC score	0.011317 (rank : 107)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N3T1, Q86T60, Q96C46, Q96DJ5	Gene names	GALNTL2
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase-like protein 2 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase-like protein 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase- like protein 2) (Polypeptide GalNAc transferase-like protein 2) (GalNAc-T-like protein 2) (pp-GaNTase-like protein 2).

JAG1_MOUSE
NC score	0.005440 (rank : 108)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	518	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).