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Network neighborhood for query Sequence : SQSTM_HUMAN

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SQSTM_HUMAN
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SQSTM_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).

SQSTM_MOUSE
θ value	0 (rank : 2)	NC score	0.979361 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q64337, Q99JM8	Gene names	Sqstm1, A170, STAP
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Ubiquitin-binding protein p62) (STONE14).

NBR1_HUMAN
θ value	1.53129e-07 (rank : 3)	NC score	0.349450 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

NBR1_MOUSE
θ value	8.40245e-06 (rank : 4)	NC score	0.315448 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	116	Shared Neighborhood Hits	17
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

MIB1_HUMAN
θ value	2.44474e-05 (rank : 5)	NC score	0.147328 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	470	Shared Neighborhood Hits	19
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	2.44474e-05 (rank : 6)	NC score	0.147566 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

HERC2_MOUSE
θ value	4.1701e-05 (rank : 7)	NC score	0.176242 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	167	Shared Neighborhood Hits	20
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
θ value	5.44631e-05 (rank : 8)	NC score	0.175540 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

MIB2_HUMAN
θ value	0.000158464 (rank : 9)	NC score	0.155027 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	438	Shared Neighborhood Hits	19
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
θ value	0.00020696 (rank : 10)	NC score	0.157516 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ZSWM2_HUMAN
θ value	0.0113563 (rank : 11)	NC score	0.202542 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	0.0148317 (rank : 12)	NC score	0.199368 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	132	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RP1L1_HUMAN
θ value	0.0193708 (rank : 13)	NC score	0.056779 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	1072	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

DTNA_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.155397 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	295	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

SETBP_MOUSE
θ value	0.0961366 (rank : 15)	NC score	0.088263 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

DTNA_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.153451 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	264	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

DTNB_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.144891 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	255	Shared Neighborhood Hits	18
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

MAGE1_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.031010 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	1389	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP4_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.052178 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	428	Shared Neighborhood Hits	11
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NFH_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.021375 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	1242	Shared Neighborhood Hits	19
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SETBP_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.082830 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

DTNB_MOUSE
θ value	0.365318 (rank : 22)	NC score	0.139134 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	263	Shared Neighborhood Hits	19
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

PACN3_MOUSE
θ value	0.47712 (rank : 23)	NC score	0.050460 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	380	Shared Neighborhood Hits	5
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

EP300_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.086549 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	821	Shared Neighborhood Hits	30
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

PACN3_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.048987 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	385	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PML_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.051607 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

CBP_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.081427 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	941	Shared Neighborhood Hits	29
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.078165 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	1051	Shared Neighborhood Hits	28
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

KPCE_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.007882 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.007154 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	906	Shared Neighborhood Hits	6
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

TCAL3_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.032001 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

HCN4_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.018801 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	284	Shared Neighborhood Hits	11
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

ARID2_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.036872 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	302	Shared Neighborhood Hits	8
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

CSPG3_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.012672 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	657	Shared Neighborhood Hits	11
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MAGC1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.034061 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PDXL2_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.046504 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

JHD2B_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.017799 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

RGS3_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.027556 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	1621	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TACC3_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.026103 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	779	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

MINT_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.035466 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	1291	Shared Neighborhood Hits	20
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MP2K5_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.007468 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	837	Shared Neighborhood Hits	7
SwissProt Accessions	Q13163	Gene names	MAP2K5, MEK5, MKK5, PRKMK5
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

MP2K5_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.007024 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	840	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVS7, Q8CFM3, Q8K360, Q9D222	Gene names	Map2k5, Mek5, Mkk5, Prkmk5
Domain Architecture	No domain graphic available
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

MTSS1_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.034924 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	592	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PCSK7_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.018475 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

TAU_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.049079 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	502	Shared Neighborhood Hits	14
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

SYNG_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.019227 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TP53B_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.043618 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	413	Shared Neighborhood Hits	13
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BTBDC_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.025029 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	248	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CDT1_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.019519 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

MAP1A_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.020970 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	1626	Shared Neighborhood Hits	25
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MO4L2_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.015365 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

MTSS1_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.032080 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	504	Shared Neighborhood Hits	11
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

PHF22_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.024241 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

TARA_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.018504 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	1626	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ABCF1_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.014727 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

AMZ1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.024507 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q400G9, Q8TF51	Gene names	AMZ1, KIAA1950
Domain Architecture	No domain graphic available
Description	Archaemetzincin-1 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 1).

HIC1_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.000299 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	838	Shared Neighborhood Hits	7
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HIC1_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.000783 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	863	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

IRX4_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.007645 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

SRRM2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.034467 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	1470	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WEE1_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.006822 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	777	Shared Neighborhood Hits	8
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

DRP2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.051387 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	186	Shared Neighborhood Hits	10
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

Hits sorted by NC score

SQSTM_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).

SQSTM_MOUSE
NC score	0.979361 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q64337, Q99JM8	Gene names	Sqstm1, A170, STAP
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Ubiquitin-binding protein p62) (STONE14).

NBR1_HUMAN
NC score	0.349450 (rank : 3)	θ value	1.53129e-07 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

NBR1_MOUSE
NC score	0.315448 (rank : 4)	θ value	8.40245e-06 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	116	Shared Neighborhood Hits	17
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

ZSWM2_HUMAN
NC score	0.202542 (rank : 5)	θ value	0.0113563 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
NC score	0.199368 (rank : 6)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	132	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

HERC2_MOUSE
NC score	0.176242 (rank : 7)	θ value	4.1701e-05 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	167	Shared Neighborhood Hits	20
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.175540 (rank : 8)	θ value	5.44631e-05 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

MIB2_MOUSE
NC score	0.157516 (rank : 9)	θ value	0.00020696 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

DTNA_HUMAN
NC score	0.155397 (rank : 10)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	295	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

MIB2_HUMAN
NC score	0.155027 (rank : 11)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	438	Shared Neighborhood Hits	19
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

DTNA_MOUSE
NC score	0.153451 (rank : 12)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	264	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

MIB1_MOUSE
NC score	0.147566 (rank : 13)	θ value	2.44474e-05 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB1_HUMAN
NC score	0.147328 (rank : 14)	θ value	2.44474e-05 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	470	Shared Neighborhood Hits	19
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

DTNB_HUMAN
NC score	0.144891 (rank : 15)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	255	Shared Neighborhood Hits	18
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

DTNB_MOUSE
NC score	0.139134 (rank : 16)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	263	Shared Neighborhood Hits	19
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

SETBP_MOUSE
NC score	0.088263 (rank : 17)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

EP300_HUMAN
NC score	0.086549 (rank : 18)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	821	Shared Neighborhood Hits	30
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

SETBP_HUMAN
NC score	0.082830 (rank : 19)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CBP_HUMAN
NC score	0.081427 (rank : 20)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	941	Shared Neighborhood Hits	29
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
NC score	0.078165 (rank : 21)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	1051	Shared Neighborhood Hits	28
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RP1L1_HUMAN
NC score	0.056779 (rank : 22)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	1072	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MAP4_HUMAN
NC score	0.052178 (rank : 23)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	428	Shared Neighborhood Hits	11
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PML_MOUSE
NC score	0.051607 (rank : 24)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

DRP2_HUMAN
NC score	0.051387 (rank : 25)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	186	Shared Neighborhood Hits	10
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

PACN3_MOUSE
NC score	0.050460 (rank : 26)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	380	Shared Neighborhood Hits	5
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

TAU_MOUSE
NC score	0.049079 (rank : 27)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	502	Shared Neighborhood Hits	14
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PACN3_HUMAN
NC score	0.048987 (rank : 28)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	385	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PDXL2_MOUSE
NC score	0.046504 (rank : 29)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

TP53B_HUMAN
NC score	0.043618 (rank : 30)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	413	Shared Neighborhood Hits	13
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ARID2_HUMAN
NC score	0.036872 (rank : 31)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	302	Shared Neighborhood Hits	8
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

MINT_HUMAN
NC score	0.035466 (rank : 32)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	1291	Shared Neighborhood Hits	20
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MTSS1_MOUSE
NC score	0.034924 (rank : 33)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	592	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

SRRM2_MOUSE
NC score	0.034467 (rank : 34)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	1470	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MAGC1_HUMAN
NC score	0.034061 (rank : 35)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MTSS1_HUMAN
NC score	0.032080 (rank : 36)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	504	Shared Neighborhood Hits	11
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

TCAL3_MOUSE
NC score	0.032001 (rank : 37)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

MAGE1_HUMAN
NC score	0.031010 (rank : 38)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	1389	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RGS3_MOUSE
NC score	0.027556 (rank : 39)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	1621	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TACC3_HUMAN
NC score	0.026103 (rank : 40)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	779	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

BTBDC_HUMAN
NC score	0.025029 (rank : 41)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	248	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

AMZ1_HUMAN
NC score	0.024507 (rank : 42)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q400G9, Q8TF51	Gene names	AMZ1, KIAA1950
Domain Architecture	No domain graphic available
Description	Archaemetzincin-1 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 1).

PHF22_HUMAN
NC score	0.024241 (rank : 43)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

NFH_HUMAN
NC score	0.021375 (rank : 44)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	1242	Shared Neighborhood Hits	19
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAP1A_HUMAN
NC score	0.020970 (rank : 45)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	1626	Shared Neighborhood Hits	25
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CDT1_HUMAN
NC score	0.019519 (rank : 46)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

SYNG_HUMAN
NC score	0.019227 (rank : 47)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

HCN4_MOUSE
NC score	0.018801 (rank : 48)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	284	Shared Neighborhood Hits	11
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

TARA_HUMAN
NC score	0.018504 (rank : 49)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	1626	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PCSK7_HUMAN
NC score	0.018475 (rank : 50)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

JHD2B_MOUSE
NC score	0.017799 (rank : 51)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

MO4L2_HUMAN
NC score	0.015365 (rank : 52)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

ABCF1_HUMAN
NC score	0.014727 (rank : 53)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

CSPG3_MOUSE
NC score	0.012672 (rank : 54)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	657	Shared Neighborhood Hits	11
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KPCE_HUMAN
NC score	0.007882 (rank : 55)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

IRX4_MOUSE
NC score	0.007645 (rank : 56)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

MP2K5_HUMAN
NC score	0.007468 (rank : 57)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	837	Shared Neighborhood Hits	7
SwissProt Accessions	Q13163	Gene names	MAP2K5, MEK5, MKK5, PRKMK5
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

KPCE_MOUSE
NC score	0.007154 (rank : 58)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	906	Shared Neighborhood Hits	6
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

MP2K5_MOUSE
NC score	0.007024 (rank : 59)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	840	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVS7, Q8CFM3, Q8K360, Q9D222	Gene names	Map2k5, Mek5, Mkk5, Prkmk5
Domain Architecture	No domain graphic available
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

WEE1_HUMAN
NC score	0.006822 (rank : 60)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	777	Shared Neighborhood Hits	8
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

HIC1_MOUSE
NC score	0.000783 (rank : 61)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	863	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

HIC1_HUMAN
NC score	0.000299 (rank : 62)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	838	Shared Neighborhood Hits	7
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).