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Network neighborhood for query Sequence : COE3_HUMAN

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COE3_HUMAN
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COE1_HUMAN
θ value	0 (rank : 1)	NC score	0.991636 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UH73, Q8IW11	Gene names	EBF1, COE1, EBF
Domain Architecture
Description	Transcription factor COE1 (OE-1) (O/E-1) (Early B-cell factor).

COE1_MOUSE
θ value	0 (rank : 2)	NC score	0.991636 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q07802	Gene names	Ebf1, Coe1, Ebf
Domain Architecture
Description	Transcription factor COE1 (OE-1) (O/E-1) (Early B-cell factor).

COE2_MOUSE
θ value	0 (rank : 3)	NC score	0.992884 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	O08792, Q543D5	Gene names	Ebf2, Coe2, Mmot1
Domain Architecture
Description	Transcription factor COE2 (Early B-cell factor 2) (EBF-2) (Olf-1/EBF- like 3) (OE-3) (O/E-3) (Metencephalon-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory TF1).

COE3_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE3_MOUSE
θ value	0 (rank : 5)	NC score	0.997575 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	57
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE4_HUMAN
θ value	0 (rank : 6)	NC score	0.991072 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQW3, Q5JY53, Q9NUB6, Q9P2A6	Gene names	EBF4, COE4, KIAA1442
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

COE4_MOUSE
θ value	0 (rank : 7)	NC score	0.991793 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J2, Q8K4J1, Q8K4J3, Q8K4J4, Q8K4J5	Gene names	Ebf4, Coe4
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

YTHD3_HUMAN
θ value	0.00228821 (rank : 8)	NC score	0.075510 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z739, Q63Z37, Q659A3	Gene names	YTHDF3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

RBM14_HUMAN
θ value	0.0252991 (rank : 9)	NC score	0.038294 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

RBM14_MOUSE
θ value	0.0330416 (rank : 10)	NC score	0.037528 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

GLI2_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.011444 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	971	Shared Neighborhood Hits	19
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ANK3_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.010512 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	853	Shared Neighborhood Hits	11
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

YTHD3_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.093025 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

FUS_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.018327 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

NKX61_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.012843 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

PLXA1_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.029706 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

CDSN_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.041203 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	131	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

FOXF2_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.011238 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

HRX_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.017446 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	825	Shared Neighborhood Hits	13
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TROP_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.014988 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q12816, Q9NU89, Q9UPN8	Gene names	TRO, KIAA1114, MAGED3
Domain Architecture
Description	Trophinin (MAGE-D3 antigen).

AUXI_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.023251 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

DPOA2_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.032052 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q14181, Q9BPV3	Gene names	POLA2
Domain Architecture
Description	DNA polymerase subunit alpha B (DNA polymerase alpha 70 kDa subunit).

NUP62_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.019165 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

PHF2_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.019289 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	208	Shared Neighborhood Hits	8
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ADRM1_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.042332 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

ADRM1_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.041910 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

HNRL1_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.019015 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

NUPL_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.015022 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	68	Shared Neighborhood Hits	5
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

PHF22_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.029032 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

ANC1_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.045135 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

CTND2_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.014054 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	333	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

EPC1_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.017770 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

FOXGA_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.011657 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

HXB5_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.006384 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	337	Shared Neighborhood Hits	5
SwissProt Accessions	P09079, Q3ZAY8	Gene names	Hoxb5, Hox-2.1, Hoxb-5
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1).

K22O_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.004514 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	485	Shared Neighborhood Hits	6
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

MAST2_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.002617 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	1189	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NECD_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.013960 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

RPB1_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.020593 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	362	Shared Neighborhood Hits	14
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.020517 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	363	Shared Neighborhood Hits	14
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

UBE4B_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.019099 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ANC1_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.051184 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

CDKL5_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.005108 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	967	Shared Neighborhood Hits	12
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

MUC7_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.009107 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	538	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PCGF2_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.013579 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PHF2_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.016377 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	241	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

RBM16_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.058725 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	300	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

SIP1_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.002767 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	870	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

T240L_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.014415 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

ARNT_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.011255 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

AUXI_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.021946 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

BCAR3_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.020028 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

CASC5_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.016912 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

IRK10_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.019305 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P78508, Q8N4I7, Q92808	Gene names	KCNJ10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) (ATP-dependent inwardly rectifying potassium channel Kir4.1).

MAST2_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.001996 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	1110	Shared Neighborhood Hits	12
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MUC5B_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.011088 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	1020	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NFRKB_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.014357 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	393	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

AF10_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.008777 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

BCAR3_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.018660 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

CDSN_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.022031 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q15517, O43509, Q5SQ85, Q5STD2, Q7LA70, Q7LA71, Q86Z04, Q8IZU4, Q8IZU5, Q8IZU6, Q8N5P3, Q95IF9, Q9NP52, Q9NPE0, Q9NPG5, Q9NRH4, Q9NRH5, Q9NRH6, Q9NRH7, Q9NRH8, Q9UBH8, Q9UIN6, Q9UIN7, Q9UIN8, Q9UIN9, Q9UIP0	Gene names	CDSN
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor (S protein).

DPOA2_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.019852 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P33611	Gene names	Pola2
Domain Architecture
Description	DNA polymerase subunit alpha B (DNA polymerase alpha 70 kDa subunit).

HCN4_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.003729 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

K2C6B_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.002034 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	506	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

KLF12_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.001063 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	717	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4X4, Q5VZM7, Q9UHZ0	Gene names	KLF12, AP2REP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

LARP4_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.013607 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

ANFY1_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.008588 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	480	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ATN1_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.009440 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	676	Shared Neighborhood Hits	13
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CNOT3_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.005563 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	425	Shared Neighborhood Hits	7
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO5A2_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.009492 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	760	Shared Neighborhood Hits	14
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

FUMH_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.008404 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P97807, Q99JL0, Q9DCX0	Gene names	Fh, Fh1
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase) (EF-3).

HRBL_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.011873 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HXB5_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.003291 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

IRK10_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.014828 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JM63	Gene names	Kcnj10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir4.1).

NPBL_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.003588 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	1041	Shared Neighborhood Hits	13
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PPRB_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.007977 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	354	Shared Neighborhood Hits	11
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RFWD2_MOUSE
θ value	8.99809 (rank : 75)	NC score	0.002247 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	535	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

SIP1_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.000898 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

Hits sorted by NC score

COE3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE3_MOUSE
NC score	0.997575 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	57
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE2_MOUSE
NC score	0.992884 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	O08792, Q543D5	Gene names	Ebf2, Coe2, Mmot1
Domain Architecture
Description	Transcription factor COE2 (Early B-cell factor 2) (EBF-2) (Olf-1/EBF- like 3) (OE-3) (O/E-3) (Metencephalon-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory TF1).

COE4_MOUSE
NC score	0.991793 (rank : 4)	θ value	0 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J2, Q8K4J1, Q8K4J3, Q8K4J4, Q8K4J5	Gene names	Ebf4, Coe4
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

COE1_HUMAN
NC score	0.991636 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UH73, Q8IW11	Gene names	EBF1, COE1, EBF
Domain Architecture
Description	Transcription factor COE1 (OE-1) (O/E-1) (Early B-cell factor).

COE1_MOUSE
NC score	0.991636 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q07802	Gene names	Ebf1, Coe1, Ebf
Domain Architecture
Description	Transcription factor COE1 (OE-1) (O/E-1) (Early B-cell factor).

COE4_HUMAN
NC score	0.991072 (rank : 7)	θ value	0 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQW3, Q5JY53, Q9NUB6, Q9P2A6	Gene names	EBF4, COE4, KIAA1442
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

YTHD3_MOUSE
NC score	0.093025 (rank : 8)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

YTHD3_HUMAN
NC score	0.075510 (rank : 9)	θ value	0.00228821 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z739, Q63Z37, Q659A3	Gene names	YTHDF3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

RBM16_HUMAN
NC score	0.058725 (rank : 10)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	300	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

ANC1_MOUSE
NC score	0.051184 (rank : 11)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ANC1_HUMAN
NC score	0.045135 (rank : 12)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ADRM1_HUMAN
NC score	0.042332 (rank : 13)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

ADRM1_MOUSE
NC score	0.041910 (rank : 14)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

CDSN_MOUSE
NC score	0.041203 (rank : 15)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	131	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

RBM14_HUMAN
NC score	0.038294 (rank : 16)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

RBM14_MOUSE
NC score	0.037528 (rank : 17)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

DPOA2_HUMAN
NC score	0.032052 (rank : 18)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q14181, Q9BPV3	Gene names	POLA2
Domain Architecture
Description	DNA polymerase subunit alpha B (DNA polymerase alpha 70 kDa subunit).

PLXA1_MOUSE
NC score	0.029706 (rank : 19)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

PHF22_HUMAN
NC score	0.029032 (rank : 20)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

AUXI_HUMAN
NC score	0.023251 (rank : 21)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

CDSN_HUMAN
NC score	0.022031 (rank : 22)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q15517, O43509, Q5SQ85, Q5STD2, Q7LA70, Q7LA71, Q86Z04, Q8IZU4, Q8IZU5, Q8IZU6, Q8N5P3, Q95IF9, Q9NP52, Q9NPE0, Q9NPG5, Q9NRH4, Q9NRH5, Q9NRH6, Q9NRH7, Q9NRH8, Q9UBH8, Q9UIN6, Q9UIN7, Q9UIN8, Q9UIN9, Q9UIP0	Gene names	CDSN
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor (S protein).

AUXI_MOUSE
NC score	0.021946 (rank : 23)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

RPB1_HUMAN
NC score	0.020593 (rank : 24)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	362	Shared Neighborhood Hits	14
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
NC score	0.020517 (rank : 25)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	363	Shared Neighborhood Hits	14
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

BCAR3_MOUSE
NC score	0.020028 (rank : 26)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

DPOA2_MOUSE
NC score	0.019852 (rank : 27)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P33611	Gene names	Pola2
Domain Architecture
Description	DNA polymerase subunit alpha B (DNA polymerase alpha 70 kDa subunit).

IRK10_HUMAN
NC score	0.019305 (rank : 28)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P78508, Q8N4I7, Q92808	Gene names	KCNJ10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) (ATP-dependent inwardly rectifying potassium channel Kir4.1).

PHF2_HUMAN
NC score	0.019289 (rank : 29)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	208	Shared Neighborhood Hits	8
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

NUP62_MOUSE
NC score	0.019165 (rank : 30)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

UBE4B_HUMAN
NC score	0.019099 (rank : 31)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

HNRL1_MOUSE
NC score	0.019015 (rank : 32)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

BCAR3_HUMAN
NC score	0.018660 (rank : 33)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

FUS_HUMAN
NC score	0.018327 (rank : 34)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

EPC1_MOUSE
NC score	0.017770 (rank : 35)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

HRX_HUMAN
NC score	0.017446 (rank : 36)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	825	Shared Neighborhood Hits	13
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CASC5_MOUSE
NC score	0.016912 (rank : 37)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

PHF2_MOUSE
NC score	0.016377 (rank : 38)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	241	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

NUPL_HUMAN
NC score	0.015022 (rank : 39)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	68	Shared Neighborhood Hits	5
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

TROP_HUMAN
NC score	0.014988 (rank : 40)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q12816, Q9NU89, Q9UPN8	Gene names	TRO, KIAA1114, MAGED3
Domain Architecture
Description	Trophinin (MAGE-D3 antigen).

IRK10_MOUSE
NC score	0.014828 (rank : 41)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JM63	Gene names	Kcnj10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir4.1).

T240L_MOUSE
NC score	0.014415 (rank : 42)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

NFRKB_MOUSE
NC score	0.014357 (rank : 43)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	393	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

CTND2_HUMAN
NC score	0.014054 (rank : 44)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	333	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

NECD_HUMAN
NC score	0.013960 (rank : 45)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

LARP4_HUMAN
NC score	0.013607 (rank : 46)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

PCGF2_HUMAN
NC score	0.013579 (rank : 47)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

NKX61_HUMAN
NC score	0.012843 (rank : 48)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

HRBL_HUMAN
NC score	0.011873 (rank : 49)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

FOXGA_HUMAN
NC score	0.011657 (rank : 50)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

GLI2_HUMAN
NC score	0.011444 (rank : 51)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	971	Shared Neighborhood Hits	19
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ARNT_MOUSE
NC score	0.011255 (rank : 52)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

FOXF2_HUMAN
NC score	0.011238 (rank : 53)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

MUC5B_HUMAN
NC score	0.011088 (rank : 54)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	1020	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ANK3_HUMAN
NC score	0.010512 (rank : 55)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	853	Shared Neighborhood Hits	11
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CO5A2_HUMAN
NC score	0.009492 (rank : 56)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	760	Shared Neighborhood Hits	14
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

ATN1_HUMAN
NC score	0.009440 (rank : 57)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	676	Shared Neighborhood Hits	13
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MUC7_HUMAN
NC score	0.009107 (rank : 58)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	538	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

AF10_MOUSE
NC score	0.008777 (rank : 59)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

ANFY1_HUMAN
NC score	0.008588 (rank : 60)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	480	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FUMH_MOUSE
NC score	0.008404 (rank : 61)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P97807, Q99JL0, Q9DCX0	Gene names	Fh, Fh1
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase) (EF-3).

PPRB_MOUSE
NC score	0.007977 (rank : 62)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	354	Shared Neighborhood Hits	11
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

HXB5_MOUSE
NC score	0.006384 (rank : 63)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	337	Shared Neighborhood Hits	5
SwissProt Accessions	P09079, Q3ZAY8	Gene names	Hoxb5, Hox-2.1, Hoxb-5
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1).

CNOT3_HUMAN
NC score	0.005563 (rank : 64)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	425	Shared Neighborhood Hits	7
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CDKL5_HUMAN
NC score	0.005108 (rank : 65)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	967	Shared Neighborhood Hits	12
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

K22O_HUMAN
NC score	0.004514 (rank : 66)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	485	Shared Neighborhood Hits	6
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

HCN4_MOUSE
NC score	0.003729 (rank : 67)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

NPBL_MOUSE
NC score	0.003588 (rank : 68)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	1041	Shared Neighborhood Hits	13
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

HXB5_HUMAN
NC score	0.003291 (rank : 69)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

SIP1_MOUSE
NC score	0.002767 (rank : 70)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	870	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

MAST2_HUMAN
NC score	0.002617 (rank : 71)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	1189	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

RFWD2_MOUSE
NC score	0.002247 (rank : 72)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	535	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

K2C6B_MOUSE
NC score	0.002034 (rank : 73)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	506	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

MAST2_MOUSE
NC score	0.001996 (rank : 74)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	1110	Shared Neighborhood Hits	12
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

KLF12_HUMAN
NC score	0.001063 (rank : 75)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	717	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4X4, Q5VZM7, Q9UHZ0	Gene names	KLF12, AP2REP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

SIP1_HUMAN
NC score	0.000898 (rank : 76)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).